{"id":763,"date":"2017-02-25T22:17:39","date_gmt":"2017-02-25T22:17:39","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?page_id=763"},"modified":"2024-06-20T11:31:51","modified_gmt":"2024-06-20T15:31:51","slug":"progeria-101faq","status":"publish","type":"page","link":"https:\/\/www.progeriaresearch.org\/kk\/progeria-101faq\/","title":{"rendered":"Progeria 101\/\u0416\u049a\u0421"},"content":{"rendered":"<p>[et_pb_section fb_built=\u201d1\u2033 fullwidth=\u201don\u201d disabled_on=\u201doff|off|off\u201d _builder_version=\u201d4.16\u2033 border_width_bottom=\u201d55px\u201d border_color_bottom=\u201d#29327a\u201d global_colors_info=\u201d{p}b _builder_version=\u201d4.16\u2033 title_font_size=\u201d55\u2033 background_color=\u201d#29327a\u201d background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/About-Header_position\u201d background_position\u201djp custom_padding=\u201d11.5vw||11.5vw||true\u201d custom_padding_tablet=\u201d\u201d custom_padding_phone=\u201d|56px||\u201d custom_padding_last_edited=\u201don|desktop\u201d title_font_size_tablet=\u201d45px\u201d title_font_size_phone=\u201d40px\u201d title_font_size_last_edited=\u201don|phone\u201d z_index_tablet=\u201d500\u2033 custom_css_main_round=\u201dTPCenter=\u201dbackg18- !\u043c\u0430\u04a3\u044b\u0437\u0434\u044b;\u201d global_colors_info=\u201d{}\u201d]<\/p>\n<h1>Progeria 101 \/ \u0416\u0438\u0456 \u049b\u043e\u0439\u044b\u043b\u0430\u0442\u044b\u043d \u0441\u04b1\u0440\u0430\u049b\u0442\u0430\u0440<\/h1>\n<p>[\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=\u201d1\u2033 use_custom_gutter=\u201don\u201d gutter_width=\u201d1\u2033 specialty=\u201don\u201d padding_left_1=\u201d35px\u201d padding_left_2=\u201d35px\u201d padding_left_2=\u201dpxding_\u201d0\u201d|\u201d| padding_2_phone=\u201d|||0px\u201d padding_2_last_edited=\u201d|\u0436\u04b1\u043c\u044b\u0441 \u04af\u0441\u0442\u0435\u043b\u0456\u043d\u0434\u0435\u201d module_class_1=\u201dsidebar-secondary-nav\u201d module_class=\u201dhandprint-bg\u201d _builder_version=\u201d4.16\u2033 background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/blue-handprint-only.png\u201d parallax=\u201don\u201d parallax_method=\u201doff\u201d inner_width=\u201d100%\u201d inner_max_width=\u201d100% \u00bb custom_padding=\u201d0|0px|54px|0px|false|false\u201d z_index_tablet=\u201d500\u2033 border_width_top=\u201d10px\u201d border_color_top=\u201d#8fd2ed\u201d use_custom_width=\u201don\u201d width_unit=\u201doff\u201d custom_width_percent=\u201dTP10 global_colors_info=\u201d{}\u201d][et_pb_column type=\u201d1_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_sidebar area=\u201det_pb_widget_area_18\u2033 disabled_on=\u201don|on|off\u201d module_class=\u201dsubpage-sidebars\u201d _builder_version=\u201d4.16\u2033style=\u201dfacebar z_index_tablet=\u201d500\u2033 border_width_right=\u201d5px\u201d global_colors_info=\u201d{}\u201d]<\/p>\n<p>[\/et_pb_sidebar][\/et_pb_column][et_pb_column type=\u201d3_4\u2033 specialty_columns=\u201d3\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_row_inner custom_padding_last_edited=\u201don|phone\u201d _builder_version=\u201d4.16\u2033 custom_padding=\u201d0px|35px|35px||false|false\u201dpx|35px|3\u201d custom_padding_padding|5|3\u201d ||\u0448\u044b\u043d\u00bb custom_padding_phone=\u201d\u201d animation_direction=\u201dtop\u201d global_colors_info=\u201d{}\u201d][et_pb_column_inner saved_specialty_column_type=\u201d3_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_toggle title=\u201d\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0434\u0435\u0433\u0435\u043d\u0456\u043c\u0456\u0437 \u043d\u0435?\u201d open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;Progeria \u0434\u0435\u0433\u0435\u043d\u0456\u043c\u0456\u0437 \u043d\u0435?&quot; module_id=\u201d\u0441\u0456\u043b\u0442\u0435\u043c\u0435\u043b\u0435\u0440\u201d _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding=\u201d|animation||true\u201d custom_padding=\u201d|animation|50px|detr|5\u201d animation_direction=\u201d\u0436\u043e\u0493\u0430\u0440\u044b\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d title_font_size_tablet=\u201d\u201d title_font_size_phone=\u201d28px\u201d title_font_size_last_edited=\u201dz&amp;quot;x_0\u201dz&amp;t;x_0\u201dzv| border_width_all=\u201d0px\u201d global_colors_info=\u201d{}\u201d]<\/p>\n<div class=\"vc_tta-panel-heading\">\n<p>\u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b (HGPS \u043d\u0435\u043c\u0435\u0441\u0435 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f) \u2013 \u04e9\u0442\u0435 \u0441\u0438\u0440\u0435\u043a \u043a\u0435\u0437\u0434\u0435\u0441\u0435\u0442\u0456\u043d, \u04e9\u043b\u0456\u043c\u043c\u0435\u043d \u0430\u044f\u049b\u0442\u0430\u043b\u0430\u0442\u044b\u043d, \u00ab\u0442\u0435\u0437 \u049b\u0430\u0440\u0442\u0430\u044e\u00bb \u0430\u0443\u0440\u0443\u044b. \u041e\u043d\u044b\u04a3 \u0430\u0442\u0430\u0443\u044b \u0433\u0440\u0435\u043a \u0442\u0456\u043b\u0456\u043d\u0435\u043d \u0448\u044b\u049b\u049b\u0430\u043d \u0436\u04d9\u043d\u0435 \u00ab\u0435\u0440\u0442\u0435 \u0435\u0441\u043a\u0456\u00bb \u0434\u0435\u0433\u0435\u043d\u0434\u0456 \u0431\u0456\u043b\u0434\u0456\u0440\u0435\u0434\u0456. \u041a\u043b\u0430\u0441\u0441\u0438\u043a\u0430\u043b\u044b\u049b \u0442\u04af\u0440\u0456 - \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b, \u043e\u043d\u044b \u0430\u043b\u0493\u0430\u0448 \u0441\u0438\u043f\u0430\u0442\u0442\u0430\u0493\u0430\u043d \u0434\u04d9\u0440\u0456\u0433\u0435\u0440\u043b\u0435\u0440\u0434\u0456\u04a3 \u0430\u0442\u044b\u043c\u0435\u043d \u0430\u0442\u0430\u043b\u0434\u044b: 1886 \u0436\u044b\u043b\u044b \u0434\u043e\u043a\u0442\u043e\u0440 \u0414\u0436\u043e\u043d\u0430\u0442\u0430\u043d \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d \u0436\u04d9\u043d\u0435 1897 \u0436\u044b\u043b\u044b \u0434\u043e\u043a\u0442\u043e\u0440 \u0425\u0430\u0441\u0442\u0438\u043d\u0433\u0441 \u0413\u0438\u043b\u0444\u043e\u0440\u0434.<a href=\"#referencefour\">.[1]<\/a><\/p>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;Progeria \u049b\u0430\u043d\u0448\u0430\u043b\u044b\u049b\u0442\u044b \u0436\u0438\u0456 \u043a\u0435\u0437\u0434\u0435\u0441\u0435\u0434\u0456?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;Progeria \u049b\u0430\u043d\u0448\u0430\u043b\u044b\u049b\u0442\u044b \u0436\u0438\u0456 \u043a\u0435\u0437\u0434\u0435\u0441\u0435\u0434\u0456?&quot; module_id=\u201d#ftn2\u2033 _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding=|tr|5\u201d animation_style=\u201dslide\u201d animation_direction=\u201dtop\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d z_index_tablet=\u201d500\u2033 border_width_all=\u201d0px\u201d global_colors_info=\u201d{}\u201d]<\/p>\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p>\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0448\u0430\u043c\u0430\u043c\u0435\u043d 4-8 \u043c\u0438\u043b\u043b\u0438\u043e\u043d \u0436\u0430\u04a3\u0430 \u0442\u0443\u0493\u0430\u043d \u043d\u04d9\u0440\u0435\u0441\u0442\u0435\u043d\u0456\u04a3 1-\u0456\u043d\u0434\u0435 \u043a\u0435\u0437\u0434\u0435\u0441\u0435\u0434\u0456, \u0431\u04b1\u043b \u0435\u043a\u0456 \u0436\u044b\u043d\u044b\u0441\u049b\u0430 \u0434\u0430, \u0431\u0430\u0440\u043b\u044b\u049b \u043d\u04d9\u0441\u0456\u043b\u0434\u0435\u0440\u0433\u0435 \u0434\u0435 \u0431\u0456\u0440\u0434\u0435\u0439 \u04d9\u0441\u0435\u0440 \u0435\u0442\u0435\u0434\u0456. \u0422\u0456\u0440\u0456 18-20 \u043c\u0438\u043b\u043b\u0438\u043e\u043d \u0430\u0434\u0430\u043c\u043d\u044b\u04a3 \u0431\u0456\u0440\u0456\u043d\u0434\u0435 \u043a\u043b\u0430\u0441\u0441\u0438\u043a\u0430\u043b\u044b\u049b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0431\u0430\u0440 \u0436\u04d9\u043d\u0435 \u0434\u04af\u043d\u0438\u0435 \u0436\u04af\u0437\u0456\u043d\u0434\u0435 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043c\u0435\u043d \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0435\u0442\u0456\u043d \u0448\u0430\u043c\u0430\u043c\u0435\u043d 400 \u0431\u0430\u043b\u0430 \u0431\u0430\u0440. Progeria Research Foundation (PRF) 1999 \u0436\u044b\u043b\u044b \u049b\u04b1\u0440\u044b\u043b\u0493\u0430\u043d\u043d\u0430\u043d \u0431\u0435\u0440\u0456 \u0431\u0456\u0437 72 \u0435\u043b\u0434\u0435 \u0436\u04d9\u043d\u0435 \u0431\u0430\u0440\u043b\u044b\u049b \u043a\u043e\u043d\u0442\u0438\u043d\u0435\u043d\u0442\u0442\u0435\u0440\u0434\u0435 \u0442\u04b1\u0440\u0430\u0442\u044b\u043d \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0434\u044b \u0442\u0430\u0443\u044b\u043f, \u043e\u043b\u0430\u0440\u0493\u0430 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0442\u0456\u043a.<a href=\"#referencefour\" name=\"_ftnref1\">[2]<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;Progeria \u043c\u04af\u043c\u043a\u0456\u043d\u0434\u0456\u043a\u0442\u0435\u0440\u0456 \u049b\u0430\u043d\u0434\u0430\u0439?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;Progeria \u043c\u04af\u043c\u043a\u0456\u043d\u0434\u0456\u043a\u0442\u0435\u0440\u0456 \u049b\u0430\u043d\u0434\u0430\u0439?&quot; _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding=\u201d|50px||50px||true\u201d animation=toplion\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all=\u201d0px\u201d global_colors_info=\u201d{}\u201d sticky_enabled=\u201d0<\/p>\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<div class=\"vc_tta-panel-heading\">\n<p>\u04d8\u0434\u0435\u0442\u0442\u0435 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\u0436\u04d9\u043d\u0435\/\u043d\u0435\u043c\u0435\u0441\u0435 \u0436\u0430\u043c\u0431\u0430\u0441 \u0430\u0439\u043c\u0430\u0493\u044b\u043d\u0434\u0430\u0493\u044b \u0442\u0435\u0440\u0456\u043d\u0456\u04a3 \u0442\u0430\u0440\u044b\u043b\u0443\u044b \u043d\u0435\u043c\u0435\u0441\u0435 \u0434\u04e9\u04a3\u0435\u0441 \u0431\u043e\u043b\u0443\u044b \u0436\u04d9\u043d\u0435 \u0434\u0430\u043c\u044b\u043f \u043a\u0435\u0442\u043f\u0435\u0443\u0456 (\u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u04e9\u0441\u0443 \u049b\u0438\u0441\u044b\u0493\u044b\u043d\u0430\u043d \u0431\u0456\u0440\u0448\u0430\u043c\u0430 \u0442\u04e9\u043c\u0435\u043d \u0442\u04af\u0441\u0443\u0456) \u0431\u043e\u043b\u044b\u043f \u0442\u0430\u0431\u044b\u043b\u0430\u0434\u044b. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u0431\u0430\u0441\u049b\u0430 \u0435\u0440\u0442\u0435 \u0431\u0435\u043b\u0433\u0456\u043b\u0435\u0440\u0456\u043d\u0435 \u0434\u0435\u043d\u0435 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\u044d\u0442\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0442\u043e\u043f\u0442\u0430\u0440\u044b \u04d9\u0440\u0442\u04af\u0440\u043b\u0456 \u0431\u043e\u043b\u0493\u0430\u043d\u044b\u043c\u0435\u043d, \u0441\u044b\u0440\u0442\u049b\u044b \u043a\u0435\u043b\u0431\u0435\u0442\u0456 \u04e9\u0442\u0435 \u04b1\u049b\u0441\u0430\u0441. \u0411\u0430\u043b\u0430\u043b\u0430\u0440 \u0435\u0441\u0435\u0439\u0433\u0435\u043d \u0441\u0430\u0439\u044b\u043d \u043e\u043b\u0430\u0440\u0434\u0430 \u0436\u0435\u0434\u0435\u043b \u0430\u0442\u0435\u0440\u043e\u0441\u043a\u043b\u0435\u0440\u043e\u0437 \u0436\u04d9\u043d\u0435 \u0436\u04af\u0440\u0435\u043a-\u049b\u0430\u043d \u0442\u0430\u043c\u044b\u0440\u043b\u0430\u0440\u044b (\u0436\u04af\u0440\u0435\u043a) \u0430\u0443\u0440\u0443\u043b\u0430\u0440\u044b \u0434\u0430\u043c\u0438\u0434\u044b. \u0411\u04b1\u043b \u04d9\u0434\u0435\u0442\u0442\u0435 60 \u0436\u04d9\u043d\u0435 \u043e\u0434\u0430\u043d \u0436\u043e\u0493\u0430\u0440\u044b \u0436\u0430\u0441\u0442\u0430\u0493\u044b \u0430\u0434\u0430\u043c\u0434\u0430\u0440\u0493\u0430 \u04d9\u0441\u0435\u0440 \u0435\u0442\u0435\u0442\u0456\u043d \u0430\u0442\u0435\u0440\u043e\u0441\u043a\u043b\u0435\u0440\u043e\u0437, \u0431\u0456\u0440\u0430\u049b \u043e\u043b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043c\u0435\u043d \u0430\u0443\u044b\u0440\u0430\u0442\u044b\u043d\u0434\u0430\u0440\u0493\u0430 \u04d9\u043b\u0434\u0435\u049b\u0430\u0439\u0434\u0430 \u0435\u0440\u0442\u0435 \u0436\u04d9\u043d\u0435 \u0436\u044b\u043b\u0434\u0430\u043c \u04d9\u0441\u0435\u0440 \u0435\u0442\u0435\u0434\u0456.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u0441\u0435\u0431\u0435\u0431\u0456 \u043d\u0435\u0434\u0435?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u0441\u0435\u0431\u0435\u0431\u0456 \u043d\u0435\u0434\u0435?&quot; module_id=\u201d#ftn8\u2033 _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding||5px|\u201d0 animation_style=\u201dslide\u201d animation_direction=\u201dtop\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all_color=\u201dglobalcolors=\u201dpx sticky_enabled=\u201d0\u2033]<\/p>\n<div class=\"wp-caption alignnone\">\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.progeriaresearch.org\/assets\/images\/medical_images\/progeria-cell.jpg\" alt=\"\" width=\"142\" height=\"115\" \/><br \/><strong>\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0436\u0430\u0441\u0443\u0448\u0430\u0441\u044b\u043d\u044b\u04a3 \u044f\u0434\u0440\u043e\u0441\u044b<\/strong><\/p>\n<\/div>\n<p>PRF \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u043a\u043e\u043d\u0441\u043e\u0440\u0446\u0438\u0443\u043c\u044b\u043d\u044b\u04a3 \u0436\u0435\u0442\u0435\u043a\u0448\u0456 \u0493\u0430\u043b\u044b\u043c\u0434\u0430\u0440\u044b \u0442\u043e\u0431\u044b, \u043e\u043d\u044b\u04a3 \u0456\u0448\u0456\u043d\u0434\u0435 \u0430\u0434\u0430\u043c \u0433\u0435\u043d\u043e\u043c\u044b\u043d\u044b\u04a3 \u04b1\u043b\u0442\u0442\u044b\u049b \u0437\u0435\u0440\u0442\u0442\u0435\u0443 \u0438\u043d\u0441\u0442\u0438\u0442\u0443\u0442\u044b\u043d\u044b\u04a3 \u0441\u043e\u043b \u043a\u0435\u0437\u0434\u0435\u0433\u0456 \u0434\u0438\u0440\u0435\u043a\u0442\u043e\u0440\u044b \u0434\u043e\u043a\u0442\u043e\u0440 \u0424\u0440\u044d\u043d\u0441\u0438\u0441 \u041a\u043e\u043b\u043b\u0438\u043d\u0437 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0433\u0435\u043d\u0456\u043d \u0431\u04e9\u043b\u0456\u043f \u0430\u043b\u0434\u044b. 2003 \u0436\u044b\u043b\u0434\u044b\u04a3 \u0441\u04d9\u0443\u0456\u0440 \u0430\u0439\u044b\u043d\u0434\u0430 \u041a\u043e\u043d\u0441\u043e\u0440\u0446\u0438\u0443\u043c \u0431\u04b1\u043b \u0442\u04b1\u0436\u044b\u0440\u044b\u043c\u0434\u044b \u0435\u04a3 \u0431\u0430\u0441\u0442\u044b \u0493\u044b\u043b\u044b\u043c\u0438 \u0436\u0443\u0440\u043d\u0430\u043b\u0434\u0430 \u0445\u0430\u0431\u0430\u0440\u043b\u0430\u0434\u044b <em>\u0422\u0430\u0431\u0438\u0493\u0430\u0442.