{"id":16611,"date":"2023-03-15T10:12:02","date_gmt":"2023-03-15T14:12:02","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=16611"},"modified":"2025-02-15T17:46:23","modified_gmt":"2025-02-15T22:46:23","slug":"progerinbiomarker","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/hi\/2023\/03\/15\/progerinbiomarker\/","title":{"rendered":"\u0909\u092a\u091a\u093e\u0930 \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0914\u0930 \u091c\u0940\u0935\u0928 \u0935\u093f\u0938\u094d\u0924\u093e\u0930 \u092e\u0947\u0902 \u0930\u094b\u092e\u093e\u0902\u091a\u0915 \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928 \u092e\u0940\u0932 \u0915\u0947 \u092a\u0924\u094d\u0925\u0930!"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;0px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_padding=&#8221;||5px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.24.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h5>\u0939\u092e \u0906\u092a\u0915\u0947 \u0938\u093e\u0925 \u0926\u094b \u0930\u094b\u092e\u093e\u0902\u091a\u0915 \u0936\u094b\u0927 \u0905\u092a\u0921\u0947\u091f \u0938\u093e\u091d\u093e \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0909\u0924\u094d\u0938\u093e\u0939\u093f\u0924 \u0939\u0948\u0902, \u091c\u094b \u0906\u091c \u0926\u0941\u0928\u093f\u092f\u093e \u0915\u0940 \u0936\u0940\u0930\u094d\u0937 \u0939\u0943\u0926\u092f 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\u0909\u092a\u091a\u093e\u0930 \u0938\u0947 \u091c\u0940\u0935\u093f\u0924 \u0930\u0939\u0928\u0947 \u0915\u093e \u0932\u093e\u092d \u0909\u0924\u0928\u093e \u0939\u0940 \u0905\u0927\u093f\u0915 \u0939\u094b\u0917\u093e\u0964 \u0926\u0935\u093e \u0932\u0947\u0928\u0947 \u0915\u0947 \u0926\u094c\u0930\u093e\u0928 \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u0928 \u0915\u093e \u0938\u094d\u0924\u0930 \u0932\u0917\u092d\u0917 30-60% \u0924\u0915 \u0915\u092e \u0939\u094b \u0917\u092f\u093e, \u0914\u0930 10 \u0938\u093e\u0932 \u0938\u0947 \u0905\u0927\u093f\u0915 \u0938\u092e\u092f \u0924\u0915 \u0909\u092a\u091a\u093e\u0930 \u092a\u0930 \u0930\u0939\u0928\u0947 \u0935\u093e\u0932\u0947 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u0940 \u091c\u0940\u0935\u0928 \u092a\u094d\u0930\u0924\u094d\u092f\u093e\u0936\u093e \u0914\u0938\u0924\u0928 4.5 \u0938\u093e\u0932 \u092c\u0922\u093c \u091c\u093e\u0924\u0940 \u0939\u0948\u0964 <strong>\u0914\u0938\u0924 \u091c\u0940\u0935\u0928\u0915\u093e\u0932 \u092e\u0947\u0902 30% \u0938\u0947 \u0905\u0927\u093f\u0915 \u0915\u0940 \u0935\u0943\u0926\u094d\u0927\u093f, 14.5 \u0935\u0930\u094d\u0937 \u0938\u0947 \u0932\u0917\u092d\u0917 20 \u0935\u0930\u094d\u0937 \u0915\u0940 \u0906\u092f\u0941 \u0924\u0915<\/strong>!<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_button button_url=&#8221;https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/03\/Progerin-Plasma-Biomarker-press-release-FINAL.pdf&#8221; button_text=&#8221;To learn more, see our press release here&#8221; button_alignment=&#8221;center&#8221; admin_label=&#8221;biomarker pdf&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#00B2E2&#8243; button_border_width=&#8221;0px&#8221; button_border_color=&#8221;#00B2E2&#8243; background_layout=&#8221;dark&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][et_pb_text _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"font-weight: 400;\"><strong>\u201c\u0907\u0938 \u092a\u0949\u0921\u0915\u093e\u0938\u094d\u091f \u092a\u0930 \u0938\u093e\u091d\u093e \u0915\u0940 \u0917\u0908 \u0905\u092c \u0924\u0915 \u0915\u0940 \u0938\u092c\u0938\u0947 