{"id":17197,"date":"2023-07-25T09:44:36","date_gmt":"2023-07-25T13:44:36","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=17197"},"modified":"2025-02-15T17:45:18","modified_gmt":"2025-02-15T22:45:18","slug":"nord","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/he\/2023\/07\/25\/nord\/","title":{"rendered":"\u05de\u05d9\u05d9\u05e1\u05d3 \u05e9\u05d5\u05ea\u05e3 \u05e9\u05dc PRF \u05de\u05e9\u05de\u05e9 \u05db\u05de\u05d5\u05d1\u05d9\u05dc \u05de\u05d7\u05e9\u05d1\u05d4 \u05d1\u05e4\u05d9\u05ea\u05d5\u05d7 \u05ea\u05e8\u05d5\u05e4\u05d5\u05ea \u05dc\u05de\u05d7\u05dc\u05d5\u05ea \u05e0\u05d3\u05d9\u05e8\u05d5\u05ea"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;0px||0px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; 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global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.17.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\u05d4\u05de\u05d9\u05d9\u05e1\u05d3\u05ea \u05d5\u05d4\u05de\u05e0\u05d4\u05dc\u05ea \u05d4\u05e8\u05e4\u05d5\u05d0\u05d9\u05ea \u05e9\u05dc PRF, \u05d3&quot;\u05e8 \u05dc\u05e1\u05dc\u05d9 \u05d2\u05d5\u05e8\u05d3\u05d5\u05df, \u05d4\u05d5\u05d6\u05de\u05e0\u05d4 \u05dc\u05d0\u05d7\u05e8\u05d5\u05e0\u05d4 \u05dc\u05ea\u05e8\u05d5\u05dd \u05dc\u05e1\u05d3\u05e8\u05ea \u05e1\u05e8\u05d8\u05d5\u05e0\u05d9\u05dd \u05d7\u05d9\u05e0\u05d5\u05db\u05d9\u05d9\u05dd \u05d1\u05d4\u05e4\u05e7\u05ea \u05d4\u05d0\u05e8\u05d2\u05d5\u05df \u05d4\u05dc\u05d0\u05d5\u05de\u05d9 \u05dc\u05d4\u05e4\u05e8\u05e2\u05d5\u05ea \u05e0\u05d3\u05d9\u05e8\u05d5\u05ea (NORD), \u05d9\u05d7\u05d3 \u05e2\u05dd \u05e2\u05de\u05d9\u05ea\u05d4 \u05d3&quot;\u05e8 \u05e4\u05e8\u05e0\u05e1\u05d9\u05e1 \u05e7\u05d5\u05dc\u05d9\u05e0\u05e1, \u05d9\u05d5\u05e2\u05e5 \u05d4\u05de\u05d3\u05e2 \u05e9\u05dc \u05e0\u05e9\u05d9\u05d0 \u05d4\u05de\u05d3\u05d9\u05e0\u05d4. \u05d0\u05e8\u05d4&quot;\u05d1 \u05d5\u05dc\u05e9\u05e2\u05d1\u05e8 \u05de\u05e0\u05d4\u05dc \u05d4\u05de\u05db\u05d5\u05e0\u05d9\u05dd \u05d4\u05dc\u05d0\u05d5\u05de\u05d9\u05d9\u05dd \u05dc\u05d1\u05e8\u05d9\u05d0\u05d5\u05ea (NIH).<\/p>\n<p>\u05d4\u05e9\u05e0\u05d9\u05d9\u05dd \u05d4\u05ea\u05d1\u05e7\u05e9\u05d5 \u05dc\u05d7\u05dc\u05d5\u05e7 \u05dc\u05de\u05d9\u05d3\u05d4 \u05de\u05e0\u05d9\u05e1\u05d9\u05d5\u05e0\u05dd \u05d1\u05de\u05d7\u05e7\u05e8 \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4, \u05d4\u05d7\u05dc \u05de\u05e4\u05d9\u05ea\u05d5\u05d7 \u05d4\u05e8\u05d9\u05e9\u05d5\u05dd \u05d4\u05d1\u05d9\u05e0\u05dc\u05d0\u05d5\u05de\u05d9 \u05e9\u05dc PRF \u05d1\u05e9\u05e0\u05ea 1999. \u05d1\u05e9\u05e0\u05d9 \u05d4\u05e1\u05e8\u05d8\u05d5\u05e0\u05d9\u05dd \u05e9\u05dc\u05d4\u05dc\u05df, \u05d4\u05dd \u05d7\u05d5\u05dc\u05e7\u05d9\u05dd \u05de\u05d9\u05d3\u05e2 \u05e2\u05dc \u05de\u05e6\u05d9\u05d0\u05ea \u05d4\u05d2\u05df \u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4 \u05d1-2003, \u05d3\u05e8\u05da \u05e4\u05d9\u05ea\u05d5\u05d7 \u05e9\u05dc PRF&#039;s \u05de\u05e1\u05d3 \u05e0\u05ea\u05d5\u05e0\u05d9\u05dd \u05e8\u05e4\u05d5\u05d0\u05d9\u05d9\u05dd \u05d5\u05de\u05d7\u05e7\u05e8\u05d9\u05d9\u05dd, \u05de\u05d7\u05e7\u05e8 \u05d4\u05d4\u05d9\u05e1\u05d8\u05d5\u05e8\u05d9\u05d4 \u05d4\u05d8\u05d1\u05e2\u05d9\u05ea \u05e9\u05dc