<a href=\"#referencefour\" name=\"_ftnref1\">[3]<\/a><\/em><\/p>\n<p style=\"padding-left: 40px;\"><em>\u00ab\u041e\u049b\u0448\u0430\u0443\u043b\u0430\u0443<\/em> <em>the<\/em> <em>\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f<\/em> <em>\u0433\u0435\u043d<\/em> <em>\u0431\u043e\u043b\u044b\u043f \u0442\u0430\u0431\u044b\u043b\u0430\u0434\u044b<\/em> <em>\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430\u043b\u044b\u049b \u0437\u0435\u0440\u0442\u0442\u0435\u0443 \u049b\u0430\u0443\u044b\u043c\u0434\u0430\u0441\u0442\u044b\u0493\u044b \u04af\u0448\u0456\u043d \u04af\u043b\u043a\u0435\u043d \u0436\u0435\u0442\u0456\u0441\u0442\u0456\u043a \u00bb <\/em>- \u0434\u0435\u0434\u0456 \u0434\u043e\u043a\u0442\u043e\u0440 \u0424\u0440\u044d\u043d\u0441\u0438\u0441 \u041a\u043e\u043b\u043b\u0438\u043d\u0437, Progeria \u0433\u0435\u043d\u0434\u0456\u043a \u043c\u0443\u0442\u0430\u0446\u0438\u044f \u0442\u0443\u0440\u0430\u043b\u044b \u0435\u0441\u0435\u043f\u0442\u0456\u04a3 \u0430\u0493\u0430 \u0430\u0432\u0442\u043e\u0440\u044b. \u00ab<em>\u0411\u04b1\u043b \u0436\u0430\u04a3\u0430\u043b\u044b\u049b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0434\u0430\u043d \u0437\u0430\u0440\u0434\u0430\u043f \u0448\u0435\u043a\u043a\u0435\u043d \u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u043c\u0435\u043d \u043e\u0442\u0431\u0430\u0441\u044b\u043b\u0430\u0440\u0493\u0430 \u04af\u043c\u0456\u0442 \u0431\u0435\u0440\u0456\u043f \u049b\u0430\u043d\u0430 \u049b\u043e\u0439\u043c\u0430\u0439\u0434\u044b, \u0441\u043e\u043d\u044b\u043c\u0435\u043d \u049b\u0430\u0442\u0430\u0440 \u049b\u0430\u0440\u0442\u0430\u044e \u0436\u04d9\u043d\u0435 \u0436\u04af\u0440\u0435\u043a-\u0442\u0430\u043c\u044b\u0440 \u0430\u0443\u0440\u0443\u043b\u0430\u0440\u044b \u0444\u0435\u043d\u043e\u043c\u0435\u043d\u0456\u043d\u0435 \u0436\u0430\u0440\u044b\u049b \u0442\u04af\u0441\u0456\u0440\u0443\u0456 \u043c\u04af\u043c\u043a\u0456\u043d\u00bb.<\/em><\/p>\n<p>Progeria \u0433\u0435\u043d\u0456\u043d\u0456\u04a3 \u0430\u0448\u044b\u043b\u0443\u044b Progeria \u0434\u0435\u043f \u0430\u0442\u0430\u043b\u0430\u0442\u044b\u043d \u0433\u0435\u043d\u043d\u0456\u04a3 \u043c\u0443\u0442\u0430\u0446\u0438\u044f\u0441\u044b\u043d\u0430\u043d \u0442\u0443\u044b\u043d\u0434\u0430\u0493\u0430\u043d\u044b\u043d \u0430\u043d\u044b\u049b\u0442\u0430\u0434\u044b <em>LMNA <\/em>(\u00ablamin-A\u00bb \u0434\u0435\u043f \u0430\u0439\u0442\u044b\u043b\u0430\u0434\u044b). The <em>LMNA <\/em>\u0433\u0435\u043d \u0436\u0430\u0441\u0443\u0448\u0430\u043d\u044b\u04a3 \u044f\u0434\u0440\u043e\u0441\u044b\u043d \u0431\u0456\u0440\u0433\u0435 \u04b1\u0441\u0442\u0430\u0439\u0442\u044b\u043d \u0436\u04d9\u043d\u0435 \u0436\u0430\u0441\u0443\u0448\u0430\u043b\u0430\u0440\u0434\u044b\u04a3 \u0441\u0430\u0443 \u0431\u043e\u043b\u0443\u044b\u043d\u0430 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435\u0442\u0456\u043d \u049b\u04b1\u0440\u044b\u043b\u044b\u043c\u0434\u044b\u049b \u0442\u0456\u0440\u0435\u043a \u0431\u04e9\u043b\u0456\u0433\u0456 \u0431\u043e\u043b\u044b\u043f \u0442\u0430\u0431\u044b\u043b\u0430\u0442\u044b\u043d \u043b\u0430\u043c\u0438\u043d \u0410 \u0430\u049b\u0443\u044b\u0437\u044b\u043d \u0448\u044b\u0493\u0430\u0440\u0430\u0434\u044b. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b \u0442\u0443\u0434\u044b\u0440\u0430\u0442\u044b\u043d \u0430\u043d\u043e\u0440\u043c\u0430\u043b\u044c\u0434\u044b \u043b\u0430\u043c\u0438\u043d \u0430\u049b\u0443\u044b\u0437\u044b \u0434\u0435\u043f \u0430\u0442\u0430\u043b\u0430\u0434\u044b <strong><em>\u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d<\/em><\/strong>. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u0436\u0430\u0441\u0443\u0448\u0430\u043b\u0430\u0440\u0434\u044b \u0442\u04b1\u0440\u0430\u049b\u0441\u044b\u0437 \u0435\u0442\u0435\u0434\u0456, \u0431\u04b1\u043b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u0435\u0440\u0442\u0435 \u049b\u0430\u0440\u0442\u0430\u044e\u044b\u043d\u0430 \u0436\u04d9\u043d\u0435 \u0430\u0443\u0440\u0443\u044b\u043d\u0430 \u04d9\u043a\u0435\u043b\u0435\u0434\u0456.<\/p>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u049b\u0430\u0440\u0442\u0430\u044e\u0493\u0430 \u049b\u0430\u043d\u0434\u0430\u0439 \u049b\u0430\u0442\u044b\u0441\u044b \u0431\u0430\u0440?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u049b\u0430\u0440\u0442\u0430\u044e\u0493\u0430 \u049b\u0430\u043d\u0434\u0430\u0439 \u049b\u0430\u0442\u044b\u0441\u044b \u0431\u0430\u0440?&quot; module_id=\u201d#ftn8\u2033 _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding||5px|\u201d0 animation_style=\u201dslide\u201d animation_direction=\u201dtop\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all_color=\u201dglobalcolors=\u201dpx sticky_enabled=\u201d0\u2033]<\/p>\n<div id=\"1488059409784-71ca0fef-3046\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<p>\u049a\u0430\u0440\u0442\u0430\u044e \u043f\u0440\u043e\u0446\u0435\u0441\u0456\u043d\u0456\u04a3 \u0435\u04a3 \u049b\u044b\u0437\u044b\u049b\u0442\u044b \u0430\u043d\u044b\u049b\u0442\u0430\u043c\u0430\u0441\u044b - \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u043f\u0440\u043e\u0442\u0435\u0438\u043d\u0456 \u049b\u0430\u0440\u0442\u0430\u044e \u043a\u0435\u0437\u0456\u043d\u0434\u0435 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0434\u0430 \u0434\u0430, \u049b\u0430\u043b\u044b\u043f\u0442\u044b \u0436\u0430\u0441\u0443\u0448\u0430\u043b\u0430\u0440\u0434\u0430 \u0434\u0430 \u0436\u043e\u0493\u0430\u0440\u044b \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u044f\u0434\u0430 \u0431\u043e\u043b\u0430\u0442\u044b\u043d\u044b\u043d \u0430\u0448\u0443. \u0411\u0456\u0437\u0434\u0456\u04a3 \u0434\u0435\u043d\u0435\u043c\u0456\u0437 \u0436\u04af\u0440\u0435\u043a-\u049b\u0430\u043d\u0442\u0430\u043c\u044b\u0440 \u0436\u04af\u0439\u0435\u0441\u0456\u043d\u0456\u04a3 \u0436\u0430\u0441\u0443\u0448\u0430\u043b\u0430\u0440\u044b\u043d\u0434\u0430 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d\u0434\u0456 \u0436\u044b\u043b \u0441\u0430\u0439\u044b\u043d \u0448\u0430\u043c\u0430\u043c\u0435\u043d 3% (\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u043c\u0435\u043d \u0436\u0430\u0441\u04e9\u0441\u043f\u0456\u0440\u0456\u043c\u0434\u0435\u0440\u0433\u0435 \u049b\u0430\u0440\u0430\u0493\u0430\u043d\u0434\u0430 \u04d9\u043b\u0434\u0435\u049b\u0430\u0439\u0434\u0430 \u0442\u04e9\u043c\u0435\u043d) \u0436\u0438\u043d\u0430\u0439\u0434\u044b. \u041e\u0441\u044b\u043b\u0430\u0439\u0448\u0430, Progeria-\u043d\u044b \u0442\u04af\u0441\u0456\u043d\u0443 \u0442\u0430\u0431\u0438\u0493\u0438 \u049b\u0430\u0440\u0442\u0430\u044e \u043f\u0440\u043e\u0446\u0435\u0441\u0456\u043d \u0442\u04af\u0441\u0456\u043d\u0443\u0434\u0456\u04a3 \u0436\u0430\u04a3\u0430 \u0436\u043e\u043b\u0434\u0430\u0440\u044b\u043d \u0443\u04d9\u0434\u0435 \u0435\u0442\u0435\u0434\u0456.<\/p>\n<p>\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u0435\u0440\u0442\u0435, \u04af\u0434\u0435\u043c\u0435\u043b\u0456 \u0436\u04af\u0440\u0435\u043a \u0430\u0443\u0440\u0443\u044b\u043d\u0430 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u0431\u0435\u0439\u0456\u043c. \u04e8\u043b\u0456\u043c \u0434\u0435\u0440\u043b\u0456\u043a \u0442\u0435\u043a \u049b\u0430\u043d\u0430 \u043a\u0435\u04a3 \u0442\u0430\u0440\u0430\u043b\u0493\u0430\u043d\u0434\u044b\u049b\u0442\u0430\u043d \u043e\u0440\u044b\u043d \u0430\u043b\u0430\u0434\u044b <strong>\u0436\u04af\u0440\u0435\u043a \u0430\u0443\u0440\u0443\u044b, \u0434\u04af\u043d\u0438\u0435 \u0436\u04af\u0437\u0456\u043d\u0434\u0435 \u04e9\u043b\u0456\u043c\u043d\u0456\u04a3 \u0431\u0430\u0441\u0442\u044b \u0441\u0435\u0431\u0435\u0431\u0456<\/strong>.<a href=\"#referencefour\" name=\"_ftnref1\">[4]<\/a> \u041e\u0441\u044b\u043b\u0430\u0439\u0448\u0430, \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0434\u0430 \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u0433\u0435 \u04af\u043b\u043a\u0435\u043d \u049b\u0430\u0436\u0435\u0442\u0442\u0456\u043b\u0456\u043a \u0431\u0430\u0440 \u0435\u043a\u0435\u043d\u0456 \u0430\u043d\u044b\u049b. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u0435\u043c\u0456\u043d \u0442\u0430\u0431\u0443 \u0442\u0435\u043a \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043c\u0435\u043d \u0430\u0443\u044b\u0440\u0430\u0442\u044b\u043d\u0434\u0430\u0440\u0493\u0430 \u0493\u0430\u043d\u0430 \u0435\u043c\u0435\u0441, \u0441\u043e\u043d\u044b\u043c\u0435\u043d \u0431\u0456\u0440\u0433\u0435 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435\u0434\u0456<strong> \u0421\u043e\u043d\u0434\u0430\u0439-\u0430\u049b \u0436\u04af\u0440\u0435\u043a \u0430\u0443\u0440\u0443\u044b \u043c\u0435\u043d \u0438\u043d\u0441\u0443\u043b\u044c\u0442\u043f\u0435\u043d \u0430\u0443\u044b\u0440\u0430\u0442\u044b\u043d \u043c\u0438\u043b\u043b\u0438\u043e\u043d\u0434\u0430\u0493\u0430\u043d \u0435\u0440\u0435\u0441\u0435\u043a\u0442\u0435\u0440\u0434\u0456 \u0435\u043c\u0434\u0435\u0443\u0433\u0435 \u0430\u0440\u043d\u0430\u043b\u0493\u0430\u043d \u043a\u0435\u04a3\u0435\u0441\u0442\u0435\u0440 \u0431\u0435\u0440\u0435 \u0430\u043b\u0430\u0434\u044b <\/strong>\u0442\u0430\u0431\u0438\u0493\u0438 \u049b\u0430\u0440\u0442\u0430\u044e \u043f\u0440\u043e\u0446\u0435\u0441\u0456\u043c\u0435\u043d \u0431\u0430\u0439\u043b\u0430\u043d\u044b\u0441\u0442\u044b<strong>.<\/strong><\/p>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0430\u0442\u0430-\u0430\u043d\u0430\u0434\u0430\u043d \u0431\u0430\u043b\u0430\u0493\u0430 \u0431\u0435\u0440\u0456\u043b\u0456\u043f \u0436\u0430\u0442\u044b\u0440 \u043c\u0430?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0430\u0442\u0430-\u0430\u043d\u0430\u0434\u0430\u043d \u0431\u0430\u043b\u0430\u0493\u0430 \u0431\u0435\u0440\u0456\u043b\u0435\u0434\u0456 \u043c\u0435?&quot; _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding=\u201d|50px||50px||true\u201d animation=toplion\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all=\u201d0px\u201d global_colors_info=\u201d{}\u201d sticky_enabled=\u201d0<\/p>\n<div id=\"1488059409784-71ca0fef-3046\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-heading\">\n<p>HGPS \u04d9\u0434\u0435\u0442\u0442\u0435 \u043e\u0442\u0431\u0430\u0441\u044b\u043b\u0430\u0440\u0434\u0430 \u0431\u0435\u0440\u0456\u043b\u043c\u0435\u0439\u0434\u0456. \u0413\u0435\u043d\u043d\u0456\u04a3 \u04e9\u0437\u0433\u0435\u0440\u0443\u0456 \u04d9\u0440\u049b\u0430\u0448\u0430\u043d \u04e9\u0442\u0435 \u0441\u0438\u0440\u0435\u043a \u043a\u0435\u0437\u0434\u0435\u0441\u0435\u0442\u0456\u043d \u043a\u0435\u0437\u0434\u0435\u0439\u0441\u043e\u049b \u043e\u049b\u0438\u0493\u0430 \u0431\u043e\u043b\u044b\u043f \u0442\u0430\u0431\u044b\u043b\u0430\u0434\u044b. HGPS \u0435\u043c\u0435\u0441 \u00ab\u043f\u0440\u043e\u0433\u0435\u0440\u043e\u0438\u0434\u0442\u044b\u00bb \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u043d\u044b\u04a3 \u0431\u0430\u0441\u049b\u0430 \u0442\u04af\u0440\u043b\u0435\u0440\u0456 \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0434\u0430 \u043e\u0442\u0431\u0430\u0441\u044b\u043d\u0434\u0430 \u0431\u0435\u0440\u0456\u043b\u0435\u0442\u0456\u043d \u0430\u0443\u0440\u0443\u043b\u0430\u0440 \u0431\u043e\u043b\u0443\u044b \u043c\u04af\u043c\u043a\u0456\u043d. \u0414\u0435\u0433\u0435\u043d\u043c\u0435\u043d, HGPS - \u0431\u04b1\u043b \u00ab\u0441\u043f\u043e\u0440\u0430\u0434\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0430\u0432\u0442\u043e\u0441\u043e\u043c\u0434\u044b-\u0434\u043e\u043c\u0438\u043d\u0430\u043d\u0442\u0442\u044b\u00bb \u043c\u0443\u0442\u0430\u0446\u0438\u044f \u2013 \u0441\u043f\u043e\u0440\u0430\u0434\u0438\u043a\u0430\u043b\u044b\u049b, \u04e9\u0439\u0442\u043a\u0435\u043d\u0456 \u0431\u04b1\u043b \u043e\u0441\u044b \u043e\u0442\u0431\u0430\u0441\u044b\u043d\u0434\u0430 \u0436\u0430\u04a3\u0430 \u04e9\u0437\u0433\u0435\u0440\u0456\u0441 \u0436\u04d9\u043d\u0435 \u0434\u043e\u043c\u0438\u043d\u0430\u043d\u0442\u0442\u044b, \u04e9\u0439\u0442\u043a\u0435\u043d\u0456 \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u043d\u044b\u04a3 \u0431\u043e\u043b\u0443\u044b \u04af\u0448\u0456\u043d \u0433\u0435\u043d\u043d\u0456\u04a3 \u0442\u0435\u043a \u0431\u0456\u0440 \u043a\u04e9\u0448\u0456\u0440\u043c\u0435\u0441\u0456\u043d \u04e9\u0437\u0433\u0435\u0440\u0442\u0443 \u049b\u0430\u0436\u0435\u0442. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u0441\u044b \u0431\u043e\u043b\u043c\u0430\u0493\u0430\u043d \u0430\u0442\u0430-\u0430\u043d\u0430\u043b\u0430\u0440 \u04af\u0448\u0456\u043d \u0431\u04b1\u043b \u043c\u04af\u043c\u043a\u0456\u043d\u0434\u0456\u043a 4-8 \u043c\u0438\u043b\u043b\u0438\u043e\u043d\u043d\u0430\u043d \u0431\u0456\u0440. \u0411\u0456\u0440\u0430\u049b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u0441\u044b \u0431\u0430\u0440 \u0430\u0442\u0430-\u0430\u043d\u0430\u043b\u0430\u0440 \u04af\u0448\u0456\u043d \u0431\u04b1\u043b \u0430\u0442\u0430-\u0430\u043d\u0430\u043b\u0430\u0440\u043c\u0435\u043d \u049b\u0430\u0439\u0442\u0430\u043b\u0430\u043d\u0443 \u044b\u049b\u0442\u0438\u043c\u0430\u043b\u0434\u044b\u0493\u044b \u04d9\u043b\u0434\u0435\u049b\u0430\u0439\u0434\u0430 \u0436\u043e\u0493\u0430\u0440\u044b - \u0448\u0430\u043c\u0430\u043c\u0435\u043d 2-3%. \u041d\u0435\u043b\u0456\u043a\u0442\u0435\u043d \u04e9\u0441\u0456\u043c? \u0411\u04b1\u043b \u0430\u0442\u0430-\u0430\u043d\u0430\u0441\u044b\u043d\u044b\u04a3 \u0436\u0430\u0441\u0443\u0448\u0430\u043b\u0430\u0440\u044b\u043d\u044b\u04a3 \u0430\u0437 \u0431\u04e9\u043b\u0456\u0433\u0456\u043d\u0434\u0435 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u04af\u0448\u0456\u043d \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u043c\u0443\u0442\u0430\u0446\u0438\u044f \u0431\u0430\u0440, \u0431\u0456\u0440\u0430\u049b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0436\u043e\u049b \u0431\u043e\u043b\u0430\u0442\u044b\u043d \u00ab\u043c\u043e\u0437\u0430\u0438\u043a\u0430\u00bb \u0434\u0435\u043f \u0430\u0442\u0430\u043b\u0430\u0442\u044b\u043d \u0436\u0430\u0493\u0434\u0430\u0439\u0493\u0430 \u0431\u0430\u0439\u043b\u0430\u043d\u044b\u0441\u0442\u044b. \u0416\u04af\u043a\u0442\u0456\u043b\u0456\u043a \u043a\u0435\u0437\u0456\u043d\u0434\u0435\u0433\u0456 \u043f\u0440\u0435\u043d\u0430\u0442\u0430\u043b\u044c\u0434\u044b \u0442\u0435\u0441\u0442\u0456\u043b\u0435\u0443\u0434\u0456 \u0456\u0437\u0434\u0435\u0443\u0433\u0435 \u0431\u043e\u043b\u0430\u0434\u044b <em>LMNA <\/em>\u04b1\u0440\u044b\u049b\u0442\u0430 HGPS \u0442\u0443\u0434\u044b\u0440\u0430\u0442\u044b\u043d \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u04e9\u0437\u0433\u0435\u0440\u0456\u0441.