{"id":12401,"date":"2021-03-11T21:08:40","date_gmt":"2021-03-12T02:08:40","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=12401"},"modified":"2022-11-14T17:12:14","modified_gmt":"2022-11-14T22:12:14","slug":"exciting-breakthroughs-in-rna-therapeutics-for-progeria","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/he\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/","title":{"rendered":"\u05e4\u05e8\u05d9\u05e6\u05d5\u05ea \u05d3\u05e8\u05da \u05de\u05e8\u05d2\u05e9\u05d5\u05ea \u05d1-RNA Therapeutics for Progeria!"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_row admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.18.1″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

\"\"<\/p>\n

\u05d0\u05e0\u05d5 \u05e0\u05e8\u05d2\u05e9\u05d9\u05dd \u05dc\u05d7\u05dc\u05d5\u05e7 \u05d0\u05ea \u05d4\u05ea\u05d5\u05e6\u05d0\u05d5\u05ea \u05de \u05e9\u05e0\u05d9 \u05de\u05d7\u05e7\u05e8\u05d9\u05dd \u05e4\u05d5\u05e8\u05e6\u05d9 \u05d3\u05e8\u05da \u05de\u05e8\u05d2\u05e9\u05d9\u05dd \u05e2\u05dc \u05d4\u05e9\u05d9\u05de\u05d5\u05e9 \u05d1\u05ea\u05e8\u05d5\u05e4\u05d5\u05ea RNA<\/strong> \u05d1\u05de\u05d7\u05e7\u05e8 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4. \u05e9\u05e0\u05d9 \u05d4\u05de\u05d7\u05e7\u05e8\u05d9\u05dd \u05de\u05d5\u05de\u05e0\u05d5 \u05e2\u05dc \u05d9\u05d3\u05d9 The Progeria Research Foundation (PRF) \u05d5\u05e0\u05db\u05ea\u05d1\u05d5 \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d4\u05de\u05e0\u05d4\u05dc\u05ea \u05d4\u05e8\u05e4\u05d5\u05d0\u05d9\u05ea \u05e9\u05dc PRF, \u05d3"\u05e8 \u05dc\u05e1\u05dc\u05d9 \u05d2\u05d5\u05e8\u05d3\u05d5\u05df.<\/p>\n

\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df \u05d4\u05d5\u05d0 \u05d4\u05d7\u05dc\u05d1\u05d5\u05df \u05d4\u05d2\u05d5\u05e8\u05dd \u05dc\u05de\u05d7\u05dc\u05d4 \u05d1\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4. \u05d8\u05d9\u05e4\u05d5\u05dc\u05d9 \u05d4-RNA \u05de\u05e4\u05e8\u05d9\u05e2\u05d9\u05dd \u05dc\u05d9\u05db\u05d5\u05dc\u05ea \u05d4\u05d2\u05d5\u05e3 \u05dc\u05d9\u05d9\u05e6\u05e8 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df, \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d7\u05e1\u05d9\u05de\u05ea \u05d9\u05d9\u05e6\u05d5\u05e8\u05d5 \u05d1\u05e8\u05de\u05ea \u05d4-RNA. \u05d6\u05d4 \u05d0\u05d5\u05de\u05e8 \u05e9 \u05d4\u05d8\u05d9\u05e4\u05d5\u05dc \u05e1\u05e4\u05e6\u05d9\u05e4\u05d9 \u05d9\u05d5\u05ea\u05e8 \u05de\u05e8\u05d5\u05d1 \u05d4\u05d8\u05d9\u05e4\u05d5\u05dc\u05d9\u05dd<\/strong> \u05e9\u05de\u05db\u05d5\u05d5\u05df \u05dc\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df \u05d1\u05e8\u05de\u05ea \u05d4\u05d7\u05dc\u05d1\u05d5\u05df.<\/p>\n

