{"id":19982,"date":"2025-02-14T18:32:28","date_gmt":"2025-02-14T23:32:28","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?page_id=19982"},"modified":"2025-10-31T09:22:50","modified_gmt":"2025-10-31T13:22:50","slug":"2025-agenda","status":"publish","type":"page","link":"https:\/\/www.progeriaresearch.org\/it\/2025-agenda\/","title":{"rendered":"Programma del workshop 2025"},"content":{"rendered":"

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\n[\/et_pb_fullwidth_image][\/et_pb_section][et_pb_section fb_built=”1″ use_custom_gutter=”on” gutter_width=”1″ specialty=”on” padding_left_1=”35px” padding_left_2=”35px” padding_2_tablet=”|||0px” padding_2_phone=”|||0px” padding_2_last_edited=”on|desktop” module_class_1=”sidebar-secondary-nav” module_class=”handprint-bg” _builder_version=”4.27.4″ background_image=”https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/blue-handprint-only.png” parallax=”on” parallax_method=”off” inner_width=”100%” inner_max_width=”100%” custom_padding=”0|0px|0px|0px|false|false” z_index_tablet=”500″ border_width_top=”10px” border_color_top=”#8fd2ed” use_custom_width=”on” width_unit=”off” custom_width_percent=”100%” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_sidebar area=”et_pb_widget_area_32″ disabled_on=”off|off|off” admin_label=”Workshop 2025″ module_class=”subpage-sidebars” _builder_version=”4.27.4″ _dynamic_attributes=”link_option_url” animation_style=”fade” link_option_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wb3N0Iiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjEyODc3In19@” z_index_tablet=”500″ border_width_right=”5px” locked=”off” global_colors_info=”{}”][\/et_pb_sidebar][\/et_pb_column][et_pb_column type=”3_4″ specialty_columns=”3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_row_inner custom_padding_last_edited=”on|phone” _builder_version=”4.16″ custom_padding=”39.4375px|35px|6px||false|false” custom_padding_tablet=”|35px||35px||true” custom_padding_phone=”” animation_direction=”top” global_colors_info=”{}”][et_pb_column_inner saved_specialty_column_type=”3_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_button button_url=”https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2025\/10\/2025-PRF-Workshop-Agenda-10.28.25.pdf” button_text=” Agenda for The Progeria Research Foundation International Scientific Workshop ” button_alignment=”center” disabled_on=”off|off|off” admin_label=”Agenda pdf” _builder_version=”4.27.4″ _module_preset=”default” button_text_size=”25px” button_bg_color=”#FA9405″ button_border_radius=”50px” background_layout=”dark” custom_margin=”3px||30px||false|false” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner _builder_version=”4.17.6″ _module_preset=”default” custom_padding=”38px|||||” global_colors_info=”{}”][et_pb_column_inner saved_specialty_column_type=”3_4″ _builder_version=”4.17.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_text disabled_on=”off|off|off” admin_label=”Agenda Wednesday” _builder_version=”4.27.4″ _module_preset=”default” header_text_color=”#000000″ custom_margin=”|25px|||false|false” custom_padding=”|0px||||” border_width_all=”4px” border_color_all=”#00B2E2″ box_shadow_style=”preset6″ global_colors_info=”{}”]<\/p>\n

 <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Agenda at a Glance<\/strong><\/span><\/h3>\n
<\/h5>\n
Note: Agenda Subject to Change<\/strong><\/em><\/span><\/h5>\n<\/td>\n<\/tr>\n

\n
Wednesday, October 29, 2025<\/strong><\/span><\/h5>\n<\/td>\n<\/tr>\n
Time<\/strong><\/td>\nSession<\/strong><\/td>\nSpeaker<\/strong><\/td>\n<\/tr>\n
\u00a0 3:00-5:00 PM<\/td>\n\u00a0 Registration & Poster Set-Up<\/td>\n<\/tr>\n
\u00a0 5:00-5:15 PM<\/td>\n\u00a0 Introduction & Greetings from PRF<\/td>\n\n

Audrey Gordon, Esq.
Executive Director
The Progeria Research Foundation<\/p>\n

Scott Berns, MD, MPH, FAAP
Board Chair
The Progeria Research Foundation<\/p>\n

Leslie Gordon, MD, PhD
Medical Director
The Progeria Research Foundation<\/span><\/p>\n<\/td>\n<\/tr>\n

