{"id":2128,"date":"2005-05-16T20:41:26","date_gmt":"2005-05-16T20:41:26","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=2128"},"modified":"2020-12-09T11:08:36","modified_gmt":"2020-12-09T16:08:36","slug":"exciting-news-on-potential-drug-treatments","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/id\/2005\/05\/16\/exciting-news-on-potential-drug-treatments\/","title":{"rendered":"Berita Menarik tentang Potensi Pengobatan dengan Obat"},"content":{"rendered":"

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Agustus 2005 \u2013 Februari 2006: Para peneliti telah menerbitkan studi yang mendukung pengobatan obat potensial untuk anak-anak penderita Progeria. Inhibitor farnesyltransferase (FTI), yang awalnya dikembangkan untuk kanker, mampu membalikkan kelainan struktur nuklir dramatis yang merupakan ciri khas sel dari anak-anak penderita Progeria.<\/p>\n

Berikut adalah beberapa jawaban atas Pertanyaan yang Sering Diajukan tentang FTI dan temuan terbaru ini<\/a><\/strong><\/p>\n

Dari laboratorium Susan Michaelis di Fakultas Kedokteran Universitas Johns Hopkins dan Universitas Seattle. Penulis pertama: Monica Mallampalli.<\/a> PRF mendanai penelitian ini.<\/em> klik disini<\/a> untuk artikelnya \"<\/p>\n

Dari laboratorium Dr. Thomas Glover di Universitas Michigan.<\/a> Penulis pertama: Michael W. Glynn. PRF mendanai penelitian ini.<\/em> klik disini<\/a> untuk artikelnya \"<\/p>\n

Dari laboratorium Dr. Francis Collins di National Human Genome Research Institute: Penulis pertama: Brian Capell.<\/a> Penulis tambahan: Direktur Medis PRF Dr. Leslie Gordon<\/em><\/p>\n

Capell BC, Erdos MR, Madigan JP, Fiordalisi JJ, Varga R, Conneely KN, dkk. Menghambat farnesilasi progerin mencegah terbentuknya bercak nuklir yang menjadi ciri khas sindrom progeria Hutchinson-Gilford.<\/em> Proc Natl Acad Sci USA 2005;102(36):12879-84.<\/p>\n

Dari laboratorium Dr. Loren Fong dan Steven Young di UCLA.<\/a> PRF membantu mendanai penelitian ini.<\/em><\/p>\n

Fong LG, Frost D, Meta M, Qiao X, Yang SH, Coffinier C, dkk. Penghambat protein farnesyltransferase memperbaiki penyakit pada model tikus progeria.<\/em> Sains 2006;311(5767):1621-3.<\/p>\n

Berikut ini adalah beberapa media yang meliput berita ini:<\/strong><\/p>\n

Berita ABC.COM<\/strong>
Obat Kanker Dapat Melawan Penyakit Penuaan Cepat yang Langka: 29 September 2005 (artikel tidak tersedia lagi)
WAKTU LA<\/strong>
Penelitian Menunjukkan Obat-obatan Dapat Memblokir Penyakit Penuaan Dini (artikel tidak tersedia lagi)
Majalah FORBES <\/strong>
Obat Kanker Dapat Melawan Penyakit Penuaan Cepat (artikel tidak tersedia lagi)
Jurnalis<\/strong>
Obat Kanker Dapat Mengobati Sindrom Penuaan pada Anak (artikel tidak tersedia lagi)
BERITA KESEHATANDIGEST.COM<\/strong>
Memblokir Sindrom Penuaan Dini dengan Obat Antikanker (artikel tidak tersedia lagi)<\/p>\n<\/div>\n

[\/et_pb_teks][\/et_pb_kolom][\/et_pb_baris][\/et_pb_bagian]<\/p>","protected":false},"excerpt":{"rendered":"

