{"id":4004,"date":"2018-04-25T00:03:37","date_gmt":"2018-04-25T00:03:37","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?page_id=4004"},"modified":"2023-09-21T12:15:37","modified_gmt":"2023-09-21T16:15:37","slug":"first-ever-demonstrate-survival-benefit-in-progeria","status":"publish","type":"page","link":"https:\/\/www.progeriaresearch.org\/ps\/first-ever-demonstrate-survival-benefit-in-progeria\/","title":{"rendered":"\u067e\u0647 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u06a9\u06d0 \u062f \u0628\u0642\u0627 \u06ab\u067c\u06d0 \u069a\u0648\u062f\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f \u0644\u0648\u0645\u0693\u064a \u0681\u0644 \u0644\u067e\u0627\u0631\u0647 \u062f\u0631\u0645\u0644\u0646\u0647"},"content":{"rendered":"<p>\u062f \u0627\u067e\u0631\u06cc\u0644 24\u060c 2018: \u06cc\u0648\u0647 \u0646\u0648\u06d0 \u0685\u06cc\u0693\u0646\u0647 \u0686\u06d0 \u062f \u0627\u0645\u0631\u06cc\u06a9\u0627\u06cc\u06cc \u0637\u0628\u064a \u0627\u062a\u062d\u0627\u062f\u06cc\u06d0 (JAMA) \u067e\u0647 \u0698\u0648\u0631\u0646\u0627\u0644 \u06a9\u06d0 \u062e\u067e\u0631\u0647 \u0634\u0648\u06d0 \u0631\u0627\u067e\u0648\u0631 \u0648\u0631\u06a9\u0648\u064a \u0686\u06d0 \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628\u060c \u062f \u0641\u0627\u0631\u0646\u0633\u06cc\u0644 \u067c\u0631\u0627\u0646\u0633\u0641\u06cc\u0631\u06cc\u0632 \u0645\u062e\u0646\u06cc\u0648\u06cc (FTI)\u060c \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0631\u0647 \u067e\u0647 \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u06a9\u06d0 \u062f \u0628\u0642\u0627 \u0627\u0648\u0696\u062f\u0648\u0644\u0648 \u06a9\u06d0 \u0645\u0631\u0633\u062a\u0647 \u06a9\u0693\u06d0. \u062f \u0628\u0648\u0633\u067c\u0646 \u062f \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0631\u0648\u063a\u062a\u0648\u0646 \u0627\u0648 \u0628\u0631\u0627\u0648\u0646 \u067e\u0648\u0647\u0646\u062a\u0648\u0646 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\u062f\u0644\u062a\u0647 \u06a9\u0644\u06cc\u06a9 \u0648\u06a9\u0693\u0626<\/b><\/a><\/p>\n<p><strong>\u062f \u0631\u0633\u0646\u06cc\u0648 \u0644\u067e\u0627\u0631\u0647:\u00a0 <\/strong><\/p>\n<ul>\n<li><strong><a href=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2018\/04\/PRF-JAMA-Announcement_Press-Release-1.pdf\">\u0645\u0637\u0628\u0648\u0639\u0627\u062a\u064a \u0627\u0639\u0644\u0627\u0645\u06cc\u0647<\/a><\/strong><\/li>\n<li><strong><a href=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2018\/04\/PRF-JAMA-Announcement-Infographic.pdf\">\u0627\u0646\u0641\u0648\u06ab\u0631\u0627\u0641\u06cc\u06a9<\/a><\/strong><strong>\u00a0<\/strong><\/li>\n<li><a href=\"https:\/\/www.dropbox.com\/sh\/uuq64xv0w0kfrcf\/AAACRWWU4ZKezFTksabaimzba?dl=0\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>\u062f \u0628\u06cc \u0631\u0648\u0644 \u0648\u06cc\u0689\u06cc\u0648<\/strong><\/a><\/li>\n<\/ul>\n<p><strong>\u062f \u067e\u0627\u06cc\u0644\u06d0\u00a0<\/strong><a href=\"https:\/\/www.progeriaresearch.org\/ps\/clinical-trials\/\"><strong>\u062f \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f \u062f\u0631\u0645\u0644\u0648 \u06a9\u0644\u06cc\u0646\u06cc\u06a9\u064a \u0622\u0632\u0645\u0648\u06cc\u0646\u0647<\/strong><\/a><strong>\u00a0\u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0631\u0647 \u0634\u062a\u0648\u0646 \u0644\u0631\u064a \u0627\u0648 \u062f\u0627 \u0631\u0633\u0645\u064a \u062f\u06cc!