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\u2013 \u0627\u0644\u0639\u0631\u0628\u064a\u0629\u201d _builder_version=\u201d4.21.0\u2033 background_layout=\u201ddark\u201d custom_margin=\u201d||10px\u201d button_text_size_tablet=\u201d18\u2033 button_text_size_phone=\u201d14\u2033 button_text_size_last_edited=\u201don|phone\u201d z_index_tablet=\u201d500\u2033 button_text_shadow_horizontal_length_tablet=\u201d0px\u201d \u0632\u0631 \u0627\u0644\u0646\u0635 \u0627\u0644\u0638\u0644 \u0627\u0644\u0639\u0645\u0648\u062f\u064a \u0644\u0644\u0637\u0648\u0644 = &quot;0 \u0628\u0643\u0633\u0644&quot; \u0632\u0631 \u0627\u0644\u0646\u0635 \u0627\u0644\u0638\u0644 \u0627\u0644\u0636\u0628\u0627\u0628\u064a \u0644\u0644\u0637\u0648\u0644 = &quot;1 \u0628\u0643\u0633\u0644&quot; \u0645\u0631\u0628\u0639 \u0627\u0644\u0638\u0644 \u0627\u0644\u0623\u0641\u0642\u064a \u0644\u0644\u0637\u0648\u0644 = &quot;0 \u0628\u0643\u0633\u0644&quot; \u0645\u0631\u0628\u0639 \u0627\u0644\u0638\u0644 \u0627\u0644\u0639\u0645\u0648\u062f\u064a 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\u0627\u0644\u0628\u0631\u062a\u063a\u0627\u0644\u064a&quot; _builder_version=&quot;4.19.4&quot; background_layout=&quot;dark&quot; custom_margin=&quot;||10px&quot; z_index_tablet=&quot;500&quot; button_text_shadow_horizontal_length_tablet=&quot;0px&quot; button_text_shadow_vertical_length_tablet=&quot;0px&quot; button_text_shadow_blur_strength_tablet=&quot;1px&quot; \u0635\u0646\u062f\u0648\u0642 \u0627\u0644\u0638\u0644 \u0627\u0644\u0623\u0641\u0642\u064a \u0644\u0644\u0637\u0627\u0648\u0644\u0629 = &quot;0 \u0628\u0643\u0633\u0644&quot; \u0635\u0646\u062f\u0648\u0642 \u0627\u0644\u0638\u0644 \u0627\u0644\u0639\u0645\u0648\u062f\u064a \u0644\u0644\u0637\u0627\u0648\u0644\u0629 = &quot;0 \u0628\u0643\u0633\u0644&quot; \u0635\u0646\u062f\u0648\u0642 \u0627\u0644\u0638\u0644 \u0627\u0644\u0636\u0628\u0627\u0628\u064a \u0644\u0644\u0637\u0627\u0648\u0644\u0629 = &quot;40 \u0628\u0643\u0633\u0644&quot; \u0635\u0646\u062f\u0648\u0642 \u0627\u0644\u0638\u0644 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button_text_shadow_vertical_length_tablet=&quot;0px&quot; button_text_shadow_blur_strength_tablet=&quot;1px&quot; box_shadow_horizontal_tablet=&quot;0px&quot; \u0635\u0646\u062f\u0648\u0642 \u0627\u0644\u0638\u0644 \u0627\u0644\u0639\u0645\u0648\u062f\u064a \u0644\u0644\u0637\u0627\u0648\u0644\u0629 = &quot;0 \u0628\u0643\u0633\u0644&quot; \u0635\u0646\u062f\u0648\u0642 \u0627\u0644\u0638\u0644 \u0627\u0644\u0636\u0628\u0627\u0628\u064a \u0644\u0644\u0637\u0627\u0648\u0644\u0629 = &quot;40 \u0628\u0643\u0633\u0644&quot; \u0635\u0646\u062f\u0648\u0642 \u0627\u0644\u0638\u0644 \u0627\u0644\u0645\u0646\u062a\u0634\u0631 \u0644\u0644\u0637\u0627\u0648\u0644\u0629 = &quot;0 \u0628\u0643\u0633\u0644&quot; global_colors_info = &quot;{}&quot;]<br \/>\n[\/et_pb_button][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner custom_padding_last_edited=\u201don|phone\u201d disabled_on=\u201don|on|off\u201d _builder_version=\u201d4.16\u2033 custom_padding=\u201d|35px|||false|false\u201d custom_padding_tablet=\u201d|35px||35px||true\u201d