{"id":2047,"date":"2011-05-16T12:31:46","date_gmt":"2011-05-16T12:31:46","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=2047"},"modified":"2020-12-10T17:54:48","modified_gmt":"2020-12-10T22:54:48","slug":"groundbreaking-study-on-progeria-aging-link","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/fr\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/","title":{"rendered":"\u00c9tude r\u00e9volutionnaire sur le lien entre la prog\u00e9ria et le vieillissement"},"content":{"rendered":"<p>[et_pb_section fb_built=\u201d1\u2033 _builder_version=\u201d3.22\u2033][et_pb_row _builder_version=\u201d3.25\u2033 background_size=\u201dinitial\u201d background_position=\u201dtop_left\u201d background_repeat=\u201dr\u00e9p\u00e9ter\u201d][et_pb_column type=\u201d4_4\u2033 _builder_version=\u201d3.25\u2033 custom_padding=\u201d|||\u201d custom_padding__hover=\u201d|||\u201d][et_pb_text _builder_version=\u201d4.6.5\u2033 background_size=\u201dinitial\u201d background_position=\u201dtop_left\u201d background_repeat=\u201dr\u00e9p\u00e9ter\u201d hover_enabled=\u201d0\u2033 sticky_enabled=\u201d0\u2033]<\/p>\n<p>Le lien captivant entre la prog\u00e9ria et le vieillissement continue de se renforcer, alors que les chercheurs du NIH d\u00e9couvrent un lien entre les t\u00e9lom\u00e8res et la prog\u00e9rine.<\/p>\n<p class=\"yiv314624100msonormal\"><a href=\"https:\/\/www.cbsnews.com\/news\/clues-about-how-we-age-found-in-genetic-disorder\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2052\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/Capture.png\" alt=\"\" width=\"427\" height=\"279\" srcset=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/Capture.png 427w, https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/Capture-300x196.png 300w\" sizes=\"(max-width: 427px) 100vw, 427px\" \/><\/a>Des chercheurs des National Institutes of Health ont d\u00e9couvert un lien jusqu&#039;alors inconnu entre la prog\u00e9ria et le vieillissement. Les r\u00e9sultats apportent des informations sur la relation entre la prot\u00e9ine toxique \u00e0 l&#039;origine de la prog\u00e9ria, connue sous le nom de <strong>prog\u00e9rine <\/strong>et <strong>t\u00e9lom\u00e8res<\/strong>, qui prot\u00e8gent les extr\u00e9mit\u00e9s de l\u2019ADN dans les cellules jusqu\u2019\u00e0 ce qu\u2019elles s\u2019usent avec le temps et que les cellules meurent.<\/p>\n<p class=\"yiv314624100msonormal\">L&#039;\u00e9tude* est parue dans l&#039;\u00e9dition en ligne du 13 juin 2011 du Journal of Clinical Investigation. Elle conclut que dans le vieillissement normal, les t\u00e9lom\u00e8res courts ou dysfonctionnels stimulent les cellules \u00e0 produire de la prog\u00e9rine, qui est associ\u00e9e aux dommages cellulaires li\u00e9s \u00e0 l&#039;\u00e2ge.<\/p>\n<div id=\"attachment_2048\" style=\"width: 410px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2048\" class=\"wp-image-2048 size-full\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg\" alt=\"\" width=\"400\" height=\"159\" srcset=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg 400w, https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel-300x119.jpg 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><p id=\"caption-attachment-2048\" class=\"wp-caption-text\">Les cellules exprimant la prog\u00e9rine provenant d&#039;individus normaux pr\u00e9sentent des signes de s\u00e9nescence. L&#039;ADN du noyau est color\u00e9 en bleu. Les t\u00e9lom\u00e8res sont visibles sous forme de points rouges.<\/p><\/div>\n<p class=\"yiv314624100msonormal\">\u201c<strong>\u00ab Pour la premi\u00e8re fois, nous savons que le raccourcissement et le dysfonctionnement des t\u00e9lom\u00e8res influencent la production de prog\u00e9rine \u00bb, explique le Dr Leslie B. Gordon, directrice m\u00e9dicale de la Progeria Research Foundation. \u00ab Ces deux processus, qui influencent tous deux le vieillissement cellulaire, sont donc en r\u00e9alit\u00e9 li\u00e9s. \u00bb<\/strong><\/p>\n<p class=\"yiv314624100msonormal\">Des recherches ant\u00e9rieures ont montr\u00e9 que la prog\u00e9rine n\u2019est pas seulement produite chez les enfants atteints de prog\u00e9ria, mais qu\u2019elle est produite en plus petite quantit\u00e9 chez nous tous, et que les niveaux de prog\u00e9rine augmentent avec l\u2019\u00e2ge. Ind\u00e9pendamment, des recherches ant\u00e9rieures sur le raccourcissement et le dysfonctionnement des t\u00e9lom\u00e8res ont \u00e9t\u00e9 associ\u00e9es au vieillissement normal. Depuis 2003, avec la d\u00e9couverte de la mutation du g\u00e8ne de la prog\u00e9ria et de la prot\u00e9ine prog\u00e9rine qui cause la maladie, l\u2019un des principaux domaines de recherche s\u2019est concentr\u00e9 sur la compr\u00e9hension du lien entre la prog\u00e9ria et le vieillissement.