{"id":1477,"date":"2017-04-19T12:43:11","date_gmt":"2017-04-19T12:43:11","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?page_id=1477"},"modified":"2023-09-21T11:28:47","modified_gmt":"2023-09-21T15:28:47","slug":"about-progeria","status":"publish","type":"page","link":"https:\/\/www.progeriaresearch.org\/he\/about-progeria\/","title":{"rendered":"\u05e2\u05dc \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4"},"content":{"rendered":"

[et_pb_section fb_built=\u201d1\u2033 fullwidth=\u201don\u201d disabled_on=\u201doff|off|off\u201d _builder_version=\u201d4.16\u2033 border_width_bottom=\u201d55px\u201d border_color_bottom=\u201d#29327a\u201d global_head_full_info=\u201dglobal_head_full_info=\u201d _builder_version=\u201d4.16\u2033 title_font_size=\u201d55\u2033 background_color=\u201d#29327a\u201d background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/About-Header.jpg\u201d backgroundle_position=\u201d custom_padding=\u201d9vw||9vw||true\u201d custom_padding_tablet=\u201d\u201d custom_padding_phone=\u201d|56px||\u201d custom_padding_last_edited=\u201d\u05e2\u05dc|\u05e9\u05d5\u05dc\u05d7\u05df \u05d4\u05e2\u05d1\u05d5\u05d3\u05d4\u201d title_font_size_tablet=\u201d45px\u201d title_font_size_phone=\u201d40px\u201d title_font_size_last_edited=\u201d\u05e2\u05dc|\u05d8\u05dc\u05e4\u05d5\u05df\u201d z_index_tablet=\u201d500\u2033 custom_css_1_ground-1_position:=\u201d centre_background-100% global_colors_info="{}"]<\/p>\n

\u05e2\u05dc \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4<\/h1>\n

[\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=\u201d1\u2033 use_custom_gutter=\u201don\u201d gutter_width=\u201d1\u2033 specialty=\u201don\u201d padding_left_1=\u201d35px\u201d padding_left_2=\u201d35px\u201d padding_left_2==\u201d35p_|x\u201d0ablet padding_2_|x\u201d0 padding_2_phone=\u201d|||0px\u201d padding_2_last_edited=\u201don|desktop\u201d module_class_1=\u201dsidebar-secondary-nav\u201d module_class=\u201dhandprint-bg\u201d _builder_version=\u201d4.16\u2033 background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/blue-handprint-only.png\u201d parallax=\u201don\u201d parallax_method=\u201doff\u201d inner_width=\u201d100%\u201d inner_max_width=\u201d100% \u201d custom_padding=\u201d0|0px|54px|0px|false|false\u201d z_index_tablet=\u201d500\u2033 border_width_top=\u201d10px\u201d border_color_top=\u201d#8fd2ed\u201d use_custom_width=\u201don\u201d width_unit=\u201doff1\u201d width_unit=\u201doff1\u201d TP3\u201d1\u201d global_colors_info=\u201d{}\u201d][et_pb_column type=\u201d1_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_sidebar area=\u201det_pb_widget_area_18\u2033 disabled_on=\u201don|on|off\u201d module_class=\u201dsubpage-sidebars\u201d _builder_version=\u201d4.16\u2033=\u201dfaade_style\u201d 500 \u05d0\u05d9\u05e0\u05e5' border_width_right="5px" global_colors_info="{}"]<\/p>\n

[\/et_pb_sidebar][\/et_pb_column][et_pb_column type=\u201d3_4\u2033 specialty_columns=\u201d3\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_row_inner custom_padding_last_edited=\u201don|phone\u201d _builder_version=\u201d4.16\u2033 custom_padding=\u201d39.4375px|35px|35px||false|false custom_padding_tablet=\u201d|35px||35px||true\u201d custom_padding_phone=\u201d\u201d animation_direction=\u201dtop\u201d global_colors_info=\u201d{}\u201d][et_pb_column_inner saved_specialty_column_type=\u20333_4\u2033 _builder_padding=\u201d|customer_6. global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_text _builder_version=\u201d4.19.5\u2033 background_size=\u201dinitial\u201d background_position=\u201dtop_left\u201d background_repeat=\u201drepeat\u201d global_colors_info=\u201d{}\u201d]<\/p>\n