\u00a0 5:15-5:25 PM<\/td>\nPRF Medical Research Remarks<\/td>\nLeslie Gordon<\/td>\n<\/tr>\n
\u00a0 5:25-6:25 PM<\/td>\n\u00a0 \u201cComing of Age\u201d Conversations:\u00a0 Young Adults with HGPS as Research Partners<\/td>\nModerator: Merlin Waldron, USA
Kaylee Halko, USA
Amber Vandeweert-Wielemans, Belgium
Michiel Vandeweert, Belgium
Riccardo Zanolli, Italy<\/td>\n<\/tr>\n
\u00a0 6:25-6:35 PM<\/td>\n\u00a0 Musical Kickoff<\/td>\nFrancis Collins, MD, PhD<\/td>\n<\/tr>\n
\u00a0 6:35-6:45 PM<\/td>\n\u00a0 Group Photo \u2013 All Attendees!<\/td>\n<\/td>\n<\/tr>\n
\u00a0 6:30 PM<\/td>\n\u00a0 Dinner & Collaborative Interaction Time<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/et_pb_text][et_pb_text disabled_on=”off|off|off” admin_label=”Agenda Thursday” _builder_version=”4.27.4″ _module_preset=”default” header_text_color=”#000000″ custom_margin=”|25px|||false|false” custom_padding=”|0px||||” border_width_all=”4px” border_color_all=”#00B2E2″ box_shadow_style=”preset6″ global_colors_info=”{}”]<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n
Thursday, October 30, 2025<\/strong><\/span><\/h5>\n<\/td>\n<\/tr>\n
\u00a0 7:45 AM-8:00 PM<\/td>\nRegistration Desk Open<\/td>\n<\/tr>\n
\u00a0 8:00-9:00 AM<\/td>\nBridging the Bench Mentor Session<\/td>\n<\/tr>\n
\u00a0 9:00-9:30 AM<\/td>\nBreakfast<\/td>\n<\/td>\n<\/tr>\n
\u00a0Current Treatment Trial Outcomes in Progeria\u00a0 \u00a0 \u00a0 \u00a0<\/em>Moderator: Mark Kieran, MD, PhD, VP Clinical Development, Day One Biopharmaceuticals<\/td>\n<\/tr>\n
\u00a0 9:30-9:50 AM<\/td>\nNew Trial: Disease Progression in Progeria<\/td>\nLeslie Gordon, MD, PhD<\/td>\n<\/tr>\n
\u00a0 9:55-10:15 AM<\/td>\nPhase 2a Progerinin in Clinical Treatment Trial for Progeria<\/td>\nMonica Kleinman, MD
Boston Children\u2019s Hospital Harvard Medical School<\/td>\n<\/tr>\n
\u00a010:20-10:40 AM<\/td>\nTools for Pivotal Science and Medicine in Progeria: Biomarker Assay Development, Qualification and Reagent Generation<\/td>\nBarbara Natke, PhD
Chief Business Officer and Biomarker Lead
The Progeria Research Foundation<\/td>\n<\/tr>\n
\u00a010:45-11:05 AM<\/td>\nLate-Stage Treatment of Aortic Stenosis in HGPS<\/td>\nAshwin Prakash, MD
Pediatric Cardiologist
Boston Children\u2019s Hospital<\/span><\/td>\n<\/tr>\n
\u00a011:10-11:30 AM<\/td>\nBreak<\/td>\n<\/td>\n<\/tr>\n
\u00a011:35-11:50 AM<\/td>\nLate Breaking Presentation: <\/em>A novel progerin-producing nonclassic HGPS phenotype:\u00a0 What progeria might look like with effective therapy<\/td>\nLinda Bulmer, MD
Sahlgrenska University Hospital
Gothenburg, Sweden<\/span><\/td>\n<\/tr>\n
\u00a011:55 AM-12:20 PM<\/td>\nPoster Lightning Round<\/td>\nPoster Presenters<\/td>\n<\/tr>\n
\u00a012:20-1:30 PM<\/td>\nLunch and Collaborative Interaction Time<\/td>\n<\/td>\n<\/tr>\n
Cardiovascular Disease in HGPS and Aging\u00a0 \u00a0 \u00a0 \u00a0<\/em>Moderator: Maria Eriksson, PhD, Professor, Karolinska Institute<\/td>\n<\/tr>\n
\u00a01:30 -1:50 PM<\/td>\nNew Autoptical Pathological findings Revealing HGPS Pathophysiology<\/td>\nAndrea Porzionato, PhD
Professor
University of Padova<\/span><\/td>\n<\/tr>\n
\u00a01:55-2:15 PM<\/td>\nSingle-cell Analysis Reveals the Phenotypic Landscape of Arterial Cells in Progeria<\/td>\nMaria Eriksson, PhD
Lara Garcia Merino, MSc<\/td>\n<\/tr>\n
\u00a02:20-2:40 PM<\/td>\nEvaluation of Coronary Artery and Aortic Calcium in Progeria by Computed Tomography<\/td>\nSunil Ghelani, MD
Attending Cardiologist
Boston Children\u2019s Hospital\u00a0<\/span><\/td>\n<\/tr>\n
\u00a02:45-3:05 PM<\/td>\nAngiopoietin-2: A Potential Therapeutic Target for Vascular Protection in Hutchinson-Gilford Progeria Syndrome<\/td>\nLizzy Izydore, BS \u00a0(for Kan Cao, PhD)
University of Maryland<\/span><\/td>\n<\/tr>\n
\u00a03:05-3:25 PM<\/td>\nBreak<\/strong><\/td>\n<\/td>\n<\/tr>\n
\u00a03:25-3:45 PM<\/td>\nBridging the gap: Translating CVpathology to clinical assessments and research study design<\/td>\nKeri Shafer, MD & Sheila Hegde, MD
UT Southwestern Medical Center\u00a0<\/span><\/td>\n<\/tr>\n
\u00a03:50-4:10 PM<\/td>\nProgeria and Vascular Calcification: Diet and Treatments<\/td>\nRicardo Villa Bellosta, PhD
Group Leader, Ramon y Cajal Researcher
Center for Research in Molecular Medicine and Chronic Diseases<\/td>\n<\/tr>\n
\u00a04:15-4:25 PM<\/td>\nPoster Elevation \u2013 LRRK2 Knockdown Rescues Progerin-Induced Premature Aging<\/td>\nLukas Mann
Institute of Molecular Biology Mainz, Germany<\/td>\n<\/tr>\n
\u00a04:25-4:35 PM<\/td>\nPoster Elevation \u2013 National Interview Survey for Patients with Hutchinson-Gilford Progeria Syndrome and Progeroid Laminopathies and Their Families in Japan<\/td>\nYuko Okawa, MD
Oita University, Japan<\/span><\/td>\n<\/tr>\n
\u00a04:35 -5:30 PM<\/td>\nBreak <\/strong>Adjourn Until Poster Session & Dinner<\/td>\n<\/td>\n<\/tr>\n
\u00a05:30-6:30 PM<\/td>\nPoster Session Part 1<\/td>\nEven Numbered Posters<\/td>\n<\/tr>\n
\u00a06:00-7:00 PM<\/td>\nDinner and Collaborative Interaction Time<\/td>\n<\/tr>\n
\u00a07:00-8:00 PM<\/td>\nPoster Session Part 2<\/td>\n\u00a0 Odd Numbered Posters<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

