{"id":1905,"date":"2017-05-09T20:24:40","date_gmt":"2017-05-09T20:24:40","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?page_id=1905"},"modified":"2023-09-21T12:37:08","modified_gmt":"2023-09-21T16:37:08","slug":"2001-first-ever-nih-prf-workshop","status":"publish","type":"page","link":"https:\/\/www.progeriaresearch.org\/ko\/2001-first-ever-nih-prf-workshop\/","title":{"rendered":"2001\ub144, \ucd5c\ucd08\uc758 NIH-PRF \uc6cc\ud06c\uc20d"},"content":{"rendered":"<p><strong>\ud569\ub3d9 \uc6cc\ud06c\uc20d\uc774 \ud070 \uc131\uacf5\uc744 \uac70\ub450\uc5c8\uc2b5\ub2c8\ub2e4!<\/strong><\/p>\n<div><strong>NIH-PRF \uc6cc\ud06c\uc20d 2001<\/strong><br \/>\n<strong>\ubca0\ub370\uc2a4\ub2e4, MD 2001\ub144 11\uc6d4 28-29\uc77c<\/strong><\/div>\n<p>\ud504\ub85c\uac8c\ub9ac\uc544 \uc5f0\uad6c \uc7ac\ub2e8\uc740 \ubbf8\uad6d \uad6d\ub9bd\ubcf4\uac74\uc6d0(NIH)\uacfc \uacf5\ub3d9\uc73c\ub85c 2001\ub144 11\uc6d4 28\uc77c\uacfc 29\uc77c\uc5d0 \uba54\ub9b4\ub79c\ub4dc\uc8fc \ubca0\ub370\uc2a4\ub2e4\uc5d0\uc11c \ud5c8\uce5c\uc2a8-\uae38\ud3ec\ub4dc \ud504\ub85c\uac8c\ub9ac\uc544 \uc99d\ud6c4\uad70\uc5d0 \uad00\ud55c \ucd5c\ucd08\uc758 \uad6d\uc81c \uc6cc\ud06c\uc20d\uc744 \uac1c\ucd5c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p>46\uba85\uc758 \uacfc\ud559\uc790\ub4e4\uc740 \uc2ec\uc7a5\ud559\uacfc \uc8fd\uc0c1\uacbd\ud654, \ubf08 \ub300\uc0ac, \ubd84\uc790\u00b7\uc138\ud3ec\u00b7\ubc1c\uc0dd \uc0dd\ubb3c\ud559, \uba74\uc5ed\ud559, \ub0b4\ubd84\ube44\ud559, \uce58\uacfc, \ub178\ub144\uc758\ud559 \ubc0f \uc720\uc804\ud559\uc744 \ud3ec\ud568\ud55c \ub2e4\uc591\ud55c \uc784\uc0c1 \ubc0f \uc5f0\uad6c \uae30\ubc18 \uc804\ubb38 \ubd84\uc57c\uc758 \ub9ac\ub354\ub4e4\uc774 \ud55c \ud504\ub808\uc820\ud14c\uc774\uc158\uc5d0 \uae4a\uc740 \uad00\uc2ec\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4.<\/p>\n<div><strong>\uc6cc\ud06c\uc20d \ud558\uc774\ub77c\uc774\ud2b8<\/strong><\/div>\n<div><strong>\ubca0\ub370\uc2a4\ub2e4, MD 2001\ub144 11\uc6d4 28-29\uc77c<\/strong><\/div>\n<div>Hutchinson-Gilford Progeria \uc99d\ud6c4\uad70\uc5d0 \uad00\ud55c \uccab \ubc88\uc9f8 PRF-NIH \uacf5\ub3d9 \uc6cc\ud06c\uc20d\uc740 \ub2e4\uc74c\uc5d0\uc11c \ud6c4\uc6d0\ud588\uc2b5\ub2c8\ub2e4. <strong>\ud504\ub85c\uac8c\ub9ac\uc544 \uc5f0\uad6c \uc7ac\ub2e8 <\/strong>\uadf8\ub9ac\uace0 <strong>\uad6d\ub9bd\ubcf4\uac74\uc6d0<\/strong>, \uadf8\ub9ac\uace0 \uc9c0\uc6d0\ub428<strong>\uad6d\ub9bd\ub178\ud654\uc5f0\uad6c\uc18c<\/strong>, \uadf8 <strong>\ud76c\uadc0\uc9c8\ud658 \uc0ac\ubb34\uc18c<\/strong> \uadf8\ub9ac\uace0 <strong>\uc5d8\ub9ac\uc2a8 \uc758\ub8cc\uc7ac\ub2e8<\/strong>.<\/div>\n<div>\ub610\ud55c \ub2e4\uc74c\uc744 \ud3ec\ud568\ud55c \uad6d\ub9bd\ubcf4\uac74\uc6d0\uc758 \uc5ec\ub7ec \ub2e4\ub978 \uad6c\uc131 \uc694\uc18c\uc758 \ub300\ud45c\uc790\ub4e4\ub3c4 \ucc38\uc5ec\ud588\uc2b5\ub2c8\ub2e4.<\/div>\n<ul>\n<li><strong>\uad6d\ub9bd \uc544\ub3d9 \uac74\uac15 \ubc0f \uc778\uac04 \uac1c\ubc1c \uc5f0\uad6c\uc18c<\/strong><\/li>\n<li><strong>\uad6d\ub9bd \uc2ec\uc7a5, \ud3d0 \ubc0f \ud608\uc561 \uc5f0\uad6c\uc18c<\/strong><\/li>\n<li><strong>\uad6d\ub9bd \uad00\uc808\uc5fc \ubc0f \uadfc\uace8\uaca9\uacc4 \ubc0f \ud53c\ubd80 \uc9c8\ud658 \uc5f0\uad6c\uc18c<\/strong><\/li>\n<li><strong>\uad6d\ub9bd\uc554\uc5f0\uad6c\uc18c<\/strong><\/li>\n<li><strong>\uad6d\ub9bd\uc778\uac04\uc720\uc804\uccb4\uc5f0\uad6c\uc18c<\/strong><\/li>\n<\/ul>\n<p>\uc6cc\ud06c\uc20d\uc758 \uad81\uadf9\uc801\uc778 \ubaa9\ud45c\ub294 \uc5ec\ub7ec \uc7a5\uae30 \uc2dc\uc2a4\ud15c\uc758 \ub2e8\uc11c\ub97c \uc870\uc0ac\ud558\uc5ec \ud5c8\uce5c\uc2a8-\uae38\ud3ec\ub4dc \ud504\ub85c\uac8c\ub9ac\uc544 \uc99d\ud6c4\uad70\uc758 \uadfc\ubcf8 \uc6d0\uc778(\uc720\uc804\uc801, \uc0dd\ud654\ud559\uc801, \uc0dd\ub9ac\ud559\uc801)\uc5d0 \ub300\ud55c \uc815\ubcf4\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\ub294 \uc720\ub9dd\ud55c \uc5f0\uad6c \ubd84\uc57c\ub97c \ub17c\uc758\ud558\uace0 \uc2dd\ubcc4\ud558\ub294 \uac83\uc774\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uc6cc\ud06c\uc20d\uc758 \uc2dc\uc791 \ubd80\ubd84\uc740 \ub2e4\uc74c\uacfc \uac19\uc774 \uc9c4\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. <strong>\uc870\uc9c0 M. \ub9c8\ud2f4, MD<\/strong>, \ubcd1\ub9ac\ud559 \uad50\uc218, \uc720\uc804\ud559 \uacb8\uc784 \uad50\uc218, \uc6cc\uc2f1\ud134 \uc2dc\uc560\ud2c0\uc5d0 \uc788\ub294 \uc6cc\uc2f1\ud134 \ub300\ud559\uad50 \uc758\uacfc\ub300\ud559 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \uc5f0\uad6c \uc13c\ud130 \uc18c\uc7a5. \ub9c8\ud2f4 \ubc15\uc0ac\ub294 \uc131\uc778 \ub178\ud654 \uc99d\ud6c4\uad70\uc778 \ubca0\ub974\ub108 \uc99d\ud6c4\uad70 \uc720\uc804\uc790\ub97c \ubc1c\uacac\ud558\ub294 \uc5f0\uad6c \ud504\ub85c\uc81d\ud2b8\ub97c \uc9c0\ud718\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub294<strong>\ud504\ub85c\uac8c\ub9ac\uc544 \uc99d\ud6c4\uad70\uc758 \uacf5\ud1b5 \uc8fc\uc81c<\/strong>.