<\/strong>\u00a0 \u00a0\u0645\u0637\u0627\u0644\u0639\u0647 \u062f \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u067e\u0647 \u06a9\u0627\u0631\u0648\u0644\u0648 \u0633\u0631\u0647 \u060c \u06cc\u0648 \u0689\u0648\u0644 \u0641\u0627\u0631\u0646\u06cc\u0633\u06cc\u0644 \u067c\u0631\u0627\u0646\u0633\u0641\u06cc\u0631\u0633 \u0627\u0646\u0627\u0628\u06cc\u067c\u0631 (FTI) \u067e\u0647 \u0627\u0635\u0644 \u06a9\u06d0 \u062f \u0633\u0631\u0637\u0627\u0646 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\u06a9\u0646\u067c\u0631\u0648\u0644 \u0628\u0631\u062e\u0647 \u06a9\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0631\u0647 \u062f \u0648\u0631\u062a\u0647 \u0639\u0645\u0631\u060c \u062c\u0646\u0633 \u0627\u0648 \u062f \u0627\u0633\u062a\u0648\u06ab\u0646\u06d0 \u0628\u0631\u0627\u0639\u0638\u0645 \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u0646\u0627\u0631\u0648\u063a\u0627\u0646\u0648 \u067e\u0647 \u0685\u06cc\u0631 \u0645\u0627\u0634\u0648\u0645\u0627\u0646 \u0634\u0627\u0645\u0644 \u0648\u0648\u060c \u0686\u06d0 \u062f \u06a9\u0644\u06cc\u0646\u06cc\u06a9\u064a \u0645\u062d\u0627\u06a9\u0645\u06d0 \u0628\u0631\u062e\u0647 \u0646\u0647 \u0648\u0647 \u0627\u0648 \u0644\u0647 \u0647\u0645\u062f\u06d0 \u0627\u0645\u0644\u0647 \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u0646\u0647 \u0648 \u062a\u0631\u0644\u0627\u0633\u0647 \u06a9\u0693\u06cc. \u067e\u0627\u06cc\u0644\u0648 \u069a\u0648\u062f\u0644\u06d0 \u0686\u06d0 \u06cc\u0648\u0627\u0632\u06d0 \u062f \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u062f\u0631\u0645\u0644\u0646\u0647 \u067e\u0631\u062a\u0647 \u0644\u0647 \u06a9\u0648\u0645\u06d0 \u062f\u0631\u0645\u0644\u0646\u06d0 \u0633\u0631\u0647 \u062f 2.2 \u06a9\u0644\u0648\u0646\u0648 \u0645\u062a\u0648\u0633\u0637 \u062a\u0639\u0642\u06cc\u0628 \u0648\u0631\u0648\u0633\u062a\u0647 \u062f \u067e\u0627\u0645 \u0648\u0693 \u067c\u06cc\u067c \u0645\u0693\u06cc\u0646\u06d0 \u06a9\u0686\u0647 (3.7% vs. 33.3%) \u0633\u0631\u0647 \u062a\u0693\u0627\u0648 \u0646\u0644\u0631\u064a. \u062f \u0645\u0637\u0627\u0644\u0639\u06d0 \u067e\u0627\u06cc\u0644\u06d0 \u0686\u06d0 \u0648\u06d0\u00a0<strong>\u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0631\u06cc\u0633\u0631\u0686 \u0641\u0627\u0624\u0646\u0688\u06cc\u0634\u0646 \u0644\u062e\u0648\u0627 \u062a\u0645\u0648\u06cc\u0644 \u0627\u0648 \u0647\u0645\u063a\u0696\u064a \u0634\u0648\u064a<\/strong>\u067e\u0647 24 \u0627\u067e\u0631\u06cc\u0644 2018 \u06a9\u06d0 \u062e\u067e\u0648\u0631 \u0634\u0648 <em>\u062f \u0627\u0645\u0631\u06cc\u06a9\u0627\u06cc\u06cc \u0637\u0628\u064a \u0627\u062a\u062d\u0627\u062f\u06cc\u06d0 \u0698\u0648\u0631\u0646\u0627\u0644.