\u05dc\u05de\u05e8\u05d5\u05ea \u05e9\u05db\u05dc \u05de\u05d7\u05e7\u05e8 \u05d4\u05e9\u05ea\u05de\u05e9 \u05d1\u05de\u05e2\u05e8\u05db\u05ea \u05e9\u05d5\u05e0\u05d4 \u05dc\u05de\u05ea\u05df \u05ea\u05e8\u05d5\u05e4\u05d5\u05ea, \u05e9\u05e0\u05d9 \u05d4\u05de\u05d7\u05e7\u05e8\u05d9\u05dd \u05db\u05d5\u05d5\u05e0\u05d5 \u05dc\u05d0\u05d5\u05ea\u05d4 \u05d0\u05e1\u05d8\u05e8\u05d8\u05d2\u05d9\u05d9\u05ea \u05d8\u05d9\u05e4\u05d5\u05dc \u05d1\u05e1\u05d9\u05e1\u05d9\u05ea, \u05ea\u05d5\u05da \u05e2\u05d9\u05db\u05d5\u05d1 \u05d9\u05d9\u05e6\u05d5\u05e8 \u05e9\u05dc RNA \u05d4\u05de\u05e7\u05d5\u05d3\u05d3 \u05dc\u05d7\u05dc\u05d1\u05d5\u05df \u05d4\u05d7\u05e8\u05d9\u05d2, \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df. \u05e9\u05e0\u05d9\u05d4\u05dd \u05d4\u05d5\u05d1\u05dc\u05d5 \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d7\u05d5\u05e7\u05e8\u05d9\u05dd \u05de\u05d4\u05de\u05db\u05d5\u05e0\u05d9\u05dd \u05d4\u05dc\u05d0\u05d5\u05de\u05d9\u05d9\u05dd \u05dc\u05d1\u05e8\u05d9\u05d0\u05d5\u05ea (NIH), \u05d5\u05e4\u05d5\u05e8\u05e1\u05de\u05d5 \u05d4\u05d9\u05d5\u05dd \u05d1\u05db\u05ea\u05d1 \u05d4\u05e2\u05ea \u05e8\u05e4\u05d5\u05d0\u05ea \u05d8\u05d1\u05e2<\/em>.<\/p>\n

\u05de\u05d7\u05e7\u05e8 \u05d0\u05d7\u05d3<\/a>, \u05d1\u05e8\u05d0\u05e9\u05d5\u05ea \u05e4\u05e8\u05e0\u05e1\u05d9\u05e1 \u05e7\u05d5\u05dc\u05d9\u05e0\u05e1, MD, PhD, \u05de\u05e0\u05d4\u05dc \u05d4-NIH, \u05d4\u05e8\u05d0\u05d4 \u05e9\u05d8\u05d9\u05e4\u05d5\u05dc \u05d1\u05e2\u05db\u05d1\u05e8\u05d9 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05d1\u05ea\u05e8\u05d5\u05e4\u05d4 \u05d1\u05e9\u05dd SRP2001 r\u05d7\u05d9\u05e0\u05da \u05d0\u05ea \u05d1\u05d9\u05d8\u05d5\u05d9 \u05d4-mRNA \u05d5\u05d4\u05d7\u05dc\u05d1\u05d5\u05df \u05d4\u05de\u05d6\u05d9\u05e7 \u05e9\u05dc \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df \u05d1\u05d0\u05d1\u05d9 \u05d4\u05e2\u05d5\u05e8\u05e7\u05d9\u05dd<\/strong>, \u05d4\u05e2\u05d5\u05e8\u05e7 \u05d4\u05e8\u05d0\u05e9\u05d9 \u05d1\u05d2\u05d5\u05e3, \u05db\u05de\u05d5 \u05d2\u05dd \u05d1\u05e8\u05e7\u05de\u05d5\u05ea \u05d0\u05d7\u05e8\u05d5\u05ea. \u05d1\u05e1\u05d5\u05e3 \u05d4\u05de\u05d7\u05e7\u05e8, \u05d3\u05d5\u05e4\u05df \u05d0\u05d1\u05d9 \u05d4\u05e2\u05d5\u05e8\u05e7\u05d9\u05dd \u05e0\u05e9\u05d0\u05e8 \u05d7\u05d6\u05e7 \u05d9\u05d5\u05ea\u05e8 \u05d5\u05d4\u05e2\u05db\u05d1\u05e8\u05d9\u05dd \u05d4\u05e4\u05d2\u05d9\u05e0\u05d5 \u05d0 \u05d4\u05d9\u05e9\u05e8\u05d3\u05d5\u05ea \u05de\u05d5\u05d2\u05d1\u05e8\u05ea \u05e9\u05dc \u05de\u05e2\u05dc 60%<\/strong>.<\/p>\n