\"\"\u05ea\u05e1\u05de\u05d5\u05e0\u05ea \u05d4\u05d0\u05e6'\u05d9\u05e0\u05e1\u05d5\u05df-\u05d2\u05d9\u05dc\u05e4\u05d5\u05e8\u05d3 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 ("\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4", \u05d0\u05d5 "HGPS") \u05d4\u05d9\u05d0 \u05de\u05e6\u05d1 \u05d2\u05e0\u05d8\u05d9 \u05e0\u05d3\u05d9\u05e8 \u05d5\u05e7\u05d8\u05dc\u05e0\u05d9 \u05d4\u05de\u05d0\u05d5\u05e4\u05d9\u05d9\u05df \u05d1\u05d4\u05d5\u05e4\u05e2\u05d4 \u05e9\u05dc \u05d4\u05d6\u05d3\u05e7\u05e0\u05d5\u05ea \u05de\u05d5\u05d0\u05e6\u05ea \u05d1\u05d9\u05dc\u05d3\u05d9\u05dd. \u05e9\u05de\u05d5 \u05e0\u05d2\u05d6\u05e8 \u05de\u05d9\u05d5\u05d5\u05e0\u05d9\u05ea \u05d5\u05e4\u05d9\u05e8\u05d5\u05e9\u05d5 "\u05d6\u05e7\u05df \u05d1\u05d8\u05e8\u05dd \u05e2\u05ea". \u05d1\u05e2\u05d5\u05d3 \u05e9\u05d9\u05e9\u05e0\u05df \u05e6\u05d5\u05e8\u05d5\u05ea \u05e9\u05d5\u05e0\u05d5\u05ea \u05e9\u05dc \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4*, \u05d4\u05e1\u05d5\u05d2 \u05d4\u05e7\u05dc\u05d0\u05e1\u05d9 \u05d4\u05d5\u05d0 \u05ea\u05e1\u05de\u05d5\u05e0\u05ea \u05d4\u05d0\u05e6'\u05d9\u05e0\u05e1\u05d5\u05df-\u05d2\u05d9\u05dc\u05e4\u05d5\u05e8\u05d3 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4, \u05e9\u05e0\u05e7\u05e8\u05d0\u05d4 \u05e2\u05dc \u05e9\u05dd \u05d4\u05e8\u05d5\u05e4\u05d0\u05d9\u05dd \u05e9\u05ea\u05d9\u05d0\u05e8\u05d5 \u05d0\u05d5\u05ea\u05d4 \u05dc\u05e8\u05d0\u05e9\u05d5\u05e0\u05d4 \u05d1\u05d0\u05e0\u05d2\u05dc\u05d9\u05d4; \u05d1\u05e9\u05e0\u05ea 1886 \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d3"\u05e8 \u05d2'\u05d5\u05e0\u05ea\u05df \u05d4\u05d0\u05e6'\u05d9\u05e0\u05e1\u05d5\u05df \u05d5\u05d1\u05e9\u05e0\u05ea 1897 \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d3"\u05e8 \u05d4\u05d9\u05d9\u05e1\u05d8\u05d9\u05e0\u05d2\u05e1 \u05d2\u05d9\u05dc\u05e4\u05d5\u05e8\u05d3.<\/p>\n

