{"id":8398,"date":"2020-11-02T18:57:17","date_gmt":"2020-11-02T23:57:17","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=8398"},"modified":"2022-12-09T06:43:20","modified_gmt":"2022-12-09T11:43:20","slug":"2020-workshop","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/ps\/2020\/11\/02\/2020-workshop\/","title":{"rendered":"\u062f PRF \u0644\u0633\u0645 \u0646\u0693\u06cc\u0648\u0627\u0644 \u0633\u0627\u06cc\u0646\u0633\u064a \u0648\u0631\u06a9\u0634\u0627\u067e"},"content":{"rendered":"

[et_pb_section fb_built=\u201d1\u2033 fullwidth=\u201don\u201d disabled_on=\u201doff|off|off\u201d _builder_version=\u201d4.16\u2033 border_width_bottom=\u201d55px\u201d border_color_bottom=\u201d#29327a\u201d locked=\u201doff\u201d global_colors_info=\u201d{}\u201d][et_pb_fullwidth_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/01\/2020WebinarBanner.png\u201d title_text=\u201d2020WebinarBanner\u201d _builder_version=\u201d4.16\u2033 custom_padding=\u201d20px||\u201d z_index_tablet=\u201d500\u2033 global_colors_info=\u201d{}\u201d]<\/p>\n

[\/et_pb_fullwidth_image][\/et_pb_section][et_pb_section fb_built=\u201d1\u2033 use_custom_gutter=\u201don\u201d gutter_width=\u201d1\u2033 specialty=\u201don\u201d padding_left_1=\u201d35px\u201d padding_left_2=\u201d35px\u201d padding_2_tablet=\u201d||0px\u201d padding_2_phone=\u201d||0px\u201d padding_2_last_edited=\u201don|desktop\u201d module_class_1=\u201dsidebar-secondary-nav\u201d module_class=\u201dhandprint-bg\u201d _builder_version=\u201d4.16\u2033 background_image=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/blue-handprint-only.png\u201d parallax=\u201don\u201d parallax_method=\u201doff\u201d inner_width=\u201d100%\u201d \u062f\u0627\u062e\u0644\u064a_ \u0627\u0639\u0638\u0645\u064a_\u0686\u0648\u06a9\u06cd = "100%" \u062f\u0648\u062f\u06cc\u0632_\u067e\u06cc\u0689\u06cc\u0646\u06ab = "0|0px|54px|0px|\u063a\u0644\u0637|\u063a\u0644\u0637" z_index_tablet = "500" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u0627\u067c_\u067c\u0627\u067e = "10px" \u062f \u0633\u0631\u062d\u062f_\u0631\u0646\u06ab_\u067c\u0627\u067e = "#8fd2ed" \u06a9\u0627\u0631\u0648\u0644_\u06a9\u0633\u067c\u0645_\u0686\u0648\u06a9\u0627\u067c = "\u067e\u0647" \u062f \u0637\u0648\u0644_\u06cc\u0648\u0646\u067c = "\u0628\u0646\u062f" \u062f\u0648\u062f\u06cc\u0632_\u0686\u0648\u06a9\u0627\u067c_\u067e\u0631\u0633\u0646\u067c = "100%" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0627\u0646\u0641\u0648 = "{}"][et_pb_column \u0689\u0648\u0644 = "1_4" _\u062c\u0648\u0693\u0648\u0646\u06a9\u06cc_\u0648\u0631\u0698\u0646 = "4.16" \u062f\u0648\u062f\u06cc\u0632_\u067e\u06cc\u0689\u06cc\u0646\u06ab = "||" global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d||\u201d][et_pb_sidebar area=\u201det_pb_widget_area_24\u2033 disabled_on=\u201don|on|off\u201d admin_label=\u201dScientific meetings sidebar\u201d module_class=\u201dsubpage-sidebars\u201d _builder_version=\u201d4.16\u2033 text_orientation=\u201dleft\u201d animation_style=\u201dfade\u201d hover_enabled=\u201d0\u2033 z_index_tablet=\u201d500\u2033 border_width_right=\u201d5px\u201d global_colors_info=\u201d{}\u201d sticky_enabled=\u201d0\u2033 locked=\u201doff\u201d][\/et_pb_sidebar][\/et_pb_column][et_pb_column type=\u201d3_4\u2033 specialty_columns=\u201d3\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d||\u201d][et_pb_row_inner custom_padding_last_edited=\u201don|phone\u201d _builder_version=\u201d4.16\u2033 custom_padding=\u201d39.4375px|35px|35px||false|false\u201d custom_padding_tablet=\u201d|35px||35px||real\u201d custom_padding_phone=\u201d\u201d animation_direction=\u201dtop\u201d global_colors_info=\u201d{}\u201d][et_pb_column_inner saved_specialty_column_type=\u201d3_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d||\u201d][et_pb_text _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d global_colors_info=\u201d{}\u201d]<\/p>\n