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0915\u0939\u093e\u0928\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 \u0938\u0947 \u090f\u0915\u201d<br \/><\/strong>\u2013 \u0921\u0949. \u0915\u0948\u0930\u094b\u0932\u093f\u0928 \u0932\u0948\u092e, \u0935\u093f\u0936\u094d\u0935 \u092a\u094d\u0930\u0938\u093f\u0926\u094d\u0927 \u0939\u0943\u0926\u092f \u0930\u094b\u0917 \u0935\u093f\u0936\u0947\u0937\u091c\u094d\u091e \u0914\u0930 \u092a\u0949\u0921\u0915\u093e\u0938\u094d\u091f \u0915\u0940 \u0939\u094b\u0938\u094d\u091f <em>\u092a\u0930\u093f\u0938\u0902\u091a\u0930\u0923 \u091a\u093e\u0932\u0942, <\/em>\u0909\u0938 \u092f\u093e\u0924\u094d\u0930\u093e \u092a\u0930 \u091c\u094b \u0907\u0928 \u0930\u094b\u092e\u093e\u0902\u091a\u0915 \u0928\u093f\u0937\u094d\u0915\u0930\u094d\u0937\u094b\u0902 \u0924\u0915 \u0932\u0947 \u0917\u0908<em>. <\/em><strong>\u092a\u0942\u0930\u093e \u0938\u093e\u0915\u094d\u0937\u093e\u0924\u094d\u0915\u093e\u0930 \u0938\u0941\u0928\u0947\u0902<\/strong> \u0907\u0938 \u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u0947 \u0917\u0939\u0928 \u092a\u094d\u0930\u092d\u093e\u0935 \u0915\u0947 \u092c\u093e\u0930\u0947 \u092e\u0947\u0902 \u0938\u0940\u0927\u0947 \u0921\u0949. \u0917\u0949\u0930\u094d\u0921\u0928 \u0938\u0947 \u0938\u0941\u0928\u0947\u0902\u0964 <a href=\"https:\/\/r20.rs6.net\/tn.jsp?f=001cLXauJ5R6hFjgU6UNVj8z1ubk-cU5xChRkxoAUyz5uADnaWoiVSXmGDO6nDbCFI6BusWzoswFG0iru8PXvTinayQ2nuBWZkmbHn8pNOQ-qsUB1VpMUndro-VBH-aWDvJUzVgfNvTim0xjz6cUlYUsEKvW6Ac2WVwzATNn1BxwmDhQLC1rKekmK7seL8r8YfP&amp;c=WFQd6JESprJMCu4rKF2oA9DZh92aflFfVggkN5fMTdEL4z9YqYGm8g==&amp;ch=BuG-LaRM92CDJVKzSsfwhIYuKm0CXdEFhP1J1G8vN4oKaWQGcoaRLw==\"><strong>\u092f\u0939\u093e\u0901<\/strong><\/a> <a href=\"https:\/\/r20.rs6.net\/tn.jsp?f=001cLXauJ5R6hFjgU6UNVj8z1ubk-cU5xChRkxoAUyz5uADnaWoiVSXmGDO6nDbCFI6BusWzoswFG0iru8PXvTinayQ2nuBWZkmbHn8pNOQ-qsUB1VpMUndro-VBH-aWDvJUzVgfNvTim0xjz6cUlYUsEKvW6Ac2WVwzATNn1BxwmDhQLC1rKekmK7seL8r8YfP&amp;c=WFQd6JESprJMCu4rKF2oA9DZh92aflFfVggkN5fMTdEL4z9YqYGm8g==&amp;ch=BuG-LaRM92CDJVKzSsfwhIYuKm0CXdEFhP1J1G8vN4oKaWQGcoaRLw==\">(<\/a>(6:41 \u092a\u0930 \u0936\u0941\u0930\u0942)<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/circulation.libsyn.com\/circulation-june-6-2023-issue&#8221; button_text=&#8221;Hear Dr. Leslie Gordon on Circulation on the Run podcast&#8221; button_alignment=&#8221;center&#8221; admin_label=&#8221;circulation podcast&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#00B2E2&#8243; button_border_width=&#8221;0px&#8221; button_border_color=&#8221;#00B2E2&#8243; background_layout=&#8221;dark&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][et_pb_text _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"font-weight: 400;\">\u0914\u0930 \u091c\u0942\u0928 \u092e\u0947\u0902, \u0926\u094b \u0938\u0902\u092a\u093e\u0926\u0915\u0940\u092f \u092a\u0924\u094d\u0930 <a href=\"https:\/\/www.progeriaresearch.org\/hi\/progerinbiomarker\/#2\">(2) <\/a>\u0914\u0930 <a href=\"https:\/\/www.progeriaresearch.org\/hi\/progerinbiomarker\/#3\">(3)<\/a> \u092e\u0947\u0902 \u092a\u094d\u0930\u0915\u093e\u0936\u093f\u0924 \u0939\u0941\u090f \u0925\u0947 <i>\u092a\u094d\u0930\u0938\u093e\u0930 <\/i>\u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u092f\u093e \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u092c\u091a\u094d\u091a\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0909\u092a\u091a\u093e\u0930 \u0914\u0930 \u0907\u0932\u093e\u091c \u0915\u094b \u0906\u0917\u0947 \u092c\u0922\u093c\u093e\u0928\u0947 \u0924\u0925\u093e \u0909\u092e\u094d\u0930 \u092c\u0922\u093c\u0928\u0947 \u0915\u094b \u092c\u0947\u0939\u0924\u0930 \u0922\u0902\u0917 \u0938\u0947 \u0938\u092e\u091d\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0907\u0938 \u092c\u093e\u092f\u094b\u092e\u093e\u0930\u094d\u0915\u0930 \u0915\u0947 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u092e\u0939\u0924\u094d\u0935 \u092a\u0930 \u092a\u094d\u0930\u0915\u093e\u0936 \u0921\u093e\u0932\u093e \u0917\u092f\u093e\u0964<\/p>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;papers&#8221; module_id=&#8221;1&#8243; _builder_version=&#8221;4.19.5&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-16634 alignleft\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/03\/Circulation-logo-300x74.jpg\" alt=\"\" width=\"219\" height=\"54\" srcset=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/03\/Circulation-logo-300x74.jpg 300w, https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/03\/Circulation-logo.jpg 400w\" sizes=\"(max-width: 219px) 100vw, 219px\" \/><\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<p>(1) \u0917\u0949\u0930\u094d\u0921\u0928, \u090f\u0932\u092c\u0940, \u0928\u0949\u0930\u093f\u0938, \u0921\u092c\u094d\u0932\u0942., \u0939\u0948\u092e\u094d\u0930\u0947\u0928, \u090f\u0938., <em>\u090f\u091f \u0905\u0932<\/em>\u0939\u091a\u093f\u0902\u0938\u0928-\u0917\u093f\u0932\u092b\u094b\u0930\u094d\u0921 \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u092f\u093e \u0938\u093f\u0902\u0921\u094d\u0930\u094b\u092e \u0935\u093e\u0932\u0947 \u092e\u0930\u0940\u091c\u094b\u0902 \u092e\u0947\u0902 \u092a\u094d\u0932\u093e\u091c\u094d\u092e\u093e \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u0928: \u0907\u092e\u094d\u092f\u0942\u0928\u094b\u0938\u0947 \u0935\u093f\u0915\u093e\u0938 \u0914\u0930 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928\u0964 <em>\u092a\u094d\u0930\u0938\u093e\u0930<\/em>, 2023<\/p>\n<p>(2) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37276254\/\">\u0939\u091a\u093f\u0902\u0938\u0928-\u0917\u093f\u0932\u092b\u094b\u0930\u094d\u0921 \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u092f\u093e \u0938\u093f\u0902\u0921\u094d\u0930\u094b\u092e \u092e\u0947\u0902 \u0939\u0943\u0926\u092f \u0938\u0902\u092c\u0902\u0927\u0940 \u0905\u0938\u093e\u092e\u093e\u0928\u094d\u092f\u0924\u093e\u0913\u0902 \u0915\u0940 \u092a\u094d\u0930\u0917\u0924\u093f: \u090f\u0915 \u0938\u0902\u092d\u093e\u0935\u093f\u0924 \u0905\u0928\u0941\u0926\u0948\u0930\u094d\u0927\u094d\u092f \u0905\u0927\u094d\u092f\u092f\u0928\u0964<\/a><br \/>\u0913\u0932\u094d\u0938\u0928 \u090f\u092b\u091c\u0947, \u0917\u0949\u0930\u094d\u0921\u0928 \u090f\u0932\u092c\u0940, \u0938\u094d\u092e\u0942\u091f \u090f\u0932, \u0915\u094d\u0932\u0947\u0928\u092e\u0948\u0928 \u090f\u092e\u0908, \u0917\u0947\u0930\u0939\u093e\u0930\u094d\u0921-\u0939\u0930\u092e\u0928 \u090f\u092e, \u0939\u0947\u0917\u0921\u093c\u0947 \u090f\u0938\u090f\u092e, \u092e\u0941\u0915\u0941\u0902\u0926\u0928 \u090f\u0938, \u092e\u0939\u094b\u0928\u0940 \u091f\u0940, \u092e\u093e\u0938\u093e\u0930\u094b \u091c\u0947, \u0939\u093e \u090f\u0938, \u092a\u094d\u0930\u0915\u093e\u0936 \u090f.<br \/><em>\u092a\u094d\u0930\u0938\u093e\u0930<\/em>. 2023 \u091c\u0942\u0928 6;147(23):1782-1784. doi: 10.1161\/CIRCULATIONAHA.123.064370. \u0908\u092a\u092c 2023 \u091c\u0942\u0928 5.