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0434\u0438\u0430\u0433\u043d\u043e\u0437\u044b \u049b\u0430\u043b\u0430\u0439 \u049b\u043e\u0439\u044b\u043b\u0430\u0434\u044b?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0434\u0438\u0430\u0433\u043d\u043e\u0437\u044b \u049b\u0430\u043b\u0430\u0439 \u049b\u043e\u0439\u044b\u043b\u0430\u0434\u044b?&quot; _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding=\u201d|50px||50px||true\u201d animation=toplion\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all=\u201d0px\u201d global_colors_info=\u201d{}\u201d sticky_enabled=\u201d0<\/p>\n<div id=\"1488059409784-71ca0fef-3046\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p>\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0433\u0435\u043d\u0456\u043d\u0456\u04a3 \u0442\u0430\u0440\u0438\u0445\u0438 \u0430\u0448\u044b\u043b\u0443\u044b\u043d\u0430 \u0431\u0430\u0439\u043b\u0430\u043d\u044b\u0441\u0442\u044b \u0431\u0456\u0437\u0434\u0435 \u0431\u0430\u0440 <strong>\u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0434\u044b \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430\u043b\u0430\u0443\u0434\u044b\u04a3 \u0442\u04af\u043f\u043a\u0456\u043b\u0456\u043a\u0442\u0456, \u0493\u044b\u043b\u044b\u043c\u0438 \u04d9\u0434\u0456\u0441\u0456<em>. <\/em><\/strong>\u0411\u04b1\u043b \u043e\u043b\u0430\u0440\u0434\u044b\u04a3 \u0434\u04b1\u0440\u044b\u0441 \u043a\u04af\u0442\u0456\u043c\u0434\u0456 \u0430\u043b\u0443\u044b \u04af\u0448\u0456\u043d \u0434\u04d9\u043b\u0456\u0440\u0435\u043a \u0436\u04d9\u043d\u0435 \u0435\u0440\u0442\u0435\u0440\u0435\u043a \u0434\u0438\u0430\u0433\u043d\u043e\u0437\u0434\u0430\u0440\u0493\u0430 \u04d9\u043a\u0435\u043b\u0435\u0434\u0456. Progeria \u0437\u0435\u0440\u0442\u0442\u0435\u0443 \u049b\u043e\u0440\u044b \u0431\u0430\u0440 <a href=\"https:\/\/www.progeriaresearch.org\/kk\/the-prf-diagnostic-testing-program\/\"><strong>\u0414\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u0442\u0435\u0441\u0442\u0456\u043b\u0435\u0443 \u0431\u0430\u0493\u0434\u0430\u0440\u043b\u0430\u043c\u0430\u0441\u044b <\/strong><\/a>\u0431\u04b1\u043b HGPS-\u043a\u0435 \u04d9\u043a\u0435\u043b\u0435\u0442\u0456\u043d Progeria \u0433\u0435\u043d\u0456\u043d\u0434\u0435\u0433\u0456 \u043d\u0430\u049b\u0442\u044b \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u04e9\u0437\u0433\u0435\u0440\u0456\u0441\u0442\u0456 \u043d\u0435\u043c\u0435\u0441\u0435 \u043c\u0443\u0442\u0430\u0446\u0438\u044f\u043d\u044b \u049b\u0430\u0440\u0430\u0441\u0442\u044b\u0440\u0430\u0434\u044b. \u0411\u0430\u0441\u0442\u0430\u043f\u049b\u044b \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0431\u0430\u0493\u0430\u043b\u0430\u0443\u0434\u0430\u043d \u043a\u0435\u0439\u0456\u043d (\u0431\u0430\u043b\u0430\u043d\u044b\u04a3 \u0441\u044b\u0440\u0442\u049b\u044b \u0442\u04af\u0440\u0456\u043d \u0436\u04d9\u043d\u0435 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430\u043b\u044b\u049b \u0436\u0430\u0437\u0431\u0430\u043b\u0430\u0440\u044b\u043d \u049b\u0430\u0440\u0430\u043f) \u0431\u0430\u043b\u0430\u043d\u044b\u04a3 \u049b\u0430\u043d\u044b\u043d\u044b\u04a3 \u04af\u043b\u0433\u0456\u0441\u0456 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0493\u0430 \u0442\u0435\u043a\u0441\u0435\u0440\u0456\u043b\u0435\u0434\u0456.  \u0413\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u0442\u0435\u0441\u0442\u0456\u043b\u0435\u0443 \u043a\u0435\u0439\u0431\u0456\u0440 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430 \u043c\u0435\u043a\u0435\u043c\u0435\u043b\u0435\u0440\u0456\u043d\u0434\u0435 \u0434\u0435 \u0431\u0430\u0440. \u04d8\u0440\u049b\u0430\u0448\u0430\u043d \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u043a\u0435\u04a3\u0435\u0441 \u0431\u0435\u0440\u0443 \u04b1\u0441\u044b\u043d\u044b\u043b\u0430\u0434\u044b.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u0435\u043c\u0456 \u0431\u0430\u0440 \u043c\u0430?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b\u04a3 \u0435\u043c\u0456 \u0431\u0430\u0440 \u043c\u0430?&quot; module_id=\u201d#ftn8\u2033 _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding||5px|\u201d0 animation_style=\u201dslide\u201d animation_direction=\u201dtop\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all_color=\u201dglobalcolors=\u201dpx sticky_enabled=\u201d0\u2033]<\/p>\n<div id=\"1488059409784-71ca0fef-3046\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p><em>\u0418\u04d9<\/em>! \u0422\u0430\u0440\u0438\u0445 \u0436\u0430\u0441\u0430\u043b\u0434\u044b <strong>2012 \u0436\u044b\u043b\u0434\u044b\u04a3 \u049b\u044b\u0440\u043a\u04af\u0439\u0435\u043a \u0430\u0439\u044b<\/strong>Progeria \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u044b\u043d\u044b\u04a3 \u0430\u043b\u0493\u0430\u0448\u049b\u044b \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0441\u044b\u043d\u0430\u0493\u044b\u043d\u044b\u04a3 \u043d\u04d9\u0442\u0438\u0436\u0435\u043b\u0435\u0440\u0456 \u0444\u0430\u0440\u043d\u0435\u0437\u0438\u043b\u0442\u0440\u0430\u043d\u0441\u0444\u0435\u0440\u0430\u0437\u0430 \u0442\u0435\u0436\u0435\u0433\u0456\u0448\u0456 (\u043d\u0435\u043c\u0435\u0441\u0435 FTI) \u043b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u0442\u0456\u04a3 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b \u0435\u043c\u0434\u0435\u0443\u0434\u0456\u04a3 \u0442\u0438\u0456\u043c\u0434\u0456 \u049b\u04b1\u0440\u0430\u043b\u044b \u0435\u043a\u0435\u043d\u0456\u043d \u043a\u04e9\u0440\u0441\u0435\u0442\u043a\u0435\u043d \u043a\u0435\u0437\u0434\u0435.<a href=\"#referencefour\" name=\"_ftnref1\">[5]<\/a>. \u0421\u044b\u043d\u0430\u049b\u0442\u044b\u04a3 \u0431\u0430\u0440\u043b\u044b\u049b \u049b\u0430\u0442\u044b\u0441\u0443\u0448\u044b\u043b\u0430\u0440\u044b \u0441\u0430\u043b\u043c\u0430\u049b\u0442\u044b\u04a3 \u04e9\u0441\u0443\u0456\u043d, \u0441\u04af\u0439\u0435\u043a \u049b\u04b1\u0440\u044b\u043b\u044b\u043c\u044b\u043d \u0436\u04d9\u043d\u0435 \u0435\u04a3 \u0431\u0430\u0441\u0442\u044b\u0441\u044b \u0436\u04af\u0440\u0435\u043a-\u0442\u0430\u043c\u044b\u0440 \u0436\u04af\u0439\u0435\u0441\u0456\u043d \u0436\u0430\u049b\u0441\u0430\u0440\u0442\u0443\u0434\u044b \u0431\u0430\u0441\u0442\u0430\u043d \u043a\u0435\u0448\u0456\u0440\u0434\u0456.<\/p>\n<p>\u041a\u0435\u0439\u0456\u043d\u0433\u0456 \u0435\u043a\u0456 \u0437\u0435\u0440\u0442\u0442\u0435\u0443, \u0431\u0456\u0440\u0435\u0443\u0456 <strong>2018<\/strong> \u0436\u044b\u043b\u044b \u0436\u0430\u0440\u0438\u044f\u043b\u0430\u043d\u0493\u0430\u043d <em>\u0410\u043c\u0435\u0440\u0438\u043a\u0430\u043d\u0434\u044b\u049b \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430 \u049b\u0430\u0443\u044b\u043c\u0434\u0430\u0441\u0442\u044b\u0493\u044b\u043d\u044b\u04a3 \u0436\u0443\u0440\u043d\u0430\u043b\u044b<\/em><em> (JAMA)<a href=\"#referencefour\" name=\"_ftnref2\">[6]<\/a>, <\/em>\u0436\u04d9\u043d\u0435 \u0431\u0456\u0440\u0435\u0443\u0456\u043d\u0435\u043d <strong>2023<\/strong> \u0436\u044b\u043b\u044b \u0436\u0430\u0440\u0438\u044f\u043b\u0430\u043d\u0493\u0430\u043d<em> \u0410\u0439\u043d\u0430\u043b\u044b\u043c<a href=\"#referencefour\" name=\"_ftnref1\">[7]<\/a>,<\/em> \u043b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0434\u0430 \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443\u0434\u0456 \u04b1\u0437\u0430\u0440\u0442\u0443\u0493\u0430 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435\u0442\u0456\u043d\u0456\u043d \u043a\u04e9\u0440\u0441\u0435\u0442\u0442\u0456.<\/p>\n<p>The <strong>2012<\/strong> \u0436\u04d9\u043d\u0435 <strong>2018<\/strong> \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u043b\u0435\u0440 \u0435\u0440\u0435\u043a\u0448\u0435 \u0436\u0430\u0493\u0434\u0430\u0439\u0493\u0430 \u04d9\u043a\u0435\u043b\u0434\u0456 <strong>2020<\/strong> \u0410\u049a\u0428-\u0442\u044b\u04a3 \u0410\u0437\u044b\u049b-\u0442\u04af\u043b\u0456\u043a \u0436\u04d9\u043d\u0435 \u0434\u04d9\u0440\u0456-\u0434\u04d9\u0440\u043c\u0435\u043a \u0431\u0430\u0441\u049b\u0430\u0440\u043c\u0430\u0441\u044b (FDA) \u049b\u0430\u0437\u0456\u0440 \u00ab\u0417\u043e\u043a\u0438\u043d\u0432\u0438\u00bb \u0434\u0435\u043f \u0430\u0442\u0430\u043b\u0430\u0442\u044b\u043d \u043b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u0442\u0456 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b \u0435\u043c\u0434\u0435\u0443\u0434\u0456\u04a3 \u0430\u043b\u0493\u0430\u0448\u049b\u044b \u049b\u04b1\u0440\u0430\u043b\u044b \u0440\u0435\u0442\u0456\u043d\u0434\u0435 \u043c\u0430\u049b\u04b1\u043b\u0434\u0430\u0434\u044b. PRF \u043c\u0438\u0441\u0441\u0438\u044f\u0441\u044b\u043d\u044b\u04a3 \u043c\u0430\u04a3\u044b\u0437\u0434\u044b \u043a\u0435\u0437\u0435\u04a3\u0456, \u0431\u04b1\u043b \u043c\u0430\u049b\u04b1\u043b\u0434\u0430\u0443 37 \u0435\u043b\u0434\u0435\u043d 96 \u0431\u0430\u043b\u0430\u043d\u044b \u0435\u043c\u0434\u0435\u0443 \u04af\u0448\u0456\u043d \u0411\u043e\u0441\u0442\u043e\u043d\u0493\u0430 \u04d9\u043a\u0435\u043b\u0433\u0435\u043d \u0442\u04e9\u0440\u0442 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0441\u044b\u043d\u0430\u049b\u0442\u044b \u049b\u0430\u043c\u0442\u0438\u0442\u044b\u043d 13 \u0436\u044b\u043b\u0434\u044b\u049b \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u043b\u0435\u0440\u0434\u0456\u04a3 \u0448\u044b\u04a3\u044b \u0431\u043e\u043b\u0434\u044b.<\/p>\n<p>\u041e\u0441\u044b \u043c\u0430\u04a3\u044b\u0437\u0434\u044b \u043a\u0435\u0437\u0435\u04a3\u043c\u0435\u043d Progeria FDA \u043c\u0430\u049b\u04b1\u043b\u0434\u0430\u0493\u0430\u043d \u0435\u043c\u0456 \u0431\u0430\u0440 \u0441\u0438\u0440\u0435\u043a \u043a\u0435\u0437\u0434\u0435\u0441\u0435\u0442\u0456\u043d \u0430\u0443\u0440\u0443\u043b\u0430\u0440\u0434\u044b\u04a3 5%-\u0434\u0435\u043d \u0430\u0437\u044b \u049b\u0430\u0442\u0430\u0440\u044b\u043d\u0430 \u049b\u043e\u0441\u044b\u043b\u0434\u044b.<\/p>\n<p>FDA \u043b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u0442\u0456 \u043c\u0430\u049b\u04b1\u043b\u0434\u0430\u0493\u0430\u043d\u043d\u0430\u043d \u043a\u0435\u0439\u0456\u043d \u043a\u04e9\u043f \u04b1\u0437\u0430\u043c\u0430\u0439 \u0415\u0443\u0440\u043e\u043f\u0430\u043b\u044b\u049b \u0434\u04d9\u0440\u0456-\u0434\u04d9\u0440\u043c\u0435\u043a \u0430\u0433\u0435\u043d\u0442\u0442\u0456\u0433\u0456 (EMA) \u043b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u0442\u0456 \u0415\u0443\u0440\u043e\u043f\u0430\u0434\u0430 2022 \u0436\u044b\u043b\u0434\u044b\u04a3 \u0448\u0456\u043b\u0434\u0435\u0441\u0456\u043d\u0434\u0435, \u0441\u043e\u0434\u0430\u043d \u043a\u0435\u0439\u0456\u043d \u0416\u0430\u043f\u043e\u043d\u0438\u044f\u043d\u044b\u04a3 \u0414\u0435\u043d\u0441\u0430\u0443\u043b\u044b\u049b \u0441\u0430\u049b\u0442\u0430\u0443, \u0435\u04a3\u0431\u0435\u043a \u0436\u04d9\u043d\u0435 \u04d9\u043b-\u0430\u0443\u049b\u0430\u0442 \u043c\u0438\u043d\u0438\u0441\u0442\u0440\u043b\u0456\u0433\u0456 (MHLW) 2024 \u0436\u044b\u043b\u0434\u044b\u04a3 \u049b\u0430\u04a3\u0442\u0430\u0440\u044b\u043d\u0434\u0430 \u049b\u043e\u043b\u0434\u0430\u043d\u0443\u0493\u0430 \u0440\u04b1\u049b\u0441\u0430\u0442 \u0431\u0435\u0440\u0434\u0456.<\/p>\n<p>\u041b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u0441\u0456\u0437 \u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u043e\u0440\u0442\u0430 \u0435\u0441\u0435\u043f\u043f\u0435\u043d 14,5 \u0436\u0430\u0441\u0442\u0430 \u0430\u0442\u0435\u0440\u043e\u0441\u043a\u043b\u0435\u0440\u043e\u0437\u0434\u0430\u043d (\u0436\u04af\u0440\u0435\u043a \u0436\u0435\u0442\u043a\u0456\u043b\u0456\u043a\u0441\u0456\u0437\u0434\u0456\u0433\u0456 \u043d\u0435\u043c\u0435\u0441\u0435 \u0438\u043d\u0441\u0443\u043b\u044c\u0442) \u04e9\u043b\u0435\u0434\u0456.<em> <a href=\"#referencefour\" name=\"_ftnref2\">[6]<\/a><\/em>\u00a0. \u04b0\u0437\u0430\u049b \u043c\u0435\u0440\u0437\u0456\u043c\u0434\u0456 \u043b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u043f\u0435\u043d \u0435\u043c\u0434\u0435\u0443 \u0436\u04af\u0440\u0435\u043a-\u049b\u0430\u043d \u0442\u0430\u043c\u044b\u0440\u043b\u0430\u0440\u044b \u0434\u0435\u043d\u0441\u0430\u0443\u043b\u044b\u0493\u044b \u0430\u0439\u0442\u0430\u0440\u043b\u044b\u049b\u0442\u0430\u0439 \u0436\u0430\u049b\u0441\u0430\u0440\u0430\u0434\u044b \u0436\u04d9\u043d\u0435 <strong>\u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443 \u04b1\u0437\u0430\u049b\u0442\u044b\u0493\u044b \u043e\u0440\u0442\u0430 \u0435\u0441\u0435\u043f\u043f\u0435\u043d 4,5 \u0436\u044b\u043b\u0493\u0430 \u04b1\u0437\u0430\u0440\u0493\u0430\u043d\u044b \u043a\u04e9\u0440\u0441\u0435\u0442\u0456\u043b\u0433\u0435\u043d<span>7<\/span>. \u00a0<\/strong>\u0411\u04b1\u043b 14,5 \u0436\u0430\u0441\u0442\u0430\u043d 20 \u0436\u0430\u0441\u049b\u0430 \u0434\u0435\u0439\u0456\u043d\u0433\u0456 \u043e\u0440\u0442\u0430\u0448\u0430 \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443 \u04b1\u0437\u0430\u049b\u0442\u044b\u0493\u044b\u043d 30% \u04b1\u043b\u0493\u0430\u0439\u0442\u0443!