"\u05db\u05d3\u05d9 \u05e9\u05d8\u05d9\u05e4\u05d5\u05dc RNA \u05de\u05de\u05d5\u05e7\u05d3 \u05d9\u05e8\u05d0\u05d4 \u05ea\u05d5\u05e6\u05d0\u05d5\u05ea \u05db\u05d4 \u05de\u05e9\u05de\u05e2\u05d5\u05ea\u05d9\u05d5\u05ea \u05d1\u05de\u05d5\u05d3\u05dc \u05e9\u05dc \u05d1\u05e2\u05dc\u05d9 \u05d7\u05d9\u05d9\u05dd \u05e0\u05d5\u05ea\u05df \u05dc\u05d9 \u05ea\u05e7\u05d5\u05d5\u05d4 \u05e9\u05d6\u05d4 \u05d9\u05db\u05d5\u05dc \u05dc\u05d4\u05d5\u05d1\u05d9\u05dc \u05dc\u05d4\u05ea\u05e7\u05d3\u05de\u05d5\u05ea \u05de\u05e9\u05de\u05e2\u05d5\u05ea\u05d9\u05ea \u05d1\u05d8\u05d9\u05e4\u05d5\u05dc \u05d1\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4", \u05d0\u05de\u05e8 \u05e7\u05d5\u05dc\u05d9\u05e0\u05e1.<\/p>\n

\u05d4 \u05de\u05d7\u05e7\u05e8 \u05d0\u05d7\u05e8<\/a>, \u05d1\u05e8\u05d0\u05e9\u05d5\u05ea \u05d8\u05d5\u05dd \u05de\u05d9\u05e1\u05d8\u05dc\u05d9, \u05d3\u05d5\u05e7\u05d8\u05d5\u05e8\u05d8, \u05de\u05e0\u05d4\u05dc \u05d4\u05de\u05e8\u05db\u05d6 \u05dc\u05d7\u05e7\u05e8 \u05d4\u05e1\u05e8\u05d8\u05df, \u05d4\u05de\u05db\u05d5\u05df \u05d4\u05dc\u05d0\u05d5\u05de\u05d9 \u05dc\u05e1\u05e8\u05d8\u05df, NIH, \u05d4\u05e8\u05d0\u05d4 \u05d4\u05e4\u05d7\u05ea\u05d4 \u05e9\u05dc 90 - 95% \u05e9\u05dc \u05d4-RNA \u05d4\u05de\u05d9\u05d9\u05e6\u05e8 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df \u05e8\u05e2\u05d9\u05dc<\/strong> \u05d1\u05e8\u05e7\u05de\u05d5\u05ea \u05e9\u05d5\u05e0\u05d5\u05ea \u05dc\u05d0\u05d7\u05e8 \u05d8\u05d9\u05e4\u05d5\u05dc \u05d1\u05ea\u05e8\u05d5\u05e4\u05d4 \u05d1\u05e9\u05dd LB143. \u05d4\u05de\u05e2\u05d1\u05d3\u05d4 \u05e9\u05dc Misteli \u05de\u05e6\u05d0\u05d4 \u05e9\u05d4\u05e4\u05d7\u05ea\u05ea \u05d7\u05dc\u05d1\u05d5\u05df \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df \u05d4\u05d9\u05d9\u05ea\u05d4 \u05d4\u05d9\u05e2\u05d9\u05dc\u05d4 \u05d1\u05d9\u05d5\u05ea\u05e8 \u05d1\u05db\u05d1\u05d3, \u05e2\u05dd \u05e9\u05d9\u05e4\u05d5\u05e8\u05d9\u05dd \u05e0\u05d5\u05e1\u05e4\u05d9\u05dd \u05d1\u05dc\u05d1 \u05d5\u05d1\u05d0\u05d1\u05d9 \u05d4\u05e2\u05d5\u05e8\u05e7\u05d9\u05dd.<\/p>\n