\u0644\u0647 370 \u0685\u062e\u0647 \u0689\u06cc\u0631<\/strong> \u0685\u062e\u0647 \u0631\u0627\u062c\u0633\u062a\u0631 \u06a9\u0648\u0646\u06a9\u064a 30<\/strong> \u0647\u06cc\u0648\u0627\u062f\u0648\u0646\u0648 \u0632\u0645\u0648\u0696 \u067e\u0647 1 \u06a9\u06d0 \u06ab\u0689\u0648\u0646 \u0648\u06a9\u0693st<\/sup> \u062a\u0644 \u062f \u0648\u06cc\u0628 \u067e\u0631 \u0628\u0646\u0633\u067c \u0639\u0644\u0645\u064a \u063a\u0648\u0646\u0689\u0647!<\/h4>\n

[\/et_pb_text][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/07\/Registrant-Map-1.jpg\u201d title_text=\u201dRegistrant-Map\u201d align=\u201dcenter\u201d admin_label=\u201dmap\u201d _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d custom_margin=\u201d10px||20px||false|false\u201d global_colors_info=\u201d{}\u201d][\/et_pb_image][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/12\/Complete-Photo.jpg\u201d title_text=\u201dComplete-Photo\u201d align=\u201dcenter\u201d admin_label=\u201dparticipants\u201d _builder_version=\u201d4.16\u2033 _module_preset="\u0689\u06cc\u0641\u0627\u0644\u067c" custom_margin="10px||15px||false|false" global_colors_info="{}"][\/et_pb_image][et_pb_text admin_label="\u062f \u0648\u06cc\u0689\u06cc\u0648 \u06a9\u0644\u067e \u0645\u062a\u0646" _builder_version="4.16" _module_preset="\u0689\u06cc\u0641\u0627\u0644\u067c" global_colors_info="{}"]<\/p>\n

\u0645\u0648\u0696 \u0647\u06cc\u0644\u0647 \u0644\u0631\u0648 \u0686\u06d0 \u062a\u0627\u0633\u0648 \u0632\u0645\u0648\u0696 \u062f 2020 \u0646\u0693\u06cc\u0648\u0627\u0644 \u0648\u0631\u06a9\u0634\u0627\u067e \u0685\u062e\u0647 \u062f \u062f\u06d0 \u06a9\u0644\u06cc\u067e \u0685\u062e\u0647 \u062e\u0648\u0646\u062f \u0648\u0627\u062e\u0644\u0626\u060c
"\u062f \u0627\u0645\u06a9\u0627\u0646\u0627\u062a\u0648 \u0685\u06cc\u0693\u0646\u0647\u060c \u062f \u0698\u0648\u0646\u062f \u067e\u0631\u0627\u062e\u0648\u0644" \u0648\u06cc\u0628\u06cc\u0646\u0627\u0631<\/h4>\n

[\/et_pb_text][et_pb_video src=\u201dhttps:\/\/www.youtube.com\/watch?v=pedD1zXVw1o&feature=youtu.be\u201d _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d global_colors_info=\u201d{}\u201d][\/et_pb_video][et_pb_text admin_label=\u201ddisclaimer\u201d _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d global_colors_info=\u201d{}\u201d]<\/p>\n

\u00a0\u067c\u0648\u0644 \u062d\u0642\u0648\u0646\u0647 \u062e\u0648\u0646\u062f\u064a \u062f\u064a. \u0645\u0647\u0631\u0628\u0627\u0646\u064a \u0648\u06a9\u0693\u0626 \u062f\u0627 \u067e\u0631\u06cc\u0632\u0646\u067c\u0634\u0646 \u067e\u0647 \u0647\u06cc\u0685 \u0689\u0648\u0644 \u0689\u0627\u0648\u0646\u0644\u0648\u0689 \u060c \u06a9\u0627\u067e\u064a \u060c \u062a\u0648\u0632\u06cc\u0639 \u06cc\u0627 \u062a\u0631\u0645\u06cc\u0645 \u0645\u0647 \u06a9\u0648\u0626.<\/i><\/p>\n

[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d custom_padding=\u201d|35px||||\u201d global_colors_info=\u201d{}\u201d][et_pb_column_inner saved_specialty_column_type=\u201d3_4\u2033 _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d global_colors_info=\u201d{}\u201d][et_pb_text admin_label=\u201d\u062f \u0686\u06cc\u067c \u067e\u0648\u069a\u062a\u0646\u06d0\u201d _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d global_colors_info=\u201d{}\u201d]<\/p>\n

\u0628\u06d0 \u0681\u0648\u0627\u0628\u0647 \u0686\u06cc\u0679 \u067e\u0648\u069a\u062a\u0646\u06d0<\/strong><\/h4>\n