<\/p>\n<p class=\"yiv314624100msonormal\">\u00ab L\u2019association entre ce ph\u00e9nom\u00e8ne de maladie rare et le vieillissement normal porte ses fruits de mani\u00e8re importante \u00bb, a d\u00e9clar\u00e9 le directeur du NIH, Francis S. Collins, docteur en m\u00e9decine et auteur principal de l\u2019\u00e9tude. \u00ab Cette \u00e9tude montre que l\u2019\u00e9tude de troubles g\u00e9n\u00e9tiques rares tels que la prog\u00e9ria permet d\u2019obtenir des informations biologiques pr\u00e9cieuses. Nous avons senti d\u00e8s le d\u00e9part que la prog\u00e9ria avait beaucoup \u00e0 nous apprendre sur le processus normal de vieillissement. \u00bb<\/p>\n<p class=\"yiv314624100msoplaintext\">Les scientifiques ont traditionnellement \u00e9tudi\u00e9 les t\u00e9lom\u00e8res et la prog\u00e9rine s\u00e9par\u00e9ment. Bien qu\u2019il reste encore beaucoup \u00e0 apprendre pour savoir si cette nouvelle connexion peut conduire \u00e0 un traitement pour les enfants atteints de prog\u00e9ria ou peut potentiellement \u00eatre appliqu\u00e9e \u00e0 l\u2019allongement de la dur\u00e9e de vie humaine, cette \u00e9tude fournit une preuve suppl\u00e9mentaire que la prog\u00e9rine, la prot\u00e9ine toxique d\u00e9couverte gr\u00e2ce \u00e0 la d\u00e9couverte de la mutation g\u00e9n\u00e9tique de la prog\u00e9ria, joue un r\u00f4le dans le processus normal de vieillissement.<\/p>\n<p class=\"yiv314624100msoplaintext justifyleft\">*<em>La prog\u00e9rine et le dysfonctionnement des t\u00e9lom\u00e8res collaborent pour d\u00e9clencher la s\u00e9nescence cellulaire dans les fibroblastes humains normaux<\/em>, Cao et al, <em>J Clin Invest <\/em>doi:10.1172\/JCI43578.<\/p>\n<p class=\"yiv314624100msoplaintext\"><a href=\"https:\/\/www.progeriaresearch.org\/fr\/assets\/files\/pdf\/psa_ads\/NIH%20Press%20Release.pdf\/\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/web.archive.org\/web\/20170216015614im_\/https:\/\/www.progeriaresearch.org\/assets\/images\/iconPDF.gif\" alt=\"\" width=\"34\" height=\"20\" \/>Cliquez ici<\/a> pour le texte int\u00e9gral du communiqu\u00e9 de presse du NIH.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.22&#8243;][et_pb_row _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.6.5&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;] The captivating connection between Progeria and aging continues to strengthen, as NIH researchers find link between telomeres and progerin. National Institutes of Health researchers have discovered a previously unknown link between Progeria and aging.\u00a0 The findings provide insights [&hellip;]<\/p>","protected":false},"author":1,"featured_media":2048,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p>[vc_custom_heading text=\"Groundbreaking Study on Progeria-Aging Link\" font_container=\"tag:h1|text_align:left\" use_theme_fonts=\"yes\"]<\/p><div id=\"secondary-header-content\"><p>The captivating connection between Progeria and aging continues to strengthen, as NIH researchers find link between telomeres and progerin.<\/p><\/div><p class=\"yiv314624100msonormal\"><a href=\"https:\/\/www.cbsnews.com\/news\/clues-about-how-we-age-found-in-genetic-disorder\/\"><img class=\"aligncenter size-full wp-image-2052\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/Capture.png\" alt=\"\" width=\"427\" height=\"279\" \/><\/a>National Institutes of Health researchers have discovered a previously unknown link between Progeria and aging.\u00a0 The findings provide insights about the relationship between the toxic, Progeria-causing protein known as <strong>progerin <\/strong>and <strong>telomeres<\/strong>, which protect the ends of DNA within cells until they wear away over time and the cells die.<\/p><p class=\"yiv314624100msonormal\">The study* appears in the June 13, 2011 early online edition of the Journal of Clinical Investigation. It concludes that in normal aging, short or dysfunctional telomeres stimulate cells to produce progerin, which is associated with age-related cell damage.<\/p>[caption id=\"attachment_2048\" align=\"aligncenter\" width=\"400\"]<img class=\"wp-image-2048 size-full\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg\" alt=\"\" width=\"400\" height=\"159\" \/> Progerin-expressing cells from normal individuals show signs of senescence. DNA in the nucleus is stained blue. Telomeres are seen as red dots.[\/caption]<p class=\"yiv314624100msonormal\">\"<strong>For the first time, we know that telomere shortening and dysfunction influences the production of progerin,\" says The Progeria Research Foundation Medical Director Leslie B. Gordon, MD, PhD. \"Thus these two processes, both of which influence cellular aging, are actually linked.\"<\/strong><\/p><p class=\"yiv314624100msonormal\">Prior research has shown that progerin is not only produced in children with Progeria, but that it is produced in smaller amounts in all of us, and progerin levels increase with aging. Independently, previous research on telomere shortening and dysfunction has been associated with normal aging. Since 2003, with the discovery of the Progeria gene mutation and the progerin protein that causes the disease, one of the key areas of research has focused on understanding whether and how Progeria and aging are linked.<\/p><p class=\"yiv314624100msonormal\">\"Connecting this rare disease phenomenon and normal aging is bearing fruit in an important way,\" said NIH Director Francis S. Collins, MD, PhD, a senior author of the paper. \"This study highlights that valuable biological insights are gained by studying rare genetic disorders such as Progeria. Our sense from the start was that Progeria had a lot to teach us about the normal aging process. \"<\/p><p class=\"yiv314624100msoplaintext\">Scientists have traditionally studied telomeres and progerin separately. While there is still much to learn about whether this new connection can lead to a cure for children with Progeria or potentially be applied to extending the human lifespan, this study provides further evidence that progerin, the toxic protein discovered through finding the gene mutation in Progeria, plays a role in the normal aging process.