<\/p>\n<p>\uc548 <strong>\ud504\ub85c\uac8c\ub9ac\uc544 \uac1c\uc694 \ubc0f \ud604\uc7ac\uae4c\uc9c0\uc758 \uc5f0\uad6c \uacb0\uacfc \uc694\uc57d<\/strong> \uadf8 \ub2e4\uc74c\uc5d0 \ub2e4\uc74c\uc5d0 \uc758\ud574 \uc81c\uc2dc\ub418\uc5c8\uc2b5\ub2c8\ub2e4. <strong>W. \ud14c\ub4dc \ube0c\ub77c\uc6b4, MD, PhD<\/strong>, \uc778\uac04 \uc720\uc804\ud559\uacfc \uc758\uc7a5, George A. Jervis Clinic \uc774\uc0ac, \ub274\uc695 Staten Island, NY\uc5d0 \uc788\ub294 \ubc1c\ub2ec \uc7a5\uc560 \uae30\ucd08 \uc5f0\uad6c\uc18c\uc758 \uc784\uc2dc \uc774\uc0ac. Brown \ubc15\uc0ac\ub294 Hutchinson-Gilford Progeria \uc99d\ud6c4\uad70\uc758 \uc120\ub3c4\uc801 \uc804\ubb38\uac00\ub85c \uc5ec\uaca8\uc9c0\uba70 PRF \uc774\uc0ac\ud68c\uc640 \uc758\ud559 \uc5f0\uad6c \uc704\uc6d0\ud68c\uc758 \ud65c\ub3d9\uc801\uc778 \uba64\ubc84\uc785\ub2c8\ub2e4.<\/p>\n<p>\ub2e4\uc74c\ub0a0, <strong>\uc564\uc11c\ub2c8 \ubc14\uc774\uc2a4, MD<\/strong>\ud638\uc8fc \uc2dc\ub4dc\ub2c8 \ub300\ud559\uad50 \ubd84\uc790 \ubc0f \uc138\ud3ec \uc0dd\uba85 \uacfc\ud559\ubd80 \ubd84\uc790 \uc0dd\uba85 \uacf5\ud559 \uac00\uc0c1 \ud559\uacfc\uc758 \ubd84\uc790 \uc0dd\uba85 \uacf5\ud559 \ud504\ub85c\uadf8\ub7a8 \ucc45\uc784\uc790\uc774\uc790 \uc900\uad50\uc218\uac00 \uc790\uc2e0\uc758 \uc5f0\uad6c \uacb0\uacfc\ub97c \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. <strong>\ubc30\uc591\ub41c \ud5c8\uce5c\uc2a8-\uae38\ud3ec\ub4dc \ud504\ub85c\uac8c\ub9ac\uc544 \ud53c\ubd80 \uc12c\uc720\uc544\uc138\ud3ec\uc758 \ub2f9\ud654.<\/strong> Weiss \ubc15\uc0ac\ub294 \uc9c0\ub09c 12\ub144 \ub3d9\uc548 \ud504\ub85c\uac8c\ub9ac\uc544\uc5d0 \uad00\ud55c \uac00\uc7a5 \ub9ce\uc740 \uc218\uc758 \ub3d9\ub8cc \ud3c9\uac00 \uae30\ucd08 \uacfc\ud559 \ub17c\ubb38\uc744 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uc2e0\uc911\ud55c \ud3c9\uac00 <strong>\ubf08 \ubcd1\ub9ac\ud559<\/strong>, \uac80\ud1a0\ub428 <strong>\ud504\ub808\ub370\ub9ad \uc0e4\ud53c\ub85c, MD<\/strong> \ubcf4\uc2a4\ud134 \uc18c\uc544\ubcd1\uc6d0 \uc815\ud615\uc678\uacfc \uc870\uad50\uc218\ub294 \uc870\uae30 \ubf08 \ub178\ud654\uc640 \uace8\ub2e4\uacf5\uc99d\ubcf4\ub2e4\ub294 \ube44\uc815\uc0c1\uc801\uc778 \ubf08 \ubc1c\ub2ec\uc774 \uc774 \uc99d\ud6c4\uad70\uacfc \ud568\uaed8 \ub098\ud0c0\ub09c\ub2e4\uace0 \uc81c\uc548\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub294 \uc774\ub97c \ucd94\uac00 \uc5f0\uad6c\uac00 \ud544\uc694\ud55c \uc601\uc5ed\uc73c\ub85c \ud655\uc778\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\ud788\uc54c\ub8e8\ub860\uc0b0\uacfc \ud504\ub85c\uac8c\ub9ac\uc544\uc758 \uad00\uacc4<\/strong>, PRF \uc790\uae08 \uc9c0\uc6d0 \ud504\ub85c\uc81d\ud2b8\uac00 \ub2e4\uc74c\uc5d0 \ubc1c\ud45c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. <strong>Leslie B. Gordon, MD, PhD<\/strong>, \ub85c\ub4dc\uc544\uc77c\ub79c\ub4dc \uc8fc \ud504\ub85c\ube44\ub358\uc2a4\uc5d0 \uc788\ub294 Hasbro Children&#039;s Hospital\uc758 \uc18c\uc544\uacfc \uac15\uc0ac\uc774\uc790 \ub9e4\uc0ac\ucd94\uc138\uce20 \uc8fc \ubcf4\uc2a4\ud134\uc5d0 \uc788\ub294 Tufts University School of Medicine\uc758 \uc5f0\uad6c\uc6d0. Gordon \ubc15\uc0ac\ub294 Progeria\uc758 \ubcd1\ub9ac \uba54\ucee4\ub2c8\uc998, \ud2b9\ud788 \uc2ec\uc7a5\ubcd1\uc774 \ud788\uc54c\ub8e8\ub860\uc0b0\uacfc \uad00\ub828\uc774 \uc788\ub2e4\ub294 \uc774\uc804\uc5d0 \ubc1c\ud45c\ub41c \uc5f0\uad6c \uacb0\uacfc\ub97c \ud14c\uc2a4\ud2b8\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\ud1a0\ub9c8\uc2a4 \uc640\uc774\ud2b8, \ubc15\uc0ac<\/strong>, \uc6cc\uc2f1\ud134\uc8fc \uc2dc\uc560\ud2c0\uc5d0 \uc788\ub294 Hope Heart Institute\uc758 \ud608\uad00\uc0dd\ubb3c\ud559\uacfc \ubcd1\ub9ac\ud559 \uad50\uc218\uac00 \ub17c\uc758\ud588\uc2b5\ub2c8\ub2e4. <strong>\uc8fd\uc0c1\uacbd\ud654\uc99d \ubd84\uc57c\uc758 \ub2e8\uc11c.<\/strong> \uc640\uc774\ud2b8 \ubc15\uc0ac\ub294 \ud504\ub85c\uac8c\ub9ac\uc544\uc5d0 \uc218\ubc18\ub418\ub294 \ud608\uad00 \uc9c8\ud658\uc5d0\uc11c \ud504\ub85c\ud14c\uc624\uae00\ub9ac\uce78\uacfc \uc138\ud3ec\uc678 \uae30\uc9c8\uc758 \uc7a0\uc7ac\uc801\uc778 \uc5ed\ud560\uc5d0 \ub300\ud574 \uc124\uba85\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\ub808\uc2ac\ub9ac \uc2a4\ubb34\ud2b8, MD<\/strong> \uadf8 \ub2e4\uc74c\uc5d0\ub294 \ub17c\uc758\ud588\ub2e4 <strong>\uc2ec\ud608\uad00\uacc4\ub85c\ubd80\ud130\uc758 \ub2e8\uc11c.<\/strong> \uc2a4\ubb34\ud2b8 \ubc15\uc0ac\ub294 \uc18c\uc544 \uc2ec\uc7a5\ub0b4\uacfc \uc804\ubb38\uc758\uc774\uc790 \uc18c\uc544 \uc2ec\ud608\uad00 \uc720\uc804\ud559 \ub4f1\ub85d\ubd80 \ucc45\uc784\uc790\uc774\uba70 \ud604\uc7ac \ub9e4\uc0ac\ucd94\uc138\uce20\uc8fc \ubcf4\uc2a4\ud134\uc5d0 \uc788\ub294 \uc18c\uc544 \ubcd1\uc6d0\uc5d0\uc11c \uc2ec\uadfc\ubcd1\uacfc \uc2ec\uc7a5 \uc774\uc2dd \uc784\uc0c1 \uc11c\ube44\uc2a4\uc5d0 \ucc38\uc5ec\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub140\ub294 \ub610\ud55c \ud558\ubc84\ub4dc \uc758\ub300\uc5d0\uc11c \uc18c\uc544\uacfc \uac15\uc0ac\ub85c \uc77c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub140\ub294 \uc2ec\ud608\uad00 \ubcd1\ubcc0\uc758 \uc2e4\uc81c \ubcd1\ub9ac\ud559\uc774 \uc798 \ud2b9\uc131\ud654\ub418\uc9c0 \uc54a\uc558\ub2e4\ub294 \uc99d\uac70\ub97c \uc81c\uc2dc\ud588\uc2b5\ub2c8\ub2e4. \ud504\ub85c\uac8c\ub9ac\uc544\uc758 \ud608\uad00 \ubcc0\ud654\uc640 \uc77c\ubc18\uc801\uc778 \uc2ec\uc7a5 \uc9c8\ud658\uc758 \uc2e0\uc911\ud55c \ube44\uad50\ub294 \ucd94\uac00 \uc5f0\uad6c \ubd84\uc57c\ub85c \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\ub808\uc2ac\ub9ac \uace0\ub4e0 \ubc15\uc0ac<\/strong> \uadf8 \ub2e4\uc74c\uc5d0 \ucc3d\uc870\ub97c \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4 <strong>PRF \uc138\ud3ec\uc740\ud589<\/strong> \uadf8\ub9ac\uace0 <strong>\ud504\ub85c\uac8c\ub9ac\uc544 \ub370\uc774\ud130\ubca0\uc774\uc2a4<\/strong> \uc774 \uc5b4\ub9b0\uc774\ub4e4\uc758 \uc815\ub9ac\ub41c \uc790\uc138\ud55c \uc758\ub8cc \uc815\ubcf4\ub97c \ubd84\uc11d\ud558\uace0, \uc758\ub8cc \uc804\ubb38\uac00, \uc758\ud559 \uc5f0\uad6c\uc790, \uc870\ub85c\uc99d\uc774 \uc788\ub294 \uc5b4\ub9b0\uc774\uc758 \uac00\uc871\uc774 HGPS\uc758 \ud2b9\uc131\uacfc \uc8fd\uc0c1\uacbd\ud654\uc99d, \uad00\uc808\uc5fc\uacfc \uac19\uc740 \ub2e4\ub978 \uc9c8\ubcd1\uc758 \ud2b9\uc131\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \ud1b5\ucc30\ub825\uc744 \uc5bb\uae30 \uc704\ud574 \uc0ac\uc6a9\ud560 \uc218 \uc788\ub294 \ub9ac\uc18c\uc2a4\ub85c \uc0ac\uc6a9\ub420 \uac83\uc785\ub2c8\ub2e4. \ub450 \ud504\ub85c\uc81d\ud2b8 \ubaa8\ub450 \ucc38\uac00\uc790\ub4e4\uc758 \ud070 \uad00\uc2ec\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc6cc\ud06c\uc20d \ub9c8\uc9c0\ub9c9\uc5d0 \uc694\uc57d \ubc0f \uc77c\ubc18 \ud1a0\ub860\uc5d0\uc11c George Martin \ubc15\uc0ac\ub294 &quot;\uc774 \ub370\uc774\ud130\ubca0\uc774\uc2a4\ub294 \uc544\ub9c8\ub3c4 \uc774 \ud68c\uc758\uc5d0\uc11c \ub098\uc628 \uac00\uc7a5 \uc911\uc694\ud55c \uac83\uc77c \uac83\uc774\uace0, Leslie\uc640 \uadf8\ub140\uc758 \ub3d9\ub8cc\ub4e4\uc774 \uadf8\ub807\uac8c \ud55c \uac83\uc744 \ucd95\ud558\ud569\ub2c8\ub2e4.&quot;\ub77c\uace0 \ub9d0\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\uc870\ub2c8 J. \uc704\ud1a0, MD, PhD<\/strong>\ud39c\uc2e4\ubca0\uc774\ub2c8\uc544\uc8fc \ud544\ub77c\ub378\ud53c\uc544\uc5d0 \uc788\ub294 Jefferson Medical College\uc758 \ud53c\ubd80\uacfc \ubc0f \ud53c\ubd80\uc0dd\ubb3c\ud559\uacfc \uad50\uc218\uc774\uc790 \ud559\uacfc\uc7a5, Jefferson \ubd84\uc790\uc758\ud559 \uc5f0\uad6c\uc18c \uc18c\uc7a5\uc774 \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4. <strong>\ud53c\ubd80\ub85c\ubd80\ud130\uc758 \ub2e8\uc11c<\/strong> \uadf8\ub9ac\uace0 \ucd08\uae30 \uacbd\ud654\uc99d\uacfc \uac19\uc740 \ud53c\ubd80 \ubcc0\ud654\uc5d0 \ub300\ud55c \uad00\ucc30. Uitto \ubc15\uc0ac\uc758 \uc5f0\uad6c\ub294 \ud53c\ubd80 \ub178\ud654\uc758 \ubd84\uc790\uc801 \uba54\ucee4\ub2c8\uc998\uc5d0 \ucd08\uc810\uc744 \ub9de\ucda5\ub2c8\ub2e4.<\/p>\n<p><strong>\uac8c\ub9ac E. \uc640\uc774\uc988, \ubc15\uc0ac<\/strong>\ub8e8\uc774\uc9c0\uc560\ub098 \uc8fc\ub9bd \ub300\ud559\uad50 \uc218\uc758\uacfc\ub300\ud559 \ube44\uad50 \uc0dd\ubb3c\uc758\ud559\uacfc \uad50\uc218\uc774\uc790 \ud559\uacfc\uc7a5\uc740 \uc7a0\uc7ac\ub825\uc5d0 \ub300\ud574 \ub17c\uc758\ud588\uc2b5\ub2c8\ub2e4. <strong>\ud504\ub85c\uac8c\ub9ac\uc544 \ud658\uc790\uc758 \uce58\uc544 \ub3cb\uae30 \uc9c0\uc5f0 \uc6d0\uc778<\/strong> \uc640\uc774\uc988 \ubc15\uc0ac\ub294 \uce58\uc544 \ubd84\ucd9c \ubb38\uc81c\uac00 HGPS\uc758 \uacb0\ud569 \uc870\uc9c1 \ubc0f \ubf08 \uacb0\ud568\uc758 \uc77c\ubd80\uc77c \uc218 \uc788\ub2e4\uace0 \uc81c\uc548\ud569\ub2c8\ub2e4.<\/p>\n<p>\uc6cc\ud06c\uc20d\uc758 \ud2b9\ud788 \ud765\ubbf8\ub85c\uc6b4 \ubd80\ubd84\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4. <strong>\uc720\uc804\ud559 \uc6d0\ud0c1\ud68c\uc758 \ud1a0\ub860<\/strong>, \uc8fc\ub3c4\ud558\uc5ec <strong>\ud504\ub79c\uc2dc\uc2a4 \ucf5c\ub9b0\uc2a4 \ubc15\uc0ac<\/strong>, National Human Genome Research Institute \uc18c\uc7a5. \ucc38\uac00\uc790 7\uba85\uc774 \uc9c8\ubcd1\uc758 \uc0dd\ubb3c\ud559\uc801 \uae30\ucd08\ub97c \ud0d0\uad6c\ud558\uace0 Progeria \uc720\uc804\uc790\ub97c \ucc3e\uae30 \uc704\ud55c \ud604\uc7ac \ubc0f \ubbf8\ub798 \uc5f0\uad6c \uc804\ub7b5\uc744 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. Progeria\uc758 \ubd84\uc790\uc801 \uae30\ucd08\ub294 \uc54c\ub824\uc9c0\uc9c0 \uc54a\uc558\uc73c\uba70 \ub3cc\uc5f0\ubcc0\uc774 \uc720\uc804\uc790\ub294 \ud655\uc778\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. \uc6cc\ud06c\uc20d\uc5d0 \ucc38\uc11d\ud55c \uc5f0\uad6c \uadf8\ub8f9 \uc911 3\uac1c\ub294 Progeria\uc758 \uc720\uc804\uc801 \uae30\ucd08\ub97c \ud655\ub9bd\ud558\uae30 \uc704\ud55c \ud504\ub85c\uc81d\ud2b8\ub97c \uc801\uadf9\uc801\uc73c\ub85c \uc9c4\ud589\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. NIH\ub294 \ud604\uc7ac \uc774 \uadf8\ub8f9 \uc911 \ud558\ub098\uc5d0 \uc790\uae08\uc744 \uc9c0\uc6d0\ud558\uace0 \uc788\uc73c\uba70 PRF\ub294 \ub2e4\ub978 \ub450 \uadf8\ub8f9\uc5d0 \uc790\uae08\uc744 \uc9c0\uc6d0\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<div><strong>\ud504\ub79c\uc2dc\uc2a4 \ucf5c\ub9b0\uc2a4 \ubc15\uc0ac<\/strong> \uadf8\ub9ac\uace0 \uad6d\ub9bd\uc778\uac04\uc720\uc804\uccb4\uc5f0\uad6c\uc18c\uc758 \uadf8\uc758 \uc5f0\uad6c\uc9c4\uc740 \uc720\uc804\uc790\ub97c \ucc3e\uae30 \uc704\ud574 \uc0c1\ub3d9\uc811\ud569\uc131 \ub9e4\ud551\uc744 \uc0ac\uc6a9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. <strong>\uc874 \uc138\ub514\ube44 \ubc15\uc0ac<\/strong> \ub85c\ub4dc\uc544\uc77c\ub79c\ub4dc \uc8fc \ud504\ub85c\ube44\ub358\uc2a4\uc5d0 \uc788\ub294 \ube0c\ub77c\uc6b4 \ub300\ud559\uc5d0\uc11c\ub294 \uccb4\uc138\ud3ec \ubcf4\uc644\uc744 \uc0ac\uc6a9\ud558\uc5ec \ud504\ub85c\uac8c\ub9ac\uc544\ub97c \ud2b9\uc131\ud654\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. <strong>\ud1a0\ub9c8\uc2a4 \uae00\ub85c\ubc84 \ubc15\uc0ac<\/strong> \ubbf8\uc2dc\uac04 \ub300\ud559\uc758 \uc5f0\uad6c\ud300\uc740 HGPS \uc138\ud3ec\uc758 \uc720\uc804\uccb4 \uc720\uc9c0\uc5d0 \ub300\ud55c \uad6c\uccb4\uc801\uc778 \uc601\ud5a5\uc744 \uc870\uc0ac\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/div>\n<p><strong>\uc870\ub2c8 J. \uc704\ud1a0, MD, PhD<\/strong>, \uc800\uc790\ub294 \ubd84\uc790 \uc758\ud559 \ud2b8\ub80c\ub4dc(Vol. 8 No. 4, 2002\ub144 4\uc6d4) 4\uc6d4\ud638 155-157\ucabd\uacfc \ub0b4\ubd84\ube44\ud559 \ubc0f \ub300\uc0ac \ud2b8\ub80c\ub4dc(Vol. 13 No. 4, 2002\ub144 5\/6\uc6d4) 5\uc6d4\ud638 140-141\ucabd\uc5d0\uc11c \uc6cc\ud06c\uc20d \uc694\uc57d\uc744 \uc791\uc131\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<div><em>\ud504\ub85c\uac8c\ub9ac\uc544 \uc5f0\uad6c \uc7ac\ub2e8\uc740 \uc9c4\uc2ec\uc73c\ub85c \uac10\uc0ac\ub4dc\ub9bd\ub2c8\ub2e4.<\/em> <strong>\uc5d8\ub9ac\uc2a8 \uc758\ub8cc\uc7ac\ub2e8<\/strong> <em>PRF-NIH \uacf5\ub3d9 \ud5c8\uce5c\uc2a8-\uae38\ud3ec\ub4dc \uc6cc\ud06c\uc20d\uc5d0 \ub300\ud55c \uc9c0\uc6d0\uc5d0 \uac10\uc0ac\ub4dc\ub9bd\ub2c8\ub2e4.<\/em><\/div>\n<div><strong>\ucc38\uac00\uc790\uc758 \uc124\uba85\uc801 \uc694\uc57d<\/strong><\/div>\n<p><strong>Scott D. Berns, MD, MPH <\/strong><br \/>\nMarch of Dimes Birth Defects Foundation\uc758 \ud504\ub85c\uadf8\ub7a8 \uae30\ud68d \ubc0f \ucee4\ubba4\ub2c8\ud2f0 \uc11c\ube44\uc2a4 \uad6d\uac00 \uc774\uc0ac, Brown University School of Medicine\uc758 \uc18c\uc544\uacfc \uacb8\uc784 \uc870\uad50\uc218<\/p>\n<p><strong>\ub9ac\ucc28\ub4dc W. \ubca0\uc2a4\ub518, MD, FACP, AGSF<\/strong><br \/>\n\ube0c\ub77c\uc6b4 \ub300\ud559\uad50 \uc758\uacfc\ub300\ud559 \ub178\ub144\ud559 \ubc0f \uac74\uac15 \uad00\ub9ac \uc5f0\uad6c \uc13c\ud130 \uc18c\uc7a5, \uc758\ud559 \uad50\uc218, \ub178\ub144\ud559 \ubd84\uc57c Greer Chair\uc758 \ucd08\ub300 \uc218\uc0c1\uc790, \uc758\ud559\uacfc \ub178\ub144\ud559 \ubd80\ubb38 \ucc45\uc784\uc790<\/p>\n<p><strong>W. \ud14c\ub4dc \ube0c\ub77c\uc6b4, MD, PhD<\/strong><br \/>\n\uc778\uac04 \uc720\uc804\ud559\uacfc \uc758\uc7a5, George A. Jervis Clinic\uc758 \uc774\uc0ac, \ub274\uc695 Staten Island\uc5d0 \uc788\ub294 \ubc1c\ub2ec \uc7a5\uc560\uc5d0 \ub300\ud55c \uae30\ucd08 \uc5f0\uad6c\ub97c \uc704\ud55c \ub274\uc695 \uc8fc\ub9bd \uc5f0\uad6c\uc18c\uc758 \uc784\uc2dc \uc774\uc0ac. \ube0c\ub77c\uc6b4 \ubc15\uc0ac\ub294 Hutchinson-Gilford Progeria \uc99d\ud6c4\uad70\uc758 \uc120\ub3c4\uc801 \uc804\ubb38\uac00\ub85c \uc5ec\uaca8\uc9c4\ub2e4.<\/p>\n<p><strong>\uc608\uce74\ud14c\ub9ac\ub098 F. \ucd94\ub9c8\ucf54\ud504, \ubc15\uc0ac<\/strong><br \/>\nDNA \ubcf5\uc81c, \ubcf5\uad6c \ubc0f \ub3cc\uc5f0\ubcc0\uc774 \uc720\ubc1c \uc139\uc158(SDRRM), \uad6d\ub9bd \uc544\ub3d9 \uac74\uac15 \ubc0f \uc778\uac04 \uac1c\ubc1c \uc5f0\uad6c\uc18c\uc758 \ub0b4\ubd80 \uc5f0\uad6c \ubd80\ubb38, \uc9c1\uc6d0 \uacfc\ud559\uc790<\/p>\n<p><strong>\ud504\ub79c\uc2dc\uc2a4 S. \ucf5c\ub9b0\uc2a4, MD, PhD<\/strong><br \/>\n\uc778\uac04 \uac8c\ub188 \ud504\ub85c\uc81d\ud2b8\ub97c \ub2f4\ub2f9\ud558\ub294 \uad6d\ub9bd\ubcf4\uac74\uc6d0 \uc0b0\ud558 \ubd80\uc11c\uc778 \uad6d\ub9bd\uc778\uac04\uac8c\ub188\uc5f0\uad6c\uc18c \uc18c\uc7a5. \uadf8\uc758 \uc5f0\uad6c\uc2e4\uc740 \ub0ad\ud3ec\uc131 \uc12c\uc720\uc99d, \uc2e0\uacbd\uc12c\uc720\uc885\uc99d, \ud5cc\ud305\ud134\ubcd1\uc744 \ub2f4\ub2f9\ud558\ub294 \uc720\uc804\uc790\ub97c \uc2dd\ubcc4\ud558\ub294 \uc77c\uc744 \ub9e1\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\uc548\ud1a0\ub124\uc774 B. \ucd08\uce74 \ubc15\uc0ac<\/strong><br \/>\n\ub85c\ub4dc\uc544\uc77c\ub79c\ub4dc \uc8fc \ud504\ub85c\ube44\ub358\uc2a4\uc5d0 \uc788\ub294 \ube0c\ub77c\uc6b4 \ub300\ud559\uad50\uc758 \uc874 \uc138\ub514\ube44 \ubc15\uc0ac \uc5f0\uad6c\uc2e4\uc5d0\uc11c HGPS \uc5f0\uad6c\uc5d0\ub9cc \uc804\ub150\ud558\ub294 \ubc15\uc0ac\ud6c4 \uc5f0\uad6c\uc6d0<\/p>\n<div><strong>\ub9c8\ub9ac\uc544 \uc5d0\ub9ad\uc2a8 \ubc15\uc0ac<\/strong><br \/>\n\ucf5c\ub9b0\uc2a4 \ubc15\uc0ac \uc5f0\uad6c\uc2e4\uc758 \ubc15\uc0ac\ud6c4 \uc5f0\uad6c\uc6d0\uc774\uba70, \uadf8\uc758 \ud504\ub85c\uc81d\ud2b8\ub294 \ud5c8\uce5c\uc2a8-\uae38\ud3ec\ub4dc \uc870\ub85c\uc99d \uc99d\ud6c4\uad70\uc744 \ub2e4\ub8e8\ub294 \uac83\uc785\ub2c8\ub2e4.