[\/et_pb_text][et_pb_toggle title="\u0689\u0627\u06a9\u067c\u0631 \u0641\u0631\u0627\u0646\u0633\u0633 \u06a9\u0648\u0644\u06cc\u0646\u0632 \u062a\u0647: \u067e\u0648\u069a\u062a\u0646\u0647: \u062f \u0645\u0646\u0635\u0648\u0631 \u0627\u0645\u06cc\u062c\u064a \u0685\u062e\u0647: \u0689\u0627\u06a9\u067c\u0631 \u06a9\u0648\u0644\u06cc\u0646\u0632\u060c \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u062f PPPMO \u0628\u0627\u06cc\u0648 \u0648\u06cc\u0634 \u067e\u0647 \u0633\u06cc\u0633\u067c\u0645\u06cc\u06a9 \u0689\u0648\u0644 \u0644\u06cc\u062f\u0644\u06cc \u062f\u06cc "open_toggle_background_color="#f7f7f7" closed_toggle_text_color="#ffffff" closed_toggle_background_color="#00b2e2" icon_color="#ffc15e" open_icon_color="#ffc15e" admin_label="\u06a9\u0648\u0644\u06cc\u0646\u0633 \u067e\u0648\u069a\u062a\u0646\u06d0 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0647" _builder_version="4.16" _module_preset="default" title_text_color="#00b2e2" title_font="||||||" \u062f \u0634\u0627\u0644\u064a\u062f_\u0631\u0646\u06ab="#ffffff" \u062f\u0648\u062f\u06cc\u0632_\u062d\u0627\u0635\u0644="||25px" \u062f\u0648\u062f\u06cc\u0632_\u067e\u0689\u06cc\u0646\u06ab="|50px||50px||\u0631\u06cc\u069a\u062a\u06cc\u0627" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u06cd_\u067c\u0648\u0644="0px" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0645\u0639\u0644\u0648\u0645\u0627\u062a="{}"]<\/p>\n


\"\"\u0681\u0648\u0627\u0628:<\/strong> \u062f PK\/PD \u0645\u0637\u0627\u0644\u0639\u06d0 \u067e\u0647 \u0632\u0693\u0647\u060c \u0634\u0631\u06cc\u0627\u0646 \u0627\u0648 \u067e\u069a\u062a\u0648\u0631\u06ab\u0648 \u06a9\u06d0 \u062f 100% \u0628\u0627\u06cc\u0648 \u0645\u0648\u062c\u0648\u062f\u06cc\u062a \u067e\u0647 \u06ab\u0648\u062a\u0647 \u06a9\u0648\u064a. \u067e\u069a\u062a\u0648\u0631\u06ab\u064a \u06cc\u0648\u0627\u0632\u06cc\u0646\u06cc \u0646\u0633\u062c \u0648 \u0686\u06cc\u0631\u06d0 \u0686\u06d0 \u062f \u0647\u0633\u067c\u0648\u0644\u0648\u0698\u06cc\u06a9\u064a \u0627\u0632\u0645\u0648\u06cc\u0646\u06d0 \u0627\u0648 PK\/PD \u0645\u0639\u0644\u0648\u0645\u0627\u062a\u0648 \u067e\u0631\u0627\u0633\u0627\u0633 \u062f \u0631\u0627\u067c\u0648\u0644\u06cc\u062f\u0648 \u0648\u0693\u0627\u0646\u062f\u06cc\u0632 \u0634\u0648\u06cc \u0648. \u062f SRP-2001 \u0648\u0627\u062d\u062f \u062f\u0648\u0632 \u0627\u062f\u0627\u0631\u0647 \u069a\u0648\u062f\u0644\u06d0 \u0686\u06d0 PPMO \u067e\u0647 \u0686\u067c\u06a9\u06cd \u0633\u0631\u0647 \u062f \u0632\u0693\u0647 \u0685\u062e\u0647 \u067e\u0627\u06a9 \u0634\u0648\u06cc (\u067e\u0647 2 \u0633\u0627\u0639\u062a\u0648\u0646\u0648 \u06a9\u06d0) \u060c \u067e\u0647 4 \u0633\u0627\u0639\u062a\u0648\u0646\u0648 \u06a9\u06d0 \u062f \u0627\u0648\u0631\u067c\u0627 \u0685\u062e\u0647 \u067e\u0627\u06a9 \u0634\u0648\u06cc \u060c \u0645\u06ab\u0631 \u067e\u0647 \u067e\u069a\u062a\u0648\u0631\u06ab\u0648 \u06a9\u06d0 \u062a\u0631 48 \u0633\u0627\u0639\u062a\u0648\u0646\u0648 \u067e\u0648\u0631\u06d0 \u062f\u0648\u0627\u0645 \u0644\u0631\u064a. \u0645\u0642\u062f\u0627\u0631\u064a ddPCR \u062f \u067e\u0648\u067c\u06a9\u064a \u067e\u0631\u062a\u0647 \u067e\u0647 \u067c\u0648\u0644\u0648 \u0646\u0633\u062c\u0648\u0646\u0648 \u06a9\u06d0 \u062f G608G \u06a9\u0631\u06cc\u067e\u067c\u06cc\u06a9 \u0633\u067e\u0644\u0627\u06cc\u0633 \u0645\u062e\u0646\u06cc\u0648\u06cc \u0641\u0639\u0627\u0644\u06cc\u062a \u069a\u0648\u062f\u0644\u06cc (\u062f \u0627\u0631\u0648\u067c\u0627\u060c \u0632\u0693\u0647\u060c \u067e\u069a\u062a\u0648\u0631\u06ab\u0648\u060c \u0681\u064a\u06ab\u0631\u060c \u06a9\u0648\u0627\u0689\u0631\u06cc\u0633\u06cc\u067e\u0633\u060c \u0647\u0689\u0648\u06a9\u064a)\u060c \u06a9\u0647 \u0685\u0647 \u0647\u0645 \u0641\u0639\u0627\u0644\u06cc\u062a \u062f \u0646\u0633\u062c \u067e\u0647 \u0627\u0633\u0627\u0633 \u062a\u0648\u067e\u06cc\u0631 \u0644\u0631\u064a.<\/p>\n

