PRF Cell and Tissue Bank Publications
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- Fibroblast Cell Culture Protocol
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- PRF Cell and Tissue Bank Publications
Publications Stemming From
The Progeria Research Foundation Cell and Tissue Bank
The Progeria Research Foundation Cell and Tissue Bank has contributed to the following medical publications, categorized by cell line for researcher convenience:
For publications listed by cell line inclusion, click here.
Age-dependent loss of MMP-3 in
Hutchinson-Gilford progeria syndrome.
Harten IA, Zahr RS, Lemire JM, Machan JT, Moses MA, Doiron RJ, Curatolo AS, Rothman FG, Wight TN, Toole BP, Gordon LB. J Gerontol A Biol Sci Med Sci. 2011
Nov;66(11):1201-7.
Ageing-related chromatin defects through
loss of the NURD complex.
Pegoraro G, Kubben N, Wickert U, Göhler H, Hoffmann K, Misteli T. Nat Cell Biol. 2009 Oct;11(10):1261-7.
The mutant form
of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular
aging in human skin.
McClintock
D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K. PLoS One. 2007 Dec 5;2(12):e1269.
Hutchinson-Gilford progeria mutant lamin A primarily
targets human vascular cells as detected by an anti-Lamin A G608G antibody.
McClintock D, Gordon LB, Djabali K. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2154-9.
Aggrecan expression is substantially and abnormally
upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts.
Lemire JM, Patis C, Gordon LB, Sandy JD, Toole BP, Weiss AS. Mech Ageing Dev. 2006
Aug;127(8):660-9.
Rescue of heterochromatin organization in
Hutchinson-Gilford progeria by drug treatment.
Columbaro
M, Capanni
C, Mattioli
E, Novelli
G, Parnaik
VK, Squarzoni
S, Maraldi
NM, Lattanzi
G. Cell Mol Life Sci. 2005
Nov;62(22):2669-78.
Accumulation of mutant lamin A causes progressive
changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.
Goldman RD, Shumaker DK, Erdos MR, Eriksson M, Goldman AE, Gordon LB, Gruenbaum Y, Khuon S, Mendez M, Varga R, Collins FS. Proc Natl Acad Sci USA. 2004 Jun
15;101(24):8963-8.
Recurrent de
novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Eriksson
M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM,
Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW,
Collins FS. Nature. 2003 May
15;423(6937):293-8.
Age-dependent loss of MMP-3 in
Hutchinson-Gilford progeria syndrome.
Harten IA, Zahr RS, Lemire JM, Machan JT, Moses MA, Doiron RJ, Curatolo AS, Rothman FG, Wight TN, Toole BP, Gordon LB. J Gerontol A Biol Sci Med Sci. 2011
Nov;66(11):1201-7.
Progerin and
telomere dysfunction collaborate to trigger cellular senescence in normal human
fibroblasts.
Cao K, Blair CD, Faddah DA, Kieckhaefer JE, Olive M, Erdos MR, Nabel EG, Collins FS. J Clin Invest. 2011 Jul
1;121(7):2833-44
Defective
lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by
farnesyltransferase inhibition.
Marji
J, O'Donoghue SI, McClintock D, Satagopam VP, Schneider R, Ratner D, Worman HJ,
Gordon LB, Djabali K. PLoS One. 2010
Jun 15;5(6):e11132.
Effect
of progerin on the accumulation of oxidized proteins in fibroblasts from
Hutchinson Gilford progeria patients.
Viteri
G, Chung YW, Stadtman ER. Mech Ageing Dev.
2010 Jan;131(1):2-8.
Ageing-related chromatin defects through
loss of the NURD complex.
Pegoraro G, Kubben N, Wickert U, Göhler H, Hoffmann K, Misteli T. Nat Cell Biol. 2009 Oct;11(10):1261-7.
Lamin
A-dependent misregulation of adult stem cells associated with accelerated
ageing.
Scaffidi
P, Misteli T. Nat Cell Biol. 2008 Apr;10(4):452-9.
Perturbation
of wild-type lamin A metabolism results in a progeroid phenotype.
Candelario
J, Sudhakar S, Navarro S, Reddy S, Comai L. Aging
Cell. 2008 Jun;7(3):355-67
Alterations
in mitosis and cell cycle progression caused by a mutant lamin A known to
accelerate human aging.
Dechat T, Shimi T, Adam SA, Rusinol AE, Andres DA,
Spielmann HP, Sinensky MS, Goldman RD.
Proc Natl Acad Sci USA. 2007 Mar 20;104(12):4955-60.
The mutant form
of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular
aging in human skin.
McClintock
D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K. PLoS One. 2007 Dec 5;2(12):e1269.
A
lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome
interferes with mitosis in progeria and normal cells.
Cao K,
Capell BC, Erdos MR, Djabali K, Collins FS.