\u05db\u05e2\u05ea \u05d0\u05e0\u05d5 \u05d9\u05d5\u05d3\u05e2\u05d9\u05dd \u05e9\u05d9\u05e9\u05e0\u05df \u05de\u05e1\u05e4\u05e8 \u05d3\u05e8\u05db\u05d9\u05dd \u05dc\u05d4\u05e4\u05d7\u05d9\u05ea \u05d0\u05ea \u05d4\u05d9\u05d9\u05e6\u05d5\u05e8 \u05e9\u05dc \u05d7\u05dc\u05d1\u05d5\u05df \u05d4\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df \u05d4\u05de\u05d6\u05d9\u05e7 \u05d1\u05d0\u05de\u05e6\u05e2\u05d5\u05ea \u05ea\u05e8\u05d5\u05e4\u05d5\u05ea RNA. \u05db\u05dc \u05de\u05d7\u05e7\u05e8 \u05de\u05e6\u05d0 \u05de\u05ea\u05d9\u05d7\u05d5\u05ea \u05e9\u05d5\u05e0\u05d5\u05ea \u05e9\u05dc RNA \u05d1\u05de\u05d5\u05d3\u05dc\u05d9\u05dd \u05e9\u05dc \u05d4\u05e2\u05db\u05d1\u05e8\u05d9\u05dd, \u05e9\u05db\u05d0\u05e9\u05e8 \u05d4\u05ea\u05de\u05e7\u05d3\u05d5, \u05e1\u05d9\u05e4\u05e7\u05d5 \u05de\u05e1\u05dc\u05d5\u05dc \u05d9\u05e2\u05d9\u05dc \u05dc\u05d8\u05d9\u05e4\u05d5\u05dc, \u05d5\u05db\u05ea\u05d5\u05e6\u05d0\u05d4 \u05de\u05db\u05da \u05e2\u05db\u05d1\u05e8\u05d9 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05e9\u05d7\u05d9\u05d5 \u05d4\u05e8\u05d1\u05d4 \u05d9\u05d5\u05ea\u05e8 \u05de\u05d0\u05dc\u05d4 \u05e9\u05d8\u05d5\u05e4\u05dc\u05d5 \u05d1\u05de\u05d7\u05e7\u05e8\u05d9\u05dd \u05e7\u05d5\u05d3\u05de\u05d9\u05dd \u05e2\u05dd \u05dc\u05d5\u05e0\u05e4\u05e8\u05e0\u05d9\u05d1<\/strong>, \u05d4\u05ea\u05e8\u05d5\u05e4\u05d4 \u05d4\u05d9\u05d7\u05d9\u05d3\u05d4 \u05e9\u05d0\u05d5\u05e9\u05e8\u05d4 \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d4-FDA \u05dc\u05d9\u05dc\u05d3\u05d9\u05dd \u05e2\u05dd \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4. \u05d9\u05ea\u05e8 \u05e2\u05dc \u05db\u05df, \u05d7\u05d5\u05e7\u05e8\u05d9\u05dd \u05de\u05e6\u05d0\u05d5 \u05e9\u05d8\u05d9\u05e4\u05d5\u05dc \u05de\u05e9\u05d5\u05dc\u05d1 \u05e2\u05dd \u05ea\u05e8\u05d5\u05e4\u05d5\u05ea RNA \u05d5\u05dc\u05d5\u05e0\u05e4\u05e8\u05e0\u05d9\u05d1 \u05d4\u05e4\u05d7\u05d9\u05ea \u05d0\u05ea \u05e8\u05de\u05d5\u05ea \u05d7\u05dc\u05d1\u05d5\u05df \u05d4\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05df \u05d1\u05db\u05d1\u05d3 \u05d5\u05d1\u05dc\u05d1 \u05d1\u05e6\u05d5\u05e8\u05d4 \u05d9\u05e2\u05d9\u05dc\u05d4 \u05d9\u05d5\u05ea\u05e8 \u05de\u05db\u05dc \u05d8\u05d9\u05e4\u05d5\u05dc \u05d1\u05d5\u05d3\u05d3 \u05d1\u05e4\u05e0\u05d9 \u05e2\u05e6\u05de\u05d5.<\/p>\n

