{"id":12401,"date":"2021-03-11T21:08:40","date_gmt":"2021-03-12T02:08:40","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=12401"},"modified":"2022-11-14T17:12:14","modified_gmt":"2022-11-14T22:12:14","slug":"exciting-breakthroughs-in-rna-therapeutics-for-progeria","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/ps\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/","title":{"rendered":"\u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0644\u067e\u0627\u0631\u0647 \u062f RNA \u062f\u0631\u0645\u0644\u0646\u06d0 \u06a9\u06d0 \u067e\u0647 \u0632\u0693\u0647 \u067e\u0648\u0631\u064a \u0628\u0631\u06cc\u0627\u0648\u06d0!"},"content":{"rendered":"

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\u062f \u0628\u0644\u0647 \u0645\u0637\u0627\u0644\u0639\u0647<\/a>\u062f \u067c\u0627\u0645 \u0645\u06cc\u0633\u062a\u06cc\u0644\u064a \u067e\u0647 \u0645\u0634\u0631\u06cd\u060c \u067e\u06cc \u0627\u06cc\u0686 \u0689\u06cc\u060c \u062f \u0633\u0631\u0637\u0627\u0646 \u062f \u0685\u06cc\u0693\u0646\u06d0 \u0645\u0631\u06a9\u0632 \u0631\u06cc\u06cc\u0633\u060c \u062f \u0645\u0644\u064a \u0633\u0631\u0637\u0627\u0646 \u0627\u0646\u0633\u067c\u06cc\u067c\u06cc\u0648\u067c\u060c NIH\u060c \u069a\u0648\u062f\u0644\u06d0. 90 - 95% \u062f \u0632\u0647\u0631\u062c\u0646 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u062a\u0648\u0644\u06cc\u062f\u0648\u0646\u06a9\u064a RNA \u06a9\u0645\u0648\u0644<\/strong> \u062f LB143 \u067e\u0647 \u0646\u0648\u0645 \u062f \u062f\u0631\u0645\u0644\u0648 \u0633\u0631\u0647 \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u0648\u0631\u0648\u0633\u062a\u0647 \u067e\u0647 \u0645\u062e\u062a\u0644\u0641 \u0646\u0633\u062c\u0648\u0646\u0648 \u06a9\u06d0. \u062f \u0645\u0633\u067c\u0644\u064a \u0644\u0627\u0628\u0631\u0627\u062a\u0648\u0627\u0631 \u0648\u0645\u0648\u0646\u062f\u0644\u0647 \u0686\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u067e\u0631\u0648\u067c\u06cc\u0646 \u06a9\u0645\u069a\u062a \u067e\u0647 \u0681\u06cc\u06ab\u0631 \u06a9\u06d0 \u062e\u0648\u0631\u0627 \u0645\u0624\u062b\u0631\u0647 \u0648 \u060c \u067e\u0647 \u0632\u0693\u0647 \u0627\u0648 \u0627\u0648\u0631\u067c\u0627 \u06a9\u06d0 \u062f \u0627\u0636\u0627\u0641\u064a \u067e\u0631\u0645\u062e\u062a\u06ab\u0648\u0646\u0648 \u0633\u0631\u0647.<\/p>\n