[et_pb_section fb_built=\u201d1\u2033 _builder_version=\u201d3.22\u2033][et_pb_row _builder_version=\u201d3.25\u2033 ukuran_latar belakang=\u201dawal\u201d posisi_latar belakang=\u201dkiri_atas\u201d pengulangan_latar belakang=\u201dulangi\u201d][et_pb_column jenis=\u201d4_4\u2033 _builder_version=\u201d3.25\u2033 bantalan_khusus=\u201d|||\u201d custom_padding__hover=\u201d|||\u201d][et_pb_text _builder_version=\u201d4.6.5\u2033 background_size=\u201dinitial\u201d background_position=\u201dtop_left\u201d background_repeat=\u201drepeat\u201d hover_enabled=\u201d0\u2033 sticky_enabled=\u201d0\u2033] Agustus 2005 \u2013 Februari 2006: Para peneliti telah menerbitkan studi yang mendukung pengobatan obat potensial untuk anak-anak penderita Progeria. Inhibitor farnesyltransferase (FTI), yang awalnya dikembangkan untuk kanker, mampu membalikkan kelainan struktur nuklir dramatis yang menjadi ciri khas [\u2026]<\/p>","protected":false},"author":1,"featured_media":2043,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"

[vc_custom_heading text=\"Exciting News on Potential Drug Treatments\" font_container=\"tag:h1|text_align:left\" use_theme_fonts=\"yes\"]<\/p>

August 2005 \u2013February 2006: Researchers have published studies that support a potential drug treatment for children with Progeria. Farnesyltransferase inhibitors (FTIs), originally developed for cancer, are capable of reversing the dramatic nuclear structure abnormalities that are the hallmark of cells from children with Progeria.<\/p>

Here are some answers to Frequently Asked Questions about FTI's and these recent findings<\/a><\/strong><\/p>

From the lab of Susan Michaelis at Johns Hopkins University School of Medicine and the University of Seattle. First author: Monica Mallampalli.<\/a> PRF funded this study.<\/em> Click here<\/a> for the article \"<\/p>

From the lab of Dr. Thomas Glover at the University of Michigan.<\/a> First author: Michael W. Glynn. PRF funded this study.<\/em> Click here<\/a> for the article \"<\/p>

From the lab of Dr. Francis Collins at the National Human Genome Research Institute: First author: Brian Capell.<\/a> Additional author: PRF's Medical Director Dr. Leslie Gordon<\/em><\/p>

Capell BC, Erdos MR, Madigan JP, Fiordalisi JJ, Varga R, Conneely KN, et al. Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.<\/em> Proc Natl Acad Sci U S A 2005;102(36):12879-84.<\/p>

From the lab of Drs. Loren Fong and Steven Young at UCLA.<\/a> PRF helped fund this study.<\/em><\/p>

Fong LG, Frost D, Meta M, Qiao X, Yang SH, Coffinier C, et al. A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.<\/em> Science 2006;311(5767):1621-3.<\/p>

Here are just a few of the many media outlets that have covered this story:<\/strong><\/p>

ABCNEWS.COM<\/strong>
Cancer Drugs May Fight Rare Rapid-Aging Disease: Sept.29, 2005<\/a> (article no longer available)
LA TIMES<\/strong>
Research Shows Drugs Could Block Early-Aging Disease<\/a>
FORBES <\/strong>
Cancer Drugs May Fight Rapid-Aging Disease<\/a>\u00a0(article no longer available)
REUTERS<\/strong>
Cancer Drugs May Treat Aging Syndrome in Children<\/a> (article no longer available)
HEALTHNEWSDIGEST.COM<\/strong>
Blocking a Premature Aging Syndrome with Anticancer Drugs<\/a>\u00a0(article no longer available)<\/p>
You will need the Adobe Acrobat Plugin to view and print forms. If you do not have the plugin you can get it here<\/a>.<\/td>\"<\/a><\/td><\/tr><\/tbody><\/table><\/div>","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-2128","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"\nExciting News on Potential Drug Treatments - The Progeria Research Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/id\/2005\/05\/16\/exciting-news-on-potential-drug-treatments\/\" \/>\n<meta property=\"og:locale\" content=\"id_ID\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Exciting News on Potential Drug Treatments - The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"[et_pb_section fb_built=”1″ _builder_version=”3.22″][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.6.5″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ sticky_enabled=”0″] August 2005 \u2013February 2006: Researchers have published studies that support a potential drug treatment for children with Progeria. 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