<\/p><p class=\"yiv314624100msoplaintext justifyleft\">*<em>Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts<\/em>, Cao et al, <em>J Clin Invest <\/em>doi:10.1172\/JCI43578.<\/p><p class=\"yiv314624100msoplaintext\"><a href=\"https:\/\/www.progeriaresearch.org\/assets\/files\/pdf\/psa_ads\/NIH%20Press%20Release.pdf\"><img src=\"https:\/\/web.archive.org\/web\/20170216015614im_\/https:\/\/www.progeriaresearch.org\/assets\/images\/iconPDF.gif\" alt=\"\" width=\"34\" height=\"20\" \/>Click here<\/a> for the full text of the NIH press release.<\/p>","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-2047","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Groundbreaking Study on Progeria-Aging Link - The Progeria Research Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/fr\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Groundbreaking Study on Progeria-Aging Link - The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.22&#8243;][et_pb_row _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.6.5&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;] The captivating connection between Progeria and aging continues to strengthen, as NIH researchers find link between telomeres and progerin. National Institutes of Health researchers have discovered a previously unknown link between Progeria and aging.\u00a0 The findings provide insights [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.progeriaresearch.org\/fr\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/\" \/>\n<meta property=\"og:site_name\" content=\"The Progeria Research Foundation\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ProgeriaResearch\/\" \/>\n<meta property=\"article:published_time\" content=\"2011-05-16T12:31:46+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-12-10T22:54:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"400\" \/>\n\t<meta property=\"og:image:height\" content=\"159\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"gravoc\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@Progeria\" \/>\n<meta name=\"twitter:site\" content=\"@Progeria\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"gravoc\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/\"},\"author\":{\"name\":\"gravoc\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/a3c935a81e92242c6a77ae0018542928\"},\"headline\":\"Groundbreaking Study on Progeria-Aging Link\",\"datePublished\":\"2011-05-16T12:31:46+00:00\",\"dateModified\":\"2020-12-10T22:54:48+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/\"},\"wordCount\":488,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg\",\"articleSection\":[\"News\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/\",\"name\":\"Groundbreaking Study on Progeria-Aging Link - The Progeria Research Foundation\",\"isPartOf\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg\",\"datePublished\":\"2011-05-16T12:31:46+00:00\",\"dateModified\":\"2020-12-10T22:54:48+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#primaryimage\",\"url\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg\",\"contentUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg\",\"width\":400,\"height\":159,\"caption\":\"\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.progeriaresearch.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Groundbreaking Study on Progeria-Aging Link\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#website\",\"url\":\"https:\/\/www.progeriaresearch.org\/ta\/\",\"name\":\"The Progeria Research Foundation\",\"description\":\"For the Children \u2665 For the Cure\",\"publisher\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.progeriaresearch.org\/ta\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\",\"name\":\"The Progeria Research Foundation\",\"url\":\"https:\/\/www.progeriaresearch.org\/ta\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png\",\"contentUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png\",\"width\":300,\"height\":86,\"caption\":\"The Progeria Research Foundation\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/ProgeriaResearch\/\",\"https:\/\/x.com\/Progeria\",\"https:\/\/www.instagram.com\/progeriaresearch\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/a3c935a81e92242c6a77ae0018542928\",\"name\":\"gravoc\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/cee2d206466fdbfc70635d168190f07f615d6e9c97c316eb6a88b5b563efdd7b?