custom_padding_phone=\u201d\u201d animation_direction=\u201dtop\u201d z_index_tablet=\u201d500\u2033 global_colors_info=\u201d{}\u201d][et_pb_column_inner saved_specialty_column_type=\u201d3_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_text _builder_version=\u201d4.27.4\u2033 background_size=\u201dinitial\u201d background_position=\u201dtop_left\u201d background_repeat=\u201drepeat\u201d z_index_tablet=\u201d500\u2033 global_colors_info=\u201d{}\u201d]<\/p>\n<p>\u0639\u0646\u062f \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0647\u0630\u0647 \u0627\u0644\u0645\u0648\u0627\u062f \u0644\u0644\u062a\u0642\u0627\u0631\u064a\u0631 \u0623\u0648 \u0627\u0644\u0639\u0631\u0648\u0636 \u0627\u0644\u062a\u0642\u062f\u064a\u0645\u064a\u0629\u060c \u064a\u0631\u062c\u0649 \u062a\u0636\u0645\u064a\u0646 \u0645\u0627 \u064a\u0644\u064a:<br \/>\u0645\u0635\u062f\u0631:\u00a0<strong><em>\u062f\u0644\u064a\u0644 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0645\u0631\u0636 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629\u061b \u062f\u0644\u064a\u0644 \u0644\u0644\u0623\u0633\u0631 \u0648\u0645\u0642\u062f\u0645\u064a \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0644\u0644\u0623\u0637\u0641\u0627\u0644 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629.<\/em><\/strong><br \/>\u062c\u0645\u064a\u0639 \u0627\u0644\u062d\u0642\u0648\u0642 \u0645\u062d\u0641\u0648\u0638\u0629 \u0644\u0645\u0624\u0633\u0633\u0629 \u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 2019.<\/p>\n<p>\u0633\u0646\u0633\u062a\u0645\u0631 \u0641\u064a \u062a\u062d\u062f\u064a\u062b \u0647\u0630\u0647 \u0627\u0644\u0645\u0648\u0627\u062f \u0645\u0639 \u0648\u0631\u0648\u062f \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a. \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0644\u062f\u064a\u0643 \u0623\u0633\u0626\u0644\u0629 \u0637\u0628\u064a\u0629 \u0645\u062d\u062f\u062f\u0629\u060c \u064a\u0631\u062c\u0649 \u0627\u0644\u0627\u062a\u0635\u0627\u0644 \u0628\u0646\u0627 \u0639\u0644\u0649 (978) 535-2594 \u0623\u0648\u00a0<a href=\"mailto:info@progeriaresearch.org.\">info@progeriaresearch.org.<\/a><\/p>\n<p>\u0634\u0643\u0631\u064b\u0627 \u0644\u0643\u0644 \u0637\u0641\u0644 \u0648\u0623\u0633\u0631\u0629 \u064a\u0634\u0627\u0631\u0643\u0648\u0646 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u0645\u0634\u0627\u0631\u064a\u0639 \u0627\u0644\u0645\u0647\u0645\u0629 \u0644\u0644\u063a\u0627\u064a\u0629\u060c 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align_last_edited=\u201don|desktop\u201d admin_label=\u201d\u0635\u0648\u0631\u0629 \u0627\u0644\u063a\u0644\u0627\u0641 \u0628\u0627\u0644\u0644\u063a\u0629 \u0627\u0644\u0625\u0646\u062c\u0644\u064a\u0632\u064a\u0629 (\u0644\u0644\u0647\u0648\u0627\u062a\u0641 \u0627\u0644\u0645\u062d\u0645\u0648\u0644\u0629 \u0641\u0642\u0637)\u201d _builder_version=\u201d4.16\u2033 z_index_tablet=\u201d500\u2033 box_shadow_horizontal_tablet=\u201d0px\u201d box_shadow_vertical_tablet=\u201d0px\u201d box_shadow_blur_tablet=\u201d40px\u201d box_shadow_spread_tablet=\u201d0px\u201d global_colors_info=\u201d{}\u201d]<br \/>\n[\/et_pb_image][et_pb_text