HGPS \u05e0\u05d2\u05e8\u05de\u05ea \u05e2\u05dc \u05d9\u05d3\u05d9 \u05de\u05d5\u05d8\u05e6\u05d9\u05d4 \u05d1\u05d2\u05df \u05d4\u05e0\u05e7\u05e8\u05d0\u05ea LMNA (\u05de\u05d1\u05d5\u05d8\u05d0, lamin - a). \u05d4\u05d2\u05df LMNA \u05de\u05d9\u05d9\u05e6\u05e8 \u05d0\u05ea \u05d4\u05d7\u05dc\u05d1\u05d5\u05df Lamin A, \u05e9\u05d4\u05d5\u05d0 \u05d4\u05e4\u05d9\u05d2\u05d5\u05dd \u05d4\u05de\u05d1\u05e0\u05d9 \u05e9\u05de\u05d7\u05d6\u05d9\u05e7 \u05d0\u05ea \u05d2\u05e8\u05e2\u05d9\u05df \u05d4\u05ea\u05d0 \u05d9\u05d7\u05d3. \u05d7\u05d5\u05e7\u05e8\u05d9\u05dd \u05de\u05d0\u05de\u05d9\u05e0\u05d9\u05dd \u05db\u05e2\u05ea \u05e9\u05d7\u05dc\u05d1\u05d5\u05df Lamin A \u05d4\u05e4\u05d2\u05d5\u05dd \u05d4\u05d5\u05e4\u05da \u05d0\u05ea \u05d4\u05d2\u05e8\u05e2\u05d9\u05df \u05dc\u05d1\u05dc\u05ea\u05d9 \u05d9\u05e6\u05d9\u05d1. \u05e0\u05e8\u05d0\u05d4 \u05e9\u05d7\u05d5\u05e1\u05e8 \u05d4\u05d9\u05e6\u05d9\u05d1\u05d5\u05ea \u05d4\u05ea\u05d0\u05d9\u05ea \u05de\u05d5\u05d1\u05d9\u05dc\u05d4 \u05dc\u05ea\u05d4\u05dc\u05d9\u05da \u05e9\u05dc \u05d4\u05d6\u05d3\u05e7\u05e0\u05d5\u05ea \u05de\u05d5\u05e7\u05d3\u05de\u05ea \u05d1\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4.<\/p>\n