\u0645\u0648\u0696 \u0627\u0648\u0633 \u067e\u0648\u0647\u06cc\u0696\u0648 \u0686\u06d0 \u062f RNA \u062f\u0631\u0645\u0644\u0646\u06d0 \u067e\u0647 \u06a9\u0627\u0631\u0648\u0644\u0648 \u0633\u0631\u0647 \u062f \u0632\u06cc\u0627\u0646 \u0631\u0633\u0648\u0646\u06a9\u064a \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u067e\u0631\u0648\u067c\u06cc\u0646 \u062a\u0648\u0644\u06cc\u062f \u06a9\u0645\u0648\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u0689\u06cc\u0631\u06cc \u0644\u0627\u0631\u06d0 \u0634\u062a\u0648\u0646 \u0644\u0631\u064a. \u0647\u0631\u06d0 \u0685\u06cc\u0693\u0646\u06d0 \u062f \u0645\u0648\u0696\u06a9 \u067e\u0647 \u0645\u0627\u0689\u0644\u0648\u0646\u0648 \u06a9\u06d0 \u062f RNA \u0645\u062e\u062a\u0644\u0641\u06d0 \u0628\u0631\u062e\u06d0 \u0648\u0645\u0648\u0646\u062f\u0644\u06d0 \u0686\u06d0 \u06a9\u0644\u0647 \u067e\u0647 \u0646\u069a\u0647 \u0634\u064a\u060c \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u0644\u067e\u0627\u0631\u0647 \u0627\u063a\u06cc\u0632\u0645\u0646\u0647 \u0644\u0627\u0631\u0647 \u0648\u0693\u0627\u0646\u062f\u06d0 \u06a9\u0693\u064a\u060c \u067e\u0647 \u067e\u0627\u06cc\u0644\u0647 \u06a9\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0645\u0648\u0696\u06a9 \u0686\u06d0 \u062f \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u0633\u0631\u0647 \u067e\u0647 \u062a\u06cc\u0631\u0648 \u0645\u0637\u0627\u0644\u0639\u0627\u062a\u0648 \u06a9\u06d0 \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u067e\u0647 \u067e\u0631\u062a\u0644\u0647 \u0689\u06cc\u0631 \u0627\u0648\u0696\u062f \u0698\u0648\u0646\u062f \u06a9\u0648\u064a<\/strong>\u060c \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0631\u0647 \u062f \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0644\u067e\u0627\u0631\u0647 \u06cc\u0648\u0627\u0632\u06cc\u0646\u06cc \u062f FDA \u0644\u062e\u0648\u0627 \u062a\u0635\u0648\u06cc\u0628 \u0634\u0648\u06cc \u062f\u0631\u0645\u0644. \u0633\u0631\u0628\u06cc\u0631\u0647 \u067e\u0631\u062f\u06d0\u060c \u0685\u06cc\u0693\u0648\u0646\u06a9\u0648 \u0648\u0645\u0648\u0646\u062f\u0644\u0647 \u0686\u06d0 \u062f RNA \u062f\u0631\u0645\u0644\u0646\u06d0 \u0627\u0648 \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u0633\u0631\u0647 \u062a\u0631\u06a9\u06cc\u0628 \u062f\u0631\u0645\u0644\u0646\u0647 \u067e\u0647 \u0681\u06cc\u06ab\u0631 \u0627\u0648 \u0632\u0693\u0647 \u06a9\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u067e\u0631\u0648\u067c\u06cc\u0646 \u06a9\u0686\u0647 \u067e\u0647 \u062e\u067e\u0644\u0647 \u062f \u06cc\u0648\u06d0 \u062f\u0631\u0645\u0644\u0646\u06d0 \u067e\u0647 \u067e\u0631\u062a\u0644\u0647 \u062e\u0648\u0631\u0627 \u0645\u0624\u062b\u0631\u0647 \u06a9\u0645\u0647 \u06a9\u0693\u06d0.<\/p>\n