"\u05e9\u05e0\u05d9 \u05d4\u05de\u05d7\u05e7\u05e8\u05d9\u05dd \u05d4\u05d7\u05e9\u05d5\u05d1\u05d9\u05dd \u05d1\u05d9\u05d5\u05ea\u05e8 \u05d4\u05dc\u05dc\u05d5 \u05de\u05d3\u05d2\u05d9\u05de\u05d9\u05dd \u05d0\u05ea \u05d4\u05ea\u05e7\u05d3\u05de\u05d5\u05ea \u05d2\u05d3\u05d5\u05dc\u05d4 \u05e9\u05e2\u05d5\u05de\u05d3\u05ea \u05d1\u05e4\u05e0\u05d9\u05e0\u05d5 \u05db\u05e2\u05ea<\/strong> \u05d1\u05ea\u05d7\u05d5\u05dd \u05d8\u05d9\u05e4\u05d5\u05dc\u05d9 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05de\u05de\u05d5\u05e7\u05d3\u05d9\u05dd", \u05d0\u05de\u05e8\u05d4 \u05d4\u05de\u05e0\u05d4\u05dc\u05ea \u05d4\u05e8\u05e4\u05d5\u05d0\u05d9\u05ea \u05e9\u05dc PRF, \u05d3"\u05e8 \u05dc\u05e1\u05dc\u05d9 \u05d2\u05d5\u05e8\u05d3\u05d5\u05df. "\u05d4\u05ea\u05e8\u05d2\u05e9\u05ea\u05d9 \u05dc\u05e2\u05d1\u05d5\u05d3 \u05e2\u05dd \u05e7\u05d1\u05d5\u05e6\u05d5\u05ea \u05d4\u05de\u05d7\u05e7\u05e8 \u05d4\u05de\u05d1\u05e8\u05d9\u05e7\u05d5\u05ea \u05d4\u05d0\u05dc\u05d4 \u05db\u05d3\u05d9 \u05dc\u05e7\u05d3\u05dd \u05d8\u05d9\u05e4\u05d5\u05dc \u05d1-RNA \u05dc\u05d9\u05dc\u05d3\u05d9\u05dd \u05e2\u05dd \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4. \u05e9\u05e0\u05d9\u05d4\u05dd \u05de\u05d7\u05e7\u05e8\u05d9\u05dd \u05de\u05e8\u05d2\u05e9\u05d9\u05dd \u05e9\u05dc \u05d4\u05d5\u05db\u05d7\u05d4 \u05dc\u05e2\u05d9\u05e7\u05e8\u05d5\u05df, \u05d5\u05db\u05df PRF \u05e0\u05e8\u05d2\u05e9 \u05dc\u05d4\u05ea\u05e7\u05d3\u05dd \u05dc\u05e7\u05e8\u05d0\u05ea \u05e0\u05d9\u05e1\u05d5\u05d9\u05d9\u05dd \u05e7\u05dc\u05d9\u05e0\u05d9\u05d9\u05dd<\/strong> \u05e9\u05de\u05d9\u05d9\u05e9\u05de\u05d9\u05dd \u05d0\u05e1\u05d8\u05e8\u05d8\u05d2\u05d9\u05d5\u05ea \u05d8\u05d9\u05e4\u05d5\u05dc \u05d0\u05dc\u05d5.<\/p>\n