\u05dc\u05de\u05e8\u05d5\u05ea \u05e9\u05d4\u05dd \u05e0\u05d5\u05dc\u05d3\u05d9\u05dd \u05d1\u05de\u05e8\u05d0\u05d4 \u05d1\u05e8\u05d9\u05d0, \u05d9\u05dc\u05d3\u05d9\u05dd \u05e2\u05dd \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05de\u05ea\u05d7\u05d9\u05dc\u05d9\u05dd \u05dc\u05d4\u05e6\u05d9\u05d2 \u05de\u05d0\u05e4\u05d9\u05d9\u05e0\u05d9\u05dd \u05e8\u05d1\u05d9\u05dd \u05e9\u05dc \u05d4\u05d6\u05d3\u05e7\u05e0\u05d5\u05ea \u05de\u05d5\u05d0\u05e6\u05ea \u05d1\u05e9\u05e0\u05ea\u05d9\u05d9\u05dd \u05d4\u05e8\u05d0\u05e9\u05d5\u05e0\u05d5\u05ea \u05dc\u05d7\u05d9\u05d9\u05d4\u05dd. \u05e1\u05d9\u05de\u05e0\u05d9 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05db\u05d5\u05dc\u05dc\u05d9\u05dd \u05db\u05e9\u05dc \u05d1\u05d2\u05d3\u05d9\u05dc\u05d4, \u05d0\u05d5\u05d1\u05d3\u05df \u05e9\u05d5\u05de\u05df \u05d5\u05e9\u05d9\u05e2\u05e8 \u05d1\u05d2\u05d5\u05e3, \u05e2\u05d5\u05e8 \u05de\u05d1\u05d5\u05d2\u05e8 \u05dc\u05de\u05e8\u05d0\u05d4, \u05e0\u05d5\u05e7\u05e9\u05d5\u05ea \u05e9\u05dc \u05de\u05e4\u05e8\u05e7\u05d9\u05dd, \u05e4\u05e8\u05d9\u05e7\u05ea \u05de\u05e4\u05e8\u05e7 \u05d4\u05d9\u05e8\u05da, \u05d8\u05e8\u05e9\u05ea \u05e2\u05d5\u05e8\u05e7\u05d9\u05dd \u05db\u05dc\u05dc\u05d9\u05ea, \u05de\u05d7\u05dc\u05d5\u05ea \u05dc\u05d1 \u05d5\u05db\u05dc\u05d9 \u05d3\u05dd \u05d5\u05e9\u05d1\u05e5 \u05de\u05d5\u05d7\u05d9. \u05dc\u05d9\u05dc\u05d3\u05d9\u05dd \u05d9\u05e9 \u05de\u05e8\u05d0\u05d4 \u05d3\u05d5\u05de\u05d4 \u05dc\u05d4\u05e4\u05dc\u05d9\u05d0, \u05dc\u05de\u05e8\u05d5\u05ea \u05e8\u05e7\u05e2 \u05d0\u05ea\u05e0\u05d9 \u05e9\u05d5\u05e0\u05d4. \u05dc\u05dc\u05d0 \u05d8\u05d9\u05e4\u05d5\u05dc, \u05d9\u05dc\u05d3\u05d9\u05dd \u05e2\u05dd \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05de\u05ea\u05d9\u05dd \u05de\u05d8\u05e8\u05e9\u05ea \u05e2\u05d5\u05e8\u05e7\u05d9\u05dd (\u05de\u05d7\u05dc\u05ea \u05dc\u05d1) \u05d1\u05d2\u05d9\u05dc \u05de\u05de\u05d5\u05e6\u05e2 \u05e9\u05dc 14.5 \u05e9\u05e0\u05d9\u05dd.<\/p>\n

* \u05ea\u05e1\u05de\u05d5\u05e0\u05d5\u05ea \u05e4\u05e8\u05d5\u05d2\u05e8\u05d5\u05d0\u05d9\u05d3 \u05d0\u05d7\u05e8\u05d5\u05ea \u05db\u05d5\u05dc\u05dc\u05d5\u05ea \u05d0\u05ea \u05ea\u05e1\u05de\u05d5\u05e0\u05ea \u05d5\u05e8\u05e0\u05e8, \u05d4\u05d9\u05d3\u05d5\u05e2\u05d4 \u05d2\u05dd \u05d1\u05e9\u05dd "\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05dc\u05de\u05d1\u05d5\u05d2\u05e8\u05d9\u05dd" \u05d0\u05e9\u05e8 \u05dc\u05d0 \u05d4\u05d5\u05e4\u05d9\u05e2\u05d4 \u05e2\u05d3 \u05e1\u05d5\u05e3 \u05e9\u05e0\u05d5\u05ea \u05d4\u05e2\u05e9\u05e8\u05d4, \u05e2\u05dd \u05ea\u05d5\u05d7\u05dc\u05ea \u05d7\u05d9\u05d9\u05dd \u05e2\u05d3 \u05e9\u05e0\u05d5\u05ea \u05d4-40 \u05d5\u05d4-50.<\/p>\n

[\/et_pb_text][et_pb_button button_url=\u201dhttps:\/\/www.progeriaresearch.org\/scientific-publications\/\u201d button_text=\u201dView Scientific Publications\u201d _builder_version=\u201d4.16\u2033 background_layout=\u201ddark\u201d custom_margin=\u201d20px||\u201d global_colors_info="{}"]<\/p>\n

