{"id":10065,"date":"2020-03-23T14:52:19","date_gmt":"2020-03-23T14:52:19","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=10065"},"modified":"2020-12-14T17:58:16","modified_gmt":"2020-12-14T22:58:16","slug":"application-to-fda-for-lonafarnib-approval-is-done","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/kn\/2020\/03\/23\/application-to-fda-for-lonafarnib-approval-is-done\/","title":{"rendered":"\u0cb2\u0ccb\u0ca8\u0cbe\u0cab\u0cb0\u0ccd\u0ca8\u0cbf\u0cac\u0ccd \u0c85\u0ca8\u0cc1\u0cae\u0ccb\u0ca6\u0ca8\u0cc6\u0c97\u0cbe\u0c97\u0cbf FDA \u0c97\u0cc6 \u0c85\u0cb0\u0ccd\u0c9c\u0cbf \u0cb8\u0cb2\u0ccd\u0cb2\u0cbf\u0cb8\u0cc1\u0cb5\u0cc1\u0ca6\u0cc1 \u0caa\u0cc2\u0cb0\u0ccd\u0ca3\u0c97\u0cca\u0c82\u0ca1\u0cbf\u0ca6\u0cc6!"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.22&#8243;][et_pb_row _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;FDA&#8221; _builder_version=&#8221;4.3.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;]<\/p>\n<p style=\"font-weight: 400;\"><strong><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-10068  alignleft\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/03\/FDA-300x265.jpg\" alt=\"\" width=\"206\" height=\"182\" \/>Application to FDA for lonafarnib approval is COMPLETE!\u00a0\u00a0\u00a0<\/strong><\/p>\n<p style=\"font-weight: 400;\">During an otherwise difficult time for our world, I am happy to share a bright spot: Eiger BioPharmaceuticals has completed submission of a New Drug Application (NDA), seeking approval &#8211; in Europe and the US &#8211; of the drug lonafarnib as a first-ever treatment for Progeria.<\/p>\n<p style=\"font-weight: 400;\">This submission is the culmination of twelve years of research data and four clinical trials, all funded by PRF and made possible by the courageous children and their families, as well as PRF\u2019s wonderful community of donors.<\/p>\n<p style=\"font-weight: 400;\">You can read more about this exciting news\u00a0<a href=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/03\/PRF-Lonafarnib-NDA-Completion-Press-Release-final-PDF-3-23-20.pdf\" target=\"_blank\" rel=\"noopener noreferrer\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/03\/PRF-Lonafarnib-NDA-Completion-Press-Release-final-PDF-3-23-20.pdf&amp;source=gmail&amp;ust=1585060548571000&amp;usg=AFQjCNE_6Qu8yUr9CDSuYvEVeGJXwXtlYA\">here<\/a>.<\/p>\n<p style=\"font-weight: 400;\">Our hope is that this drug will be approved, enabling these children and young adults to access lonafarnib \u2013 which has been shown to give them stronger hearts and longer lives &#8211; by prescription, instead of through a clinical trial.<\/p>\n<p style=\"font-weight: 400;\">While 2020 has started off as a difficult year for many, we are happy to share a bit of good news with you. All of us at The Progeria Research Foundation have worked tirelessly to make a meaningful impact on the lives of children and young adults with Progeria.<\/p>\n<p style=\"font-weight: 400;\">THANK YOU ALL for supporting the research that not only has brought us to this pivotal point, but also allows us to continue working to discover new drugs that will ultimately cure these extraordinary children.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0ca8\u0cae\u0ccd\u0cae \u0c9c\u0c97\u0ca4\u0ccd\u0ca4\u0cbf\u0c97\u0cc6 \u0c95\u0cb7\u0ccd\u0c9f\u0c95\u0cb0\u0cb5\u0cbe\u0ca6 \u0cb8\u0cae\u0caf\u0ca6\u0cb2\u0ccd\u0cb2\u0cbf, \u0caa\u0ccd\u0cb0\u0c95\u0cbe\u0cb6\u0cae\u0cbe\u0ca8\u0cb5\u0cbe\u0ca6 \u0cb8\u0ccd\u0ca5\u0cb3\u0cb5\u0ca8\u0ccd\u0ca8\u0cc1 \u0cb9\u0c82\u0c9a\u0cbf\u0c95\u0cca\u0cb3\u0ccd\u0cb3\u0cb2\u0cc1 \u0ca8\u0cbe\u0cb5\u0cc1 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\u0caa\u0ccd\u0cb0\u0cca\u0c9c\u0cc6\u0cb0\u0cbf\u0caf\u0cbe \u0c9a\u0cbf\u0c95\u0cbf\u0ca4\u0ccd\u0cb8\u0cc6<\/p>","protected":false},"author":2,"featured_media":10068,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-10065","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Application to FDA for lonafarnib approval is COMPLETE! - The Progeria Research Foundation<\/title>\n<meta name=\"description\" content=\"During an otherwise difficult time for our world, we are happy to share a bright spot: Eiger BioPharmaceuticals has completed submission of a New Drug Application (NDA), seeking approval - in Europe and the US - of the drug lonafarnib as a first-ever treatment for Progeria.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/kn\/2020\/03\/23\/application-to-fda-for-lonafarnib-approval-is-done\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Application to FDA for lonafarnib approval is COMPLETE! - The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"During an otherwise difficult time for our world, we are happy to share a bright spot: Eiger BioPharmaceuticals has completed submission of a New Drug Application (NDA), seeking approval - in Europe and the US - of the drug lonafarnib as a first-ever treatment for Progeria.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.progeriaresearch.org\/kn\/2020\/03\/23\/application-to-fda-for-lonafarnib-approval-is-done\/\" \/>\n<meta property=\"og:site_name\" content=\"The Progeria Research Foundation\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ProgeriaResearch\/\" \/>\n<meta property=\"article:published_time\" content=\"2020-03-23T14:52:19+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-12-14T22:58:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/03\/FDA.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"600\" \/>\n\t<meta property=\"og:image:height\" content=\"529\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Karen Betournay\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@Progeria\" \/>\n<meta name=\"twitter:site\" 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