<\/p>\n<p>\u041b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431 \u0442\u0435\u0440\u0430\u043f\u0438\u044f\u0441\u044b\u043d\u044b\u04a3 \u0430\u0440\u049b\u0430\u0441\u044b\u043d\u0434\u0430 \u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u04b1\u0437\u0430\u0493\u044b\u0440\u0430\u049b \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0435\u0442\u0456\u043d\u0434\u0456\u043a\u0442\u0435\u043d, \u0434\u04d9\u0440\u0456\u0433\u0435\u0440\u043b\u0435\u0440 \u049b\u043e\u043b\u049b\u0430 \u0441\u0442\u0435\u043d\u043e\u0437\u044b\u043d (\u0436\u04af\u0440\u0435\u043a \u043a\u043b\u0430\u043f\u0430\u043d\u044b\u043d\u044b\u04a3 \u0442\u0430\u0440\u044b\u043b\u0443\u044b) \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043c\u0435\u043d \u0430\u0443\u044b\u0440\u0430\u0442\u044b\u043d \u0435\u0433\u0434\u0435 \u0436\u0430\u0441\u0442\u0430\u0493\u044b \u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u043c\u0435\u043d \u0436\u0430\u0441 \u0435\u0440\u0435\u0441\u0435\u043a\u0442\u0435\u0440\u0434\u0435\u0433\u0456 \u043f\u0440\u043e\u0431\u043b\u0435\u043c\u0430 \u0440\u0435\u0442\u0456\u043d\u0434\u0435 \u049b\u0430\u0440\u0430\u0441\u0442\u044b\u0440\u0430\u0434\u044b, \u0431\u04b1\u043b \u04e9\u043c\u0456\u0440\u0434\u0456 \u0441\u0430\u049b\u0442\u0430\u0439\u0442\u044b\u043d \u0445\u0438\u0440\u0443\u0440\u0433\u0438\u044f\u0493\u0430 \u049b\u043e\u043b\u0430\u0439\u043b\u044b \u0431\u043e\u043b\u0443\u044b \u043c\u04af\u043c\u043a\u0456\u043d. \u041a\u0435\u0439\u0431\u0456\u0440 \u0436\u0430\u0493\u0434\u0430\u0439\u043b\u0430\u0440\u0434\u0430 \u0436\u0430\u04a3\u0430 \u0436\u04af\u0440\u0435\u043a \u049b\u0430\u049b\u043f\u0430\u049b\u0448\u0430\u043b\u0430\u0440\u044b\u043d \u043d\u0435\u043c\u0435\u0441\u0435 \u0436\u04af\u0440\u0435\u043a\u0442\u0456 \u049b\u0430\u043c\u0442\u0430\u043c\u0430\u0441\u044b\u0437 \u0435\u0442\u0435\u0442\u0456\u043d \u0430\u0448\u044b\u049b \u049b\u0430\u043d \u0442\u0430\u043c\u044b\u0440\u043b\u0430\u0440\u044b\u043d (\u0441\u0442\u0435\u043d\u0442\u0442\u0435\u0440\u0434\u0456) \u0435\u043d\u0433\u0456\u0437\u0443 \u043e\u043f\u0435\u0440\u0430\u0446\u0438\u044f\u0441\u044b \u0430\u0443\u0440\u0443\u0434\u044b\u04a3 \u043a\u0435\u0439\u0456\u043d\u0433\u0456 \u043a\u0435\u0437\u0435\u04a3\u0434\u0435\u0440\u0456\u043d\u0434\u0435\u0433\u0456 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0442\u0435\u0440\u0434\u0456\u04a3 \u0434\u0435\u043d\u0441\u0430\u0443\u043b\u044b\u0493\u044b\u043d \u0436\u0430\u049b\u0441\u0430\u0440\u0442\u0443\u0493\u0430 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0442\u0456.<a href=\"#referencefour\" name=\"_ftnref1\"><span>[8]<\/span><\/a>.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;Progeria \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u043b\u0435\u0440\u0456\u043d\u0434\u0435\u0433\u0456 \u0441\u043e\u04a3\u0493\u044b \u0436\u0430\u04a3\u0430\u043b\u044b\u049b\u0442\u0430\u0440 \u049b\u0430\u043d\u0434\u0430\u0439?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u0434\u0435\u0433\u0456 \u0441\u043e\u04a3\u0493\u044b \u0436\u0430\u04a3\u0430\u043b\u044b\u049b\u0442\u0430\u0440 \u049b\u0430\u043d\u0434\u0430\u0439?&quot; module_id=\u201d#ftn8\u2033 _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding||5px|\u201d0 animation_style=\u201dslide\u201d animation_direction=\u201dtop\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all_color=\u201dglobalcolors=\u201dpx sticky_enabled=\u201d0\u2033]<\/p>\n<div id=\"1488059409784-71ca0fef-3046\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p>PRF \u0434\u0430\u043c\u0443\u044b\u043d\u0434\u0430 \u04af\u043b\u043a\u0435\u043d \u0440\u04e9\u043b \u0430\u0442\u049b\u0430\u0440\u0430\u0434\u044b <strong>\u04af\u0448 \u0431\u0430\u0441\u049b\u0430 \u0435\u043c\u0434\u0456\u043a \u0436\u043e\u043b<\/strong>, \u043e\u043b\u0430\u0440\u0434\u044b\u04a3 \u04d9\u0440\u049b\u0430\u0439\u0441\u044b\u0441\u044b Progeria \u0442\u0456\u043d\u0442\u0443\u0456\u0440\u0456\u043d\u0456\u04a3 \u04af\u043b\u0433\u0456\u043b\u0435\u0440\u0456\u043d\u0434\u0435 \u0437\u0435\u0440\u0442\u0442\u0435\u043b\u0433\u0435\u043d \u043a\u0435\u0437\u0434\u0435 \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443 \u04b1\u0437\u0430\u049b\u0442\u044b\u0493\u044b\u043d\u044b\u04a3 \u04d9\u0440\u0442\u04af\u0440\u043b\u0456 \u0434\u0435\u04a3\u0433\u0435\u0439\u043b\u0435\u0440\u0456\u043d \u043a\u04e9\u0440\u0441\u0435\u0442\u0442\u0456 \u2013 50%-\u0434\u0435\u043d \u0442\u0430\u04a3\u0493\u0430\u043b\u0430\u0440\u043b\u044b\u049b 140%! \u0411\u0456\u0437\u0434\u0456\u04a3 \u043c\u0430\u049b\u0441\u0430\u0442\u0442\u0430\u0440\u044b\u043c\u044b\u0437 - \u0436\u0430\u043b\u0493\u044b\u0437 \u043b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u0442\u0435\u043d \u0434\u0435 \u0436\u0430\u049b\u0441\u044b \u0436\u04b1\u043c\u044b\u0441 \u0456\u0441\u0442\u0435\u0439\u0442\u0456\u043d \u0436\u0430\u04a3\u0430 \u0435\u043c\u0434\u0435\u0443 \u04d9\u0434\u0456\u0441\u0442\u0435\u0440\u0456\u043d \u0442\u0430\u0431\u0443 \u0436\u04d9\u043d\u0435 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u043c\u0443\u0442\u0430\u0446\u0438\u044f\u043d\u044b \u0442\u04af\u0437\u0435\u0442\u0443 \u0430\u0440\u049b\u044b\u043b\u044b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b \u0435\u043c\u0434\u0435\u0443. <strong><em>\u0411\u0456\u0437 \u0430\u0443\u0440\u0443\u0434\u044b \u0430\u049b\u0443\u044b\u0437, \u0420\u041d\u049a \u0436\u04d9\u043d\u0435 \u0414\u041d\u049a \u0434\u0435\u04a3\u0433\u0435\u0439\u0456\u043d\u0434\u0435 \u043c\u0430\u049b\u0441\u0430\u0442 \u0435\u0442\u0456\u043f \u043e\u0442\u044b\u0440\u043c\u044b\u0437.<\/em><\/strong><\/p>\n<ol>\n<li><strong>\u0414\u041d\u049a \u043d\u0435\u0433\u0456\u0437\u0456\u043d \u04e9\u04a3\u0434\u0435\u0443<\/strong>: \u0411\u04b1\u043b \u0436\u043e\u043b \u0414\u041d\u049a \u0434\u0435\u04a3\u0433\u0435\u0439\u0456\u043d\u0434\u0435 Progeria \u0433\u0435\u043d\u0456\u043d\u0456\u04a3 \u043c\u0443\u0442\u0430\u0446\u0438\u044f\u0441\u044b\u043d \u0442\u04b1\u0440\u0430\u049b\u0442\u044b \u0442\u04af\u0440\u0434\u0435 \u0442\u04af\u0437\u0435\u0442\u0443\u0433\u0435 \u0431\u0430\u0493\u044b\u0442\u0442\u0430\u043b\u0493\u0430\u043d.<br \/>\u0436\u044b\u043b\u044b <strong>2021 \u0436\u044b\u043b\u0434\u044b\u04a3 \u049b\u0430\u04a3\u0442\u0430\u0440\u044b<\/strong>, \u0493\u044b\u043b\u044b\u043c\u0438 \u0436\u0443\u0440\u043d\u0430\u043b <em>\u0422\u0430\u0431\u0438\u0493\u0430\u0442<\/em> Progeria \u0442\u0456\u043d\u0442\u0443\u0456\u0440\u0456\u043d\u0456\u04a3 \u04af\u043b\u0433\u0456\u0441\u0456\u043d\u0434\u0435\u0433\u0456 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u0440\u0435\u0434\u0430\u043a\u0446\u0438\u044f\u043b\u0430\u0443 \u043a\u04e9\u043f\u0442\u0435\u0433\u0435\u043d \u0436\u0430\u0441\u0443\u0448\u0430\u043b\u0430\u0440\u0434\u0430\u0493\u044b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u043c\u0443\u0442\u0430\u0446\u0438\u044f\u0441\u044b\u043d \u0442\u04af\u0437\u0435\u0442\u0456\u043f, \u0431\u0456\u0440\u043d\u0435\u0448\u0435 \u043d\u0435\u0433\u0456\u0437\u0433\u0456 \u0430\u0443\u0440\u0443\u0434\u044b\u04a3 \u0431\u0435\u043b\u0433\u0456\u043b\u0435\u0440\u0456\u043d \u0436\u0430\u049b\u0441\u0430\u0440\u0442\u049b\u0430\u043d\u044b\u043d \u043a\u04e9\u0440\u0441\u0435\u0442\u0435\u0442\u0456\u043d \u0441\u0435\u0440\u043f\u0456\u043d\u0434\u0456 \u043d\u04d9\u0442\u0438\u0436\u0435\u043b\u0435\u0440\u0434\u0456 \u0436\u0430\u0440\u0438\u044f\u043b\u0430\u0434\u044b. <strong>\u0442\u044b\u0448\u049b\u0430\u043d\u0434\u0430\u0440\u0434\u044b\u04a3 \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443 \u04b1\u0437\u0430\u049b\u0442\u044b\u0493\u044b\u043d 140% \u04b1\u0437\u0430\u0440\u0442\u0442\u044b<\/strong><a href=\"#referencefour\" name=\"_ftnref1\">[9].<\/a> \u0411\u04b1\u043b \u043d\u04d9\u0442\u0438\u0436\u0435\u043b\u0435\u0440\u0434\u0456 \u0437\u0435\u0440\u0442\u0442\u0435\u0443 \u04af\u0448\u0456\u043d \u049b\u043e\u0441\u044b\u043c\u0448\u0430 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u0493\u0430 \u0434\u0435\u0439\u0456\u043d\u0433\u0456 \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u043b\u0435\u0440 \u049b\u0430\u0436\u0435\u0442, \u043e\u043b\u0430\u0440 \u0431\u0456\u0440 \u043a\u04af\u043d\u0456 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0441\u044b\u043d\u0430\u049b\u049b\u0430 \u04d9\u043a\u0435\u043b\u0435\u0434\u0456 \u0434\u0435\u043f \u04af\u043c\u0456\u0442\u0442\u0435\u043d\u0435\u043c\u0456\u0437.<\/li>\n<\/ol>\n<p style=\"padding-left: 120px;\"><em>\u00ab\u0411\u0456\u0437\u0434\u0456\u04a3 Progeria \u0442\u0456\u043d\u0442\u0443\u0456\u0440\u0456\u043d\u0456\u04a3 \u04af\u043b\u0433\u0456\u0441\u0456\u043d\u0434\u0435\u0433\u0456 \u0431\u04b1\u043b \u04d9\u0441\u0435\u0440\u043b\u0456 \u0440\u0435\u0430\u043a\u0446\u0438\u044f\u043d\u044b \u043a\u04e9\u0440\u0443 - \u043c\u0435\u043d \u0434\u04d9\u0440\u0456\u0433\u0435\u0440-\u0493\u0430\u043b\u044b\u043c \u0440\u0435\u0442\u0456\u043d\u0434\u0435 40 \u0436\u044b\u043b \u0456\u0448\u0456\u043d\u0434\u0435 \u049b\u0430\u0442\u044b\u0441\u049b\u0430\u043d \u0435\u04a3 \u049b\u044b\u0437\u044b\u049b\u0442\u044b \u0442\u0435\u0440\u0430\u043f\u0438\u044f\u043b\u044b\u049b \u043e\u049b\u0438\u0493\u0430\u043b\u0430\u0440\u0434\u044b\u04a3 \u0431\u0456\u0440\u0456\u00bb, - \u0434\u0435\u0434\u0456 \u0424\u0440\u044d\u043d\u0441\u0438\u0441 \u041a\u043e\u043b\u043b\u0438\u043d\u0437, MD, PhD.<\/em><\/p>\n<ol start=\"2\">\n<li><strong>\u0420\u041d\u049a \u0442\u0435\u0440\u0430\u043f\u0438\u044f\u0441\u044b<\/strong>: \u0411\u04b1\u043b \u0436\u043e\u043b \u0420\u041d\u049a \u0434\u0435\u04a3\u0433\u0435\u0439\u0456\u043d\u0434\u0435\u0433\u0456 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u043c\u0443\u0442\u0430\u0446\u0438\u044f\u043d\u044b \u0442\u04af\u0437\u0435\u0442\u0443 \u0430\u0440\u049b\u044b\u043b\u044b \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u04e9\u043d\u0434\u0456\u0440\u0456\u0441\u0456\u043d \u0442\u043e\u049b\u0442\u0430\u0442\u0443\u0493\u0430 \u0431\u0430\u0493\u044b\u0442\u0442\u0430\u043b\u0493\u0430\u043d.<br \/>\u0436\u044b\u043b\u044b <strong>2021 \u0436\u044b\u043b\u0434\u044b\u04a3 \u043d\u0430\u0443\u0440\u044b\u0437\u044b<\/strong>, PRF \u0420\u041d\u049a-\u0442\u0435\u0440\u0430\u043f\u0435\u0432\u0442\u0438\u043a\u0430\u0441\u044b\u043d \u049b\u043e\u043b\u0434\u0430\u043d\u0443 \u0431\u043e\u0439\u044b\u043d\u0448\u0430 \u0435\u043a\u0456 \u04e9\u0442\u0435 \u049b\u044b\u0437\u044b\u049b\u0442\u044b \u0441\u0435\u0440\u043f\u0456\u043d\u0434\u0456 \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u043b\u0435\u0440\u0433\u0435 \u04af\u043b\u0435\u0441 \u049b\u043e\u0441\u0442\u044b, \u043e\u043b\u0430\u0440\u0434\u044b\u04a3 \u0435\u043a\u0435\u0443\u0456 \u0434\u0435 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u043d\u0456\u04a3 \u0420\u041d\u049a \u0434\u0435\u04a3\u0433\u0435\u0439\u0456\u043d\u0434\u0435 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u04e9\u043d\u0434\u0456\u0440\u0443\u0433\u0435 \u049b\u0430\u0431\u0456\u043b\u0435\u0442\u0456\u043d \u0431\u043b\u043e\u043a\u0442\u0430\u0443\u0493\u0430 \u0442\u044b\u0440\u044b\u0441\u0430\u0434\u044b. \u0411\u0456\u0440 \u0437\u0435\u0440\u0442\u0442\u0435\u0443 Progeria \u0442\u044b\u0448\u049b\u0430\u043d\u0434\u0430\u0440\u044b\u043d SRP2001 \u0434\u0435\u043f \u0430\u0442\u0430\u043b\u0430\u0442\u044b\u043d \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u043f\u0435\u043d \u0435\u043c\u0434\u0435\u0443 \u0437\u0438\u044f\u043d\u0434\u044b \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u043c\u0420\u041d\u049a-\u043d\u044b \u0436\u04d9\u043d\u0435 \u0434\u0435\u043d\u0435\u043d\u0456\u04a3 \u043d\u0435\u0433\u0456\u0437\u0433\u0456 \u0430\u0440\u0442\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u043e\u043b\u044b\u043f \u0442\u0430\u0431\u044b\u043b\u0430\u0442\u044b\u043d \u0430\u043e\u0440\u0442\u0430\u0434\u0430, \u0441\u043e\u043d\u0434\u0430\u0439-\u0430\u049b \u0431\u0430\u0441\u049b\u0430 \u0442\u0456\u043d\u0434\u0435\u0440\u0434\u0435\u0433\u0456 \u0430\u049b\u0443\u044b\u0437 \u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u044f\u0441\u044b\u043d \u0442\u04e9\u043c\u0435\u043d\u0434\u0435\u0442\u0435\u0442\u0456\u043d\u0456\u043d \u043a\u04e9\u0440\u0441\u0435\u0442\u0442\u0456. \u0417\u0435\u0440\u0442\u0442\u0435\u0443\u0434\u0456\u04a3 \u0441\u043e\u04a3\u044b\u043d\u0434\u0430 \u0442\u044b\u0448\u049b\u0430\u043d\u0434\u0430\u0440 \u043a\u04e9\u0440\u0441\u0435\u0442\u0442\u0456 <strong>62% \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443\u0456\u043d \u0430\u0440\u0442\u0442\u044b\u0440\u0434\u044b<\/strong><a href=\"#referencefour\" name=\"_ftnref1\">[10]<\/a><strong><strong>.<br \/><\/strong><\/strong>\u0411\u0430\u0441\u049b\u0430 \u0437\u0435\u0440\u0442\u0442\u0435\u0443 LB143 \u0434\u0435\u043f \u0430\u0442\u0430\u043b\u0430\u0442\u044b\u043d \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u043f\u0435\u043d \u0435\u043c\u0434\u0435\u0443\u0434\u0435\u043d \u043a\u0435\u0439\u0456\u043d \u04d9\u0440\u0442\u04af\u0440\u043b\u0456 \u0442\u0456\u043d\u0434\u0435\u0440\u0434\u0435\u0433\u0456 \u0443\u044b\u0442\u0442\u044b \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u04e9\u043d\u0434\u0456\u0440\u0435\u0442\u0456\u043d \u0420\u041d\u049a-\u043d\u044b\u04a3 90 \u2013 95% \u0442\u04e9\u043c\u0435\u043d\u0434\u0435\u0443\u0456\u043d \u043a\u04e9\u0440\u0441\u0435\u0442\u0442\u0456. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u043f\u0440\u043e\u0442\u0435\u0438\u043d\u0456\u043d\u0456\u04a3 \u0442\u04e9\u043c\u0435\u043d\u0434\u0435\u0443\u0456 \u0436\u04af\u0440\u0435\u043a \u043f\u0435\u043d \u0430\u043e\u0440\u0442\u0430\u043d\u044b\u04a3 \u049b\u043e\u0441\u044b\u043c\u0448\u0430 \u0436\u0430\u049b\u0441\u0430\u0440\u0443\u044b\u043c\u0435\u043d \u0431\u0430\u0443\u044b\u0440\u0434\u0430 \u0435\u04a3 \u0442\u0438\u0456\u043c\u0434\u0456 \u0431\u043e\u043b\u0434\u044b.<a href=\"#referencefour\" name=\"_ftnref1\"><span>[11]<\/span><\/a>\u0411\u04b1\u043b \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430\u043b\u044b\u049b \u0442\u04af\u0437\u0435\u0442\u0443 \u0443\u0430\u049b\u044b\u0442\u0448\u0430 \u0431\u043e\u043b\u044b\u043f \u0442\u0430\u0431\u044b\u043b\u0430\u0434\u044b, \u0441\u043e\u043d\u0434\u044b\u049b\u0442\u0430\u043d \u0442\u04af\u0437\u0435\u0442\u0443\u0434\u0456 \u0441\u0430\u049b\u0442\u0430\u0443 \u04af\u0448\u0456\u043d \u04af\u0437\u0434\u0456\u043a\u0441\u0456\u0437 \u0435\u043c\u0434\u0435\u0443 \u049b\u0430\u0436\u0435\u0442.<\/li>\n<li><strong>\u041a\u0456\u0448\u0456 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u0430 (\u0434\u04d9\u0440\u0456\u043b\u0435\u0440)<\/strong>: \u0411\u04b1\u043b \u0436\u043e\u043b \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b \u0442\u0443\u0434\u044b\u0440\u0430\u0442\u044b\u043d \u0443\u043b\u044b \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u0430\u049b\u0443\u044b\u0437\u044b\u043d\u044b\u04a3 \u0434\u0435\u04a3\u0433\u0435\u0439\u0456\u043d \u0442\u04e9\u043c\u0435\u043d\u0434\u0435\u0442\u0443\u0433\u0435 \u0431\u0430\u0493\u044b\u0442\u0442\u0430\u043b\u0493\u0430\u043d.