\u0641\u0631\u0627\u0646\u0633\u06cc\u0633\u060c \u0645\u0627\u06cc\u06a9 \u0627\u0648 \u0648\u06cc\u0646<\/em><\/p>\n

[\/et_pb_toggle][et_pb_toggle title="\u0689\u0627\u06a9\u067c\u0631 \u067e\u0646\u06a9 \u0634\u0627\u0647 \u0627\u0648 \u0689\u0627\u06a9\u067c\u0631 \u0641\u0631\u0627\u0646\u0633\u06cc\u0633\u06a9\u0648 \u0645\u0648\u0633\u0648\u0645\u06cc\u0686\u064a \u062a\u0647: \u067e\u0648\u069a\u062a\u0646\u0647: \u062f RVB \u0685\u062e\u0647: \u0627\u06cc\u0627 \u062f \u0645\u06ab\u0646\u06cc\u0632\u06cc\u0645 \/ \u06a9\u0644\u0633\u06cc\u0645 \u0627\u062e\u06cc\u0633\u062a\u0644 \u062f HGPS \u0633\u0631\u0647 \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u06a9\u06d0 \u062f \u06a9\u0644\u0633\u06cc\u0641\u06cc\u06a9\u06cc\u0634\u0646 \u06a9\u0686\u0647 \u067c\u0627\u06a9\u0644\u06cc \u0634\u064a\u061f" open_toggle_background_color="#f7f7f7" closed_toggle_text_color="#ffffff" closed_toggle_background_color="#00b2e2" icon_color="#ffc15e" open_icon_color="#ffc15e" admin_label="\u0634\u0627\u0647 \u0627\u0648 \u0645\u0648\u0633\u0648\u0645\u06cc\u0686\u064a \u067e\u0648\u069a\u062a\u0646\u0647 \u0627\u0648 \u0681\u0648\u0627\u0628" _builder_version="4.16" _module_preset="default" title_text_color="#00b2e2" title_font="||||||" \u062f \u0634\u0627\u0644\u064a\u062f_\u0631\u0646\u06ab="#ffffff" \u062f\u0648\u062f\u06cc\u0632_\u062d\u0627\u0635\u0644="||25px" \u062f\u0648\u062f\u06cc\u0632_\u067e\u0689\u06cc\u0646\u06ab="|50px||50px||\u0631\u06cc\u069a\u062a\u06cc\u0627" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u06cd_\u067c\u0648\u0644="0px" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0645\u0639\u0644\u0648\u0645\u0627\u062a="{}"]<\/p>\n

\"\"<\/strong>\u0681\u0648\u0627\u0628:<\/strong>\u062f \u062f\u06d0 \u067e\u0648\u069a\u062a\u0646\u06d0 \u067e\u0647 \u0627\u0693\u0647\u060c \u0635\u0627\u062f\u0642\u0627\u0646\u0647\u060c \u0632\u0647 \u062f \u062f\u06d0 \u067e\u0648\u069a\u062a\u0646\u06d0 \u067e\u0647 \u0681\u0648\u0627\u0628 \u0646\u0647 \u067e\u0648\u0647\u06cc\u0696\u0645. \u067e\u0647 \u06cc\u0648 \u0639\u0627\u062f\u064a \u0628\u0627\u0644\u063a \u06a9\u06d0\u060c \u06a9\u0647 \u0685\u0647 \u0647\u0645\u060c \u0645\u0648\u0696 \u062f \u0648\u0627\u0644\u0648\u0648\u0644\u0631 \u06a9\u06cc\u0644\u06a9\u06cc\u0641\u06cc\u06a9\u06cc\u0634\u0646 \u062f\u0631\u062c\u06d0 \u062f Mg\/Ca \u062f \u0627\u062e\u06cc\u0633\u062a\u0644\u0648 \u0633\u0631\u0647 \u062a\u0693\u0627\u0648 \u0646\u0647 \u0644\u0631\u0648\u060c \u062f \u0648\u0632\u0646 \u0632\u06cc\u0627\u062a\u0648\u0627\u0644\u064a \u0627\u062d\u062a\u0645\u0627\u0644 \u062f \u0646\u0648\u0631\u0648 \u0641\u06a9\u062a\u0648\u0631\u0648\u0646\u0648 \u0644\u0647 \u0627\u0645\u0644\u0647 \u0648\u064a.<\/p>\n