<\/em><\/p>\n<p><em>\u06ab\u0648\u0631\u0689\u0646 \u0627\u06cc\u067c. al.\u060c \u062f \u0644\u0648\u0646\u0627\u0641\u0631\u0646\u06cc\u0628 \u062f\u0631\u0645\u0644\u0646\u06d0 \u067c\u0648\u0644\u0646\u0647 \u067e\u0647 \u0645\u0642\u0627\u0628\u0644 \u06a9\u06d0 \u062f \u0647\u0686\u06cc\u0646\u0633\u0646 - \u06ab\u06cc\u0644\u0641\u0648\u0631\u0689 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0646\u0689\u0631\u0648\u0645 \u0646\u0627\u0631\u0648\u063a\u0627\u0646\u0648 \u06a9\u06d0 \u062f \u0645\u0693\u06cc\u0646\u06d0 \u06a9\u0686\u06d0 \u0633\u0631\u0647 \u0647\u06cc\u0685 \u062f\u0631\u0645\u0644\u0646\u0647<\/em>, <em>JAMA\u060c 24 \u0627\u067e\u0631\u06cc\u0644 2018 319 \u06ab\u06bc\u0647\u060c 16 \u06ab\u06bc\u0647<\/em><strong>\u067e\u0627\u06cc\u0644\u06d0 \u0646\u0648\u06d0 \u0647\u06cc\u0644\u0647 \u0627\u0648 \u062e\u0648\u0634\u0628\u06cc\u0646\u064a \u0631\u0627\u0648\u0693\u064a<br \/>\n<\/strong>\u0645\u0627\u0634\u0648\u0645\u0627\u0646 \u062f \u0647\u0631\u0627\u0693\u062e\u06cc\u0632 \u0637\u0628\u064a \u0627\u0632\u0645\u0648\u06cc\u0646\u06d0 \u0627\u0648 \u0645\u0637\u0627\u0644\u0639\u06d0 \u062f\u0631\u0645\u0644\u0648 \u062a\u0631\u0644\u0627\u0633\u0647 \u06a9\u0648\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f \u0628\u0648\u0633\u067c\u0646 \u062f \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0631\u0648\u063a\u062a\u0648\u0646 \u062a\u0647 \u0633\u0641\u0631 \u0648\u06a9\u0693. \u067c\u0648\u0644\u0648 \u062a\u0631\u0644\u0627\u0633\u0647 \u06a9\u0693\u064a \u0634\u0641\u0627\u0647\u064a \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628\u060c \u06cc\u0648 FTI \u0686\u06d0 \u062f \u0645\u0631\u06a9 \u0627\u0648 \u0634\u0631\u06a9\u062a \u0644\u062e\u0648\u0627 \u0686\u0645\u062a\u0648 \u0634\u0648\u06cc. &quot;\u062f\u0627 \u0685\u06cc\u0693\u0646\u0647 \u0686\u06d0 \u067e\u0647 JAMA \u06a9\u06d0 \u062e\u067e\u0631\u0647 \u0634\u0648\u06d0 \u0634\u0648\u0627\u0647\u062f \u069a\u06cc\u06d0 \u0686\u06d0 \u0645\u0648\u0696 \u06a9\u0648\u0644\u06cc \u0634\u0648 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f \u0639\u0645\u0631 \u06ab\u0693\u0646\u062f\u06cd \u067e\u0631\u0648\u0633\u06d0 \u062a\u0647 \u0648\u0642\u0641\u0647 \u0648\u0631\u06a9\u0693\u0648. \u062f\u0627 \u067e\u0627\u06cc\u0644\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u067c\u0648\u0644\u0646\u06d0 \u062a\u0647 \u0646\u0648\u06d0 \u0698\u0645\u0646\u06d0 \u0627\u0648 \u062e\u0648\u0634\u0628\u06cc\u0646\u064a \u0648\u0693\u0627\u0646\u062f\u06d0 \u06a9\u0648\u064a \u060c &quot;\u0644\u06cc\u0633\u0644\u064a \u06ab\u0648\u0631\u0689\u0646 \u060c MD \u060c PhD \u060c \u062f PRF \u0634\u0631\u06cc\u06a9 \u0628\u0646\u0633\u067c \u0627\u06cc\u069a\u0648\u062f\u0648\u0646\u06a9\u06cc \u0627\u0648 \u0637\u0628\u064a \u0631\u06cc\u06cc\u0633 \u060c \u0627\u0648 \u062f \u0645\u0637\u0627\u0644\u0639\u06d0 \u0645\u062e\u06a9\u069a \u0644\u06cc\u06a9\u0648\u0627\u0644 \u0648\u0648\u06cc\u0644.