Exciting News on Potential Drug Treatments
Researchers have published studies that support a potential drug treatment for children with Progeria. Farnesyltransferase inhibitors (FTIs), originally developed for cancer, are capable of reversing the dramatic nuclear structure abnormalities that are the hallmark of cells from children with Progeria.
Here are some answers to Frequently Asked Questions about FTI's and these recent findings
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From the lab of Susan Michaelis at Johns Hopkins University School of Medicine and the University of Seattle. First author: Monica Mallampalli. PRF funded this study.
From the lab of Dr. Francis Collins at the National Human Genome Research Institute: First author: Brian Capell. Additional author: PRF's Medical Director Dr. Leslie Gordon)
From the lab of Drs. Loren Fong and Steven Young at UCLA. PRF helped fund this study.
From the lab of Dr. Thomas Glover at the University of Michigan. First author: Michael W. Glynn. PRF funded this study.
Here are just a few links to many media outlets that have covered this story:
ABCNEWS.COM
Cancer Drugs May Fight Rare Rapid-Aging Disease: Sept.29, 2005 (article no longer available)
LA TIMES
Research Shows Drugs Could Block Early-Aging Disease
FORBES
Cancer Drugs May Fight Rapid-Aging Disease (article no longer available)
REUTERS
Cancer Drugs May Treat Aging Syndrome in Children (article no longer available)
HEALTHNEWSDIGEST.COM
Blocking a Premature Aging Syndrome with Anticancer Drugs (article no longer available)