<br \/>\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u043d\u0438\u043d \u0434\u0435\u043f \u0430\u0442\u0430\u043b\u0430\u0442\u044b\u043d \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442 \u04af\u043b\u043a\u0435\u043d \u04af\u043c\u0456\u0442 \u043a\u04e9\u0440\u0441\u0435\u0442\u0442\u0456. Progeria \u0442\u0456\u043d\u0442\u0443\u0456\u0440\u0456\u043d\u0456\u04a3 \u04af\u043b\u0433\u0456\u0441\u0456\u043d\u0434\u0435 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d\u0438\u043d \u0434\u0435\u043d\u0435 \u0441\u0430\u043b\u043c\u0430\u0493\u044b\u043d \u04b1\u043b\u0493\u0430\u0439\u0442\u0442\u044b \u0436\u04d9\u043d\u0435 \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443 \u04b1\u0437\u0430\u049b\u0442\u044b\u0493\u044b\u043d 10 \u0430\u043f\u0442\u0430\u0493\u0430 \u04b1\u0437\u0430\u0440\u0442\u0442\u044b, \u0431\u04b1\u043b \u043b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u043f\u0435\u043d \u0435\u043c\u0434\u0435\u043b\u0433\u0435\u043d \u0442\u044b\u0448\u049b\u0430\u043d\u0434\u0430\u0440\u0434\u044b\u04a3 \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443 \u04b1\u0437\u0430\u049b\u0442\u044b\u0493\u044b\u043d \u0435\u043a\u0456 \u0430\u043f\u0442\u0430\u0493\u0430 \u04b1\u0437\u0430\u0440\u0442\u0443\u043c\u0435\u043d \u0441\u0430\u043b\u044b\u0441\u0442\u044b\u0440\u0493\u0430\u043d\u0434\u0430 \u0430\u0439\u0442\u0430\u0440\u043b\u044b\u049b\u0442\u0430\u0439 \u0436\u0435\u0442\u0456\u0441\u0442\u0456\u043a.<a href=\"#referencefour\" name=\"_ftnref1\">[12]<\/a>Progeria \u0437\u0435\u0440\u0442\u0442\u0435\u0443 \u0441\u0430\u043b\u0430\u0441\u044b \u0430\u0439\u0442\u0430\u0440\u043b\u044b\u049b\u0442\u0430\u0439 \u0436\u0435\u0442\u0456\u0441\u0442\u0456\u043a\u0442\u0435\u0440\u0433\u0435 \u049b\u043e\u043b \u0436\u0435\u0442\u043a\u0456\u0437\u0443\u0434\u0435, \u0442\u0438\u0456\u043c\u0434\u0456 \u0435\u043c\u0434\u0435\u0443 \u04d9\u0434\u0456\u0441\u0442\u0435\u0440\u0456\u043d \u0456\u0437\u0434\u0435\u0443 \u0436\u04d9\u043d\u0435 \u0435\u043c\u0434\u0435\u0443 \u0436\u0430\u043b\u0493\u0430\u0441\u0443\u0434\u0430, \u0430\u0443\u049b\u044b\u043c\u044b \u043c\u0435\u043d \u043a\u04af\u0440\u0434\u0435\u043b\u0456\u043b\u0456\u0433\u0456 \u04af\u0437\u0434\u0456\u043a\u0441\u0456\u0437 \u04e9\u0441\u0456\u043f \u043a\u0435\u043b\u0435\u0434\u0456. \u041a\u0435\u0440\u0435\u043c\u0435\u0442, \u044b\u043d\u0442\u0430\u043b\u044b \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u0448\u0456\u043b\u0435\u0440 \u0431\u04b1\u043b \u0441\u0430\u043b\u0430\u043d\u044b \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0493\u0430 \u04b1\u0437\u0430\u049b, \u0441\u0430\u043b\u0430\u0443\u0430\u0442\u0442\u044b \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443\u0433\u0435 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435\u0442\u0456\u043d, \u0441\u043e\u043d\u044b\u043c\u0435\u043d \u049b\u0430\u0442\u0430\u0440 \u0436\u04af\u0440\u0435\u043a \u0430\u0443\u0440\u0443\u044b \u043c\u0435\u043d \u049b\u0430\u0440\u0442\u0430\u044e\u0434\u044b \u0430\u0448\u0443\u0493\u0430 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435\u0442\u0456\u043d \u0436\u0435\u0442\u0456\u0441\u0442\u0456\u043a\u0442\u0435\u0440 \u043c\u0435\u043d \u0436\u0430\u04a3\u0430 \u0435\u043c\u0434\u0435\u0443 \u04d9\u0434\u0456\u0441\u0442\u0435\u0440\u0456\u043d\u0435 \u0430\u043b\u044b\u043f \u0431\u0430\u0440\u0430\u0434\u044b. \u0415\u043c\u0434\u0435\u0443 \u043c\u0435\u043d \u0435\u043c\u0434\u0435\u0443\u0434\u0456\u04a3 \u0436\u0430\u04a3\u0430 \u0436\u043e\u043b\u0434\u0430\u0440\u044b\u043d \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u0434\u0435\u043d \u0431\u0430\u0441\u049b\u0430, 2023 \u0436\u044b\u043b\u0434\u044b\u04a3 \u043d\u0430\u0443\u0440\u044b\u0437 \u0430\u0439\u044b\u043d\u0434\u0430 , PRF \u0430\u0448\u044b\u043b\u0443\u044b \u0442\u0443\u0440\u0430\u043b\u044b \u049b\u043e\u0440\u044b\u0442\u044b\u043d\u0434\u044b\u043b\u0430\u0440\u0434\u044b \u0445\u0430\u0431\u0430\u0440\u043b\u0430\u0434\u044b <strong>Progeria \u0431\u0438\u043e\u043c\u0430\u0440\u043a\u0435\u0440\u0456, \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d\u0434\u0456 \u04e9\u043b\u0448\u0435\u0443\u0434\u0456\u04a3 \u0436\u0430\u04a3\u0430 \u04d9\u0434\u0456\u0441\u0456<\/strong>, \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b \u0442\u0443\u0434\u044b\u0440\u0430\u0442\u044b\u043d \u0443\u043b\u044b \u0430\u049b\u0443\u044b\u0437. \u0411\u0438\u043e\u043c\u0430\u0440\u043a\u0435\u0440 \u0435\u0441\u0456\u0440\u0442\u043a\u0456\u043d\u0456\u04a3 \u0430\u049b\u044b\u043b\u0434\u044b \u0436\u04d9\u043d\u0435 \u0436\u044b\u043b\u0434\u0430\u043c\u044b\u0440\u0430\u049b \u0441\u044b\u043d\u0430\u049b\u0442\u0430\u0440\u044b\u043d \u0436\u04d9\u043d\u0435 \u0436\u0430\u049b\u0441\u044b\u0440\u0430\u049b \u0435\u043c\u0434\u0435\u0443\u0434\u0456 \u0443\u04d9\u0434\u0435 \u0435\u0442\u0435\u0442\u0456\u043d \u043e\u0439\u044b\u043d \u04e9\u0437\u0433\u0435\u0440\u0442\u0435\u0442\u0456\u043d \u049b\u0430\u0431\u0456\u043b\u0435\u0442\u0456\u043d\u0435 \u0438\u0435. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u043d \u0434\u0435\u04a3\u0433\u0435\u0439\u0456\u043d 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\u0431\u0443\u044b\u043d\u0434\u0430\u0440\u0434\u044b\u04a3 \u043a\u043e\u043d\u0442\u0440\u0430\u043a\u0442\u0443\u0440\u0430\u0441\u044b \u0436\u04d9\u043d\u0435 \u0444\u0443\u043d\u043a\u0446\u0438\u044f\u0441\u044b \u0441\u0438\u044f\u049b\u0442\u044b \u0431\u0430\u0441\u049b\u0430 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0441\u044b\u043d\u0430\u049b\u0442\u0430\u0440\u0493\u0430 \u0436\u0435\u0442\u0435\u043a\u0448\u0456 \u0440\u0435\u0442\u0456\u043d\u0434\u0435 \u0442\u0435\u043a\u0441\u0435\u0440\u0456\u043b\u0435\u0442\u0456\u043d \u0435\u043c\u0434\u0435\u0440\u0434\u0456\u04a3 \u0442\u0438\u0456\u043c\u0434\u0456\u043b\u0456\u0433\u0456 \u0442\u0443\u0440\u0430\u043b\u044b \u0435\u0440\u0442\u0435\u0440\u0435\u043a \u0430\u049b\u043f\u0430\u0440\u0430\u0442 \u0431\u0435\u0440\u0443; \u0442.\u0431., \u043e\u043b\u0430\u0440\u0434\u044b\u04a3 \u0431\u0430\u0440\u043b\u044b\u0493\u044b\u043d \u043a\u04e9\u0440\u0441\u0435\u0442\u0443 \u04af\u0448\u0456\u043d \u04d9\u043b\u0434\u0435\u049b\u0430\u0439\u0434\u0430 \u043a\u04e9\u043f \u0443\u0430\u049b\u044b\u0442 \u049b\u0430\u0436\u0435\u0442. \u0411\u0456\u0437 \u0435\u043d\u0434\u0456 \u0435\u043c\u0434\u0435\u0443\u0434\u0456\u04a3 \u0430\u0440\u0442\u044b\u049b\u0448\u044b\u043b\u044b\u049b\u0442\u0430\u0440\u044b\u043d \u0435\u043c\u0434\u0435\u0443\u0434\u0456 \u0431\u0430\u0441\u0442\u0430\u0493\u0430\u043d\u043d\u0430\u043d \u043a\u0435\u0439\u0456\u043d \u0442\u04e9\u0440\u0442 \u0430\u0439\u0434\u044b\u04a3 \u0456\u0448\u0456\u043d\u0434\u0435 \u0442\u04af\u0441\u0456\u043d\u0435 \u0430\u043b\u0430\u043c\u044b\u0437 \u043d\u0435\u043c\u0435\u0441\u0435 \u049b\u0430\u0436\u0435\u0442\u0441\u0456\u0437 \u0436\u0430\u043d\u0430\u043c\u0430 \u04d9\u0441\u0435\u0440\u043b\u0435\u0440\u0434\u0456 \u0431\u043e\u043b\u0434\u044b\u0440\u043c\u0430\u0443 \u04af\u0448\u0456\u043d \u0441\u044b\u043d\u0430\u049b\u049b\u0430 \u049b\u0430\u0442\u044b\u0441\u0443\u0448\u044b\u0493\u0430 \u043f\u0430\u0439\u0434\u0430\u0441\u044b \u0436\u043e\u049b \u0435\u043c\u0434\u0435\u0443\u0434\u0456 \u0442\u043e\u049b\u0442\u0430\u0442\u0430 \u0430\u043b\u0430\u043c\u044b\u0437.<a href=\"#referencefour\" name=\"_ftnref1\">[13]<\/a><a href=\"#_ftnref1\" name=\"_ftn1\"><span><\/span><\/a> <a href=\"#_ftnref8\" name=\"_ftn1\"><\/a><\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;PRF \u0431\u043e\u043b\u0430\u0448\u0430\u049b \u0435\u043c\u0434\u0435\u0443\u0433\u0435 \u0431\u0430\u0493\u044b\u0442\u0442\u0430\u043b\u0493\u0430\u043d \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u043b\u0435\u0440\u0434\u0456 \u049b\u0430\u043b\u0430\u0439 \u0430\u043b\u0493\u0430 \u0436\u044b\u043b\u0436\u044b\u0442\u0443\u0434\u0430 \u0436\u04d9\u043d\u0435 \u0431\u04af\u0433\u0456\u043d\u0434\u0435 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043c\u0435\u043d \u0430\u0443\u044b\u0440\u0430\u0442\u044b\u043d \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0493\u0430 \u049b\u0430\u043b\u0430\u0439 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0443\u0434\u0435?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;PRF \u0431\u043e\u043b\u0430\u0448\u0430\u049b \u0435\u043c\u0434\u0435\u0443\u0433\u0435 \u0431\u0430\u0493\u044b\u0442\u0442\u0430\u043b\u0493\u0430\u043d \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u043b\u0435\u0440\u0434\u0456 \u049b\u0430\u043b\u0430\u0439 \u0430\u043b\u0493\u0430 \u0436\u044b\u043b\u0436\u044b\u0442\u0443\u0434\u0430 \u0436\u04d9\u043d\u0435 \u0431\u04af\u0433\u0456\u043d\u0434\u0435 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043c\u0435\u043d \u0430\u0443\u044b\u0440\u0430\u0442\u044b\u043d \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0493\u0430 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0443\u0434\u0435?&quot; _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding=\u201d|50px||50px||true\u201d animation=toplion\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all=\u201d0px\u201d global_colors_info=\u201d{}\u201d sticky_enabled=\u201d0<\/p>\n<div id=\"1488059409784-71ca0fef-3046\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<div class=\"vc_tta-panel-heading\">\n<p align=\"left\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-4731\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/HBenglish-front.jpg\" sizes=\"(max-width: 200px) 100vw, 200px\" srcset=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/HBenglish-front.jpg 200w, https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/HBenglish-front-78x100.jpg 78w\" alt=\"\" width=\"200\" height=\"257\" \/>Progeria \u0437\u0435\u0440\u0442\u0442\u0435\u0443 \u049b\u043e\u0440\u044b <strong>\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430\u043b\u044b\u049b \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u043b\u0435\u0440\u0434\u0456 \u049b\u0430\u0440\u0436\u044b\u043b\u0430\u043d\u0434\u044b\u0440\u0430\u0434\u044b <\/strong>\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043d\u044b \u0435\u043c\u0434\u0435\u0443\u0433\u0435 \u0436\u04d9\u043d\u0435 \u0435\u043c\u0434\u0435\u0443\u0433\u0435 \u0431\u0430\u0493\u044b\u0442\u0442\u0430\u043b\u0493\u0430\u043d. PRF-\u043d\u0456\u04a3 \u0434\u0435 \u04e9\u0437\u0456\u043d\u0434\u0456\u043a \u0435\u0440\u0435\u043a\u0448\u0435\u043b\u0456\u0433\u0456 \u0431\u0430\u0440 <a href=\"https:\/\/www.progeriaresearch.org\/kk\/cell-and-tissue-bank\/\"><strong>\u0416\u0430\u0441\u0443\u0448\u0430 \u0436\u04d9\u043d\u0435 \u04b1\u043b\u043f\u0430 \u0431\u0430\u043d\u043a\u0456<\/strong><\/a><strong>\u00a0<\/strong>\u0411\u04b1\u043b \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u0448\u0456\u043b\u0435\u0440\u0433\u0435 \u04e9\u0437 \u0442\u04d9\u0436\u0456\u0440\u0438\u0431\u0435\u043b\u0435\u0440\u0456\u043d \u0436\u04af\u0440\u0433\u0456\u0437\u0443\u0433\u0435 \u049b\u0430\u0436\u0435\u0442\u0442\u0456 \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u044f\u043b\u044b\u049b \u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u0434\u0430\u0440\u0434\u044b \u049b\u0430\u043c\u0442\u0430\u043c\u0430\u0441\u044b\u0437 \u0435\u0442\u0435\u0434\u0456. \u0421\u043e\u043d\u044b\u043c\u0435\u043d \u049b\u0430\u0442\u0430\u0440, PRF \u0431\u0430\u0440 <a href=\"https:\/\/www.progeriaresearch.org\/kk\/medical-database\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>\u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0430\u043b\u044b\u049b \u0436\u04d9\u043d\u0435 \u0493\u044b\u043b\u044b\u043c\u0438 \u0434\u0435\u0440\u0435\u043a\u0442\u0435\u0440 \u0431\u0430\u0437\u0430\u0441\u044b<\/strong><\/a><strong>\u00a0\u2013 <\/strong>\u0431\u04af\u043a\u0456\u043b \u04d9\u043b\u0435\u043c \u0431\u043e\u0439\u044b\u043d\u0448\u0430 Progeria \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0442\u0435\u0440\u0456\u043d\u0435\u043d \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430\u043b\u044b\u049b \u0430\u049b\u043f\u0430\u0440\u0430\u0442\u0442\u044b\u04a3 \u043e\u0440\u0442\u0430\u043b\u044b\u049b\u0442\u0430\u043d\u0434\u044b\u0440\u044b\u043b\u0493\u0430\u043d \u0436\u0438\u043d\u0430\u0493\u044b. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0442\u0443\u0440\u0430\u043b\u044b \u043a\u04e9\u0431\u0456\u0440\u0435\u043a \u0442\u04af\u0441\u0456\u043d\u0443\u0433\u0435 \u0436\u04d9\u043d\u0435 \u0435\u043c\u0434\u0435\u0443 \u04b1\u0441\u044b\u043d\u044b\u0441\u0442\u0430\u0440\u044b\u043d \u04d9\u0437\u0456\u0440\u043b\u0435\u0443\u0433\u0435 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0443 \u04af\u0448\u0456\u043d \u0434\u0435\u0440\u0435\u043a\u0442\u0435\u0440 \u043c\u04b1\u049b\u0438\u044f\u0442 \u0442\u0430\u043b\u0434\u0430\u043d\u0430\u0434\u044b.<\/p>\n<p>Progeria \u0431\u0430\u0440 \u0430\u0434\u0430\u043c\u0493\u0430 \u043a\u04af\u0442\u0456\u043c \u0436\u0430\u0441\u0430\u0443 \u0442\u0443\u0440\u0430\u043b\u044b \u043a\u04e9\u043f\u0442\u0435\u0433\u0435\u043d \u0441\u04b1\u0440\u0430\u049b\u0442\u0430\u0440\u0493\u0430 \u0436\u0430\u0443\u0430\u043f \u0431\u0435\u0440\u0443 \u04af\u0448\u0456\u043d PRF \u0436\u0430\u0440\u0438\u044f\u043b\u0430\u0434\u044b <a href=\"https:\/\/www.progeriaresearch.org\/kk\/patient-care-and-handbook\/\"><strong>Progeria \u0430\u043d\u044b\u049b\u0442\u0430\u043c\u0430\u043b\u044b\u0493\u044b<\/strong><\/a><strong>\u00a0<\/strong>\u043e\u0442\u0431\u0430\u0441\u044b\u043b\u0430\u0440 \u043c\u0435\u043d \u0434\u04d9\u0440\u0456\u0433\u0435\u0440\u043b\u0435\u0440\u0433\u0435 \u0430\u0440\u043d\u0430\u043b\u0493\u0430\u043d. \u041d\u04b1\u0441\u049b\u0430\u0443\u043b\u044b\u049b \u043d\u0435\u0433\u0456\u0437\u0433\u0456 \u0434\u0435\u043d\u0441\u0430\u0443\u043b\u044b\u049b \u0444\u0430\u043a\u0442\u0456\u043b\u0435\u0440\u0456\u043d\u0435\u043d \u0431\u0430\u0441\u0442\u0430\u043f \u043a\u04af\u043d\u0434\u0435\u043b\u0456\u043a\u0442\u0456 \u043a\u04af\u0442\u0456\u043c \u0431\u043e\u0439\u044b\u043d\u0448\u0430 \u04b1\u0441\u044b\u043d\u044b\u0441\u0442\u0430\u0440\u0493\u0430, \u043a\u0435\u04a3 \u0430\u0443\u049b\u044b\u043c\u0434\u044b \u0435\u043c\u0434\u0435\u0443 \u043d\u04b1\u0441\u049b\u0430\u0443\u043b\u0430\u0440\u044b\u043d\u0430 \u0434\u0435\u0439\u0456\u043d \u0431\u04af\u043a\u0456\u043b \u04d9\u043b\u0435\u043c \u0431\u043e\u0439\u044b\u043d\u0448\u0430 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0430\u0434\u0430\u043c\u0434\u0430\u0440 \u04af\u0448\u0456\u043d \u04e9\u043c\u0456\u0440 \u0441\u0430\u043f\u0430\u0441\u044b\u043d \u043e\u04a3\u0442\u0430\u0439\u043b\u0430\u043d\u0434\u044b\u0440\u0443\u0493\u0430 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435\u0442\u0456\u043d \u049b\u043e\u043b\u0434\u0430\u0443\u0448\u044b \u0440\u0435\u0441\u0443\u0440\u0441\u0442\u044b \u04b1\u0441\u044b\u043d\u0430\u0434\u044b. \u0410\u043d\u044b\u049b\u0442\u0430\u043c\u0430\u043b\u044b\u049b\u0442\u044b\u04a3 \u0435\u04a3 \u0441\u043e\u04a3\u0493\u044b \u0431\u0430\u0441\u044b\u043b\u044b\u043c\u044b \u0430\u0493\u044b\u043b\u0448\u044b\u043d, \u0438\u0441\u043f\u0430\u043d, \u0436\u0430\u043f\u043e\u043d, \u043f\u043e\u0440\u0442\u0443\u0433\u0430\u043b, \u0438\u0442\u0430\u043b\u044c\u044f\u043d, \u0430\u0440\u0430\u0431 \u0436\u04d9\u043d\u0435 \u049b\u044b\u0442\u0430\u0439 \u0442\u0456\u043b\u0434\u0435\u0440\u0456\u043d\u0434\u0435 \u049b\u043e\u043b \u0436\u0435\u0442\u0456\u043c\u0434\u0456. \u0410\u043d\u044b\u049b\u0442\u0430\u043c\u0430 \u0431\u0430\u0441\u049b\u0430 \u0442\u0456\u043b\u0434\u0435\u0440\u0434\u0435 \u0434\u0435 \u049b\u043e\u043b\u0436\u0435\u0442\u0456\u043c\u0434\u0456 \u0431\u043e\u043b\u0430\u0434\u044b.