\u0689\u0627\u06a9\u067c\u0631 \u067e\u0646\u06a9 \u0634\u0627\u0647<\/em><\/p>\n

 <\/p>\n

 <\/p>\n

\"\"\u0681\u0648\u0627\u0628: <\/strong>\u0632\u0647 \u062f \u0689\u0627\u06a9\u067c\u0631 \u0634\u0627\u0647 \u0646\u0638\u0631 \u0633\u0631\u0647 \u0645\u0648\u0627\u0641\u0642 \u06cc\u0645. \u069a\u0627\u06cc\u064a \u067e\u0647 HGPS \u06a9\u06d0 \u062f \u0648\u0627\u0644\u0648 \u06a9\u06cc\u0644\u06a9\u06cc\u0634\u0646 \u0644\u0627\u0645\u0644\u0648\u0646\u0647 \u0644\u0647 \u0647\u063a\u0647 \u0685\u062e\u0647 \u062a\u0648\u067e\u06cc\u0631 \u0648\u0644\u0631\u064a \u0686\u06d0 \u0645\u0648\u0696 \u06cc\u06d0 \u067e\u0647 \u0632\u0693\u0648 \u0646\u0627\u0631\u0648\u063a\u0627\u0646\u0648 \u06a9\u06d0 \u06ab\u0648\u0631\u0648. \u0632\u0647 \u062f Ca \u0627\u0648 Mg \u0645\u06cc\u067c\u0627\u0628\u0648\u0644\u06cc\u0632\u0645 \u067e\u0647 \u0627\u0693\u0647 \u0647\u0645 \u0647\u06cc\u0685 \u067e\u0648\u0647\u0647 \u0646\u0647 \u0644\u0631\u0645.<\/p>\n

\u0689\u0627\u06a9\u067c\u0631 \u0641\u0631\u0627\u0646\u0633\u06cc\u0633\u06a9\u0648 \u0645\u0648\u0633\u0648\u0645\u06cc\u0633\u064a<\/em><\/p>\n

\u00a0<\/strong><\/p>\n

[\/et_pb_toggle][et_pb_toggle title=\u201d \u0689\u0627\u06a9\u067c\u0631 \u0648\u06cc\u0633\u06cc\u0646\u067c \u0627\u0646\u062f\u0631\u06cc\u0633 \u062a\u0647: \u067e\u0648\u069a\u062a\u0646\u0647: \u062f \u0627\u0646\u062f\u0631\u06d0 \u0645\u0648\u0646\u067c\u06cc\u0631\u0648 \u062f\u0627 \u0631\u0648\u0686\u0627 \u0685\u062e\u0647 - \u062f \u0645\u06cc\u0634\u06cc\u06ab\u0627\u0646 \u067e\u0648\u0647\u0646\u062a\u0648\u0646: \u0627\u06cc\u0627 \u0647\u063a\u0647 \u0645\u0648\u0696\u06a9\u0627\u0646 \u0686\u06d0 \u0644\u0627\u0645\u06cc\u0646 A \u0646\u0644\u0631\u064a DCM \u0631\u0627\u0645\u06cc\u0646\u0681\u062a\u0647 \u06a9\u0648\u064a\u061f\u201d open_toggle_background_color=\u201d#f7f7f7\u2033 closed_toggle_text_color=\u201d#ffffff\u201d closed_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon_color=\u201d#ffc15e\u201d admin_label=\u201d\u0627\u0646\u0689\u0631\u06cc\u0633 \u067e\u0648\u069a\u062a\u0646\u0647 \u0627\u0648 \u0681\u0648\u0627\u0628\u201d _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d title_text_color=\u201d#00b2e2\u2033 title_font=\u201d||||||\u201d \u062f \u0634\u0627\u0644\u064a\u062f_\u0631\u0646\u06ab="#ffffff" \u062f\u0648\u062f\u06cc\u0632_\u062d\u0627\u0635\u0644="||25px" \u062f\u0648\u062f\u06cc\u0632_\u067e\u0689\u06cc\u0646\u06ab="|50px||50px||\u0631\u06cc\u069a\u062a\u06cc\u0627" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u06cd_\u067c\u0648\u0644="0px" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0645\u0639\u0644\u0648\u0645\u0627\u062a="{}"]<\/p>\n