PRF, \u05d5\u05dc\u05d1\u05e1\u05d5\u05e3 \u05d1\u05d0\u05de\u05e6\u05e2\u05d5\u05ea \u05d0\u05d9\u05e9\u05d5\u05e8 \u05de\u05d9\u05e0\u05d4\u05dc \u05d4\u05de\u05d6\u05d5\u05df \u05d5\u05d4\u05ea\u05e8\u05d5\u05e4\u05d5\u05ea (FDA) \u05e9\u05dc lonafarnib, \u05d8\u05d9\u05e4\u05d5\u05dc \u05e8\u05d0\u05e9\u05d5\u05df \u05d0\u05d9 \u05e4\u05e2\u05dd \u05dc\u05e4\u05e8\u05d5\u05d2\u05e8\u05d9\u05d4, \u05db\u05d3\u05d9 \u05dc\u05d4\u05d3\u05d2\u05d9\u05dd \u05de\u05e1\u05dc\u05d5\u05dc\u05d9\u05dd \u05d0\u05e4\u05e9\u05e8\u05d9\u05d9\u05dd \u05dc\u05e7\u05d9\u05d3\u05d5\u05dd \u05de\u05d7\u05e7\u05e8 \u05e2\u05dc \u05de\u05d7\u05dc\u05d5\u05ea \u05e0\u05d3\u05d9\u05e8\u05d5\u05ea \u05e2\u05d1\u05d5\u05e8 \u05d0\u05dc\u05d4 \u05d4\u05de\u05e2\u05d5\u05e8\u05d1\u05d9\u05dd \u05d1\u05de\u05d7\u05e7\u05e8 \u05d5\u05d4\u05e1\u05d1\u05e8\u05d4 \u05e9\u05dc \u05de\u05d7\u05dc\u05d5\u05ea \u05e0\u05d3\u05d9\u05e8\u05d5\u05ea.<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/learn.rarediseases.org\/courses\/rare-disease-drug-development-series\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;These videos can be accessed HERE for free in NORD\u2019s Rare Disease Drug Development Series.&#8221; admin_label=&#8221;NORD Dr. Leslie Gordon &#038; Dr. Francis Collins&#8221; _builder_version=&#8221;4.22.1&#8243; _module_preset=&#8221;default&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#29327A&#8221; button_border_color=&#8221;#8FD2ED&#8221; background_layout=&#8221;dark&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][et_pb_text _builder_version=&#8221;4.22.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span>\u05e1\u05d3\u05e8\u05d4 \u05de\u05dc\u05d0\u05d4 \u05d6\u05d5 \u05d4\u05d9\u05d0 \u05d0\u05d9\u05e0\u05e4\u05d5\u05e8\u05de\u05d8\u05d9\u05d1\u05d9\u05ea \u05de\u05d0\u05d5\u05d3 \u05e2\u05d1\u05d5\u05e8 \u05db\u05dc \u05de\u05d9 \u05e9\u05de\u05ea\u05e2\u05e0\u05d9\u05d9\u05df \u05d1\u05e4\u05d9\u05ea\u05d5\u05d7 \u05ea\u05e8\u05d5\u05e4\u05d5\u05ea \u05d1\u05de\u05d7\u05dc\u05d5\u05ea \u05e0\u05d3\u05d9\u05e8\u05d5\u05ea, \u05d5\u05d4\u05e8\u05d0\u05d9\u05d5\u05e0\u05d5\u05ea \u05e2\u05dd \u05d3&quot;\u05e8 \u05d2\u05d5\u05e8\u05d3\u05d5\u05df \u05d5\u05d3&quot;\u05e8 \u05e7\u05d5\u05dc\u05d9\u05e0\u05e1 \u05de\u05de\u05d5\u05e7\u05de\u05d9\u05dd \u05d1\u05ea\u05d5\u05da \u05d4\u05de\u05d5\u05d3\u05d5\u05dc \u05e2\u05dc \u05dc\u05d9\u05de\u05d5\u05d3\u05d9 \u05d4\u05d9\u05e1\u05d8\u05d5\u05e8\u05d9\u05d4 \u05e9\u05dc \u05d4\u05d8\u05d1\u05e2 \u05d1\u05e1\u05d3\u05e8\u05d4 \u05d6\u05d5.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>\u05e9\u05de\u05e2 \u05d0\u05ea \u05d4\u05de\u05d9\u05d9\u05e1\u05d3 \u05d5\u05d4\u05de\u05e0\u05d4\u05dc \u05d4\u05e8\u05e4\u05d5\u05d0\u05d9 \u05e9\u05dc PRF, \u05d3&quot;\u05e8 \u05dc\u05e1\u05dc\u05d9 \u05d2\u05d5\u05e8\u05d3\u05d5\u05df, \u05d9\u05d7\u05d3 \u05e2\u05dd \u05e2\u05de\u05d9\u05ea\u05d5 \u05d4\u05d5\u05d5\u05ea\u05d9\u05e7 \u05d3&quot;\u05e8 \u05e4\u05e8\u05e0\u05e1\u05d9\u05e1 \u05e7\u05d5\u05dc\u05d9\u05e0\u05e1, \u05d7\u05d5\u05dc\u05e7\u05d9\u05dd \u05d0\u05ea \u05d4\u05de\u05e1\u05e2 \u05e9\u05dc\u05d4\u05dd \u05d1\u05e4\u05d9\u05ea\u05d5\u05d7 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