<\/p>\n<p>&quot;\u067e\u0647 PRF \u06a9\u06d0 \u060c \u0645\u0648\u0696 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0631\u0647 \u0698\u0648\u0646\u062f \u06a9\u0648\u0644\u0648 \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f \u0646\u0648\u064a \u0633\u0627\u06cc\u0646\u0633\u064a \u067e\u0631\u0645\u062e\u062a\u06ab\u0648\u0646\u0648 \u062a\u0645\u0648\u06cc\u0644 \u0644\u067e\u0627\u0631\u0647 \u0646\u0647 \u0633\u062a\u0693\u064a \u06a9\u06cc\u062f\u0648\u0646\u06a9\u064a \u06a9\u0627\u0631 \u06a9\u0648\u0648. \u062f\u0627 \u0685\u06cc\u0693\u0646\u0647 \u0645\u0648\u0696 \u062a\u0647 \u069a\u06cc\u06d0 \u0686\u06d0 \u0646\u0646 \u0648\u0631\u0681 \u062a\u0631\u0633\u0631\u0647 \u0634\u0648\u064a \u06a9\u0644\u06cc\u0646\u06cc\u06a9\u064a \u0622\u0632\u0645\u0648\u06cc\u0646\u06d0 \u067e\u0647 \u0631\u0627\u062a\u0644\u0648\u0646\u06a9\u064a \u06a9\u06d0 \u062f \u062f\u06d0 \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f \u0698\u063a\u0648\u0631\u0646\u06d0 \u0644\u067e\u0627\u0631\u0647 \u0632\u0645\u0648\u0696 \u063a\u0648\u0631\u0647 \u0647\u06cc\u0644\u0647 \u062f\u0647. \u062f \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u0633\u0631\u0647 \u062f \u062f\u06d0 \u0645\u0637\u0627\u0644\u0639\u06d0 \u062f \u0627\u0645\u06cc\u062f \u0648\u0693 \u067e\u0627\u06cc\u0644\u0648 \u067e\u0631\u0627\u0633\u0627\u0633\u060c \u0645\u0648\u0696 \u062f \u0628\u0644 \u0647\u0631 \u0648\u062e\u062a \u067e\u0647 \u067e\u0631\u062a\u0644\u0647 \u062f \u0628\u06cc\u0693\u0646\u064a \u0627\u062d\u0633\u0627\u0633 \u0627\u062d\u0633\u0627\u0633 \u06a9\u0648\u0648. \u062f \u0646\u0646 \u0648\u0631\u0681\u06d0 \u067e\u0693\u0627\u0648 \u062f \u062f\u063a\u0648 \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0627\u0648 \u062f \u0647\u063a\u0648\u06cc \u062f \u06a9\u0648\u0631\u0646\u06cc\u0648 \u0644\u067e\u0627\u0631\u0647 \u06cc\u0648 \u0646\u0648\u06cc \u067e\u06cc\u0644 \u062f\u06cc. \u0647\u0631\u0647 \u0648\u0631\u0681 \u0627\u0648 \u0647\u0631\u0647 \u0634\u06cc\u0628\u0647 \u062d\u0633\u0627\u0628\u06cc\u0696\u064a. \u062f PRF \u0647\u062f\u0641 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0644\u067e\u0627\u0631\u0647 \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u0645\u0648\u0646\u062f\u0644 \u062f\u064a \u0627\u0648 \u062f\u0627 \u0645\u0637\u0627\u0644\u0639\u0647 \u0645\u0648\u0696 \u062a\u0647 \u062f \u062f\u06d0 \u0647\u062f\u0641 \u067e\u0647 \u0644\u0648\u0631 \u06cc\u0648 \u0628\u0644 \u06ab\u0627\u0645 \u0631\u0627\u0648\u0693\u064a \u060c &quot;\u0645\u06cc\u0631\u06cc\u0644 \u0641\u0646\u06a9 \u0648\u0648\u06cc\u0644 \u060c \u062f PRF \u0648\u0644\u0633\u0645\u0634\u0631 \u0627\u0648 \u0627\u062c\u0631\u0627\u06cc\u0648\u064a \u0631\u06cc\u06cc\u0633.