[\/et_pb_button][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=\u201d1\u2033 module_class=\u201dfooter\u201d _builder_version=\u201d4.21.2\u201d7 TPacolor=\u201d4.21.2\u201d7 custom_margin="-2px|||||" custom_padding=\u201d0|0px|0|0px|false|false\u201d z_index_tablet=\u201d500\u2033 border_width_top=\u201d12px\u201d border_color_top=\u201d#00b2e2\u2033 global_module=\u201d133\u2033 locked=\u201doff\u201d\u200e_\u201d_b_colors column_structure=\u201d1_4,1_4,1_2\u2033 make_equal=\u201don\u201d module_class=\u201d et_pb_row_fullwidth\u201d _builder_version=\u201d4.16\u2033 width=\u201d89%\u201d width_tablet=\u201d80%\u201d width_phone=\u201d_\u201d width_phone=\u201d_\u201d width_phone=\u201d_\u201d max_width=\u201d89%\u201d max_width_tablet=\u201d80%\u201d max_width_phone=\u201d\u201d max_width_last_edited=\u201don|desktop\u201d z_index_tablet=\u201d500\u2033 make_fullwidth=\u201don\u201d width_unit=\u201d0_percent\u201d custom_\u201dT_0_0%\u201d global_colors_info=\u201d{}\u201d][et_pb_column type=\u201d1_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_cta button_url=\u201dhttps:\/\/www.progeriaresearch.org\/newsletter-signup\/\u201d button_text=\u201d\u05d4\u05d9\u05e8\u05e9\u05dd \u05e2\u05db\u05e9\u05d9\u05d5\u201d admin_label=\u201d\u05d4\u05d9\u05e8\u05e9\u05dd \u05dc\u05e0\u05d9\u05d5\u05d6\u05dc\u05d8\u05e8\u201d module_class ="sign-btn" _builder_version="4.16" header_font_size=\u201d25px\u201d background_color=\u201d#29327a\u201d animation_style=\u201dslide\u201d animation_direction=\u201dleft\u201d animation_intensity_slide=\u201d25%\u201d header_font_size_tablet=\u201d\u201d header_font_size_phone\u201d=\u201d header_font_size_last_edited=\u201don|desktop\u201d z_index_tablet=\u201d500\u2033 border_radii=\u201don|25px|25px|25px|25px\u201d global_colors_info=\u201d{}\u201d button_bg_color__hover_enabled=\u201don\u201d button_border_color__hover_enabled="on"]<\/p>\n

\u05d4\u05d9\u05e8\u05e9\u05dd<\/h2>\n

\u05e2\u05d1\u05d5\u05e8 \u05e9\u05dc\u05e0\u05d5<\/h2>\n

\u05e0\u05d9\u05d5\u05d6\u05dc\u05d8\u05e8!<\/h2>\n

[\/et_pb_cta][\/et_pb_column][et_pb_column type=\u201d1_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_cta button_url=\u201dhttps:\/\/progeriaresearch.donorsupport.co\/-\/XZHJVWZR\u201d button_text=\u201d\u05ea\u05e8\u05d5\u05dd \u05e2\u05db\u05e9\u05d9\u05d5\u201d admin_label=\u201d\u05d1\u05d9\u05d7\u05d3, \u05e0\u05de\u05e6\u05d0 \u05d0\u05ea \u05d4\u05ea\u05e8\u05d5\u05e4\u05d4! \u201d module_class=\u201dsign-btn\u201d _builder_version=\u201d4.16\u2033 header_font_size=\u201d25px\u201d background_color=\u201d#29327a\u201d animation_style=\u201dslide\u201d animation_direction=\u201dleft\u201d animation_intensity_slide=\u201d251_TP327a\u201dheadertablets\u201d header_font_size_phone=\u201d30px\u201d header_font_size_last_edited=\u201don|desktop\u201d body_font_size_tablet=\u201d\u201d body_font_size_phone=\u201d\u201d body_font_size_last_edited=\u201don|desktop\u201d z_index_tablet=\u201d500\u2033 border_radii=\u201don|25px|25px|25px|25px\u201d global_colors_info=\u201d{}\u201d button_bg_color__hover_enabled=\u201don\u201d button_bg_color__hover=\u201d#8fd2ed\u201d button_border_color__hover_enabled=\u201don\u201d]<\/p>\n