Proc Natl Acad Sci USA. 2007 Mar
20;104(12):4949-54.
Hutchinson-Gilford progeria mutant lamin A primarily
targets human vascular cells as detected by an anti-Lamin A G608G antibody.
McClintock D, Gordon LB, Djabali K. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2154-9.
Aggrecan expression is substantially and abnormally
upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts.
Lemire JM, Patis C, Gordon LB, Sandy JD, Toole BP, Weiss AS. Mech Ageing Dev. 2006 Aug;127(8):660-9.
Rescue of heterochromatin organization in
Hutchinson-Gilford progeria by drug treatment.
Columbaro
M, Capanni
C, Mattioli
E, Novelli
G, Parnaik
VK, Squarzoni
S, Maraldi
NM, Lattanzi
G. Cell Mol Life Sci. 2005
Nov;62(22):2669-78.
Genomic
instability in laminopathy-based premature aging.
Liu B,
Wang J, Chan KM, Tjia WM, Deng W, Guan X, Huang JD, Li KM, Chau PY, Chen DJ,
Pei D, Pendas AM, Cadiñanos J, López-Otín C, Tse HF, Hutchison C, Chen J, Cao
Y, Cheah KS, Tryggvason K, Zhou Z. Nat
Med. 2005 Jul;11(7):780-5.
Incomplete
processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear
abnormalities, which are reversed by farnesyltransferase inhibition.
Glynn MW, Glover TW. Hum Mol Genet. 2005 Oct
15;14(20):2959-69.
Accumulation of mutant lamin A causes progressive
changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.
Goldman RD, Shumaker DK, Erdos MR, Eriksson M, Goldman AE, Gordon LB, Gruenbaum Y, Khuon S, Mendez M, Varga R, Collins FS. Proc Natl Acad Sci U S A. 2004 Jun
15;101(24):8963-8.
Recurrent de
novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Eriksson
M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM,
Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW,
Collins FS. Nature. 2003 May
15;423(6937):293-8.
Incomplete
processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear
abnormalities, which are reversed by farnesyltransferase inhibition.
Glynn MW, Glover TW. Hum Mol Genet. 2005 Oct
15;14(20):2959-69.
Recurrent de
novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Eriksson
M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM,
Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW,
Collins FS. Nature. 2003 May
15;423(6937):293-8.
Recurrent de
novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Eriksson
M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM,
Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW,
Collins FS. Nature. 2003 May
15;423(6937):293-8.
Recurrent de
novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Eriksson
M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM,
Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW,
Collins FS. Nature. 2003 May
15;423(6937):293-8.
Increased
progerin expression associated with unusual LMNA mutations causes severe
progeroid syndromes.
Moulson
CL, Fong LG, Gardner JM, Farber EA, Go G, Passariello A, Grange DK, Young SG,
Miner JH. Hum Mutat. 2007
Sep;28(9):882-9.
Comparison of
constitutional and replication stress-induced genome structural variation by
SNP array and mate-pair sequencing.
Arlt
MF, Ozdemir AC, Birkeland SR, Lyons RH Jr, Glover TW, Wilson TE. Genetics. 2011 Mar;187(3):675-83.
Hydroxyurea
induces de novo copy number variants in human cells.
Arlt
MF, Ozdemir AC, Birkeland SR, Wilson TE, Glover TW. Proc Natl Acad Sci USA.
2011 Oct 18;108(42):17360-5
Progerin and
telomere dysfunction collaborate to trigger cellular senescence in normal human
fibroblasts.
Cao K, Blair CD, Faddah DA, Kieckhaefer JE, Olive M, Erdos MR, Nabel EG, Collins FS. J Clin Invest. 2011 Jul
1;121(7):2833-44
CTP:phosphocholine
cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure
without affecting phosphatidylcholine synthesis.
Gehrig
K, Ridgway ND. Biochim Biophys Acta.
2011 Jun;1811(6):377-85.
Effect of progerin on the accumulation of oxidized
proteins in fibroblasts from Hutchinson Gilford progeria patients.
Viteri G, Chung YW, Stadtman
ER. Mech Ageing Dev. 2010
Jan;131(1):2-8.
Replication
stress induces genome-wide copy number changes in human cells that resemble
polymorphic and pathogenic variants.
Arlt
MF, Mulle JG, Schaibley VM, Ragland RL, Durkin SG, Warren ST, Glover TW. Am J Hum Genet. 2009 Mar;84(3):339-50.
A lamin A protein isoform overexpressed in
Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and
normal cells.
Cao K, Capell BC, Erdos MR,
Djabali K, Collins FS. Proc Natl Acad Sci USA. 2007 Mar 20;104(12):4949-54.
Incomplete
processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear
abnormalities, which are reversed by farnesyltransferase inhibition.
Glynn MW, Glover TW. Hum Mol Genet. 2005 Oct
15;14(20):2959-69.