 <\/p>\n

\u2014<\/p>\n

Erdos, MR, Cabral, WA, Tavarez, UL\u00a0et al.<\/i>\u00a0\u05d2\u05d9\u05e9\u05d4 \u05d8\u05d9\u05e4\u05d5\u05dc\u05d9\u05ea \u05d0\u05e0\u05d8\u05d9-\u05e1\u05e0\u05e1 \u05de\u05de\u05d5\u05e7\u05d3\u05ea \u05dc\u05ea\u05e1\u05de\u05d5\u05e0\u05ea \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05e9\u05dc \u05d4\u05d0\u05e6'\u05d9\u05e0\u05e1\u05d5\u05df-\u05d2\u05d9\u05dc\u05e4\u05d5\u05e8\u05d3.\u00a0\u05e0\u05d0\u05d8 \u05de\u05d3<\/i>\u00a0(2021). https:\/\/doi.org\/10.1038\/s41591-021-01274-0<\/p>\n

Puttaraju, M., Jackson, M., Klein, S.\u00a0et al.<\/i>\u00a0\u05e1\u05e7\u05e8 \u05e9\u05d9\u05d8\u05ea\u05d9 \u05de\u05d6\u05d4\u05d4 \u05d0\u05d5\u05dc\u05d9\u05d2\u05d5\u05e0\u05d5\u05e7\u05dc\u05d0\u05d5\u05d8\u05d9\u05d3\u05d9\u05dd \u05d0\u05e0\u05d8\u05d9-\u05e1\u05e0\u05e1 \u05d8\u05d9\u05e4\u05d5\u05dc\u05d9\u05d9\u05dd \u05dc\u05ea\u05e1\u05de\u05d5\u05e0\u05ea \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05e9\u05dc Hutchinson-Gilford.\u00a0\u05e0\u05d0\u05d8 \u05de\u05d3<\/i>\u00a0(2021). https:\/\/doi.org\/10.1038\/s41591-021-01262-4<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"

\u05d0\u05e0\u05d5 \u05e9\u05de\u05d7\u05d9\u05dd \u05dc\u05d7\u05dc\u05d5\u05e7 \u05d0\u05ea \u05d4\u05ea\u05d5\u05e6\u05d0\u05d5\u05ea \u05de\u05e9\u05e0\u05d9 \u05de\u05d7\u05e7\u05e8\u05d9 \u05e4\u05e8\u05d9\u05e6\u05ea \u05d3\u05e8\u05da \u05de\u05e8\u05d2\u05e9\u05d9\u05dd \u05e2\u05dc \u05d4\u05e9\u05d9\u05de\u05d5\u05e9 \u05d1\u05ea\u05e8\u05d5\u05e4\u05d5\u05ea RNA \u05d1\u05de\u05d7\u05e7\u05e8 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4. \u05e9\u05e0\u05d9 \u05d4\u05de\u05d7\u05e7\u05e8\u05d9\u05dd \u05de\u05d5\u05de\u05e0\u05d5 \u05e2\u05dc \u05d9\u05d3\u05d9 The Progeria Research Foundation (PRF) \u05d5\u05e0\u05db\u05ea\u05d1\u05d5 \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d4\u05de\u05e0\u05d4\u05dc\u05ea \u05d4\u05e8\u05e4\u05d5\u05d0\u05d9\u05ea \u05e9\u05dc PRF, \u05d3"\u05e8 \u05dc\u05e1\u05dc\u05d9 \u05d2\u05d5\u05e8\u05d3\u05d5\u05df. <\/p>","protected":false},"author":2,"featured_media":12414,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,1],"tags":[],"class_list":["post-12401","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-uncategorized"],"yoast_head":"\nExciting breakthroughs in RNA Therapeutics for Progeria! | The Progeria Research Foundation<\/title>\n<meta name=\"description\" content=\"Two very exciting breakthrough studies on the use of RNA therapeutics in Progeria research.\u00a0 Both studies were co-funded by The Progeria Research Foundation (PRF) and co-authored by PRF\u2019s Medical Director, Dr. Leslie Gordon.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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