<\/p>\n<p style=\"font-weight: 400;\">(3) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37276251\/\">\u0939\u091a\u093f\u0902\u0938\u0928-\u0917\u093f\u0932\u092b\u094b\u0930\u094d\u0921 \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u092f\u093e \u0938\u093f\u0902\u0921\u094d\u0930\u094b\u092e \u092e\u0947\u0902 \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u0928 \u0914\u0930 \u0939\u0943\u0926\u092f \u0930\u094b\u0917 \u0915\u0940 \u092a\u094d\u0930\u0917\u0924\u093f \u0915\u093e \u092a\u0924\u093e \u0932\u0917\u093e\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0906\u0938\u093e\u0928\u0940 \u0938\u0947 \u0909\u092a\u0932\u092c\u094d\u0927 \u0909\u092a\u0915\u0930\u0923\u0964 <\/a><br \/>\u090f\u0930\u093f\u0915\u094d\u0938\u0928 \u090f\u092e, \u0939\u094c\u0917\u093e \u0915\u0947, \u0930\u0947\u0935\u0947\u091a\u094b\u0928 \u091c\u0940\u0964<br \/><em>\u092a\u094d\u0930\u0938\u093e\u0930<\/em>. 2023 \u091c\u0942\u0928 6;147(23):1745-1747. doi: 10.1161\/CIRCULATIONAHA.123.064765. \u0908\u092a\u092c 2023 \u091c\u0942\u0928 5.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>\u0939\u092e\u093e\u0930\u0940 \u0936\u094b\u0927 \u091f\u0940\u092e \u0928\u0947 \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u0928 \u0915\u094b \u092e\u093e\u092a\u0928\u0947 \u0915\u093e \u090f\u0915 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0928\u092f\u093e \u0924\u0930\u0940\u0915\u093e \u0916\u094b\u091c\u093e \u0939\u0948, \u091c\u094b \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u092f\u093e \u0915\u093e \u0915\u093e\u0930\u0923 \u092c\u0928\u0928\u0947 \u0935\u093e\u0932\u093e \u0935\u093f\u0937\u0948\u0932\u093e \u092a\u094d\u0930\u094b\u091f\u0940\u0928 \u0939\u0948\u0964 \u0907\u0938 \u0916\u094b\u091c \u0915\u0947 \u0938\u093e\u0925, \u0935\u0948\u091c\u094d\u091e\u093e\u0928\u093f\u0915\u094b\u0902 \u0928\u0947 \u092f\u0939 \u092d\u0940 \u092a\u093e\u092f\u093e \u0915\u093f \u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u092f\u093e \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u092c\u091a\u094d\u091a\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0932\u094b\u0928\u092b\u093e\u0930\u0928\u093f\u092c \u0915\u093e \u0926\u0940\u0930\u094d\u0918\u0915\u093e\u0932\u093f\u0915 \u0932\u093e\u092d \u0939\u092e\u093e\u0930\u0940 \u0938\u094b\u091a \u0938\u0947 \u0915\u0939\u0940\u0902 \u091c\u093c\u094d\u092f\u093e\u0926\u093e \u0939\u0948\u0964<br \/>\n\u092a\u094d\u0930\u094b\u091c\u0947\u0930\u093f\u092f\u093e \u0938\u092e\u0941\u0926\u093e\u092f \u0915\u0947 \u0932\u093f\u090f \u0907\u0928 \u0926\u094b \u0928\u093f\u0937\u094d\u0915\u0930\u094d\u0937\u094b\u0902 \u0915\u093e \u0915\u094d\u092f\u093e \u092e\u0924\u0932\u092c \u0939\u0948? <\/p>","protected":false},"author":2,"featured_media":16614,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,1],"tags":[],"class_list":["post-16611","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Progerin Biomarker | The Progeria Research Foundation<\/title>\n<meta name=\"description\" content=\"Our research team has discovered a vital new way to measure progerin, the toxic protein that causes Progeria. With this discovery, scientists also found that the long-term benefit of lonafarnib for children with Progeria is greater than we thought. What do these two findings mean for the Progeria community? Read more here\u2026\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/hi\/2023\/03\/15\/progerinbiomarker\/\" \/>\n<meta property=\"og:locale\" content=\"hi_IN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Progerin Biomarker | The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"Our research team has discovered a vital new way to measure progerin, the toxic protein that causes Progeria. With this discovery, scientists also found that the long-term benefit of lonafarnib for children with Progeria is greater than we thought. What do these two findings mean for the Progeria community? 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