Age-dependent loss of MMP-3 in Hutchinson-Gilford
progeria syndrome.
Harten IA, Zahr RS, Lemire JM, Machan JT, Moses MA, Doiron RJ, Curatolo AS, Rothman FG, Wight TN, Toole BP, Gordon LB. J Gerontol A Biol Sci Med Sci. 2011
Nov;66(11):1201-7.
CTP:phosphocholine
cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure
without affecting phosphatidylcholine synthesis.
Gehrig
K, Ridgway ND. Biochim Biophys Acta.
2011 Jun;1811(6):377-85.
Defective
lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by
farnesyltransferase inhibition.
Marji
J, O'Donoghue SI, McClintock D, Satagopam VP, Schneider R, Ratner D, Worman HJ,
Gordon LB, Djabali K. PLoS One. 2010
Jun 15;5(6):e11132.
Increased
mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells:
effects of farnesyltransferase inhibitors.
Verstraeten
VL, Ji JY, Cummings KS, Lee RT, Lammerding J. Aging Cell. 2008 Jun;7(3):383-93.
Alterations
in mitosis and cell cycle progression caused by a mutant lamin A known to
accelerate human aging.
Dechat
T, Shimi T, Adam SA, Rusinol AE, Andres DA, Spielmann HP, Sinensky MS, Goldman
RD. Proc Natl Acad Sci USA. 2007 Mar
20;104(12):4955-60.
The mutant form
of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular
aging in human skin.
McClintock
D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K. PLoS One. 2007 Dec 5;2(12):e1269.
Aggrecan expression is substantially and abnormally
upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts.
Lemire JM, Patis C, Gordon LB, Sandy JD, Toole BP, Weiss AS. Mech Ageing Dev. 2006 Aug;127(8):660-9
Hutchinson-Gilford progeria mutant lamin A primarily
targets human vascular cells as detected by an anti-Lamin A G608G antibody.
McClintock D, Gordon LB, Djabali K. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2154-9.
Rescue of heterochromatin organization in
Hutchinson-Gilford progeria by drug treatment.
Columbaro
M, Capanni
C, Mattioli
E, Novelli
G, Parnaik
VK, Squarzoni
S, Maraldi
NM, Lattanzi
G. Cell Mol Life Sci. 2005
Nov;62(22):2669-78.
Genomic instability in laminopathy-based
premature aging.
Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X, Huang
JD, Li KM, Chau PY, Chen DJ, Pei D, Pendas AM, Cadiñanos J, López-Otín C, Tse
HF, Hutchison C, Chen J, Cao Y, Cheah KS, Tryggvason K, Zhou Z. Nat Med. 2005 Jul;11(7):780-5.
Novel
progerin-interactive partner proteins hnRNP E1, EGF, Mel 18, and UBC9 interact
with lamin A/C.
Zhong
N, Radu G, Ju W, Brown WT. Biochem
Biophys Res Commun. 2005 Dec 16;338(2):855-61.
Incomplete
processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear
abnormalities, which are reversed by farnesyltransferase inhibition.
Glynn MW, Glover TW. Hum Mol Genet. 2005 Oct
15;14(20):2959-69.
CTP:phosphocholine
cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure
without affecting phosphatidylcholine synthesis.
Gehrig
K, Ridgway ND. Biochim Biophys Acta.
2011 Jun;1811(6):377-85.
Increased
mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells:
effects of farnesyltransferase inhibitors.
Verstraeten
VL, Ji JY, Cummings KS, Lee RT, Lammerding J. Aging Cell. 2008 Jun;7(3):383-93.
The mutant form
of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular
aging in human skin.
McClintock
D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K. PLoS One. 2007 Dec 5;2(12):e1269.
Hutchinson-Gilford progeria mutant lamin A primarily
targets human vascular cells as detected by an anti-Lamin A G608G antibody.
McClintock D, Gordon LB, Djabali K. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2154-9.
Automated image analysis of
nuclear shape: What can we learn from a prematurely aged cell?
Driscoll MK, Albanese JL, Xiong ZM, Mailman M, Losert W, Cao K. Aging. 2012 Feb 16. [Epub ahead
of print]
Rapamycin reverses cellular phenotypes
and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome
cells.
Cao
K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS. Sci Transl Med. 2011 Jun
29;3(89):89ra58.
Defective
lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by
farnesyltransferase inhibition.
Marji J, O'Donoghue SI, McClintock D, Satagopam VP,
Schneider R, Ratner D, Worman HJ, Gordon LB, Djabali K. PLoS One. 2010 Jun 15;5(6):e11132.
Marji J, O'Donoghue SI, McClintock D, Satagopam VP, Schneider R, Ratner D, Worman HJ, Gordon LB, Djabali K. PLoS One. 2010 Jun 15;5(6):e11132.