admin_label=&quot;\u0646\u0635 (\u0644\u0644\u062c\u0648\u0627\u0644 \u0641\u0642\u0637)&quot; _builder_version=&quot;4.16&quot; background_size=&quot;initial&quot; background_position=&quot;top_left&quot; background_repeat=&quot;repeat&quot; z_index_tablet=&quot;500&quot; global_colors_info=&quot;{}&quot;]<\/p>\n<p>\u0646\u0638\u0631\u064b\u0627 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button_url=&quot;https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2022\/11\/Manual-da-Progeria-2-ed.-Potugues-reduced-size-PDF.pdf&quot; url_new_window=&quot;on&quot; button_text=&quot;\u062a\u0646\u0632\u064a\u0644 \u0627\u0644\u0625\u0635\u062f\u0627\u0631 \u0627\u0644\u062b\u0627\u0646\u064a - \u0627\u0644\u0628\u0631\u062a\u063a\u0627\u0644\u064a\u0629&quot; admin_label=&quot;\u0627\u0644\u0625\u0635\u062f\u0627\u0631 \u0627\u0644\u064a\u0627\u0628\u0627\u0646\u064a \u0627\u0644\u062b\u0627\u0646\u064a&quot; _builder_version=&quot;4.18.1&quot; background_layout=&quot;dark&quot; custom_margin=&quot;||10px&quot; z_index_tablet=&quot;500&quot; button_text_shadow_horizontal_length_tablet=&quot;0px&quot; button_text_shadow_vertical_length_tablet=&quot;0px&quot; button_text_shadow_blur_strength_tablet=&quot;1px&quot; \u0635\u0646\u062f\u0648\u0642 \u0627\u0644\u0638\u0644 \u0627\u0644\u0623\u0641\u0642\u064a \u0644\u0644\u0637\u0627\u0648\u0644\u0629 = &quot;0 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\u0627\u0644\u062d\u0642\u0648\u0642 \u0645\u062d\u0641\u0648\u0638\u0629 \u0644\u0645\u0624\u0633\u0633\u0629 \u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 2019.<\/p>\n<p>\u0633\u0646\u0633\u062a\u0645\u0631 \u0641\u064a \u062a\u062d\u062f\u064a\u062b \u0647\u0630\u0647 \u0627\u0644\u0645\u0648\u0627\u062f \u0645\u0639 \u0648\u0631\u0648\u062f \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a. \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0644\u062f\u064a\u0643 \u0623\u0633\u0626\u0644\u0629 \u0637\u0628\u064a\u0629 \u0645\u062d\u062f\u062f\u0629\u060c \u064a\u0631\u062c\u0649 \u0627\u0644\u0627\u062a\u0635\u0627\u0644 \u0628\u0646\u0627 \u0639\u0644\u0649 (978) 535-2594 \u0623\u0648&nbsp;<a href=\"mailto:info@progeriaresearch.org.\">info@progeriaresearch.org.<\/a><\/p>\n<p>\u0634\u0643\u0631\u064b\u0627 \u0644\u0643\u0644 \u0637\u0641\u0644 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button_bg_color__hover_enabled=\u201don\u201d]<\/p>\n<h2>\u0627\u0634\u062a\u0631\u0627\u0643<\/h2>\n<h2>\u0645\u0646 \u0627\u062c\u0644\u0646\u0627<\/h2>\n<h2>\u0627\u0644\u062a\u062d\u062f\u064a\u062b\u0627\u062a!<\/h2>\n<p>[\/et_pb_cta][\/et_pb_column][et_pb_column type=&quot;1_4&quot; _builder_version=&quot;4.16&quot; custom_padding=&quot;|||&quot; global_colors_info=&quot;{}&quot; custom_padding__hover=&quot;|||&quot;][et_pb_cta button_url=&quot;https:\/\/progeriaresearch.donorsupport.co\/-\/XZHJVWZR&quot; button_text=&quot;\u062a\u0628\u0631\u0639 \u0627\u0644\u0622\u0646&quot; admin_label=&quot;\u0645\u0639\u064b\u0627\u060c \u0633\u0646\u0639\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c!