<\/p>\n<p>PRF \u0434\u0430 \u043a\u04e9\u043b\u0456\u043a \u0436\u04af\u0440\u0433\u0456\u0437\u0435\u0434\u0456 <a href=\"https:\/\/www.progeriaresearch.org\/kk\/clinical-trials\/\"><strong>Progeria \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u044b\u043d\u044b\u04a3 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0441\u044b\u043d\u0430\u049b\u0442\u0430\u0440\u044b <\/strong><\/a>\u04d9\u043b\u0435\u0443\u0435\u0442\u0442\u0456 \u0435\u043c\u0434\u0435\u0443 \u04d9\u0434\u0456\u0441\u0442\u0435\u0440\u0456\u043d \u0441\u044b\u043d\u0430\u043f \u0436\u0430\u0442\u049b\u0430\u043d \u0436\u04d9\u043d\u0435 \u0431\u04af\u0433\u0456\u043d\u0433\u0456 \u043a\u04af\u043d\u0433\u0435 \u0434\u0435\u0439\u0456\u043d \u0442\u04e9\u0440\u0442 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0441\u044b\u043d\u0430\u049b\u0442\u044b \u049b\u0430\u0440\u0436\u044b\u043b\u0430\u043d\u0434\u044b\u0440\u044b\u043f, \u04af\u0439\u043b\u0435\u0441\u0442\u0456\u0440\u0434\u0456. <em>PRF \u0431\u0456\u0437\u0434\u0456 \u0435\u043c\u0434\u0435\u0443\u0433\u0435 \u0436\u0430\u049b\u044b\u043d\u0434\u0430\u0442\u0430\u0442\u044b\u043d \u043f\u0435\u0440\u0441\u043f\u0435\u043a\u0442\u0438\u0432\u0430\u043b\u044b \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0442\u0430\u0440\u0434\u044b \u0437\u0435\u0440\u0442\u0442\u0435\u0443\u0434\u0435 \u0435\u0448\u049b\u0430\u043d\u0434\u0430\u0439 \u0442\u0430\u0441 \u049b\u0430\u043b\u0434\u044b\u0440\u043c\u0430\u0439\u0434\u044b.<\/em><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_toggle title=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0493\u0430 \u043d\u0435 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435 \u0430\u043b\u0430\u0441\u044b\u0437?&quot; open_toggle_background_color=\u201d#f7f7f7\u2033 close_toggle_text_color=\u201d#ffffff\u201d close_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon1_5\u201dor admin_label=&quot;\u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0493\u0430 \u043d\u0435 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435 \u0430\u043b\u0430\u0441\u044b\u0437?&quot; _builder_version=\u201d4.24.3\u2033 title_text_color=\u201d#00b2e2\u2033 background_color=\u201d#ffffff\u201d custom_margin=\u201d10px||10px||true\u201d custom_padding=\u201d|50px||50px||true\u201d animation=toplion\u201d animation_intensity_slide=\u201d25%\u201d link_option_url_new_window=\u201don\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_all=\u201d0px\u201d global_colors_info=\u201d{}\u201d sticky_enabled=\u201d0<\/p>\n<div id=\"1488059409784-71ca0fef-3046\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<div class=\"vc_tta-panel-heading\">\n<div class=\"vc_tta-panel-heading\">\n<ul>\n<li><em><strong>\u049a\u0430\u0440\u0436\u044b\u043b\u044b\u049b \u04af\u043b\u0435\u0441 \u049b\u043e\u0441\u044b\u04a3\u044b\u0437<\/strong>.<\/em> \u049a\u0430\u0439\u044b\u0440\u044b\u043c\u0434\u044b\u043b\u044b\u049b PRF-\u043d\u044b\u04a3 \u049b\u04b1\u0442\u049b\u0430\u0440\u0443 \u0436\u04b1\u043c\u044b\u0441\u044b\u043d \u0436\u0430\u043b\u0493\u0430\u0441\u0442\u044b\u0440\u0443 \u04af\u0448\u0456\u043d \u04d9\u0440\u049b\u0430\u0448\u0430\u043d \u049b\u0430\u0436\u0435\u0442. \u049a\u0430\u0439\u044b\u0440\u044b\u043c\u0434\u044b\u043b\u044b\u049b \u0442\u044b\u043c \u0430\u0437 \u043d\u0435\u043c\u0435\u0441\u0435 \u0442\u044b\u043c \u04af\u043b\u043a\u0435\u043d \u0435\u043c\u0435\u0441 \u2013 \u04d9\u0440\u0431\u0456\u0440 \u0434\u043e\u043b\u043b\u0430\u0440 \u0435\u043c\u0434\u0435\u043b\u0443\u0434\u0456 \u0456\u0437\u0434\u0435\u0443\u0434\u0435 \u043c\u0430\u04a3\u044b\u0437\u0434\u044b! \u041e\u043d\u043b\u0430\u0439\u043d \u0441\u0430\u0434\u0430\u049b\u0430\u043b\u0430\u0440 \u043c\u044b\u043d\u0430 \u043c\u0435\u043a\u0435\u043d\u0436\u0430\u0439\u0434\u0430 \u049b\u0430\u0431\u044b\u043b\u0434\u0430\u043d\u0430\u0434\u044b <a href=\"https:\/\/www.progeriaresearch.org\/kk\/give\/\">\u0411\u0435\u0440\u0456\u04a3\u0456\u0437.<\/a>.<\/li>\n<\/ul>\n<ul>\n<li><strong><em>\u0423\u0430\u049b\u044b\u0442\u044b\u04a3\u044b\u0437\u0434\u044b \u0430\u044f\u043c\u0430\u04a3\u044b\u0437.<\/em><\/strong> \u0415\u0440\u0456\u043a\u0442\u0456\u043b\u0435\u0440 PRF \u0442\u0430\u0431\u044b\u0441\u044b \u04af\u0448\u0456\u043d \u0434\u0435 \u043c\u0430\u04a3\u044b\u0437\u0434\u044b. \u041d\u0430\u043d \u0441\u0430\u0442\u0443 \u043d\u0435\u043c\u0435\u0441\u0435 \u043a\u04e9\u043b\u0456\u043a \u0436\u0443\u0443 \u0441\u0438\u044f\u049b\u0442\u044b \u0430\u0440\u043d\u0430\u0439\u044b \u0456\u0441-\u0448\u0430\u0440\u0430 \u04e9\u0442\u043a\u0456\u0437\u0456\u04a3\u0456\u0437; \u043e\u0442\u0431\u0430\u0441\u044b\u043b\u0430\u0440\u0493\u0430 \u049b\u04b1\u0436\u0430\u0442\u0442\u0430\u0440\u0434\u044b \u0430\u0443\u0434\u0430\u0440\u0443; \u0436\u0456\u0431\u0435\u0440\u0443\u0433\u0435 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0456\u04a3\u0456\u0437 \u2013 \u0431\u0456\u0437 \u0441\u0456\u0437\u0433\u0435 \u043a\u0435\u0441\u0442\u0435\u04a3\u0456\u0437\u0433\u0435, \u043e\u0440\u043d\u0430\u043b\u0430\u0441\u049b\u0430\u043d \u0436\u0435\u0440\u0456\u04a3\u0456\u0437\u0433\u0435 \u0436\u04d9\u043d\u0435 \u0442\u0430\u043b\u0430\u043d\u0442\u0442\u0430\u0440\u044b\u04a3\u044b\u0437\u0493\u0430 \u0441\u04d9\u0439\u043a\u0435\u0441 \u043a\u0435\u043b\u0435\u0442\u0456\u043d \u043d\u04d9\u0440\u0441\u0435\u043d\u0456 \u0442\u0430\u0431\u0430\u043c\u044b\u0437! \u0411\u0456\u0437\u0434\u0456\u04a3 \u049b\u043e\u043d\u0430\u049b\u049b\u0430 \u0431\u0430\u0440\u044b\u04a3\u044b\u0437 <a href=\"https:\/\/www.progeriaresearch.org\/kk\/get-involved\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u049a\u0430\u0442\u044b\u0441\u044b\u04a3\u044b\u0437<\/a>\u00a0\u0431\u0435\u0442\u0456\u043d\u0434\u0435 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435 \u0430\u043b\u0430\u0442\u044b\u043d \u0431\u0430\u0440\u043b\u044b\u049b \u0436\u043e\u043b\u0434\u0430\u0440\u0434\u044b \u049b\u0430\u0440\u0430\u04a3\u044b\u0437.<\/li>\n<li><strong><em>\u049a\u043e\u0441\u044b\u043c\u0448\u0430 \u0430\u049b\u043f\u0430\u0440\u0430\u0442 \u0430\u043b\u044b\u04a3\u044b\u0437, \u0445\u0430\u0431\u0430\u0440\u0434\u044b \u0442\u0430\u0440\u0430\u0442\u044b\u04a3\u044b\u0437 \u0436\u04d9\u043d\u0435 \u0431\u0430\u0439\u043b\u0430\u043d\u044b\u0441\u044b\u04a3\u044b\u0437. <\/em><\/strong>PRF \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u0441\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u043c\u0435\u043d \u0436\u0430\u0441\u04e9\u0441\u043f\u0456\u0440\u0456\u043c\u0434\u0435\u0440\u0433\u0435 \u04b1\u0441\u044b\u043d\u0430\u0442\u044b\u043d \u043a\u04e9\u043f\u0442\u0435\u0433\u0435\u043d \u043c\u0430\u04a3\u044b\u0437\u0434\u044b \u0431\u0430\u0493\u0434\u0430\u0440\u043b\u0430\u043c\u0430\u043b\u0430\u0440 \u043c\u0435\u043d \u049b\u044b\u0437\u043c\u0435\u0442\u0442\u0435\u0440 \u0442\u0443\u0440\u0430\u043b\u044b \u043a\u04e9\u0431\u0456\u0440\u0435\u043a \u0431\u0456\u043b\u0433\u0456\u04a3\u0456\u0437 \u043a\u0435\u043b\u0435 \u043c\u0435? <strong>\u0411\u0456\u0437\u0434\u0456\u04a3 \u0432\u0435\u0431-\u0441\u0430\u0439\u0442\u0442\u044b \u049b\u0430\u0440\u0430\u04a3\u044b\u0437 <\/strong><a href=\"https:\/\/www.progeriaresearch.org\/kk\/\"><strong>progeriasearch.org<\/strong><\/a><em><br \/><\/em><em><br \/><\/em><em>\u0421\u0456\u0437 \u043a\u04e9\u043c\u0435\u043a\u0442\u0435\u0441\u0435 \u0430\u043b\u0430\u0442\u044b\u043d \u0431\u0456\u0440\u0435\u0443\u0434\u0456 \u0431\u0456\u043b\u0435\u0441\u0456\u0437 \u0431\u0435? <\/em>\u0414\u043e\u0441\u0442\u0430\u0440\u044b\u04a3\u044b\u0437\u0493\u0430, \u043e\u0442\u0431\u0430\u0441\u044b\u04a3\u044b\u0437\u0493\u0430 \u0436\u04d9\u043d\u0435 \u04d9\u0440\u0456\u043f\u0442\u0435\u0441\u0442\u0435\u0440\u0456\u04a3\u0456\u0437\u0433\u0435 PRF \u0436\u04d9\u043d\u0435 \u0431\u0456\u0437 \u0436\u0430\u0441\u0430\u0439\u0442\u044b\u043d \u049b\u04b1\u0442\u049b\u0430\u0440\u0443 \u0436\u04b1\u043c\u044b\u0441\u0442\u0430\u0440\u044b \u0442\u0443\u0440\u0430\u043b\u044b \u0430\u0439\u0442\u044b\u04a3\u044b\u0437! \u041a\u04e9\u0431\u0456\u043d\u0435\u0441\u0435 \u0430\u0434\u0430\u043c\u0434\u0430\u0440 \u04e9\u0437\u0434\u0435\u0440\u0456 \u0431\u0456\u043b\u0435\u0442\u0456\u043d \u0431\u0456\u0440\u0435\u0443\u0434\u0435\u043d \u04b1\u0441\u044b\u043d\u044b\u0441 \u0430\u043b\u0493\u0430\u043d \u0431\u043e\u043b\u0441\u0430, \u04b1\u0439\u044b\u043c\u0493\u0430 \u049b\u0430\u0439\u044b\u0440\u044b\u043c\u0434\u044b\u043b\u044b\u049b \u0436\u0430\u0441\u0430\u0443\u044b \u044b\u049b\u0442\u0438\u043c\u0430\u043b. \u0415\u043d\u0434\u0435\u0448\u0435 \u0431\u0456\u0437 \u04af\u0448\u0456\u043d \u0436\u0430\u049b\u0441\u044b \u0441\u04e9\u0437 \u0430\u0439\u0442\u044b\u04a3\u044b\u0437 \u0436\u04d9\u043d\u0435 \u0431\u0430\u0440\u043b\u044b\u0493\u044b\u043d\u0430 \u0431\u0456\u0437\u0434\u0456 \u0436\u0430\u043b\u0493\u0430\u0441\u0442\u044b\u0440\u0443\u0434\u044b \u0430\u0439\u0442\u044b\u04a3\u044b\u0437 <a href=\"https:\/\/twitter.com\/Progeria\">X<\/a>@progeria, \u0431\u0456\u0437\u0433\u0435 &quot;\u04b1\u043d\u0430\u0442\u0443&quot; <a href=\"https:\/\/www.facebook.com\/ProgeriaResearch\">Facebook<\/a>, \u0431\u0456\u0437\u0434\u0456\u04a3 \u0444\u043e\u0442\u043e\u043b\u0430\u0440\u0434\u044b \u049b\u0430\u0440\u0430\u04a3\u044b\u0437 <a href=\"https:\/\/www.instagram.com\/progeriaresearch\/?hl=en\">Instagram<\/a> @progeriaresearch, \u043a\u0435\u0439\u0431\u0456\u0440\u0435\u0443\u043b\u0435\u0440 \u0430\u0440\u049b\u044b\u043b\u044b Progeria \u049b\u0430\u0443\u044b\u043c\u0434\u0430\u0441\u0442\u044b\u0493\u044b\u043c\u0435\u043d \u0442\u0430\u043d\u044b\u0441\u044b\u04a3\u044b\u0437 <a href=\"http:\/\/www.youtube.com\/progeria123\">YouTube \u0431\u0435\u0439\u043d\u0435\u043b\u0435\u0440\u0456<\/a>, \u0436\u04d9\u043d\u0435 \u0431\u0456\u0437\u0431\u0435\u043d \u0442\u0456\u043a\u0435\u043b\u0435\u0439 \u0431\u0430\u0439\u043b\u0430\u043d\u044b\u0441\u044b\u04a3\u044b\u0437 <a href=\"mailto:info@progeriaresearch.org\">info@progeriaresearch.org<\/a>.\n<p><strong>\u0421\u0456\u0437\u0431\u0435\u043d \u0431\u0430\u0439\u043b\u0430\u043d\u044b\u0441\u0443\u0434\u044b \u0430\u0441\u044b\u0493\u0430 \u043a\u04af\u0442\u0435\u043c\u0456\u0437!<\/strong><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li style=\"list-style-type: none;\"><\/li>\n<\/ul>\n<h4 style=\"text-align: center;\"><span style=\"color: #000080;\"><strong><em>\u0414\u0410\u041c\u042b\u041d \u0411\u0406\u0420\u0413\u0415 \u0422\u0410\u0411\u0410\u041c\u042b\u0417!<\/em><\/strong><\/span><\/h4>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_text admin_label=\u201dreferences\u201d module_id=\u201dreferencefour\u201d _builder_version=\u201d4.24.3\u2033 _module_preset=\u201d\u04d9\u0434\u0435\u043f\u043a\u0456\u201d global_colors_info=\u201d{}\u201d]<\/p>\n<p><a href=\"#references\"><span style=\"color: #000080;\"><strong>\u0410\u043d\u044b\u049b\u0442\u0430\u043c\u0430\u043b\u0430\u0440<\/strong><\/span><\/a><\/p>\n<p>[1] \u0411\u0430\u0441\u049b\u0430 \u043f\u0440\u043e\u0433\u0435\u0440\u043e\u0438\u0434\u0442\u044b\u049b \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u0434\u0430\u0440\u0493\u0430 \u0412\u0435\u0440\u043d\u0435\u0440 \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b \u0436\u0430\u0442\u0430\u0434\u044b, \u043e\u043b \u00ab\u0435\u0440\u0435\u0441\u0435\u043a \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u00bb \u0434\u0435\u043f \u0442\u0435 \u0430\u0442\u0430\u043b\u0430\u0434\u044b, \u043e\u043b \u0436\u0430\u0441\u04e9\u0441\u043f\u0456\u0440\u0456\u043c\u0434\u0456\u043a \u0436\u0430\u0441\u049b\u0430 \u0434\u0435\u0439\u0456\u043d \u0431\u0430\u0441\u0442\u0430\u043b\u043c\u0430\u0439\u0434\u044b, \u04e9\u043c\u0456\u0440 \u0441\u04af\u0440\u0443 \u04b1\u0437\u0430\u049b\u0442\u044b\u0493\u044b 40 \u0436\u04d9\u043d\u0435 50 \u0436\u044b\u043b\u0434\u0430\u0440\u0493\u0430 \u0434\u0435\u0439\u0456\u043d.<\/p>\n<p><a href=\"https:\/\/www.progeriaresearch.org\/kk\/progeria-101faq\/ftn2\/\" name=\"_ftn1\">[2]<\/a> \u0422\u0456\u0440\u0456 \u0431\u0430\u043b\u0430\u043b\u0430\u0440 \u0442\u04b1\u0440\u0430\u0442\u044b\u043d \u0436\u0435\u0440 \u043a\u0430\u0440\u0442\u0430\u0441\u044b\u043d \u0430\u043b\u0443 \u04af\u0448\u0456\u043d https:\/\/www.progeriaresearch.org\/meet-the-kids\/ \u0441\u0430\u0439\u0442\u044b\u043d\u0430 \u04e9\u0442\u0456\u04a3\u0456\u0437.<\/p>\n<p><a href=\"#ftn3\" name=\"_ftn1\">[3]<\/a> \u00ab\u0410 \u043b\u0430\u043c\u0438\u043d\u0430\u0441\u044b\u043d\u0434\u0430 \u049b\u0430\u0439\u0442\u0430\u043b\u0430\u043d\u0430\u0442\u044b\u043d \u0434\u0435 \u0436\u0430\u04a3\u0430 \u043d\u04af\u043a\u0442\u0435\u043b\u0456\u043a \u043c\u0443\u0442\u0430\u0446\u0438\u044f\u043b\u0430\u0440 \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b\u043d \u0442\u0443\u0434\u044b\u0440\u0430\u0434\u044b\u00bb, \u0422\u0430\u0431\u0438\u0493\u0430\u0442, \u0442\u043e\u043c. 423, 2003 \u0436\u044b\u043b\u0493\u044b 15 \u043c\u0430\u043c\u044b\u0440.<\/p>\n<p><a href=\"#ftn4\" name=\"_ftn1\">[4]<\/a> 2021 \u0410\u043c\u0435\u0440\u0438\u043a\u0430\u043d\u0434\u044b\u049b \u0436\u04af\u0440\u0435\u043a \u049b\u0430\u0443\u044b\u043c\u0434\u0430\u0441\u0442\u044b\u0493\u044b\u043d\u044b\u04a3 \u0436\u04af\u0440\u0435\u043a \u0430\u0443\u0440\u0443\u043b\u0430\u0440\u044b \u0436\u04d9\u043d\u0435 \u0438\u043d\u0441\u0443\u043b\u044c\u0442 \u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u043a\u0430\u0441\u044b.