<\/p>\n<p><strong>\u062f \u0631\u0633\u0646\u06cc\u0648 \u067e\u0648\u069a\u069a<\/strong><\/p>\n<p>\u062f\u0644\u062a\u0647 \u062f \u062a\u0631\u0644\u0627\u0633\u0647 \u0634\u0648\u064a \u0645\u0637\u0628\u0648\u0639\u0627\u062a\u064a \u067e\u0648\u069a\u069a \u06cc\u0648\u0647 \u0646\u0645\u0648\u0646\u0647 \u062f\u0647:<\/p>\n<ul>\n<li><strong>MedPage \u0646\u0646 \u0648\u0631\u0681<br \/>\n<\/strong><a href=\"https:\/\/www.medpagetoday.com\/blogs\/themethodsman\/72505\" target=\"_blank\" rel=\"noopener noreferrer\"><em>\u062f\u0631\u0645\u0644 \u06a9\u0648\u0644\u06cc \u0634\u064a \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0627\u062f\u0627\u0631\u0647 \u06a9\u0693\u064a <\/em><\/a><\/li>\n<li><strong>\u062f \u0628\u0648\u0633\u067c\u0646 \u06ab\u0644\u0648\u0628<\/strong><br \/>\n<a href=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2018\/07\/The-Boston-Globe_A-pediatric-researcher-whose-son-died-of-progeria-sees-....pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><em>\u062f \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u062f \u0646\u0627\u0631\u0648\u063a\u06cd \u0685\u06cc\u0693\u0648\u0646\u06a9\u06cc \u0686\u06d0 \u0632\u0648\u06cc \u06cc\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0644\u0647 \u0627\u0645\u0644\u0647 \u0645\u0693 \u0634\u0648\u06cc \u062f \u0646\u0648\u064a \u062f\u0631\u0645\u0644\u0646\u06d0 \u0698\u0645\u0646\u06d0 \u06ab\u0648\u0631\u064a<\/em> \u0627\u067e\u0631\u06cc\u0644 24\u060c 2018<\/a><\/li>\n<li><strong>\u0628\u0631\u0627\u0648\u0646 \u062e\u0628\u0631\u0648\u0646\u0647<\/strong><br \/>\n<a href=\"https:\/\/news.brown.edu\/articles\/2018\/04\/progeria\" target=\"_blank\" rel=\"noopener noreferrer\"><em>\u0685\u06cc\u0693\u0646\u06d0 \u0648\u0693\u0627\u0646\u062f\u06cc\u0632 \u06a9\u0648\u064a \u0686\u06d0 \u062f \u0648\u062e\u062a \u062f\u0645\u062e\u0647 \u0639\u0645\u0631 \u0644\u0631\u0648\u0646\u06a9\u064a \u0646\u0627\u0631\u0648\u063a\u06cd \u0644\u067e\u0627\u0631\u0647 \u062f \u062f\u0631\u0645\u0644\u0648 \u062f\u0631\u0645\u0644\u0646\u0647 \u0698\u0645\u0646\u0647 \u06a9\u0648\u064a<\/em> \u0627\u067e\u0631\u06cc\u0644 24\u060c 2018<\/a><\/li>\n<\/ul>\n<p><em>&quot;\u062f\u0627 \u06cc\u0648\u0647 \u06a9\u06cc\u0633\u0647 \u062f\u0647 \u0686\u06d0 \u067e\u0647 \u0689\u06cc\u0631\u06cc \u06a9\u0686\u0648 \u06a9\u06d0 \u0627\u0644\u0647\u0627\u0645 \u0628\u062e\u069a\u0648\u0646\u06a9\u06d0 \u062f\u0647. \u062f \u062e\u0648\u0631\u0627 \u0681\u0627\u0646\u06ab\u0693\u064a \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u062f \u06cc\u0648\u06d0 \u0689\u0644\u06d0 \u0698\u0648\u0646\u062f \u0628\u062f\u0644\u0648\u0644\u0648 \u0648\u0693\u062a\u06cc\u0627 \u0634\u062a\u0648\u0646 \u0644\u0631\u064a. \u0645\u06ab\u0631 \u062f\u0627 \u062f \u0633\u0627\u06cc\u0646\u0633\u064a \u0645\u06cc\u062a\u0648\u062f \u0645\u062b\u0627\u0644 \u0647\u0645 \u062f\u06cc \u0686\u06d0 \u0633\u0645 \u067e\u0631\u0645\u062e \u062a\u0644\u0644\u064a \u060c \u0686\u06cc\u0631\u06d0 \u0686\u06d0 \u0633\u062e\u062a \u0644\u0648\u0645\u0693\u0646\u064a \u0633\u0627\u06cc\u0646\u0633 \u0627\u0648 \u062f \u0645\u0648\u062c\u0648\u062f\u0647 \u062f\u0631\u0645\u0644\u0648 \u0633\u0645\u0627\u0631\u067c \u063a\u0648\u069a\u062a\u0646\u0644\u06cc\u06a9 \u06ab\u0689\u06d0 \u067e\u0627\u06cc\u0644\u06d0 \u0631\u0627\u0645\u06cc\u0646\u0681\u062a\u0647 \u06a9\u0648\u064a \u0686\u06d0 \u0631\u06cc\u069a\u062a\u06cc\u0646\u064a \u0628\u0631\u06cc\u0627\u0648\u06d0 \u062f\u064a.