<\/div>\n<p><strong>\uc5d0\ub4dc\uc6cc\ub4dc \ud53c\uc154, MD, PhD<\/strong><br \/>\nMt. Sinai \uc758\ub300 \uc18c\uc544\uacfc \uc0dd\ud654\ud559, \ubd84\uc790\uc0dd\ubb3c\ud559, \uc18c\uc544\uacfc, \uc138\ud3ec\uc0dd\ubb3c\ud559\/\ud574\ubd80\ud559 \uad50\uc218\ub85c, \uc131\uc778\uacfc \uc18c\uc544\uc758 \uc9c0\uc9c8 \uc7a5\uc560\uc5d0 \ub300\ud55c \uc784\uc0c1\uc801 \uad00\uc2ec\uc744 \uac00\uc9c0\uace0 \uc788\uc73c\uba70, \uc804\ubb38 \ubd84\uc57c\ub294 \uc18c\uc544 \uc2ec\uc7a5\ud559\uc785\ub2c8\ub2e4.<\/p>\n<p><strong>\ud1a0\ub9c8\uc2a4 W. \uae00\ub85c\ubc84, \ubc15\uc0ac<\/strong><br \/>\n\ubbf8\uc2dc\uac04 \ub300\ud559(\uc564\uc544\ubc84, \ubbf8\uc2dc\uac04\uc8fc) \uc18c\uc544\uacfc \uad50\uc218\uc774\uc790 \uc778\uac04 \uc720\uc804\ud559 \uad50\uc218\ub85c, \uc5fc\uc0c9\uccb4 \ubd88\uc548\uc815\uc131\uacfc DNA \ubcf5\uad6c\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub97c \uc218\ud589\ud588\uc73c\uba70, \uba58\ucf00\uc2a4 \uc99d\ud6c4\uad70(\uc5d8\ub7ec\uc2a4-\ub304\ub85c\uc2a4 \uc99d\ud6c4\uad70\uc758 \ud754\ud55c \ud615\ud0dc)\uacfc \uc720\uc804\uc131 \ub9bc\ud504\ubd80\uc885\uc744 \ud3ec\ud568\ud55c \ub2e4\uc218\uc758 \uc778\uac04 \uc9c8\ubcd1 \uc720\uc804\uc790\ub97c \uc2dd\ubcc4\ud558\uac70\ub098 \ubcf5\uc81c\ud558\ub294 \ub370 \uc131\uacf5\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<div><strong>\ub9c8\uc774\ud074 W. \uae00\ub9b0<\/strong><br \/>\n\ubbf8\uc2dc\uac04 \ub300\ud559 \uc778\uac04 \uc720\uc804\ud559 \ubc15\uc0ac \ud6c4\ubcf4\uc0dd<\/div>\n<p><strong>\uc2a4\ud2f0\ube10 \uace8\ub4dc\uba3c \ubc15\uc0ac<\/strong><br \/>\n\ubbf8\uad6d \uad6d\ub9bd\ubcf4\uac74\uc6d0(NIH) \uad6d\ub9bd\uc2ec\uc7a5, \ud3d0, \ud608\uc561\uc5f0\uad6c\uc18c, \uc2ec\uc7a5 \ubc0f \ud608\uad00 \uc9c8\ud658\ubd80 \uac74\uac15\uacfc\ud559 \uad00\ub9ac\uc790<\/p>\n<div><strong>\uc624\ub4dc\ub9ac \uace0\ub4e0 \ubcc0\ud638\uc0ac<\/strong><br \/>\n\ud504\ub85c\uac8c\ub9ac\uc544 \uc5f0\uad6c \uc7ac\ub2e8 \ud68c\uc7a5 \uacb8 \uc804\ubb34 \uc774\uc0ac<\/div>\n<p><strong>\ub808\uc2ac\ub9ac \uace0\ub4e0, MD, PhD<\/strong><br \/>\n\ub85c\ub4dc\uc544\uc77c\ub79c\ub4dc \uc8fc \ud504\ub85c\ube44\ub358\uc2a4\uc5d0 \uc788\ub294 Hasbro \uc5b4\ub9b0\uc774 \ubcd1\uc6d0 \uc18c\uc544\uacfc \uac15\uc0ac\uc774\uc790 \ub9e4\uc0ac\ucd94\uc138\uce20 \uc8fc \ubcf4\uc2a4\ud134\uc5d0 \uc788\ub294 Tufts University School of Medicine\uc758 \uc5f0\uad6c\uc6d0\uc73c\ub85c HGPS\uc5d0 \uad00\ud55c \uc5f0\uad6c\ub97c \uc218\ud589\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\ud06c\ub9ac\uc2a4\ud2f4 \ud560\ub9c1-\ubc84\uadf8, \ubc15\uc0ac<\/strong><br \/>\n\ub85c\ub4dc\uc544\uc77c\ub79c\ub4dc\uc8fc \ud504\ub85c\ube44\ub358\uc2a4\uc5d0 \uc788\ub294 \ube0c\ub77c\uc6b4 \ub300\ud559\uad50 \uc758\uacfc\ub300\ud559\uacfc \ub85c\ub4dc\uc544\uc77c\ub79c\ub4dc\uc8fc \ud3ec\ud130\ud0b7\uc5d0 \uc788\ub294 \uba54\ubaa8\ub9ac\uc5bc \ubcd1\uc6d0\uc758 \uc18c\uc544\uacfc \uc870\uad50\uc218\uc774\uc790 \uba74\uc5ed\ud559 \uc870\uad50\uc218<\/p>\n<p><strong>\uc789\uadf8\ub9ac\ub4dc \ud558\ud2bc, MS<\/strong><br \/>\nHGPS\uc640 \uad00\ub828\ub41c \uc8fd\uc0c1\uacbd\ud654\uc99d\uc5d0 \ub300\ud55c \uce58\ub8cc\ubc95\uc744 \uac1c\ubc1c\ud558\uae30 \uc704\ud574 \uc124\uacc4\ub41c \uc77c\ub828\uc758 \uc5f0\uad6c\uc5d0\uc11c \ucd08\uae30 \uc2e4\ud5d8\uc744 \uc218\ud589\ud558\ub294 \uac83\uc73c\ub85c \uad6c\uc131\ub41c Tufts University, \ud574\ubd80\ud559 \ubc0f \uc138\ud3ec\uc0dd\ubb3c\ud559\uacfc\uc758 \uc5f0\uad6c \uc870\uc218<\/p>\n<div><strong>\ub9ac\ucc28\ub4dc J. \ud638\ub370\uc2a4, MD<\/strong><br \/>\n\uad6d\ub9bd\ub178\ud654\uc5f0\uad6c\uc18c \uc18c\uc7a5<\/div>\n<div><strong>\ud5e8\ub9ac\uc5d0\ud0c0 \ud558\uc58f\ud2b8-\ub178\ub974<\/strong><br \/>\n\uad6d\ub9bd\ubcf4\uac74\uc6d0 \ud76c\uadc0\uc9c8\ud658\uad6d \ub300\ud589\uad6d\uc7a5<\/div>\n<p><strong>\ubaa8\ub2c8\uce74 \ud074\ub77c\uc778\ub9cc, MD<\/strong><br \/>\n\ub9e4\uc0ac\ucd94\uc138\uce20\uc8fc \ubcf4\uc2a4\ud134 \uc18c\uc544\ubcd1\uc6d0\uc5d0\uc11c \uc900\uad50\uc218, \uc18c\uc544 \uc911\ud658\uc790 \uce58\ub8cc \ubc0f \uc2e0\uc0dd\uc544\uacfc \uc804\ubb38\uc758, \ub2e4\ud559\uc81c \uc9d1\uc911 \uce58\ub8cc\uc2e4 \ubd80\uc6d0\uc7a5, \uc6b4\uc1a1 \ud504\ub85c\uadf8\ub7a8 \uc758\ub8cc \ucc45\uc784\uc790, \ub9c8\ucde8\uacfc \ubcf4\uc870\uc6d0\uc73c\ub85c \uc77c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\ud3f4 \ub178\ud504 \ubc15\uc0ac<\/strong><br \/>\n\ub85c\ub4dc\uc544\uc77c\ub79c\ub4dc\uc8fc \ud504\ub85c\ube44\ub358\uc2a4\uc5d0 \uc788\ub294 \ube0c\ub77c\uc6b4 \ub300\ud559\uad50 \uba74\uc5ed\ud559 \uad50\uc218, \ube0c\ub77c\uc6b4 \ub300\ud559\uad50 \ubd84\uc790 \ubbf8\uc0dd\ubb3c\ud559 \ubc0f \uba74\uc5ed\ud559\uacfc \uc758\ud559\uacfc Charles A. &amp; Helen B. Stuart \uad50\uc218<\/p>\n<div><strong>\ud558\uc6cc\ub4dc \ud06c\ub8e8\uc2a4, MD<\/strong><br \/>\n\uad6d\ub9bd \uc2ec\uc7a5, \ud3d0, \ud608\uc561 \uc5f0\uad6c\uc18c, \ub0b4\ubd80 \uc5f0\uad6c \ubd80\uc11c, \uc2e4\ud5d8 \ub3d9\ub9e5\uacbd\ud654 \uc139\uc158 \ucc45\uc784\uc790<\/div>\n<p><strong>\uc870\uc548 