\"\"\u0681\u0648\u0627\u0628: <\/strong>\u062f \u0644\u0627\u0645\u06cc\u0646 A\/C \u0646\u0644 (Lmna<\/em>-\/-<\/sup>\u062f \u0645\u0648\u0696\u06a9 \u0645\u0627\u0689\u0644 DCM \u062a\u0647 \u0648\u062f\u0647 \u0648\u0631\u06a9\u0648\u064a \u062f \u0632\u0693\u0647 \u062f \u0641\u0639\u0627\u0644\u06cc\u062a \u0644\u0647 \u0644\u0627\u0633\u0647 \u0648\u0631\u06a9\u0648\u0644\u0648 \u0633\u0631\u0647. \u0628\u0631\u0633\u06d0\u0631\u0647 \u067e\u0631\u062f\u06d0\u060c \u062f\u0627 \u0645\u0648\u0696\u06a9\u0627\u0646 \u062f \u0632\u0693\u0647 \u067e\u0647 \u062c\u0631\u06cc\u0627\u0646 \u06a9\u06d0 \u0646\u06cc\u0645\u06ab\u0693\u062a\u06cc\u0627\u0648\u06d0 \u0627\u0648 \u067e\u0631\u0627\u062e\u0647 \u0632\u0693\u0647 \u0641\u0627\u06cc\u0628\u0631\u0631\u0648\u0633\u0633\u060c \u0627\u0648 \u062f 5-8 \u0627\u0648\u0646\u06cc\u0648 \u067e\u0647 \u0639\u0645\u0631 \u06a9\u06d0 \u062f \u0648\u062e\u062a \u0685\u062e\u0647 \u0645\u062e\u06a9\u06d0 \u0645\u0693\u06cc\u0646\u0647 \u0685\u0631\u06ab\u0646\u062f\u0648\u064a (\u0627\u06ab\u0633\u067c \u0627\u0648 \u0627\u0644.\u060c 2018\u061b \u0641\u0631\u0648\u06a9 \u0627\u0648 \u0627\u0644.\u060c 2012\u061b \u0633\u0644\u06cc\u0648\u0627\u0646\u060c 1999). \u067e\u0647 \u0647\u0631\u0635\u0648\u0631\u062a\u060c \u062f \u0645\u0648\u0696\u06a9 \u0645\u0627\u0689\u0644\u0648\u0646\u0647 \u0686\u06d0 \u06cc\u0648\u0627\u0632\u06d0 \u0644\u0627\u0645\u06cc\u0646 A (Fong et al., 2006) \u06cc\u0627 lamin C (Coffinier et al., 2010) \u0646\u0644\u0631\u064a \u062f \u0632\u0693\u0647 \u0639\u06cc\u0628\u0648\u0646\u0647 \u0646\u0647 \u069a\u06cc\u06d0 \u0627\u0648 \u0646\u0648\u0631\u0645\u0627\u0644 \u0639\u0645\u0631 \u0644\u0631\u064a.<\/p>\n

\u062d\u0648\u0627\u0644\u06d0:
<\/strong>Auguste, G., Gurha, P., Lombardi, R., Coarfa, C., Willerson, JT, & Marian, AJ (2018). \u067e\u0647 \u0632\u0693\u0647 \u06a9\u06d0 \u062f \u0641\u0639\u0627\u0644 FOXO \u067c\u0631\u0627\u0646\u0633\u06a9\u0631\u067e\u0634\u0646 \u0641\u06a9\u062a\u0648\u0631\u0648\u0646\u0648 \u0641\u0634\u0627\u0631 \u062f \u0644\u0627\u0645\u06cc\u0646\u0648\u067e\u06cc\u062a\u064a\u0632 \u067e\u0647 \u0645\u0648\u0696\u06a9 \u0645\u0627\u0689\u0644 \u06a9\u06d0 \u0628\u0642\u0627 \u0627\u0648\u0696\u062f\u0648\u064a<\/em>. https:\/\/doi.org\/10.1161\/CIRCRESAHA.117.312052<\/a><\/p>\n