"\u062f\u0627 \u062f\u0648\u0647 \u062e\u0648\u0631\u0627 \u0645\u0647\u0645\u06d0 \u0685\u06cc\u0693\u0646\u06d0 \u069a\u06cc\u064a \u0644\u0648\u06cc \u067e\u0631\u0645\u062e\u062a\u06ab\u0648\u0646\u0647 \u0686\u06d0 \u0627\u0648\u0633 \u0632\u0645\u0648\u0696 \u067e\u0647 \u0644\u0627\u0633 \u06a9\u06d0 \u062f\u064a<\/strong> \u062f \u0646\u069a\u0647 \u0634\u0648\u064a \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u062f\u0631\u0645\u0644\u0646\u06d0 \u067e\u0647 \u0628\u0631\u062e\u0647 \u06a9\u06d0 \u060c "\u062f PRF \u0637\u0628\u064a \u0631\u06cc\u06cc\u0633 \u0689\u0627\u06a9\u067c\u0631 \u0644\u06cc\u0633\u0644\u064a \u06ab\u0648\u0631\u0689\u0646 \u0648\u0648\u06cc\u0644. "\u0632\u0647 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0631\u0647 \u062f \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f RNA \u062f\u0631\u0645\u0644\u0646\u06d0 \u062a\u0647 \u0648\u062f\u0647 \u0648\u0631\u06a9\u0648\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f \u062f\u06d0 \u0639\u0627\u0644\u064a \u0685\u06cc\u0693\u0646\u06cc\u0632\u0648 \u0689\u0644\u0648 \u0633\u0631\u0647 \u06a9\u0627\u0631 \u06a9\u0648\u0644\u0648 \u0685\u062e\u0647 \u062e\u0648\u069a \u0648\u0645. \u062f\u0648\u0627\u0693\u0647 \u062f \u0627\u0635\u0648\u0644\u0648 \u0645\u0637\u0627\u0644\u0639\u06d0 \u067e\u0647 \u0632\u0693\u0647 \u067e\u0648\u0631\u06d0 \u062b\u0628\u0648\u062a \u062f\u064a\u060c \u0627\u0648 PRF \u0644\u06cc\u0648\u0627\u0644\u0647 \u062f\u06cc \u0686\u06d0 \u062f \u06a9\u0644\u06cc\u0646\u06cc\u06a9\u064a \u0622\u0632\u0645\u0648\u06cc\u0646\u0648 \u067e\u0647 \u0644\u0648\u0631 \u0645\u062e \u067e\u0647 \u0648\u0693\u0627\u0646\u062f\u06d0 \u0644\u0627\u0693 \u0634\u064a<\/strong> \u0686\u06d0 \u062f\u0627 \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u0633\u062a\u0631\u0627\u062a\u06cc\u0698\u06cd \u067e\u0644\u064a \u06a9\u0648\u064a.<\/p>\n

 <\/p>\n

-<\/p>\n

Erdos, MR, Cabral, WA, Tavarez, UL\u00a0et al.<\/i>\u00a0\u062f \u0647\u0686\u06cc\u0646\u0633\u0646 \u2013 \u06ab\u06cc\u0644\u0641\u0648\u0631\u0689 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0646\u0689\u0631\u0648\u0645 \u0644\u067e\u0627\u0631\u0647 \u067e\u0647 \u0646\u069a\u0647 \u0634\u0648\u064a \u0627\u0646\u067c\u064a \u0633\u06cc\u0646\u0633 \u0645\u0639\u0627\u0644\u062c\u0648\u064a \u0686\u0644\u0646\u062f.\u00a0\u0646\u06cc\u067c \u0645\u06cc\u0689<\/i>\u00a0(\u06f2\u06f0\u06f2\u06f1). https:\/\/doi.org\/10.1038\/s41591-021-01274-0<\/p>\n

\u067e\u0648\u062a\u0627\u0631\u0627\u062c\u0648\u060c \u0627\u06cc\u0645\u060c \u062c\u06cc\u06a9\u0633\u0646\u060c \u0627\u06cc\u0645\u060c \u06a9\u0644\u06cc\u0646\u060c \u0627\u06cc\u0633.\u00a0et al.<\/i>\u00a0\u0633\u06cc\u0633\u062a\u0645\u0627\u062a\u06cc\u06a9 \u0633\u06a9\u0631\u06cc\u0646\u06cc\u0646\u06ab \u062f \u0647\u0686\u06cc\u0646\u0633\u0646 \u2013 \u06ab\u06cc\u0644\u0641\u0648\u0631\u0689 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0646\u0689\u0631\u0648\u0645 \u0644\u067e\u0627\u0631\u0647 \u0645\u0639\u0627\u0644\u062c\u0648\u064a \u0627\u0646\u067c\u064a \u0633\u06cc\u0646\u0633 \u0627\u0648\u0644\u06cc\u06ab\u0648\u0646\u06cc\u0648\u06a9\u0644\u06cc\u0648\u067c\u0627\u06cc\u0689\u0648\u0646\u0647 \u067e\u06cc\u0698\u0646\u064a.\u00a0\u0646\u06cc\u067c \u0645\u06cc\u0689<\/i>\u00a0(\u06f2\u06f0\u06f2\u06f1). https:\/\/doi.org\/10.1038\/s41591-021-01262-4<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"