<\/p>\n<p><a href=\"#ftn5\" name=\"_ftn1\">[5]<\/a> \u0413\u043e\u0440\u0434\u043e\u043d \u041b.\u0411., \u041a\u043b\u0435\u0439\u043d\u043c\u0430\u043d ME \u0436\u04d9\u043d\u0435 \u0442.\u0431. \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b \u0431\u0430\u0440 \u0431\u0430\u043b\u0430\u043b\u0430\u0440\u0434\u0430 \u0444\u0430\u0440\u043d\u0435\u0437\u0438\u043b\u0442\u0440\u0430\u043d\u0441\u0444\u0435\u0440\u0430\u0437\u0430 \u0442\u0435\u0436\u0435\u0433\u0456\u0448\u0456\u043d\u0456\u04a3 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0441\u044b\u043d\u0430\u0493\u044b. Proc Natl Acad Sci US A. 2012 9 \u049b\u0430\u0437\u0430\u043d;109(41):16666-71. doi: 10.1073\/pnas.1202529109. Epub 2012, 24 \u049b\u044b\u0440\u043a\u04af\u0439\u0435\u043a.<\/p>\n<p><a href=\"#ftn6\" name=\"_ftn1\">[6]<\/a> \u0413\u043e\u0440\u0434\u043e\u043d \u041b.\u0411., \u0428\u0430\u043f\u043f\u0435\u043b\u043b \u041d, \u041c\u0430\u0441\u0441\u0430\u0440\u043e \u0414\u0436, \u0442.\u0431. \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b \u0431\u0430\u0440 \u043d\u0430\u0443\u049b\u0430\u0441\u0442\u0430\u0440\u0434\u0430 \u04e9\u043b\u0456\u043c-\u0436\u0456\u0442\u0456\u043c \u0434\u0435\u04a3\u0433\u0435\u0439\u0456\u043c\u0435\u043d \u0435\u043c\u0434\u0435\u043b\u043c\u0435\u0433\u0435\u043d \u0436\u04d9\u043d\u0435 \u041b\u043e\u043d\u0430\u0444\u0430\u0440\u043d\u0438\u0431\u043f\u0435\u043d \u0435\u043c\u0434\u0435\u0443 \u049b\u0430\u0443\u044b\u043c\u0434\u0430\u0441\u0442\u044b\u0493\u044b. \u0416\u0410\u041c\u0410. 2018;319(16):1687\u20131695 \u0436\u0436.<\/p>\n<p><a href=\"#ftn7\" name=\"_ftn1\">[7]<\/a>\u00a0\u0413\u043e\u0440\u0434\u043e\u043d, \u041b.\u0411., \u041d\u043e\u0440\u0440\u0438\u0441, \u0412., \u0425\u0430\u043c\u0440\u0435\u043d, \u0421.,\u00a0<em>\u0442.\u0431<\/em>. \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b \u0431\u0430\u0440 \u043d\u0430\u0443\u049b\u0430\u0441\u0442\u0430\u0440\u0434\u0430\u0493\u044b \u043f\u043b\u0430\u0437\u043c\u0430\u043b\u044b\u049b \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d: \u0438\u043c\u043c\u0443\u043d\u043e\u043b\u043e\u0433\u0438\u044f\u043b\u044b\u049b \u0442\u0430\u043b\u0434\u0430\u0443\u0434\u044b \u0434\u0430\u043c\u044b\u0442\u0443 \u0436\u04d9\u043d\u0435 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0431\u0430\u0493\u0430\u043b\u0430\u0443.\u00a0<em>\u0410\u0439\u043d\u0430\u043b\u044b\u043c<\/em>, 2023.<\/p>\n<p><a href=\"#ftn8\" name=\"_ftn1\">[8]<\/a> \u0413\u043e\u0440\u0434\u043e\u043d \u041b.\u0411., \u0411\u0430\u0441\u0441\u043e \u0421 \u0436\u04d9\u043d\u0435 \u0442.\u0431. \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f\u043b\u044b\u049b \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b\u043d\u0434\u0430\u0493\u044b \u0441\u044b\u043d\u0438 \u0430\u043e\u0440\u0442\u0430 \u0441\u0442\u0435\u043d\u043e\u0437\u044b\u043d\u0430 \u0430\u0440\u0430\u043b\u0430\u0441\u0443.\u00a0<em>\u0410\u043b\u0434\u044b\u04a3\u0493\u044b. \u0416\u04af\u0440\u0435\u043a-\u049b\u0430\u043d \u0442\u0430\u043c\u044b\u0440\u043b\u0430\u0440\u044b. \u041c\u0435\u0434.<\/em>\u00a011:1356010. doi: 10.3389\/fcvm.2024.1356010 (2024).<\/p>\n<p><a href=\"#ftn9\" name=\"_ftn1\">[9]<\/a> Koblan, LW, Erdos, MR, Wilson, C. et al. In vivo \u0431\u0430\u0437\u0430\u043b\u044b\u049b \u04e9\u04a3\u0434\u0435\u0443 \u0442\u044b\u0448\u049b\u0430\u043d\u0434\u0430\u0440\u0434\u0430\u0493\u044b \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b\u043d \u049b\u04b1\u0442\u049b\u0430\u0440\u0430\u0434\u044b. \u0422\u0430\u0431\u0438\u0493\u0430\u0442 589, 608\u2013614 (2021).<\/p>\n<p><a href=\"#ftn10\" name=\"_ftn1\">[10]<\/a> Erdos, MR, Cabral, WA, Tavarez, UL et al. \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b \u04af\u0448\u0456\u043d \u043c\u0430\u049b\u0441\u0430\u0442\u0442\u044b \u0430\u043d\u0442\u0438\u0441\u0435\u043d\u0441 \u0442\u0435\u0440\u0430\u043f\u0438\u044f\u043b\u044b\u049b \u0442\u04d9\u0441\u0456\u043b\u0456. \u041d\u0430\u0442 \u041c\u0435\u0434 (2021). https:\/\/doi.org\/10.1038\/s41591-021-01274-0<\/p>\n<p><a href=\"#ftn11\" name=\"_ftn1\">[11]<\/a> \u041f\u0443\u0442\u0442\u0430\u0440\u0430\u0434\u0436\u0443, \u041c., \u0414\u0436\u0435\u043a\u0441\u043e\u043d, \u041c., \u041a\u043b\u0435\u0439\u043d, \u0421. \u0436\u04d9\u043d\u0435 \u0442.\u0431. \u0416\u04af\u0439\u0435\u043b\u0456 \u0441\u043a\u0440\u0438\u043d\u0438\u043d\u0433 \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b \u04af\u0448\u0456\u043d \u0442\u0435\u0440\u0430\u043f\u0435\u0432\u0442\u0456\u043a \u0430\u043d\u0442\u0438\u0441\u0435\u043d\u0441 \u043e\u043b\u0438\u0433\u043e\u043d\u0443\u043a\u043b\u0435\u043e\u0442\u0438\u0434\u0442\u0435\u0440\u0434\u0456 \u0430\u043d\u044b\u049b\u0442\u0430\u0439\u0434\u044b. \u041d\u0430\u0442 \u041c\u0435\u0434 (2021). https:\/\/doi.org\/10.1038\/s41591-021-01262-4<\/p>\n<p><a href=\"#ftn12\" name=\"_ftn1\">[12]<\/a> \u041a\u0430\u043d\u0433 \u0421\u041c, \u042e\u043d \u041c\u0425 \u0436\u04d9\u043d\u0435 \u0442.\u0431. \u041f\u0440\u043e\u0433\u0435\u0440\u0438\u043d\u0438\u043d, \u043e\u04a3\u0442\u0430\u0439\u043b\u0430\u043d\u0434\u044b\u0440\u044b\u043b\u0493\u0430\u043d \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d-\u043b\u0430\u043c\u0438\u043d \u0410 \u0431\u0430\u0439\u043b\u0430\u043d\u044b\u0441\u0442\u044b\u0440\u0443 \u0442\u0435\u0436\u0435\u0433\u0456\u0448\u0456, \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b\u043d\u044b\u04a3 \u043c\u0435\u0440\u0437\u0456\u043c\u0456\u043d\u0435\u043d \u0431\u04b1\u0440\u044b\u043d \u049b\u0430\u0440\u0442\u0430\u044e \u0444\u0435\u043d\u043e\u0442\u0438\u043f\u0442\u0435\u0440\u0456\u043d \u0436\u0430\u049b\u0441\u0430\u0440\u0442\u0430\u0434\u044b. <em>\u041a\u043e\u043c\u043c\u0443\u043d \u0411\u0438\u043e\u043b<\/em>. 2021 \u0436\u044b\u043b\u0493\u044b 4 \u049b\u0430\u04a3\u0442\u0430\u0440; 4(1):5.<a href=\"#_ftnref8\" name=\"_ftn1\"><\/a><\/p>\n<p><a href=\"#ftn13\" name=\"_ftn1\">[13]<\/a> \u0413\u043e\u0440\u0434\u043e\u043d, \u041b.\u0411., \u041d\u043e\u0440\u0440\u0438\u0441, \u0412., \u0425\u0430\u043c\u0440\u0435\u043d, \u0421., \u0442.\u0431. \u0425\u0430\u0442\u0447\u0438\u043d\u0441\u043e\u043d-\u0413\u0438\u043b\u0444\u043e\u0440\u0434 \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u044f \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u044b \u0431\u0430\u0440 \u043d\u0430\u0443\u049b\u0430\u0441\u0442\u0430\u0440\u0434\u0430\u0493\u044b \u043f\u043b\u0430\u0437\u043c\u0430\u043b\u044b\u049b \u043f\u0440\u043e\u0433\u0435\u0440\u0438\u043d: \u0438\u043c\u043c\u0443\u043d\u043e\u043b\u043e\u0433\u0438\u044f\u043b\u044b\u049b \u0442\u0430\u043b\u0434\u0430\u0443\u0434\u044b \u0434\u0430\u043c\u044b\u0442\u0443 \u0436\u04d9\u043d\u0435 \u043a\u043b\u0438\u043d\u0438\u043a\u0430\u043b\u044b\u049b \u0431\u0430\u0493\u0430\u043b\u0430\u0443. <em>\u0410\u0439\u043d\u0430\u043b\u044b\u043c<\/em>, 2023<\/p>\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=\u201d1\u2033 module_class=\u201dfooter\u201d _builder_version=\u201d4.2. background_color=\u201d#29327a\u201d \u0442\u0435\u04a3\u0448\u0435\u043b\u0435\u0442\u0456\u043d_\u043c\u0430\u0440\u0436\u0430=\u201d-2px|||||\u201d custom_padding=\u201d0|0px|0|0px|false|false\u201d z_index_tablet=\u201d500\u2033 border_width_top=\u201d12px\u201d border_color_top=\u201d#00b2e2\u2033 global_module=\u201d133\u2033 \u049b\u04b1\u043b\u044b\u043f\u0442\u0430\u0443\u043b\u044b=\u201doff\u201d global_colors_info][_\u201d][_\u201db column_structure=\u201d1_3,1_3,1_3\u2033 disabled_on=\u201d\u049b\u043e\u0441\u0443|\u049b\u043e\u0441\u0443\u043b\u044b\u201d _builder_version=\u201d4.21.0\u2033 _module_preset=\u201ddefault\u201d min_height=\u201d277px\u201d custom_margin=\u201d|20px|30px|\u201d|false custom_padding=\u201d0px|30px|0px||false|false\u201d disabled=\u201don\u201d global_colors_info=\u201d{}\u201d][et_pb_column_inner type=\u201d1_3\u2033 saved_specialty_column_type=\u201d3_4\u2033 _builder_version=\u201d4.2\u2033 _builder_version=\u201d4.2\u201dduult_set.\u201d global_colors_info=\u201d{}\u201d][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/08\/Startbanner-1.png\u201d title_text=\u201dStartbanner\u201d url=\u201dhttps:\/\/ www.gravoc.com\/\u201dalign=\u201dright\u201d _builder_version=\u201d4.21.0\u2033 _module_preset=\u201ddefault\u201d custom_margin=\u201d|-50px||20px|false|false\u201d global_colors_info=\u201d{}\u201d][\/et_pb_image][\/et_pb_column_inner][et_in\u2033n\u201c1\u201d saved_specialty_column_type=\u201d3_4\u2033 _builder_version=\u201d4.21.0\u2033 _module_preset=\u201ddefault\u201d global_colors_info=\u201d{}\u201d][\/et_pb_column_inner][et_pb_column_inner type=\u201d1_3\u2033 saved_specialty_column_type=\u201d3_4\u2033 _builder_version=\u201d4.21.0\u2033 _module_preset=\u201ddefault\u201d global_colors_info=\u201d{}\u201d][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/07\/RFRFinish.png\u201d title_text=\u201dRFRFinish\u201d _builder_version=\u201d4.21.0\u2033 _module_preset=\u201d\u04d9\u0434\u0435\u043f\u043a\u0456\u201d custom_margin=|\u201d|20px |-50px|\u0436\u0430\u043b\u0493\u0430\u043d|\u0436\u0430\u043b\u0493\u0430\u043d\u00bb global_colors_info=\u201d{}\u201d][\/et_pb_image][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row column_structure=\u201d1_4,1_4,1_2\u2033 make_equal=\u201don\u201d module_class=\u201det_pb_row_inner=\u201det_pb_row_inner=\u201det_pb_row_inner=6\u201det_pb_row_full.\u201d width=\u201d89%\u201d width_tablet=\u201d80%\u201d width_phone=\u201d\u201d width_last_edited=\u201d\u0436\u04b1\u043c\u044b\u0441 \u04af\u0441\u0442\u0435\u043b\u0456\u043d\u0434\u0435\u201d max_width=\u201d89%\u201d max_width_tablet=\u201d80%\u201d max_width_phone=\u201d\u201d max_width_laston_edited=\u201dskript_edited z_index_tablet=\u201d500\u2033 make_fullwidth=\u201don\u201d width_unit=\u201doff\u201d custom_width_percent=\u201d100%\u201d global_colors_info=\u201d{}\u201d][et_pb_column type=\u201d1_4\u2033 _builder_version=\u201d4.16\u2033 _builder_version=\u201d4.16\u2033|\u201d|\u0442\u0430\u04a3\u0434\u0430\u043c\u0430\u043b\u044b global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_cta button_url=\u201dhttps:\/\/www.progeriaresearch.org\/newsletter-signup\/\u201d button_text=\u201d\u049a\u0430\u0437\u0456\u0440 \u0442\u0456\u0440\u043a\u0435\u043b\u0443\u201d admin_label=\u201d\u0416\u0430\u04a3\u0430\u043b\u044b\u049b\u0442\u0430\u0440\u0493\u0430 \u0442\u0456\u0440\u043a\u0435\u043b\u0443\u201d module_class =&quot;sign-btn&quot; _builder_version=\u201d4.16\u2033 header_font_size=\u201d25px\u201d background_color=\u201d#29327a\u201d animation_style=\u201dslide\u201d animation_direction=\u201dleft\u201d animation_intensity_slide=\u201d25%\u201dsize header_font=\u201d header_font_size_phone=\u201d30px\u201d header_font_size_last_edited=\u201don|desktop\u201d z_index_tablet=\u201d500\u2033 border_radii=\u201don|25px|25px|25px|25px\u201d global_colors_info=\u201d{}\u201d button_bg_verable=\u201d button_bg_color__hover=\u201d#8fd2ed\u201d button_border_color__hover_enabled=\u201d\u049b\u043e\u0441\u0443\u043b\u044b\u201d]<\/p>\n<h2>\u0422\u0456\u0440\u043a\u0435\u043b\u0443<\/h2>\n<h2>\u0411\u0456\u0437\u0434\u0456\u04a3 \u04af\u0448\u0456\u043d<\/h2>\n<h2>\u0410\u049b\u043f\u0430\u0440\u0430\u0442\u0442\u044b\u049b \u0431\u044e\u043b\u043b\u0435\u0442\u0435\u043d\u044c!<\/h2>\n<p>[\/et_pb_cta][\/et_pb_column][et_pb_column type=\u201d1_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_cta button_url=\u201dhttps:\/\/progeriaresearch.donorsupport.co\/-\/XZHJVWZR\u201d button_text=\u201d\u049a\u0430\u0437\u0456\u0440 \u049b\u0430\u0439\u044b\u0440\u044b\u043c\u0434\u044b\u043b\u044b\u049b \u0436\u0430\u0441\u0430\u0443\u201d admin_label=\u201d\u0415\u043c\u0434\u0456 \u0431\u0456\u0440\u0433\u0435 \u0442\u0430\u0431\u0430\u043c\u044b\u0437! \u00bb module_class=\u201dsign-btn\u201d _builder_version=\u201d4.16\u2033 header_font_size=\u201d25px\u201d background_color=\u201d#29327a\u201d animation_style=\u201dslide\u201d animation_direction=\u201dleft\u201d animation_intensity_slide=\u201d2TP1=3 header_font_size_tablet=\u201d\u201d header_font_size_phone=\u201d30px\u201d header_font_size_last_edited=\u201don|desktop\u201d body_font_size_tablet=\u201d\u201d body_font_size_phone=\u201d\u201d body_font_size_last_edited=\u201dxtop=\u201dx_tb_desk=\u201dx=0\u201ddesk border_radii=\u201don|25px|25px|25px|25px\u201d global_colors_info=\u201d{}\u201d button_bg_color__hover_enabled=\u201don\u201d button_bg_color__hover=\u201d#8fd2ed\u201d button_border_color__hover_enabled=\u201d\u049b\u043e\u0441\u0443\u043b\u044b\u201d]<\/p>\n<h2>\u0411\u0456\u0440\u0433\u0435, \u0431\u0456\u0437<\/h2>\n<h2><em>\u0411\u041e\u041b\u0410\u0414\u042b<\/em><\/h2>\n<h2>\u0435\u043c\u0456\u043d \u0442\u0430\u043f!<\/h2>\n<p>[\/et_pb_cta][\/et_pb_column][et_pb_column type=\u201d1_2\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2024\/02\/2024-strip-footer-strip-.png\u201d title_text=&quot;2024 \u0436\u043e\u043b\u0430\u0493\u044b \u0442\u04e9\u043c\u0435\u043d\u0433\u0456 \u0434\u0435\u0440\u0435\u043a\u0442\u0435\u043c\u0435 \u0436\u043e\u043b\u0430\u0493\u044b&quot; _builder_version=\u201d4.24.0\u2033 _module_preset=\u201ddefault\u201d custom_margin=\u201d35px||||false|false\u201d global_colors_info=\u201d{}\u201d][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_se]<\/p>","protected":false},"excerpt":{"rendered":"<p>[et_pb_section fb_built=\u201d1\u2033 fullwidth=\u201don\u201d disabled_on=\u201doff|off|off\u201d _builder_version=\u201d4.16\u2033 border_width_bottom=\u201d55px\u201d border_color_bottom=\u201d#29327a\u201d global_colors_info=\u201d{p}b _builder_version=\u201d4.16\u2033 title_font_size=\u201d55\u2033 background_color=\u201d#29327a\u201d background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/About-Header_position\u201d background_position\u201djp custom_padding=\u201d11.5vw||11.5vw||true\u201d custom_padding_tablet=\u201d\u201d custom_padding_phone=\u201d|56px||\u201d custom_padding_last_edited=\u201don|desktop\u201d title_font_size_tablet=\u201d45px\u201d title_font_size_phone=\u201d40px\u201d title_font_size_last_edited=\u201don|phone\u201d z_index_tablet=\u201d500\u2033 custom_css_main_round=\u201dTPCenter=\u201dbackg18- !