&quot; module_class=\u201dsign-btn\u201d _builder_version=\u201d4.16\u2033 header_font_size=\u201d25px\u201d background_color=\u201d#29327a\u201d animation_style=\u201dslide\u201d animation_direction=\u201dleft\u201d animation_intensity_slide=\u201d25%\u201d header_font_size_tablet=\u201d\u201d header_font_size_phone=\u201d30px\u201d header_font_size_last_edited=\u201don|desktop\u201d body_font_size_tablet=\u201d\u201d body_font_size_phone=\u201d\u201d body_font_size_last_edited=\u201don|desktop\u201d z_index_tablet=\u201d500\u2033 border_radii=\u201don|25px|25px|25px|25px\u201d global_colors_info=\u201d{}\u201d button_bg_color__hover_enabled=\u201don\u201d button_bg_color__hover=\u201d#8fd2ed\u201d button_border_color__hover_enabled=\u201don\u201d]<\/p>\n<h2>\u0645\u0639\u0627 \u0646\u062d\u0646<\/h2>\n<h2><em>\u0633\u0648\u0641<\/em><\/h2>\n<h2>\u0627\u0628\u062d\u062b \u0639\u0646 \u0627\u0644\u0639\u0644\u0627\u062c!<\/h2>\n<p>[\/et_pb_cta][\/et_pb_column][et_pb_column type=\u201d1_2\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2025\/05\/2025-strip-for-website-footer-no-years.png\u201d title_text=\u201d\u0634\u0631\u064a\u0637 \u062a\u0630\u064a\u064a\u0644 \u0645\u0648\u0642\u0639 \u0627\u0644\u0648\u064a\u0628 \u0644\u0639\u0627\u0645 2025 \u0628\u062f\u0648\u0646 \u0633\u0646\u0648\u0627\u062a\u201d _builder_version=\u201d4.27.4\u2033 _module_preset=\u201ddefault\u201d custom_margin=\u201d35px||||false|false\u201d global_colors_info=\u201d{}\u201d][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>[et_pb_section fb_built=\u201d1\u2033 fullwidth=\u201don\u201d disabled_on=\u201doff|off|off\u201d _builder_version=\u201d4.16\u2033 border_width_bottom=\u201d55px\u201d border_color_bottom=\u201d#29327a\u201d locked=\u201doff\u201d global_colors_info=\u201d{}\u201d][et_pb_fullwidth_header _builder_version=\u201d4.24.3\u2033 title_font=\u201d||||||||\u201d \u062d\u062c\u0645 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[\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"\t\t\t\t[vc_row][vc_column][vc_custom_heading text=\"Patient Care and Handbook\" font_container=\"tag:h1|text_align:center\" use_theme_fonts=\"yes\"][vc_column_text]\r\n\r\n<img class=\"alignright size-full wp-image-4629\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/03\/english-front.jpg\" alt=\"\" width=\"200\" height=\"257\" \/>Because most medical caretakers have never treated a child with Progeria, there are often questions about how to optimize quality of life through daily care and medical treatment. To answer that need, in April 2010, PRF published\u00a0the first edition of <em>The Progeria Handbook<\/em>, for families touched by Progeria and their doctors. \u00a0From basic health facts to daily care recommendations to extensive treatment guidelines, this 131-page handbook helps answer many questions for children with Progeria throughout the world.\r\n\r\nIn March 2019, PRF updated and edited every section of the first edition of the handbook. Some of the biggest changes to the second edition include a new section on genetics and genetic counseling for the health professional, and a plethora of new information from recent clinical studies stemming from the Progeria research community, including new cardiovascular, neurovascular and endocrine information as well as recommendations.