\u0645\u0648\u0696 \u062e\u0648\u069a \u06cc\u0648 \u0686\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0685\u06cc\u0693\u0646\u0648 \u06a9\u06d0 \u062f RNA \u062f\u0631\u0645\u0644\u0646\u06d0 \u06a9\u0627\u0631\u0648\u0644\u0648 \u067e\u0647 \u0627\u0693\u0647 \u062f \u062f\u0648\u0647 \u062e\u0648\u0631\u0627 \u067e\u0647 \u0632\u0693\u0647 \u067e\u0648\u0631\u064a \u067e\u0631\u0645\u062e\u062a\u06ab \u0645\u0637\u0627\u0644\u0639\u0627\u062a\u0648 \u067e\u0627\u06cc\u0644\u06d0 \u0634\u0631\u06cc\u06a9\u06d0 \u06a9\u0693\u0648. \u062f\u0648\u0627\u0693\u0647 \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0631\u06cc\u0633\u0631\u0686 \u0641\u0627\u0624\u0646\u0688\u06cc\u0634\u0646 (PRF) \u0644\u062e\u0648\u0627 \u067e\u0647 \u06ab\u0689\u0647 \u062a\u0645\u0648\u06cc\u0644 \u0634\u0648\u064a \u0627\u0648 \u062f PRF \u0637\u0628\u064a \u0631\u06cc\u06cc\u0633 \u0689\u0627\u06a9\u067c\u0631 \u0644\u06cc\u0633\u0644\u064a \u06ab\u0648\u0631\u0689\u0646 \u0644\u062e\u0648\u0627 \u067e\u0647 \u06ab\u0689\u0647 \u0644\u06cc\u06a9\u0644 \u0634\u0648\u064a. <\/p>","protected":false},"author":2,"featured_media":12414,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,1],"tags":[],"class_list":["post-12401","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-uncategorized"],"yoast_head":"\nExciting breakthroughs in RNA Therapeutics for Progeria! | The Progeria Research Foundation<\/title>\n<meta name=\"description\" content=\"Two very exciting breakthrough studies on the use of RNA therapeutics in Progeria research.\u00a0 Both studies were co-funded by The Progeria Research Foundation (PRF) and co-authored by PRF\u2019s Medical Director, Dr. Leslie Gordon.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/ps\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Exciting breakthroughs in RNA Therapeutics for Progeria! | The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"Two very exciting breakthrough studies on the use of RNA therapeutics in Progeria research.\u00a0 Both studies were co-funded by The Progeria Research Foundation (PRF) and co-authored by PRF\u2019s Medical Director, Dr. Leslie Gordon.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.progeriaresearch.org\/ps\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/\" \/>\n<meta property=\"og:site_name\" content=\"The Progeria Research Foundation\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ProgeriaResearch\/\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-12T02:08:40+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-14T22:12:14+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2021\/03\/Carlos-with-crocheted-sloth-cropped.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"276\" \/>\n\t<meta property=\"og:image:height\" content=\"272\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Karen Betournay\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Exciting breakthroughs in RNA Therapeutics for Progeria! | The Progeria Research Foundation\" \/>\n<meta name=\"twitter:description\" content=\"Two very exciting breakthrough studies on the use of RNA therapeutics in Progeria research.\u00a0 Both studies were co-funded by The Progeria Research Foundation (PRF) and co-authored by PRF\u2019s Medical Director, Dr. Leslie Gordon.\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2021\/03\/Carlos-with-crocheted-sloth-cropped.jpg\" \/>\n<meta name=\"twitter:creator\" content=\"@Progeria\" \/>\n<meta name=\"twitter:site\" content=\"@Progeria\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Karen Betournay\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ar\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ar\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/\"},\"author\":{\"name\":\"Karen Betournay\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/2be6cec85c11aaef7a7602636c5b9946\"},\"headline\":\"Exciting breakthroughs in RNA Therapeutics for 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