Automated image analysis of
nuclear shape: What can we learn from a prematurely aged cell?
Driscoll MK, Albanese JL, Xiong ZM, Mailman M, Losert W, Cao K. Aging. 2012 Feb 16. [Epub ahead
of print]
Rapamycin
reverses cellular phenotypes and enhances mutant protein clearance in
Hutchinson-Gilford progeria syndrome cells.
Cao
K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS. Sci Transl Med. 2011 Jun
29;3(89):89ra58.
Progerin and
telomere dysfunction collaborate to trigger cellular senescence in normal human
fibroblasts.
Cao K, Blair CD, Faddah DA, Kieckhaefer JE, Olive M, Erdos MR, Nabel EG, Collins FS. J Clin Invest. 2011 Jul
1;121(7):2833-44
CTP:phosphocholine
cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure
without affecting phosphatidylcholine synthesis.
Gehrig
K, Ridgway ND. Biochim Biophys Acta.
2011 Jun;1811(6):377-85.
Effect of progerin on the accumulation of oxidized
proteins in fibroblasts from Hutchinson Gilford progeria patients.
Viteri G, Chung YW, Stadtman
ER. Mech Ageing Dev. 2010 Jan;131(1):2-8.
A lamin A protein isoform overexpressed in
Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and
normal cells.
Cao K, Capell BC, Erdos MR,
Djabali K, Collins FS. Proc Natl Acad Sci USA. 2007 Mar 20;104(12):4949-54.
Rapamycin
reverses cellular phenotypes and enhances mutant protein clearance in
Hutchinson-Gilford progeria syndrome cells.
Cao
K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS. Sci Transl Med. 2011 Jun
29;3(89):89ra58.
Progerin and
telomere dysfunction collaborate to trigger cellular senescence in normal human
fibroblasts.
Cao K, Blair CD, Faddah DA, Kieckhaefer JE, Olive M, Erdos MR, Nabel EG, Collins FS. J Clin Invest. 2011 Jul
1;121(7):2833-44
Effect of progerin on the accumulation of oxidized
proteins in fibroblasts from Hutchinson Gilford progeria patients.
Viteri G, Chung YW, Stadtman
ER. Mech Ageing Dev. 2010
Jan;131(1):2-8.
A lamin A protein isoform overexpressed in
Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and
normal cells.
Cao K, Capell BC, Erdos MR,
Djabali K, Collins FS. Proc Natl Acad Sci USA. 2007 Mar 20;104(12):4949-54.
Rapamycin
reverses cellular phenotypes and enhances mutant protein clearance in
Hutchinson-Gilford progeria syndrome cells.
Cao
K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS. Sci Transl Med. 2011 Jun
29;3(89):89ra58.
Defective
lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by
farnesyltransferase inhibition.
Marji
J, O'Donoghue SI, McClintock D, Satagopam VP, Schneider R, Ratner D, Worman HJ,
Gordon LB, Djabali K. PLoS One. 2010
Jun 15;5(6):e11132.
Rapamycin reverses cellular phenotypes
and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome
cells.
Cao
K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS. Sci Transl Med. 2011 Jun 29;3(89):89ra58.
Rapamycin
reverses cellular phenotypes and enhances mutant protein clearance in
Hutchinson-Gilford progeria syndrome cells.
Cao
K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS. Sci Transl Med. 2011 Jun
29;3(89):89ra58.
Stem cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011 Dec;10(6):1011-20.
doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Low and high expressing alleles of the LMNA gene:
implications for laminopathy disease development.
Rodríguez S, Eriksson M. PLoS One.
2011;6(9):e25472. Epub 2011 Sep 29.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Stem cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011
Dec;10(6):1011-20. doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Stem
cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011
Dec;10(6):1011-20. doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Low and high expressing alleles of the LMNA gene:
implications for laminopathy disease development.
Rodríguez S, Eriksson M. PLoS One.
2011;6(9):e25472. Epub 2011 Sep 29.
Recurrent
de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Stem
cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011 Dec;10(6):1011-20.
doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Stem cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011
Dec;10(6):1011-20. doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Stem cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011
Dec;10(6):1011-20. doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Stem cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011
Dec;10(6):1011-20. doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May 15;423(6937):293-8.
Epub 2003 Apr 25.
Stem
cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011
Dec;10(6):1011-20. doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Stem cell depletion in Hutchinson-Gilford progeria syndrome.
Rosengardten Y, McKenna T, Grochová D, Eriksson M. Aging Cell. 2011
Dec;10(6):1011-20. doi: 10.1111/j.1474-9726.2011.00743.x. Epub 2011 Oct 11.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.
Recurrent de novo point mutations in lamin A cause
Hutchinson-Gilford progeria syndrome.
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Nature. 2003 May
15;423(6937):293-8. Epub 2003 Apr 25.