M. \ub808\ubbf8\uc5b4, \ubc15\uc0ac <\/strong><br \/>\n\ubcf4\uc2a4\ud134\uc758 Tufts University School of Medicine\uc5d0\uc11c \ud574\ubd80\ud559 \ubc0f \uc138\ud3ec\uc0dd\ubb3c\ud559\uacfc\uc758 \uc5f0\uad6c \uc870\uad50\uc218\ub85c, \uc774\uc804 \uc5f0\uad6c\ub294 \uac04\uc554 \ubc1c\uc0dd\uacfc \uc2ec\ud608\uad00 \uc0dd\ubb3c\ud559\uc758 \uc138\ud3ec \uc720\ud615 \ubc0f \uc138\ud3ec\uc678 \ud504\ub85c\ud14c\uc624\uae00\ub9ac\uce78\uc5d0 \uc9d1\uc911\ud588\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \uc5f0\uad6c\ub294 \uc554\uc5d0\uc11c \ud788\uc54c\ub8e8\ub860\uc0b0\uacfc \uc138\ud3ec \ud45c\uba74 \uc218\uc6a9\uccb4\uc778 EMMPRIN\uc758 \uc5ed\ud560\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\uc774\uc0ac\ubca8\ub77c \ub9ac\uc559 \ubc15\uc0ac<\/strong><br \/>\nHSA, \uc2ec\uc7a5 \ubc1c\ub2ec, \uae30\ub2a5 \ubc0f \uae30\ub2a5 \ubd80\uc804 \uc5f0\uad6c \uadf8\ub8f9, \uc2ec\uc7a5 \uc5f0\uad6c \ud504\ub85c\uadf8\ub7a8, \uc2ec\uc7a5 \ubc0f \ud608\uad00 \uc9c8\ud658 \ubd80\uc11c, \uad6d\ub9bd \uc2ec\uc7a5, \ud3d0 \ubc0f \ud608\uc561 \uc5f0\uad6c\uc18c<\/p>\n<p><strong>\ub9c8\uc0ac \ub8ec\ub4dc\ubc84\uadf8 \ubc15\uc0ac<\/strong><br \/>\nHSA, \uc0dd\uccb4\uacf5\ud559 \ubc0f \uac8c\ub188 \uc751\uc6a9 \uc5f0\uad6c \uadf8\ub8f9, \uc784\uc0c1 \ubc0f \ubd84\uc790 \uc758\ud559 \ud504\ub85c\uadf8\ub7a8, \uc2ec\uc7a5 \ubc0f \ud608\uad00 \uc9c8\ud658 \ubd80\uc11c, \uad6d\ub9bd \uc2ec\uc7a5, \ud3d0 \ubc0f \ud608\uc561 \uc5f0\uad6c\uc18c<\/p>\n<p><strong>\uc870\uc9c0 M. \ub9c8\ud2f4, MD<\/strong><br \/>\n\ubcd1\ub9ac\ud559 \uad50\uc218, \uc720\uc804\ud559 \uacb8\uc784 \uad50\uc218, \uc6cc\uc2f1\ud134 \ub300\ud559\uad50 \uc758\uacfc\ub300\ud559 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \uc5f0\uad6c \uc13c\ud130 \uc18c\uc7a5, \uc6cc\uc2f1\ud134 \uc2dc\uc560\ud2c0. \ub9c8\ud2f4 \ubc15\uc0ac\ub294 \ubca0\ub974\ub108 \uc99d\ud6c4\uad70 \uc720\uc804\uc790 \ubc1c\uacac\uc73c\ub85c \uc774\uc5b4\uc9c4 \uc5f0\uad6c \ud504\ub85c\uc81d\ud2b8\ub97c \uc9c0\ud718\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<div><strong>Anna M. McCormick, \ubc15\uc0ac<\/strong><br \/>\n\uad6d\ub9bd\ub178\ud654\uc5f0\uad6c\uc18c \uc0dd\ubb3c\ud559\ubd80\uc7a5, \ub178\ud654\uc0dd\ubb3c\ud559 \ud504\ub85c\uadf8\ub7a8<\/div>\n<div><strong>\uc568\ub7f0 N. \ubaa8\uc178 \ubc15\uc0ac<\/strong><br \/>\n\uad6d\ub9bd \uad00\uc808\uc5fc \ubc0f \uadfc\uace8\uaca9\uacc4 \ubc0f \ud53c\ubd80 \uc9c8\ud658 \uc5f0\uad6c\uc18c \ud53c\ubd80 \uc9c8\ud658 \ubd84\uacfc\uc7a5<\/div>\n<div><strong>\uc624\uc6ec M. \ub808\ub108\ud2b8, MD<\/strong><br \/>\n\uad6d\ub9bd \uc544\ub3d9 \uac74\uac15 \ubc0f \uc778\uac04 \uac1c\ubc1c \uc5f0\uad6c\uc18c, \ub0b4\ubd80 \uc5f0\uad6c \ubd80\ubb38 \uacfc\ud559 \ucc45\uc784\uc790<\/div>\n<p><strong>\ud504\ub7ad\ud06c \ub85c\uc2a4\uba3c \ubc15\uc0ac<\/strong><br \/>\n\ub85c\ub4dc\uc544\uc77c\ub79c\ub4dc \uc8fc \ud504\ub85c\ube44\ub358\uc2a4\uc5d0 \uc788\ub294 \ube0c\ub77c\uc6b4 \ub300\ud559\uad50\uc758 \uc0dd\ubb3c\ud559 \uad50\uc218 \uacb8 \uba85\uc608 \uad50\ubb34\ucc98\uc7a5. 1980\ub144\ub300 \ud6c4\ubc18\uc5d0 \uadf8\ub294 \uc120\ucda9\ub958\uc778 \uc120\ucda9\ub958\uc778 Caenorhabditis elegans\uc758 \ub178\ud654\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub97c \uc218\ud589\ud588\uc2b5\ub2c8\ub2e4. \uba85\uc608\uad50\uc218\ub85c\uc11c \uadf8\ub294 \uc870\ub85c\uc99d\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd98 \ub178\ud654 \uc0dd\ubb3c\ud559\uc5d0 \ub300\ud55c \uacf5\ub3d9 \uc5f0\uad6c\uc5d0 \ucc38\uc5ec\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\uc874 \uc138\ub514\ube44 \ubc15\uc0ac<\/strong><br \/>\n\ube0c\ub77c\uc6b4 \ub300\ud559 \uc720\uc804\ud559 \ubc0f \uc720\uc804\uccb4\ud559 \uc13c\ud130\uc7a5\uc774\uc790 \ube0c\ub77c\uc6b4 \ub300\ud559 \ubd84\uc790\uc0dd\ubb3c\ud559, \uc138\ud3ec\uc0dd\ubb3c\ud559 \ubc0f \uc0dd\ud654\ud559\uacfc\uc758 \uc0dd\ubb3c\ud559 \ubc0f \uc758\ud559 \uad50\uc218\ub85c, \uc720\uc804\ud559\uc744 \uac00\ub974\uce58\uace0 \uc778\uac04 \uc138\ud3ec \ubc0f \uc870\uc9c1\uc758 \ub178\ud654 \uba54\ucee4\ub2c8\uc998\uc744 \uc5f0\uad6c\ud558\ub294 \uc5f0\uad6c \uadf8\ub8f9\uc744 \uc9c0\ub3c4\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\ud504\ub808\ub370\ub9ad \uc0e4\ud53c\ub85c, MD<\/strong><br \/>\n\ubcf4\uc2a4\ud134 \uc18c\uc544\ubcd1\uc6d0 \uc815\ud615\uc678\uacfc \uc870\uad50\uc218\ub85c, \uace8\ub300\uc0ac \ubc0f \uace8\ud615\uc131\ubd80\uc804\uc99d\uacfc \uac19\uc740 \uace8 \uc131\uc7a5 \ubb38\uc81c\ub97c \uc5f0\uad6c\ud569\ub2c8\ub2e4.