\u05d1\u05d9\u05d7\u05d3, \u05d0\u05e0\u05d7\u05e0\u05d5<\/h2>\n

\u05e8\u05b8\u05e6\u05d5\u05b9\u05df<\/em><\/h2>\n

\u05dc\u05de\u05e6\u05d5\u05d0 \u05d0\u05ea \u05d4\u05ea\u05e8\u05d5\u05e4\u05d4!<\/h2>\n

[\/et_pb_cta][\/et_pb_column][et_pb_column type=\u201d1_2\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/06\/2023-footer-strip-5.png\u201d title_text ="2023 \u05e4\u05e1 \u05ea\u05d7\u05ea\u05d5\u05df 5 \u05d0\u05d9\u05e0\u05e5' _builder_version=\u201d4.21.0\u2033 _module_preset=\u201ddefault\u201d custom_margin=\u201d35px||||false|false\u201d global_colors_info=\u201d{}\u201d][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"

[et_pb_section fb_built=\u201d1\u2033 fullwidth=\u201don\u201d disabled_on=\u201doff|off|off\u201d _builder_version=\u201d4.16\u2033 border_width_bottom=\u201d55px\u201d border_color_bottom=\u201d#29327a\u201d global_head_full_info=\u201dglobal_head_full_info=\u201d _builder_version=\u201d4.16\u2033 title_font_size=\u201d55\u2033 background_color=\u201d#29327a\u201d background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/About-Header.jpg\u201d backgroundle_position=\u201d custom_padding=\u201d9vw||9vw||true\u201d custom_padding_tablet=\u201d\u201d custom_padding_phone=\u201d|56px||\u201d custom_padding_last_edited=\u201d\u05e2\u05dc|\u05e9\u05d5\u05dc\u05d7\u05df \u05d4\u05e2\u05d1\u05d5\u05d3\u05d4\u201d title_font_size_tablet=\u201d45px\u201d title_font_size_phone=\u201d40px\u201d title_font_size_last_edited=\u201d\u05e2\u05dc|\u05d8\u05dc\u05e4\u05d5\u05df\u201d z_index_tablet=\u201d500\u2033 custom_css_1_ground-1_position:=\u201d centre_background-100% global_colors_info=\u201d{}\u201d] \u05d0\u05d5\u05d3\u05d5\u05ea Progeria [\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=\u201d1\u2033 use_custom_gutter=\u201don\u201d gutter_width=\u201d1\u2033 specialty=\u201don\u201d padding_left_2=\u201d3leftx\u201d padding_left_2=\u201d3leftx\u201d_5pleftx\u201d padding padding_2_tablet=\u201d|||0px\u201d padding_2_phone=\u201d|||0px\u201d padding_2_last_edited=\u201don|desktop\u201d module_class_1=\u201dsidebar-secondary-nav\u201d module_class=\u201dhandprint-bg\u201d _builder_version=\u201d4.16\u2033 background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/blue-handprint-only.png\u201d parallax=\u201don\u201d parallax_method=\u201doff\u201d inner_width=\u201d100%\u201d inner_max_width=\u201d100% \u201d custom_padding=\u201d0|0px|54px|0px|false|false\u201d z_index_tablet=\u201d500\u2033 border_width_top=\u201d10px\u201d border_color_top=\u201d#8fd2ed\u201d use_custom_width=\u201don\u201d width_unit=\u201doff1\u201d width_unit=\u201doff1\u201d TP3\u201d1\u201d global_colors_info=\u201d{}\u201d][et_pb_column type=\u201d1_4\u2033 [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"\t\t\t\t[vc_row][vc_column][vc_custom_heading text=\"About Progeria\" font_container=\"tag:h1|text_align:center\" use_theme_fonts=\"yes\"][vc_column_text]\"\"Hutchinson-Gilford Progeria Syndrome (\"Progeria\", or \"HGPS\") is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Its name is derived from the Greek and means \"prematurely old.\" While there are different forms of Progeria*, the classic type is Hutchinson-Gilford Progeria Syndrome, which was named after the doctors who first described it in England; in 1886 by Dr. Jonathan Hutchinson and in 1897 by Dr. Hastings Gilford.\r\n\r\nHGPS is caused by a mutation in the gene called LMNA (pronounced, lamin - a). The LMNA gene produces the Lamin A protein, which is the structural scaffolding that holds the nucleus of a cell together. Researchers now believe that the defective Lamin A protein makes the nucleus unstable. That cellular instability appears to lead to the process of premature aging in Progeria.\r\n\r\nAlthough they are born looking healthy, children with Progeria begin to display many characteristics of accelerated aging within the first two years of life.\u00a0Progeria signs include growth failure, loss of body fat and hair, aged-looking skin, stiffness of joints, hip dislocation, generalized atherosclerosis, cardiovascular (heart) disease and stroke. The children have a remarkably similar appearance, despite differing ethnic backgrounds. Children with Progeria die of atherosclerosis (heart disease) at an average age of fourteen years.