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\n
Friday, October 31, 2025<\/strong><\/span><\/h5>\n<\/td>\n<\/tr>\n
\u00a0 7:30 AM-2:00 PM<\/td>\nRegistration Desk Open<\/td>\n<\/tr>\n
\u00a0 7:30-8:30 AM<\/td>\nBreakfast & Networking<\/td>\n<\/tr>\n
Progeria Treatment Discovery for a Healthy Future\u00a0 \u00a0 <\/em>\u00a0 Moderator: Leslie Gordon<\/td>\n<\/tr>\n
\u00a0 8:30-8:50 AM<\/td>\nAI-driven Therapeutic Antisense Oligonucleotide for HGPS<\/td>\nNing Shen, PhD
Professor
Liangzhu Laboratory, Zhejiang University School of Medicine<\/span><\/td>\n<\/tr>\n
\u00a0 8:55-9:15 AM<\/td>\nDevelopment of Gene Silencing (RNAi) and Gene Editing Therapeutics for Hutchinson-Gilford Progeria Syndrome (HGPS)<\/td>\nNizar Saad, PhD
Abigail Wexner Research Institute, Nationwide Children\u2019s Hospital\u00a0 <\/span><\/td>\n<\/tr>\n
\u00a0 9:20-9:45 AM<\/td>\nMini Plenary: Cutting Edge Translational Gene Therapy<\/td>\nDavid Liu, PhD
Thomas Dudley Cabot Professor of the Natural Sciences
Howard Hughes Medical Institute Investigator
Harvard University
Broad Institute<\/span>
<\/span><\/td>\n<\/tr>\n
\u00a09:50-10:10 AM<\/td>\nProSPER: PROgeria Streamlined Platform Gene Editing for Rare Diseases<\/td>\nDavid Liu
Francis Collins
Leslie Gordon
Meirui An, PhD, Broad Institute
Mike Erdos, PhD, NHGRI\u00a0<\/span><\/td>\n<\/tr>\n
\u00a010:15-10:35 AM<\/td>\nFirst-Generation PROTACs for Improving Progeria Phenotype<\/td>\nSilvia Ortega Gutierrez, PhD
Professor
Universidad Complutense de Madrid<\/span><\/td>\n<\/tr>\n
\u00a010:35-10:55 AM<\/td>\nBreak<\/strong><\/td>\n<\/td>\n<\/tr>\n
Endocrine and GI Disease in Progeria\u00a0 \u00a0 \u00a0 \u00a0<\/em>Moderator: Vicente Andr\u00e9s, PhD, Professor, Centro Nacional de Investigaciones Cardiovasculares Carlos III<\/td>\n<\/tr>\n
\u00a010:55-11:15 AM<\/td>\nLipodistrophy and Cardiovascular Pathology in HGPS<\/td>\nVicente Andr\u00e9s<\/td>\n<\/tr>\n
\u00a011:20-11:40 AM<\/td>\nUnraveling Accelerated Intestinal Ageing in HGPS Physiopathology: An Integrative Approach<\/td>\nLaurence Arbibe, MD, PhD
Director
INSERM\u00a0Institut Necker Enfants Malades<\/span><\/td>\n<\/tr>\n
\u00a011:45-12:05 PM<\/td>\nTargeting Inflammation to Ameliorate HGPS Pathologies<\/td>\nSusana Gonzalo, PhD
Professor
St. Louis University School of Medicine<\/span><\/td>\n<\/tr>\n
\u00a012:15-1:00 PM<\/td>\nWorkshop Summary Session All Hands Discussion<\/td>\nLeslie Gordon and Francis Collins<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/et_pb_text][et_pb_text disabled_on=”off|off|off” admin_label=”Workshop Committee” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