<\/p>\n<div><strong>\ub9ac\ub178 \ud14c\uc0ac\ub864\ub85c \ubc15\uc0ac<\/strong><br \/>\n\uc2e0\uacbd \ubc1c\ub2ec \uadf8\ub8f9 \ubc0f \uc720\uc804\uc790 \ud0c0\uac9f\ud305 \uc2dc\uc124 \ucc45\uc784\uc790, \ub9c8\uc6b0\uc2a4 \uc554 \uc720\uc804\ud559 \ud504\ub85c\uadf8\ub7a8, \uad6d\ub9bd\uc554\uc5f0\uad6c\uc18c<\/div>\n<p><strong>\ube0c\ub77c\uc774\uc5b8 \ud234 \ubc15\uc0ac<\/strong><br \/>\n\ub9e4\uc0ac\ucd94\uc138\uce20\uc8fc \ubcf4\uc2a4\ud134\uc5d0 \uc788\ub294 Tufts University School of Medicine\uc758 \ud574\ubd80\ud559\uacfc \uad50\uc218, Tufts Health Sciences Campus\uc758 \uc870\uc9c1\ud559 George Bates \uad50\uc218\uc774\uc790 \uc138\ud3ec, \ubd84\uc790 \ubc0f \ubc1c\ub2ec \uc0dd\ubb3c\ud559 \ubc15\uc0ac \uacfc\uc815 \ucc45\uc784\uc790. \uadf8\uc758 \uc5f0\uad6c\uc2e4\uc740 \ud615\ud0dc\ubc1c\uc0dd \ubc0f \uc554\uc5d0\uc11c\uc758 \ud788\uc54c\ub8e8\ub860\uc0b0-\uc138\ud3ec \uc0c1\ud638\uc791\uc6a9\uacfc HGPS\uc5d0 \uc911\uc810\uc744 \ub461\ub2c8\ub2e4.<\/p>\n<p><strong>\ubc84\ub098\ub370\ud2b8 \ud0c0\uc774\ub9ac \ubc15\uc0ac<\/strong><br \/>\n\uac74\uac15 \uacfc\ud559\uc790 \uad00\ub9ac\uc790, \uc5f0\uace8 \ubc0f \uacb0\ud569 \uc870\uc9c1 \ud504\ub85c\uadf8\ub7a8, \ub958\ub9c8\ud2f0\uc2a4 \uc9c8\ud658 \ubd84\uacfc \uad6d\ub9bd \uad00\uc808\uc5fc \ubc0f \uadfc\uace8\uaca9\uacc4 \ubc0f \ud53c\ubd80 \uc9c8\ud658 \uc5f0\uad6c\uc18c<\/p>\n<p><strong>\uc8fc\ub2c8 \uc704\ud1a0, MD, PhD<\/strong><br \/>\n\ud53c\ubd80\uacfc \ubc0f \ud53c\ubd80 \uc0dd\ubb3c\ud559\uacfc\uc758 \uad50\uc218\uc774\uc790 \ud559\uacfc\uc7a5, Jefferson Medical College, Philadelphia, PA\uc758 Jefferson Institute of Molecular Medicine \uc18c\uc7a5. Uitto \ubc15\uc0ac\uc758 \uc5f0\uad6c\ub294 \ud53c\ubd80 \ub178\ud654\uc758 \ubd84\uc790\uc801 \uba54\ucee4\ub2c8\uc998\uc5d0 \ucd08\uc810\uc744 \ub9de\ucda5\ub2c8\ub2e4.<\/p>\n<p><strong>Huber R. Warner, \ubc15\uc0ac<\/strong><br \/>\n\ub178\ud654 \uc0dd\ubb3c\ud559 \ud504\ub85c\uadf8\ub7a8 \ubd80\uc18c\uc7a5, \uad6d\ub9bd \ub178\ud654 \uc5f0\uad6c\uc18c. \uc6cc\ub108 \ubc15\uc0ac\ub294 \uc774 \uc6cc\ud06c\uc20d\uc744 \uc870\uc9c1\ud558\ub294 \ucc45\uc784\uc744 \ub9e1\uc740 NIH \ub300\ud45c\uc774\uba70, \ud504\ub85c\uac8c\ub9ac\uc544 \uc5f0\uad6c \uc7ac\ub2e8\uacfc \ud568\uaed8<\/p>\n<p><strong>\ubab8\ud0c0\uc988 \ubc14\uc138\ud504 \ubc15\uc0ac<\/strong><br \/>\n\ub9ac\ub354, \ub3d9\ub9e5\uacbd\ud654 \uc5f0\uad6c \uadf8\ub8f9, \ud608\uad00\uc0dd\ubb3c\ud559 \uc5f0\uad6c \ud504\ub85c\uadf8\ub7a8, \uc2ec\uc7a5 \ubc0f \ud608\uad00 \uc9c8\ud658 \ubd80\uc11c, \uad6d\ub9bd \uc2ec\uc7a5, \ud3d0 \ubc0f \ud608\uc561 \uc5f0\uad6c\uc18c<\/p>\n<p><strong>\uc564\uc11c\ub2c8 \ubc14\uc774\uc2a4, MD <\/strong><br \/>\n\ud638\uc8fc \uc2dc\ub4dc\ub2c8 \ub300\ud559\uad50 \ubd84\uc790 \ubc0f \uc138\ud3ec \uc0dd\uba85 \uacfc\ud559\ubd80 \ubd84\uc790 \uc0dd\uba85 \uacf5\ud559 \uac00\uc0c1 \ud559\uacfc\uc758 \uc900\uad50\uc218\uc774\uc790 \ubd84\uc790 \uc0dd\uba85 \uacf5\ud559 \ud504\ub85c\uadf8\ub7a8 \ucc45\uc784\uc790. Weiss \ubc15\uc0ac\ub294 \uc9c0\ub09c 12\ub144 \ub3d9\uc548 HGPS\uc5d0\uc11c \uac00\uc7a5 \ub9ce\uc740 \uc218\uc758 \ub3d9\ub8cc \ud3c9\uac00 \uae30\ucd08 \uacfc\ud559 \ub17c\ubb38\uc744 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\ud1a0\ub9c8\uc2a4 \uc640\uc774\ud2b8, \ubc15\uc0ac<\/strong><br \/>\n\ubcd1\ub9ac\ud559 \uad50\uc218, \ud608\uad00 \uc0dd\ubb3c\ud559\uacfc, Hope Heart Institute, Washington Wight \ubc15\uc0ac\ub294 \ud608\uad00 \uc0dd\ubb3c\ud559\uc5d0\uc11c proteoglycans\uacfc hyaluronan\uc758 \uc5ed\ud560\uc5d0 \ub300\ud55c \uc624\ub79c \uad00\uc2ec\uc73c\ub85c \uc774 \uc5f0\uad6c \ubd84\uc57c\uc5d0\uc11c \uc138\uacc4\ub97c \uc120\ub3c4\ud558\ub294 \uc804\ubb38\uac00 \uc911 \ud55c \uba85\uc73c\ub85c \uc790\ub9ac\ub9e4\uae40\ud588\uc2b5\ub2c8\ub2e4. Wight \ubc15\uc0ac\ub294 Arteriosclerosis, Thrombosis and Vascular Biology \uc800\ub110, Journal of Histochemistry &amp; Cytochemistry \uc800\ub110, Glycoconjugate \uc800\ub110, Archives of Biochemistry and Biophysics \uc800\ub110\uc758 \ud3b8\uc9d1 \uc704\uc6d0\ud68c\uc5d0\uc11c \ud65c\ub3d9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p><strong>\uac8c\ub9ac E. \uc640\uc774\uc988, \ubc15\uc0ac<\/strong><br \/>\n\ub8e8\uc774\uc9c0\uc560\ub098 \uc8fc\ub9bd\ub300 \uc218\uc758\uacfc\ub300\ud559 \ube44\uad50\uc0dd\ubb3c\uc758\ud559\uacfc \uad50\uc218 \uacb8 \ud559\uacfc\uc7a5. \uadf8\uc758 \uc5f0\uad6c\uc5d0\ub294 \uce58\uc544 \ubc1c\uce58\uc758 \ubd84\uc790\uc0dd\ubb3c\ud559 \uc5f0\uad6c\uac00 \ud3ec\ud568\ub429\ub2c8\ub2e4.<\/p>\n<p><strong>\ub85c\uc800 \uc6b0\ub4dc\uac8c\uc774\ud2b8 \ubc15\uc0ac<\/strong><br \/>\nDNA \ubcf5\uc81c, \ubcf5\uad6c \ubc0f \ub3cc\uc5f0\ubcc0\uc774 \uc720\ubc1c(SDRRM) \ubd80\ubb38 \ucc45\uc784\uc790, \uad6d\ub9bd \uc544\ub3d9 \uac74\uac15 \ubc0f \uc778\uac04 \uac1c\ubc1c \uc5f0\uad6c\uc18c, \ub0b4\ubd80 \uc5f0\uad6c \ubd80\ubb38<\/p>\n<div><a href=\"https:\/\/www.progeriaresearch.org\/assets\/files\/pdf\/Uitto.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">NIH-PRF \uc6cc\ud06c\uc20d 2001 \u2013 \uc6cc\ud06c\uc20d\uc5d0 \uac8c\uc7ac\ub41c \uae30\uc0ac [53k PDF]<\/a><\/div>\n<p>*\uc591\uc2dd\uc744 \ubcf4\uace0 \uc778\uc1c4\ud558\ub824\uba74 Adobe Acrobat \ud50c\ub7ec\uadf8\uc778\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \ud50c\ub7ec\uadf8\uc778\uc774 \uc5c6\uc73c\uba74 \ubc1b\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. <a href=\"https:\/\/web.archive.org\/web\/20170215225030\/https:\/\/www.adobe.com\/\" target=\"blank\" rel=\"noopener noreferrer\">\uc5ec\uae30<\/a>.