\u06a9\u0648\u0641\u06cc\u0646\u06cc\u0631\u060c \u0633\u06cc\u060c \u062c\u0648\u0646\u06ab\u060c \u0627\u06cc\u0686 \u062c\u06d2\u060c \u0644\u06cc\u060c \u0632\u06cc\u060c \u0646\u0648\u0628\u0648\u0645\u0648\u0631\u06cc\u060c \u0633\u06cc\u060c \u06cc\u0648\u0646\u060c \u06cc\u0648 \u062c\u06d2\u060c \u0641\u0627\u0631\u0628\u0631\u060c EA\u060c \u0689\u06cc\u0648\u06cc\u0633\u060c \u0628\u06cc \u0627\u06cc\u0633\u060c \u0648\u06cc\u0646\u0633\u067c\u06cc\u0646\u060c \u0627\u06cc\u0645 \u0627\u06cc\u0645\u060c \u06cc\u0627\u0646\u06ab\u060c \u0627\u06cc\u0633 \u0627\u06cc\u0686\u060c \u0644\u0627\u0645\u0631\u0689\u06cc\u0646\u06ab\u060c \u062c\u06d2\u060c \u0641\u0631\u0627\u0647\u0627\u0646\u064a\u060c JN\u060c \u0628\u06cc\u0646\u067c\u0648\u0644\u06cc\u0644\u0627 LA, Fong, LG, & Young, SG (2010). \u062f \u0644\u0627\u0645\u06cc\u0646 A \u0645\u0633\u062a\u0642\u06cc\u0645 \u062a\u0631\u06a9\u06cc\u0628\u060c \u062f \u067e\u0631\u06cc\u0644\u0627\u0645\u06cc\u0646 \u067e\u0631\u0648\u0633\u0633 \u06a9\u0648\u0644\u0648 \u0685\u062e\u0647 \u062a\u06cc\u0631\u06cc\u0696\u064a\u060c \u067e\u0647 \u0641\u0627\u06cc\u0628\u0631\u0648\u0628\u0644\u0627\u0633\u067c\u0648\u0646\u0648 \u06a9\u06d0 \u062f \u0646\u0627\u067e\u0627\u06a9\u0648 \u0646\u06cc\u0648\u06a9\u0644\u06cc\u0648 \u0644\u0627\u0645\u0644 \u06a9\u06cc\u0696\u064a \u0645\u06ab\u0631 \u067e\u0647 \u0645\u0648\u0696\u06a9\u0627\u0646\u0648 \u06a9\u06d0 \u062f \u06a9\u0634\u0641 \u0648\u0693 \u0631\u0646\u0681\u067e\u0648\u0647\u0646\u0647 \u0634\u062a\u0648\u0646 \u0646\u0644\u0631\u064a. \u062f \u0628\u06cc\u0648\u0644\u0648\u0698\u06cc\u06a9\u064a \u06a9\u06cc\u0645\u06cc\u0627 \u0698\u0648\u0631\u0646\u0627\u0644<\/em>, 285<\/em>(27)\u060c 20818\u201320826. https:\/\/doi.org\/10.1074\/jbc.M110.128835<\/a><\/p>\n

Fong, LG, Bergo, MO, Young, SG, Fong, LG, Ng, JK, Lammerding, J. Vickers, TA, Meta, M., Cot\u00e9, N., Gavino, B., Qiao, X., Chang , SY, Young, SR, Yang, SH, Stewart, CL, Lee, RT, Bennett, CF, Bergo, MO, & Young, SG (2006). Prelamin A \u0627\u0648 lamin A \u062f\u0627\u0633\u06d0 \u069a\u06a9\u0627\u0631\u064a \u0686\u06d0 \u067e\u0647 \u0627\u067c\u0648\u0645\u064a \u0644\u0627\u0645\u06cc\u0646\u0647 \u06a9\u06d0 \u062f \u062a\u0648\u0632\u06cc\u0639 \u0648\u0693 \u0648\u064a. \u062f \u06a9\u0644\u06cc\u0646\u06cc\u06a9\u064a \u062a\u062d\u0642\u06cc\u0642\u0627\u062a\u0648 \u0698\u0648\u0631\u0646\u0627\u0644<\/em>, 116<\/em>(\u06f3)\u060c \u06f7\u06f4\u06f3\u2013\u06f7\u06f5\u06f2. https:\/\/doi.org\/10.1172\/JCI27125.with<\/a><\/p>\n