\r\n\r\n* Other progeroid syndromes include Werner's syndrome, also known as \"adult progeria\" which does not have an onset until the late teen years, with a life span into the 40's and 50's.\r\n\r\nClick here<\/a> for\u00a0information on\u00a0scientific articles on Progeria.[\/vc_column_text][\/vc_column][\/vc_row]\t\t","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1477","page","type-page","status-publish","hentry"],"yoast_head":"\nAbout Progeria | The Progeria Research Foundation<\/title>\n<meta name=\"description\" content=\"Progeria is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Click to learn more about progeria here.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/he\/about-progeria\/\" \/>\n<meta property=\"og:locale\" content=\"he_IL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"About Progeria | The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"Progeria is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Click to learn more about progeria here.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.progeriaresearch.org\/he\/about-progeria\/\" \/>\n<meta property=\"og:site_name\" content=\"The Progeria Research Foundation\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ProgeriaResearch\/\" \/>\n<meta property=\"article:modified_time\" content=\"2023-09-21T15:28:47+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/04\/lindsay-Jul08-crpd.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Progeria\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 \u05d3\u05e7\u05d5\u05ea\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.progeriaresearch.org\/about-progeria\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/about-progeria\/\",\"name\":\"About Progeria | The Progeria Research Foundation\",\"isPartOf\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/about-progeria\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/about-progeria\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/04\/lindsay-Jul08-crpd.jpg\",\"datePublished\":\"2017-04-19T12:43:11+00:00\",\"dateModified\":\"2023-09-21T15:28:47+00:00\",\"description\":\"Progeria is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Click to learn more about progeria here.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/about-progeria\/#breadcrumb\"},\"inLanguage\":\"he-IL\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.progeriaresearch.org\/about-progeria\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"he-IL\",\"@id\":\"https:\/\/www.progeriaresearch.org\/about-progeria\/#primaryimage\",\"url\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/04\/lindsay-Jul08-crpd.jpg\",\"contentUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/04\/lindsay-Jul08-crpd.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.progeriaresearch.org\/about-progeria\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.progeriaresearch.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"About Progeria\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#website\",\"url\":\"https:\/\/www.progeriaresearch.org\/ta\/\",\"name\":\"The Progeria Research Foundation\",\"description\":\"For the Children \u2665 For the Cure\",\"publisher\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.progeriaresearch.org\/ta\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"he-IL\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\",\"name\":\"The Progeria Research Foundation\",\"url\":\"https:\/\/www.progeriaresearch.org\/ta\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"he-IL\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png\",\"contentUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png\",\"width\":300,\"height\":86,\"caption\":\"The Progeria Research Foundation\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/ProgeriaResearch\/\",\"https:\/\/x.com\/Progeria\",\"https:\/\/www.instagram.com\/progeriaresearch\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"About Progeria | The Progeria Research Foundation","description":"Progeria is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Click to learn more about progeria here.