<\/p>\n<ul>\n<li><a href=\"https:\/\/www.progeriaresearch.org\/ko\/scientific-meetings\/\">\uc9c0\ub09c \ud68c\uc758<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>NIH-PRF \ud569\ub3d9 \uc6cc\ud06c\uc20d, \ub300\uc131\uacf5! 2001\ub144 11\uc6d4 28-29\uc77c, \uba54\ub9b4\ub79c\ub4dc\uc8fc \ubca0\ub370\uc2a4\ub2e4 \ubbf8\uad6d \uad6d\ub9bd\ubcf4\uac74\uc6d0(NIH) \uc0b0\ud558 \ud504\ub85c\uc81c\ub9ac\uc544 \uc5f0\uad6c\uc7ac\ub2e8(PRF)\uc740 \uacf5\ub3d9\uc73c\ub85c \ud5c8\uce5c\uc2a8-\uae38\ud3ec\ub4dc \ud504\ub85c\uc81c\ub9ac\uc544 \uc99d\ud6c4\uad70\uc5d0 \uad00\ud55c \ucd5c\ucd08\uc758 \uad6d\uc81c \uc6cc\ud06c\uc20d\uc744 2001\ub144 11\uc6d4 28\uc77c\uacfc 29\uc77c \uba54\ub9b4\ub79c\ub4dc\uc8fc \ubca0\ub370\uc2a4\ub2e4\uc5d0\uc11c \uac1c\ucd5c\ud588\uc2b5\ub2c8\ub2e4. 46\uba85\uc758 \uacfc\ud559\uc790\ub4e4\uc774 \uac01 \ubd84\uc57c \uc804\ubb38\uac00\ub4e4\uc758 \ubc1c\ud45c\uc5d0 \uadc0 \uae30\uc6b8\uc600\uc2b5\ub2c8\ub2e4. [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1905","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>2001 workshop | The Progeria Research Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/ko\/2001-first-ever-nih-prf-workshop\/\" \/>\n<meta property=\"og:locale\" content=\"ko_KR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"2001 workshop | The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"Joint Workshop a Resounding Success! NIH-PRF Workshop 2001 Bethesda, MD November 28-29, 2001 The Progeria Research Foundation, jointly with the National Institutes of Health (NIH), held a first-of-its-kind international workshop on Hutchinson-Gilford Progeria Syndrome in Bethesda, Maryland on November 28 and 29, 2001. Forty-six scientists were riveted to the presentations given by leaders from a [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.progeriaresearch.org\/ko\/2001-first-ever-nih-prf-workshop\/\" \/>\n<meta property=\"og:site_name\" content=\"The Progeria Research Foundation\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ProgeriaResearch\/\" \/>\n<meta property=\"article:modified_time\" content=\"2023-09-21T16:37:08+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Progeria\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"11\ubd84\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.progeriaresearch.org\/id\/2001-first-ever-nih-prf-workshop\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/id\/2001-first-ever-nih-prf-workshop\/\",\"name\":\"2001 workshop | The Progeria Research Foundation\",\"isPartOf\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#website\"},\"datePublished\":\"2017-05-09T20:24:40+00:00\",\"dateModified\":\"2023-09-21T16:37:08+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/id\/2001-first-ever-nih-prf-workshop\/#breadcrumb\"},\"inLanguage\":\"ko-KR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.progeriaresearch.org\/id\/2001-first-ever-nih-prf-workshop\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.progeriaresearch.org\/id\/2001-first-ever-nih-prf-workshop\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.progeriaresearch.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"2001, First -ever NIH-PRF Workshop\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#website\",\"url\":\"https:\/\/www.progeriaresearch.org\/ta\/\",\"name\":\"The Progeria Research Foundation\",\"description\":\"For the Children \u2665 For the Cure\",\"publisher\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.progeriaresearch.org\/ta\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ko-KR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\",\"name\":\"The Progeria Research Foundation\",\"url\":\"https:\/\/www.progeriaresearch.org\/ta\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ko-KR\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png\",\"contentUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png\",\"width\":300,\"height\":86,\"caption\":\"The Progeria Research Foundation\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/ProgeriaResearch\/\",\"https:\/\/x.com\/Progeria\",\"https:\/\/www.instagram.com\/progeriaresearch\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"2001\ub144 \uc6cc\ud06c\uc20d | \uc870\ub85c\uc99d \uc5f0\uad6c \uc7ac\ub2e8","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.progeriaresearch.org\/ko\/2001-first-ever-nih-prf-workshop\/","og_locale":"ko_KR","og_type":"article","og_title":"2001 workshop | The Progeria Research Foundation","og_description":"Joint Workshop a Resounding Success! NIH-PRF Workshop 2001 Bethesda, MD November 28-29, 2001 The Progeria Research Foundation, jointly with the National Institutes of Health (NIH), held a first-of-its-kind international workshop on Hutchinson-Gilford Progeria Syndrome in Bethesda, Maryland on November 28 and 29, 2001. 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