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/cee2d206466fdbfc70635d168190f07f615d6e9c97c316eb6a88b5b563efdd7b?s=96&d=mm&r=g\",\"caption\":\"gravoc\"},\"url\":\"https:\/\/www.progeriaresearch.org\/fr\/author\/gravoc\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Groundbreaking Study on Progeria-Aging Link - The Progeria Research Foundation","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.progeriaresearch.org\/fr\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/","og_locale":"fr_FR","og_type":"article","og_title":"Groundbreaking Study on Progeria-Aging Link - The Progeria Research Foundation","og_description":"[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.22&#8243;][et_pb_row _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.6.5&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;] The captivating connection between Progeria and aging continues to strengthen, as NIH researchers find link between telomeres and progerin. National Institutes of Health researchers have discovered a previously unknown link between Progeria and aging.\u00a0 The findings provide insights [&hellip;]","og_url":"https:\/\/www.progeriaresearch.org\/fr\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/","og_site_name":"The Progeria Research Foundation","article_publisher":"https:\/\/www.facebook.com\/ProgeriaResearch\/","article_published_time":"2011-05-16T12:31:46+00:00","article_modified_time":"2020-12-10T22:54:48+00:00","og_image":[{"width":400,"height":159,"url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg","type":"image\/jpeg"}],"author":"gravoc","twitter_card":"summary_large_image","twitter_creator":"@Progeria","twitter_site":"@Progeria","twitter_misc":{"Written by":"gravoc","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#article","isPartOf":{"@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/"},"author":{"name":"gravoc","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/a3c935a81e92242c6a77ae0018542928"},"headline":"Groundbreaking Study on Progeria-Aging Link","datePublished":"2011-05-16T12:31:46+00:00","dateModified":"2020-12-10T22:54:48+00:00","mainEntityOfPage":{"@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/"},"wordCount":488,"commentCount":0,"publisher":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#organization"},"image":{"@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#primaryimage"},"thumbnailUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg","articleSection":["News"],"inLanguage":"fr-FR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/","url":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/","name":"Groundbreaking Study on Progeria-Aging Link - The Progeria Research Foundation","isPartOf":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#primaryimage"},"image":{"@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#primaryimage"},"thumbnailUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg","datePublished":"2011-05-16T12:31:46+00:00","dateModified":"2020-12-10T22:54:48+00:00","breadcrumb":{"@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#primaryimage","url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg","contentUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/panel.jpg","width":400,"height":159,"caption":""},{"@type":"BreadcrumbList","@id":"https:\/\/www.progeriaresearch.org\/ur\/2011\/05\/16\/groundbreaking-study-on-progeria-aging-link\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.progeriaresearch.org\/"},{"@type":"ListItem","position":2,"name":"Groundbreaking Study on Progeria-Aging Link"}]},{"@type":"WebSite","@id":"https:\/\/www.progeriaresearch.org\/ta\/#website","url":"https:\/\/www.progeriaresearch.org\/ta\/","name":"La Fondation de recherche sur la prog\u00e9ria","description":"Pour les enfants \u2665 Pour la gu\u00e9rison","publisher":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.progeriaresearch.org\/ta\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/www.progeriaresearch.org\/ta\/#organization","name":"La Fondation de recherche sur la prog\u00e9ria","url":"https:\/\/www.progeriaresearch.org\/ta\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/","url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png","contentUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png","width":300,"height":86,"caption":"The Progeria Research Foundation"},"image":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ProgeriaResearch\/","https:\/\/x.com\/Progeria","https:\/\/www.instagram.com\/progeriaresearch\/"]},{"@type":"Person","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/a3c935a81e92242c6a77ae0018542928","name":"gravoc","image":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/cee2d206466fdbfc70635d168190f07f615d6e9c97c316eb6a88b5b563efdd7b?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/cee2d206466fdbfc70635d168190f07f615d6e9c97c316eb6a88b5b563efdd7b?s=96&d=mm&r=g","caption":"gravoc"},"url":"https:\/\/www.progeriaresearch.org\/fr\/author\/gravoc\/"}]}},"_links":{"self":[{"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/posts\/2047","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/comments?post=2047"}],"version-history":[{"count":0,"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/posts\/2047\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/media\/2048"}],"wp:attachment":[{"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/media?parent=2047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/categories?post=2047"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/fr\/wp-json\/wp\/v2\/tags?post=2047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}