|September 29, 2005
Exciting News on Potential Drug Treatments
Researchers have published studies that support a potential drug treatment for children with Progeria. Farnesyltransferase inhibitors (FTIs), originally developed for cancer, are capable of reversing the dramatic nuclear structure abnormalities that are the hallmark of cells from children with Progeria.
|July 01, 2005
Blocking Protein May Prove Useful in Treating Progeria
Blocking protein improves nuclear blebbing in mouse fibroblasts containing a targeted Hutchinson-Gilford Progeria syndrome mutation.
|March 21, 2005
abcnews.com Healthology Article Highlights Latest Findings
Reporter Christine Haran provides a top-line overview of Progeria and the current research findings reported in Nature and Journal of Pediatrics.
|March 06, 2005
Reversal of the cellular phenotype in the premature aging disease HGPS
Cells from patients with Hutchinson-Gilford Progeria Syndrome (HGPS) can be made healthy again, according to findings by scientists at the National Cancer Institute, part of the National Institutes of Health. Using specially modified short segments of DNA, NCI researchers Paola Scaffidi, PhD, and Tom Misteli, PhD (both 2003 PRF Workshop participants), reversed the defects seen in HGPS cells by eliminating the lamin A protein that is faulty in HGPS. By demonstrating that HGPS cellular phenotypes are reversible, this study brings scientists one step closer to curing this devastating childhood disease.
|February 05, 2005
Dr. Leslie Gordon Interviewed on CNN
Millions tuned in to CNN Live Weekend on Saturday, February 5th to watch a captivating interview with PRF Medical Director Dr. Leslie Gordon.
|January 30, 2005
Racing with Sam
The January 30th issue of the New York Times Magazine features the compelling story of PRF Medical Director Dr. Leslie Gordon, her husband Dr. Scott Berns, and their son Sam. The story, “Racing with Sam,” highlights the challenges faced by the Gordon and Berns family upon learning of Sam’s diagnosis of Progeria.