<\/em><\/p>\n<p><em>\u2013 F. Perry Wilson MD, MSCE, \u062f \u06cc\u06cc\u0644 \u062f \u0637\u0628 \u069a\u0648\u0648\u0646\u0681\u06cc, \u0645\u06cc\u0689 \u067e\u06cc\u062c \u0646\u0646 \u0648\u0631\u0681<\/em><\/p>\n<p><strong>\u0645\u0648\u0696 \u0685\u0646\u06ab\u0647 \u062f\u06d0 \u067e\u0647 \u0632\u0693\u0647 \u067e\u0648\u0631\u06d0 \u0648\u0631\u0681 \u062a\u0647 \u0648\u0631\u0633\u06cc\u062f\u0648\u061f<\/strong><br \/>\n\u067e\u0647 \u062a\u0639\u0642\u06cc\u0628 <a href=\"https:\/\/www.progeriaresearch.org\/ps\/identification-of-gene-gives-hope-to-children-with-progeria\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u067e\u0647 2003 \u06a9\u06d0 \u062f \u062c\u06cc\u0646 \u0628\u062f\u0644\u0648\u0646 \u06a9\u0634\u0641<\/a> \u0686\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0644\u0627\u0645\u0644 \u06a9\u06cc\u0696\u064a \u060c \u062f PRF \u0644\u062e\u0648\u0627 \u062a\u0645\u0648\u06cc\u0644 \u0634\u0648\u064a \u0685\u06cc\u0693\u0648\u0646\u06a9\u064a \u067e\u06cc\u0698\u0646\u062f\u0644 \u0634\u0648\u064a\u00a0<a href=\"https:\/\/www.progeriaresearch.org\/ps\/the-fti-drug\/\">FTIs<\/a>\u00a0\u062f \u0627\u062d\u062a\u0645\u0627\u0644\u064a \u062f\u0631\u0645\u0644\u0648 \u062f\u0631\u0645\u0644\u0646\u06d0 \u067e\u0647 \u062a\u0648\u06ab\u0647. \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0644\u0627\u0645\u0644 \u0634\u0648\u06cc \u062a\u063a\u06cc\u0631 \u062f \u067e\u0631\u0648\u067c\u06cc\u0646 \u062a\u0648\u0644\u06cc\u062f \u0644\u0627\u0645\u0644 \u06a9\u06cc\u0696\u064a\u00a0<em>progerin<\/em>\u060c \u06a9\u0648\u0645 \u0686\u06d0 \u062f \u062d\u062c\u0631\u0648 \u0641\u0639\u0627\u0644\u06cc\u062a \u062a\u0647 \u0632\u06cc\u0627\u0646 \u0631\u0633\u0648\u064a. \u067e\u0647 \u0628\u062f\u0646 \u0628\u0627\u0646\u062f\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0632\u0647\u0631\u062c\u0646 \u062a\u0627\u062b\u06cc\u0631 \u06cc\u0648\u0647 \u0628\u0631\u062e\u0647 \u062f \u0645\u0627\u0644\u06cc\u06a9\u0648\u0644 \u0644\u0647 \u0627\u0645\u0644\u0647 \u0631\u0627\u0645\u06cc\u0646\u0681\u062a\u0647 \u06a9\u06cc\u0696\u064a \u0686\u06d0 \u062f &quot;\u0641\u0627\u0631\u0646\u06cc\u0633\u06cc\u0644 \u06ab\u0631\u0648\u067e&quot; \u067e\u0647 \u0646\u0648\u0645 \u06cc\u0627\u062f\u06cc\u0696\u064a \u060c \u06a9\u0648\u0645 \u0686\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u067e\u0631\u0648\u067c\u06cc\u0646 \u0633\u0631\u0647 \u0646\u069a\u0644\u0648\u064a \u0627\u0648 \u062f \u0628\u062f\u0646 \u062d\u062c\u0631\u0648 \u062a\u0647 \u0632\u06cc\u0627\u0646 \u0631\u0633\u0648\u0644\u0648 \u06a9\u06d0 \u0645\u0631\u0633\u062a\u0647 \u06a9\u0648\u064a. FTIs \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0633\u0631\u0647 \u062f \u0641\u0627\u0631\u0646\u06cc\u0633\u06cc\u0644 \u06ab\u0631\u0648\u067e \u0636\u0645\u06cc\u0645\u0647 \u0628\u0646\u062f\u0648\u0644\u0648 \u0633\u0631\u0647 \u0639\u0645\u0644 \u06a9\u0648\u064a \u060c \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0632\u06cc\u0627\u0646 \u0644\u0627\u0645\u0644\u0648\u0646\u0647 \u06a9\u0645\u0648\u064a.