\r\n\r\n<img src=\"https:\/\/www.progeriaresearch.org\/assets\/images\/iconPDF.gif\" alt=\"\" width=\"34\" height=\"20\" \/> <a href=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/03\/PRF_Handbook_2019_eFile.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Click here<\/a> to download the second edition of the Handbook in English.\r\n\r\nWhen using these materials for reports or presentations, please include the following:\r\nSource:\u00a0<strong><em>The Progeria Handbook; A Guide for Families and Health Care Providers of Children with Progeria.<\/em><\/strong>\r\nCopyright 2019 by The Progeria Research Foundation. All rights reserved.\r\n\r\nWe will continue to update these materials as more information comes in. If you have specific medical questions, please contact us at (978) 535-2594 or\u00a0<a href=\"mailto:info@progeriaresearch.org.\">info@progeriaresearch.org.<\/a>\r\n\r\nThank you to every child and family who participates in these very important projects, and to the medical caretakers and other experts contributing to these recommendations.\r\n\r\n<hr \/>\r\n\r\nThe first edition of the handbook is available in Spanish and Portuguese versions. Translations of the second edition of the handbook in Spanish and Portuguese will be posted on this page when available.\r\n\r\n<img src=\"https:\/\/www.progeriaresearch.org\/assets\/images\/iconPDF.gif\" alt=\"\" width=\"34\" height=\"20\" \/> <a href=\"https:\/\/www.progeriaresearch.org\/assets\/files\/pdf\/Progeria_Book_r2.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Click here<\/a> to download the Portuguese version.\r\n\r\n<img src=\"https:\/\/www.progeriaresearch.org\/assets\/images\/iconPDF.gif\" alt=\"\" width=\"34\" height=\"20\" \/> <a href=\"https:\/\/www.progeriaresearch.org\/assets\/files\/pdf\/Progeria_Book_r2.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Clique aqui<\/a> para fazer o download da vers\u00e3o em Portugu\u00eas.\r\n\r\n<hr \/>\r\n\r\n<a href=\"https:\/\/www.progeriaresearch.org\/assets\/files\/pdf\/PRF%20Handbook%20Spanish.pdf\"><img src=\"https:\/\/www.progeriaresearch.org\/assets\/images\/iconPDF.gif\" alt=\"\" width=\"34\" height=\"20\" \/> <\/a><a href=\"https:\/\/www.progeriaresearch.org\/assets\/files\/pdf\/PRF%20Handbook%20Spanish.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Click here<\/a> to download the Spanish version.\r\n\r\n<a href=\"https:\/\/www.progeriaresearch.org\/assets\/files\/pdf\/PRF%20Handbook%20Spanish.pdf\"><img src=\"https:\/\/www.progeriaresearch.org\/assets\/images\/iconPDF.gif\" alt=\"\" width=\"34\" height=\"20\" \/> <\/a><a href=\"https:\/\/www.progeriaresearch.org\/assets\/files\/pdf\/PRF%20Handbook%20Spanish.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Haga clic aqui<\/a> para descargar la versi\u00f3n en espa\u00f1ol.[\/vc_column_text][\/vc_column][\/vc_row]\t\t","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-891","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>patient handbook | The 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