\u043c\u0430\u04a3\u044b\u0437\u0434\u044b;\u201d global_colors_info=\u201d{}\u201d] Progeria 101 \/ \u0416\u049a\u0421 [\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=\u201d1\u2033 use_custom_gutter=\u201don\u201d gutter_width=\u201d1\u2033 \u043c\u0430\u043c\u0430\u043d\u0434\u044b\u049b=\u201don\u201d padding_3\u201d px_3\u201d padding_left_2=\u201d35px\u201d padding_2_tablet=\u201d|||0px\u201d padding_2_phone=\u201d|||0px\u201d padding_2_last_edited=\u201don|desktop\u201d module_class_1=\u201dsidebar-secondary-nav\u201d module_class=_\u201dhandprint=6\u201dg.\u2033ilder. background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/blue-handprint-only.png\u201d parallax=\u201don\u201d parallax_method=\u201doff\u201d inner_width=\u201d100%\u201d inner_max_width=\u201d100% \u00bb custom_padding=\u201d0|0px|54px|0px|false|false\u201d z_index_tablet=\u201d500\u2033 border_width_top=\u201d10px\u201d border_color_top=\u201d#8fd2ed\u201d use_custom_width=\u201don\u201d width_unit=\u201doff\u201d custom_width_percent=\u201d\u2026\u201d10<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"\t\t\t\t[vc_row][vc_column][vc_custom_heading text=\"Progeria 101\/FAQ\" font_container=\"tag:h1|text_align:center\" use_theme_fonts=\"yes\"][vc_column_text]\r\n<h1>What is Progeria?<\/h1>\r\n<p align=\"left\">Hutchinson-Gilford Progeria Syndrome \u201cProgeria\u201d or \u201cHGPS\u201d is a rare, fatal genetic condition characterized by an appearance of\u00a0accelerated aging in children*.\u00a0 Its name is derived from Greek and means \"prematurely old.\"\u00a0 While there are different forms of Progeria<a href=\"https:\/\/www.progeriaresearch.org\/progeria_101.html#_ftn1\">*<\/a>, the classic type is Hutchinson-Gilford Progeria Syndrome, which was named after the doctors who first described it in England: in 1886 by Dr. Jonathan Hutchinson, and in 1897 by Dr. Hastings Gilford.<\/p>\r\n\r\n<h1>Did you know?<\/h1>\r\n<p align=\"left\">Progeria is caused by a tiny point mutation in a child's DNA, a one-letter typo in the billions of letters that make up the chromosomal book.<\/p>\r\n<a href=\"https:\/\/www.progeriaresearch.org\/progeria_101.html#_ftnref1\">*<\/a> Other Progeroid syndromes include Werner syndrome, also known as \u201cadult progeria\u201d which does not have an onset until the late teen years, with a lifespan into the 40\u2019s and 50\u2019s.\u00a0<a href=\"https:\/\/www.wernersyndrome.org\/index.html\">Click here <\/a>for information on Werner Syndrome[\/vc_column_text][vc_column_text]\r\n<h1>How common is Progeria?<\/h1>\r\nProgeria affects approximately 1 in 20 million people.\u00a0 There are an estimated 350-400 children living with Progeria worldwide at any one time.\u00a0 It affects both sexes equally and all races.\u00a0 Since The Progeria Research Foundation was created in 1999, we have discovered children with Progeria living in 52 countries and speaking 32 languages.\r\n\r\nFor a map of where living children reside, please go to our <a href=\"https:\/\/www.progeriaresearch.org\/meet_the_kids\/\">Meet the Kids<\/a> page.[\/vc_column_text][vc_column_text]\r\n<h1>What are the features of Progeria?<\/h1>\r\nAlthough they are usually born looking healthy, most children with Progeria begin to display many characteristics of Progeria within the first 2 years of life.\u00a0 Signs of Progeria include growth failure, loss of body fat and hair, aged-looking skin and stiffness of joints.\u00a0 As children get older, they suffer from atherosclerosis, cardiovascular (heart) disease and sometimes have strokes.\u00a0 The children have a remarkably similar appearance despite differing ethnic backgrounds. Children with Progeria die of heart failure at an average age of fourteen years.[\/vc_column_text][vc_column_text]\r\n<h1>What is the cause of Progeria?<\/h1>\r\n[caption id=\"\" align=\"alignnone\" width=\"142\"]<img src=\"https:\/\/www.progeriaresearch.org\/assets\/images\/medical_images\/progeria-cell.jpg\" alt=\"\" width=\"142\" height=\"115\" \/> Progeria Cell Nucleus.[\/caption]\r\n\r\nHGPS is caused by a mutation in the gene called <em>LMNA<\/em> (pronounced \u201clamin-a\u201d). The <em>LMNA<\/em> gene produces the lamin A protein which is the structural scaffolding that holds the nucleus of a cell together. The abnormal lamin A protein that causes Progeria is called <em>progerin<\/em>.\u00a0 Progerin makes the nucleus unstable.\u00a0 That cellular instability leads to the process of premature aging and disease in Progeria.\r\n\r\nPRF was the driving force behind finding the gene responsible for Progeria. A group of leading scientists from PRF\u2019s Genetics Consortium was able to isolate the Progeria gene, and in April 2003, PRF led the announcement reported in the top scientific journal <em>Nature<\/em><a href=\"https:\/\/www.progeriaresearch.org\/progeria_101.html#_ftn1\">v<\/a>.\r\n\r\n<em>\u201cIsolating the Progeria gene is a major achievement for the medical research community,\u201d<\/em> said Dr. Francis Collins, Director of the National Institutes of Health and senior discoverer of the Progeria gene, \u201c<em>The discovery not only gives hope to children and families affected by<\/em>\r\n\r\n<em>Progeria, but also may shed light on the phenomenon of aging and cardiovascular disease.\u201d<\/em>\r\n\r\n<a href=\"https:\/\/www.progeriaresearch.org\/progeria_101.html#_ftnref1\">v<\/a> \u201cRecurrent de novo point mutations in lamin A cause Hutchinson-Gilford Progeria Syndrome\u201d, \u00a0<em>Nature<\/em>, \u00a0Vol. 423, \u00a0May 15, 2003.[\/vc_column_text][vc_column_text]\r\n<h1>What does Progeria have to do with aging?<\/h1>\r\nWe now know that there is a biological overlap between children with Progeria and the general aging population.\u00a0 We all make a little bit of <em>progerin<\/em>, the disease-causing protein in Progeria. We make much less progerin than children with Progeria, but the progerin builds up over a lifetime and may be partly responsible for aspects of aging such as atherosclerosis.\u00a0 Progerin is also linked to telomere dysfunction.\u00a0 Telomeres are proteins that play a major role in cellular aging.\r\n\r\nChildren with Progeria are genetically predisposed to premature, progressive heart disease. Death occurs almost exclusively due to widespread heart disease, the leading cause of death worldwide.<a href=\"https:\/\/www.progeriaresearch.org\/progeria_101.html#_ftn1\">+<\/a>\u00a0 Thus, there is clearly a tremendous need for research in Progeria.\u00a0 Finding a cure for Progeria will not only help these children, but may provide keys for treating millions of adults with heart disease and stroke associated with the natural aging process.\r\n\r\n<strong>\u00a0<\/strong><a href=\"https:\/\/www.progeriaresearch.org\/progeria_101.html#_ftnref1\">+<\/a> \u00a02016 American Heart Association Heart Disease and Stroke Statistics[\/vc_column_text][vc_column_text css=\".vc_custom_1495542400027{background-color: #ffffff !important;}\"]\r\n<h1>Is Progeria passed down from parent to child?<\/h1>\r\nHGPS is not usually passed down in families. The gene change is almost always a chance occurrence that is extremely rare. Children with other types of \u201cprogeroid\u201d syndromes which are not HGPS may have diseases that are passed down in families. However, HGPS is a \u201csporadic autosomal dominant\u201d mutation \u2013 sporadic because it is a new change in that family, and dominant because only one copy of the gene needs to be changed in order to have the syndrome. For parents who have never had a child with Progeria, the chances of having a child with Progeria are 1 in 20 million. But for parents who have already had a child with Progeria, the chances of it happening again to those parents is much higher \u2013 about 2-3%. Why the increase? This is due to a condition called \u201cmosaicism\u201d, where a parent has the genetic mutation for Progeria in a small proportion of their cells, but does not have Progeria. Prenatal testing is available to look for the <em>LMNA <\/em>genetic change that causes HGPS.[\/vc_column_text][vc_column_text css=\".vc_custom_1508524802591{background-color: #ffffff !important;}\"]\r\n<h1>How is Progeria diagnosed?<\/h1>\r\n<p align=\"left\">Now that the gene mutation has been identified, The Progeria Research Foundation has a <a href=\"https:\/\/www.progeriaresearch.org\/diagnostic_testing.html\"><strong>Diagnostic Testing Program<\/strong><\/a>.\u00a0 We can now look at the specific genetic change, or mutation, in the Progeria gene that leads to HGPS. After an initial clinical evaluation (looking at the child\u2019s appearance and medical records), a sample of the child\u2019s blood will be tested for Progeria.\u00a0 PRF provides a definitive, scientific way to diagnose the children<em>.<\/em> This leads to more accurate and earlier diagnoses so the children can receive proper care.<\/p>\r\n[\/vc_column_text][vc_column_text css=\".vc_custom_1555429336142{background-color: #ffffff !important;}\"]\r\n<h1>What is PRF doing to help children with Progeria?<\/h1>\r\n<p align=\"left\"><img class=\"alignright size-full wp-image-4731\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/HBenglish-front.jpg\" alt=\"\" width=\"200\" height=\"257\" \/>PRF is also driving Progeria clinical drug trials testing potential treatments.\u00a0 To date, PRF has funded and co-coordinated three clinical trials. Please refer to our <a href=\"https:\/\/www.progeriaresearch.org\/clinical_trial.html\"><strong>clinical drug trials <\/strong><\/a>section for more details.\u00a0History was made in September 2012 with the discovery that the drug involved in the first clinical trial, a farnesyltransferase inhibitor or FTI , is the first-ever treatment for Progeria \u2666.\u00a0 PRF continues to explore other promising drugs that will bring us to a cure for Progeria. <strong>\u00a0<\/strong>The Progeria Research Foundation funds medical research aimed at developing treatments and a cure for Progeria.\u00a0 PRF also has its own <a href=\"https:\/\/www.progeriaresearch.org\/cell_tissue_bank\/\"><strong>Cell & Tissue Bank<\/strong><\/a> that provides the biological materials researchers need to conduct their experiments.\u00a0 Additionally, PRF has established a <a href=\"https:\/\/www.progeriaresearch.org\/medical-database\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Medical & Research Database<\/strong><\/a> to supply physicians and families with medical recommendations for cardiac care, nutrition and other medical issues to help children and adults with Progeria have a better quality of life.\u00a0 We continue to analyze medical records of children and adults with Progeria so that we can provide information on how best to medically help those with Progeria, and provide clues towards potential new treatments.\u00a0 PRF \u00a0has also published <a href=\"https:\/\/www.progeriaresearch.org\/patient_care.html\"><strong>The Progeria Handbook<\/strong><\/a> for families and doctors. \u00a0From basic health facts to daily care recommendations to extensive treatment guidelines, the handbook helps answer many questions for people with Progeria throughout the world. The\u00a02019 2<sup>nd<\/sup>\u00a0edition of the\u00a0Handbook is available in English\u00a0and\u00a0Spanish;\u00a0the first edition is also available in Portuguese.<\/p>\r\n\u2666 Proc Natl Acad Sci U S A. 2012 Sep 24. [Epub ahead of print][\/vc_column_text][vc_column_text css=\".vc_custom_1510406154104{background-color: #ffffff !important;}\"]\r\n<h1>What can you do to help children with Progeria?<\/h1>\r\n<ul>\r\n \t<li><em><strong>Make a financial contribution<\/strong>.<\/em> Donations are needed to continue the vital work of PRF.\u00a0 No donation is too little or too big \u2013 every dollar counts in our quest for a cure! Online donations are accepted on our <a href=\"https:\/\/weblink.donorperfect.com\/PRFGivingTuesday2019\" target=\"_blank\" rel=\"noopener noreferrer\">Donation Form<\/a>.<\/li>\r\n<\/ul>\r\n<ul>\r\n \t<li><strong><em>Donate your time.<\/em><\/strong> Volunteers are also important to PRF\u2019s success.\u00a0 Hold a special event like a bake sale or letter writing campaign; translate documents for the families; help with a mailing \u2013 we\u2019ll find something for you to do that fits your schedule, location and talents! Visit our <a href=\"https:\/\/www.progeriaresearch.org\/get_involved\/\">Get Involved<\/a> page to see all the ways you can help.<\/li>\r\n<\/ul>\r\n<ul>\r\n \t<li><em><strong>Donate in-kind services or items<\/strong>.<\/em> Do you own a printing or office supply business? Are you a computer whiz that can help with our <a href=\"https:\/\/twitter.com\/Progeria\" target=\"_blank\" rel=\"noopener noreferrer\">Twitter<\/a>, <a href=\"https:\/\/www.facebook.com\/home.php#!\/ProgeriaResearch\" target=\"_blank\" rel=\"noopener noreferrer\">Facebook<\/a>, web site and\/or other on-line presence?\u00a0 Do you have a business background in non-profit development?\u00a0 These are just some of the many types of talents and connections PRF needs. The more tasks we can get accomplished on a pro bono basis, the more money we can devote to research!<\/li>\r\n<\/ul>\r\n<ul>\r\n \t<li><strong><em>Spread the word and tap into your connections.<\/em><\/strong><em> Do you know anyone who can help? <\/em>Tell your friends, family and colleagues about PRF and the amazing work we\u2019re doing! Many times, people are more likely to donate to an organization if they\u2019ve gotten a recommendation from someone they know. So put in a good word for us and tell everyone to visit our web site at <a href=\"https:\/\/www.progeriaresearch.org\/\">www.progeriaresearch.org<\/a> , follow us on <a href=\"https:\/\/twitter.com\/Progeria\" target=\"_blank\" rel=\"noopener noreferrer\">Twitter<\/a>, \u201clike\u201d us on <a href=\"https:\/\/www.facebook.com\/home.php#!\/ProgeriaResearch\" target=\"_blank\" rel=\"noopener noreferrer\">Facebook<\/a>, and contact us at <a href=\"mailto:info@progeriaresearch.org\">info@progeriaresearch.org<\/a><\/li>\r\n<\/ul>\r\n<p align=\"center\"><em>TOGETHER WE WILL FIND THE CURE!<\/em><\/p>\r\n[\/vc_column_text][\/vc_column][\/vc_row]\t\t","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-763","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Progeria 101 FAQ | The Progeria Research 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