<\/p>\n<p><strong>\u062f \u0645\u0637\u0627\u0644\u0639\u06d0 \u062f \u0646\u0648\u0631\u0648 \u062c\u0632\u06cc\u0627\u062a\u0648 \u0644\u067e\u0627\u0631\u0647\u060c\u00a0<a href=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2018\/04\/PRF-JAMA-Announcement_Press-Release-1.pdf\">\u062f \u0645\u0637\u0628\u0648\u0639\u0627\u062a\u064a \u0627\u0639\u0644\u0627\u0645\u06cc\u06d0 \u0644\u067e\u0627\u0631\u0647 \u062f\u0644\u062a\u0647 \u06a9\u0644\u06cc\u06a9 \u0648\u06a9\u0693\u0626<\/a> <\/strong><\/p>\n<p><em>&quot;\u062f \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u067e\u0647 \u062f\u06d0 \u06a9\u0648\u0686\u0646\u064a \u0646\u0641\u0648\u0633 \u06a9\u06d0 \u062f \u062f\u06d0 \u0646\u0627\u062f\u0631 \u0648\u0698\u0648\u0646\u06a9\u064a \u0646\u0627\u0631\u0648\u063a\u06cd \u0633\u0631\u0647 \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u0627\u063a\u06cc\u0632\u0645\u0646\u062a\u0648\u0628 \u069a\u0648\u062f\u0644 \u06cc\u0648\u0647 \u0644\u0648\u06cc\u0647 \u0646\u0646\u06ab\u0648\u0646\u0647 \u062f\u0647. \u067e\u0647 \u062f\u06d0 \u062a\u0648\u06ab\u0647\u060c \u0632\u0647 \u067e\u0647 \u0681\u0627\u0646\u06ab\u0693\u06d0 \u062a\u0648\u06ab\u0647 \u062f \u062f\u06d0 \u0648\u0631\u0648\u0633\u062a\u06cc\u0648 \u0645\u0648\u0646\u062f\u0646\u0648 \u0644\u062e\u0648\u0627 \u0647\u0685\u0648\u0644 \u0634\u0648\u06cc \u06cc\u0645.<\/em><\/p>\n<p><em>- \u0689\u0627\u06a9\u067c\u0631 \u0641\u0631\u0627\u0646\u0633\u06cc\u0633 \u06a9\u0648\u0644\u06cc\u0646\u0632\u060c \u062f \u0631\u0648\u063a\u062a\u06cc\u0627 \u0645\u0644\u064a \u0627\u0646\u0633\u067c\u06cc\u067c\u06cc\u0648\u067c \u0631\u06cc\u06cc\u0633<\/em><\/p>\n<p><strong>\u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u062f \u0639\u0645\u0631 \u0646\u0648\u0631\u0645\u0627\u0644 \u067e\u0631\u0648\u0633\u06d0 \u0633\u0631\u0647 \u062a\u0693\u0627\u0648 \u0644\u0631\u064a<\/strong><a href=\"https:\/\/web-beta.archive.org\/web\/20170128050324\/https:\/www.progeriaresearch.org\/whats_new_in_progeria_research.html#2\"><br \/>\n<\/a>\u0685\u06cc\u0693\u0646\u06d0 \u069a\u06cc\u06d0 \u0686\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0644\u0627\u0645\u0644 \u06a9\u06cc\u0696\u064a \u067e\u0631\u0648\u067c\u06cc\u0646\u00a0<em>progerin<\/em>\u00a0\u067e\u0647 \u0639\u0627\u0645\u0648 \u062e\u0644\u06a9\u0648 \u06a9\u06d0 \u0647\u0645 \u067e\u06cc\u062f\u0627 \u06a9\u06cc\u0696\u064a \u0627\u0648 \u062f \u0639\u0645\u0631 \u0633\u0631\u0647 \u0632\u06cc\u0627\u062a\u06cc\u0696\u064a. \u0685\u06cc\u0693\u0648\u0646\u06a9\u064a \u067e\u0644\u0627\u0646 \u0644\u0631\u064a \u0686\u06d0 \u062f FTIs \u0627\u063a\u06cc\u0632\u06d0 \u0633\u067e\u0693\u0644\u0648 \u062a\u0647 \u062f\u0648\u0627\u0645 \u0648\u0631\u06a9\u0693\u064a\u060c \u06a9\u0648\u0645 \u0686\u06d0 \u06a9\u06cc\u062f\u0627\u06cc \u0634\u064a \u0633\u0627\u06cc\u0646\u0633 \u067e\u0648\u0647\u0627\u0646\u0648 \u0633\u0631\u0647 \u062f \u0632\u0693\u0647 \u062f \u0646\u0627\u0631\u0648\u063a\u06cd \u067e\u0647 \u0627\u0693\u0647 \u0646\u0648\u0631 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0632\u062f\u0647 \u06a9\u0693\u064a \u0686\u06d0 \u067e\u0647 \u0645\u06cc\u0644\u06cc\u0648\u0646\u0648\u0646\u0648 \u0627\u063a\u06cc\u0632\u0647 \u06a9\u0648\u064a\u060c \u0627\u0648 \u0647\u0645\u062f\u0627\u0631\u0646\u06ab\u0647 \u062f \u0639\u0645\u0631 \u0646\u0648\u0631\u0645\u0627\u0644 \u0628\u0647\u06cc\u0631 \u0686\u06d0 \u0645\u0648\u0696 \u067c\u0648\u0644 \u0627\u063a\u06cc\u0632\u0645\u0646 \u06a9\u0648\u064a.<\/p>\n<p><strong>\u0644\u0647 \u067c\u0648\u0644\u0648 \u0645\u0646\u0646\u0647 \u2013<\/strong>\u00a0<strong>\u0645\u0648\u0696 \u062f\u0627 \u0644\u0647 \u062a\u0627\u0633\u0648 \u067e\u0631\u062a\u0647 \u0646\u0647 \u0634\u0648 \u06a9\u0648\u0644\u06cc!<\/strong><br \/>\n\u06cc\u0648 \u0644\u0647 \u0627\u0635\u0644\u064a \u062f\u0644\u06cc\u0644\u0648\u0646\u0648 \u0685\u062e\u0647 \u0686\u06d0 \u0645\u0648\u0696 \u062f \u062f\u06d0 \u0628\u0631\u06cc\u0627 \u067e\u0627\u06cc\u0644\u06d0 \u062a\u0631\u0644\u0627\u0633\u0647 \u06a9\u0693\u06d0 \u062f \u062e\u0648\u0631\u0627 \u0644\u0648\u06cc \u0645\u0644\u0627\u062a\u0693 \u06a9\u0648\u0646\u06a9\u0648 \u0644\u0647 \u0627\u0645\u0644\u0647 \u062f\u064a \u0686\u06d0 \u062a\u0645\u0648\u06cc\u0644 \u0627\u0648 \u0646\u0648\u0631 \u0645\u0644\u0627\u062a\u0693 \u06cc\u06d0 \u0686\u0645\u062a\u0648 \u06a9\u0693\u06cc \u060c \u0632\u0645\u0648\u0696 \u062f \u0648\u0631\u0648\u0633\u062a\u064a \u0647\u062f\u0641 \u062a\u0631\u0644\u0627\u0633\u0647 \u06a9\u0648\u0644\u0648 \u062a\u0647 \u06cc\u0648 \u06ab\u0627\u0645 \u0646\u0696\u062f\u06d0 \u06a9\u06cc\u062f\u0648 \u06a9\u06d0 \u0645\u0631\u0633\u062a\u0647 \u06a9\u0648\u064a - \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u062f\u0631\u0645\u0644\u0646\u0647.<\/p>","protected":false},"excerpt":{"rendered":"<p>April 24, 2018: A new study published in The Journal of the American Medical Association (JAMA) reports that lonafarnib, a farnesyltransferase inhibitor (FTI), helped extend survival in children with Progeria. Authors from Boston Children\u2019s Hospital and Brown University tracked more than 250 children from six continents to demonstrate a link between lonafarnib treatment and extended [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-4004","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>First Ever | The Progeria Research Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/ps\/first-ever-demonstrate-survival-benefit-in-progeria\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"First Ever | The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"April 24, 2018: A new study published in The Journal of the American Medical Association (JAMA) reports that lonafarnib, a farnesyltransferase inhibitor (FTI), helped extend survival in children with Progeria. 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