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.progeriaresearch.org\/he\/about-progeria\/","og_locale":"he_IL","og_type":"article","og_title":"About Progeria | The Progeria Research Foundation","og_description":"Progeria is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Click to learn more about progeria here.","og_url":"https:\/\/www.progeriaresearch.org\/he\/about-progeria\/","og_site_name":"The Progeria Research Foundation","article_publisher":"https:\/\/www.facebook.com\/ProgeriaResearch\/","article_modified_time":"2023-09-21T15:28:47+00:00","og_image":[{"url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/04\/lindsay-Jul08-crpd.jpg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_site":"@Progeria","twitter_misc":{"Est. reading time":"3 \u05d3\u05e7\u05d5\u05ea"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.progeriaresearch.org\/about-progeria\/","url":"https:\/\/www.progeriaresearch.org\/about-progeria\/","name":"About Progeria | The Progeria Research Foundation","isPartOf":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.progeriaresearch.org\/about-progeria\/#primaryimage"},"image":{"@id":"https:\/\/www.progeriaresearch.org\/about-progeria\/#primaryimage"},"thumbnailUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/04\/lindsay-Jul08-crpd.jpg","datePublished":"2017-04-19T12:43:11+00:00","dateModified":"2023-09-21T15:28:47+00:00","description":"Progeria is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Click to learn more about progeria here.","breadcrumb":{"@id":"https:\/\/www.progeriaresearch.org\/about-progeria\/#breadcrumb"},"inLanguage":"he-IL","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.progeriaresearch.org\/about-progeria\/"]}]},{"@type":"ImageObject","inLanguage":"he-IL","@id":"https:\/\/www.progeriaresearch.org\/about-progeria\/#primaryimage","url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/04\/lindsay-Jul08-crpd.jpg","contentUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/04\/lindsay-Jul08-crpd.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.progeriaresearch.org\/about-progeria\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.progeriaresearch.org\/"},{"@type":"ListItem","position":2,"name":"About Progeria"}]},{"@type":"WebSite","@id":"https:\/\/www.progeriaresearch.org\/ta\/#website","url":"https:\/\/www.progeriaresearch.org\/ta\/","name":"\u05e7\u05e8\u05df \u05d4\u05de\u05d7\u05e7\u05e8 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4","description":"\u05dc\u05d9\u05dc\u05d3\u05d9\u05dd \u2665 \u05dc\u05e8\u05d9\u05e4\u05d5\u05d9","publisher":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.progeriaresearch.org\/ta\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"he-IL"},{"@type":"Organization","@id":"https:\/\/www.progeriaresearch.org\/ta\/#organization","name":"\u05e7\u05e8\u05df \u05d4\u05de\u05d7\u05e7\u05e8 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4","url":"https:\/\/www.progeriaresearch.org\/ta\/","logo":{"@type":"ImageObject","inLanguage":"he-IL","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/","url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png","contentUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png","width":300,"height":86,"caption":"The Progeria Research Foundation"},"image":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ProgeriaResearch\/","https:\/\/x.com\/Progeria","https:\/\/www.instagram.com\/progeriaresearch\/"]}]}},"_links":{"self":[{"href":"https:\/\/www.progeriaresearch.org\/he\/wp-json\/wp\/v2\/pages\/1477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.progeriaresearch.org\/he\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.progeriaresearch.org\/he\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/he\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/he\/wp-json\/wp\/v2\/comments?post=1477"}],"version-history":[{"count":0,"href":"https:\/\/www.progeriaresearch.org\/he\/wp-json\/wp\/v2\/pages\/1477\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.progeriaresearch.org\/he\/wp-json\/wp\/v2\/media?parent=1477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}