<\/strong><\/h3>\n

2025 PRF International Scientific Workshop Scientific Committee<\/span><\/h3>\n

Leslie B. Gordon, MD, PhD (Chair) <\/strong>– <\/strong>Medical Director, The Progeria Research Foundation; Professor of Pediatrics, Hasbro Children\u2019s Hospital, <\/em>Boston Children\u2019s Hospital, and Harvard Medical School\u00a0<\/em><\/p>\n

Vicente Andres, PhD <\/strong>– Professor, Centro Nacional de Investigaciones Cardiovasculares Carlos III<\/span><\/em><\/p>\n

Maria Eriksson, PhD<\/strong> – Professor, Karolinska Institute<\/em><\/p>\n

Mark Kieran, MD, PhD<\/strong> –\u00a0VP Clinical Development, Day One Biopharmaceuticals<\/em><\/p>\n

<\/span><\/strong><\/h3>\n

2025 PRF International Scientific Workshop Planning Committee<\/span><\/strong><\/h3>\n

Leslie B. Gordon, MD, PhD (Chair) –<\/strong> Medical Director, The Progeria Research Foundation; Professor of Pediatrics, Hasbro Children\u2019s Hospital, <\/em>Boston Children\u2019s Hospital, and Harvard Medical School\u00a0<\/em><\/p>\n

Audrey Gordon, Esq \u2013 <\/strong>President and Executive Director, The Progeria Research Foundation<\/em><\/p>\n

Gina Incrovato \u2013 <\/strong>Director of Operations, The Progeria Research Foundation<\/em>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0<\/em><\/p>\n

Darrien Marazzo \u2013<\/strong> Clinical Trial Coordinator, The Progeria Research Foundation\u00a0<\/em><\/p>\n

Karen Gordon Betournay\u2013 <\/em><\/strong>Social Media and Website Coordinator,<\/em>\u00a0The Progeria Research Foundation<\/em><\/p>\n

Elizabeth Maynard <\/strong>\u2013 Elizabeth Maynard, CMP, Meeting Planner<\/span>, Etre Partners<\/a><\/em><\/p>\n

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  Agenda at a Glance Note: Agenda Subject to Change Wednesday, October 29, 2025 Time Session Speaker \u00a0 3:00-5:00 PM \u00a0 Registration & Poster Set-Up \u00a0 5:00-5:15 PM \u00a0 Introduction & Greetings from PRF Audrey Gordon, Esq.Executive DirectorThe Progeria Research Foundation Scott Berns, MD, MPH, FAAPBoard ChairThe Progeria Research Foundation Leslie Gordon, MD, PhDMedical DirectorThe […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-19982","page","type-page","status-publish","hentry"],"yoast_head":"\nAgenda | The Progeria Research Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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