\u0641\u0631\u0627\u06a9\u060c \u0622\u0631 \u0627\u06cc\u0644\u060c \u0686\u0646\u060c \u0627\u06cc\u0633 \u0633\u06cc\u060c \u062f\u0627\u060c \u0689\u064a\u060c \u0641\u0631\u06cc\u067c\u060c \u0627\u06cc\u060c \u0644\u0627\u0648\u060c \u0633\u064a\u060c \u0628\u0631\u0627\u0648\u0646\u060c \u0633\u064a\u060c \u067e\u0627\u06a9\u060c \u0689\u064a \u0627\u06cc\u0646\u060c \u0648\u0627\u0646\u06ab\u060c \u06cc\u0648\u060c \u0645\u0648\u0686\u06cc\u0631\u060c \u0627\u06d0\u060c \u0648\u0631\u0645\u0646\u060c \u0627\u06cc\u0686 \u062c\u06d2\u060c \u0633\u0627\u0646\u062a\u0627\u0646\u0627\u060c \u0627\u06cc\u0644 \u0627\u06cc\u0641\u060c Ladiges, WC, Rabinovitch, PS, & Kennedy, BK (2012). \u062f cardiomyocyte-\u0681\u0627\u0646\u06ab\u0693\u064a \u0644\u0627\u0645\u06cc\u0646 A \u0685\u0631\u06ab\u0646\u062f\u0648\u0646\u0647 \u067e\u0647 Lmna-\/- \u0645\u0648\u0696\u06a9\u0627\u0646\u0648 \u06a9\u06d0 \u062f \u0632\u0693\u0647 \u0641\u0639\u0627\u0644\u06cc\u062a \u069a\u0647 \u06a9\u0648\u064a. PLOS ONE<\/em>, 7<\/em>(\u06f8)\u060c \u06f1-\u06f9. https:\/\/doi.org\/10.1371\/journal.pone.0042918<\/a><\/p>\n

\u0633\u0644\u06cc\u0648\u0627\u0646\u060c T. (1999). \u062f A-\u0689\u0648\u0644 \u0644\u0627\u0645\u06cc\u0646 \u0628\u06cc\u0627\u0646 \u0644\u0647 \u0644\u0627\u0633\u0647 \u0648\u0631\u06a9\u0648\u0644 \u062f \u0627\u067c\u0648\u0645\u064a \u0644\u0641\u0627\u0641\u06d0 \u0628\u0634\u067e\u0693\u062a\u06cc\u0627 \u0633\u0631\u0647 \u0645\u0648\u0627\u0641\u0642\u062a \u06a9\u0648\u064a \u0686\u06d0 \u062f \u0639\u0636\u0644\u0627\u062a\u0648 \u0689\u06cc\u0633\u067c\u0631\u0648\u0641\u064a \u0644\u0627\u0645\u0644 \u06a9\u06cc\u0696\u064a. \u062f \u062d\u062c\u0631\u0648 \u0628\u06cc\u0648\u0644\u0648\u0698\u064a \u0698\u0648\u0631\u0646\u0627\u0644<\/em>, 147<\/em>(\u06f5)\u060c \u06f9\u06f1\u06f3-\u06f9\u06f2\u06f0. https:\/\/doi.org\/10.1083\/jcb.147.5.913<\/a><\/p>\n

[\/et_pb_toggle][et_pb_toggle title=\u201d \u0689\u0627\u06a9\u067c\u0631 \u062c\u06cc\u0648\u0627\u0646\u0627 \u0644\u0627\u067c\u0627\u0646\u0632\u064a \u062a\u0647: \u062f \u0689\u0627\u06a9\u067c\u0631 \u0644\u0627\u067c\u0627\u0646\u0632\u064a \u0644\u067e\u0627\u0631\u0647 \u062f\u0648\u0647 \u067e\u0648\u069a\u062a\u0646\u06d0 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0647 \u0644\u0627\u0646\u062f\u06d0 \u0644\u06cc\u0633\u062a \u0634\u0648\u064a \u062f\u064a.\u201d open_toggle_background_color=\u201d#f7f7f7\u2033 closed_toggle_text_color=\u201d#ffffff\u201d closed_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon_color=\u201d#ffc15e\u201d admin_label=\u201d\u0644\u067c\u0627\u0646\u0632\u064a \u067e\u0648\u069a\u062a\u0646\u06d0 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0647 2\u2033 _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d title_text_color=\u201d#00b2e2\u2033 title_font=\u201d||||||\u201d \u062f \u0634\u0627\u0644\u064a\u062f_\u0631\u0646\u06ab="#ffffff" \u062f\u0648\u062f\u06cc\u0632_\u062d\u0627\u0635\u0644="||25px" \u062f\u0648\u062f\u06cc\u0632_\u067e\u0689\u06cc\u0646\u06ab="|50px||50px||\u0631\u06cc\u069a\u062a\u06cc\u0627" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u06cd_\u067c\u0648\u0644="0px" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0645\u0639\u0644\u0648\u0645\u0627\u062a="{}"]<\/p>\n

\"\"\u067e\u0648\u069a\u062a\u0646\u0647:<\/span> <\/strong>\u062f \u067c\u0627\u0645 \u0645\u06cc\u0633\u062a\u06cc\u0644\u064a \u0685\u062e\u0647: \u067e\u0647 \u0685\u0627\u0631\u0648\u06cc\u0648 \u06a9\u06d0 \u062f \u0644\u0648\u0646\u0627\u0641\u0631\u0646\u06cc\u0628 + \u062a\u0648\u0632\u06cc\u0644\u06cc\u0632\u0648\u0645\u0627\u0628 \u062f\u0631\u0645\u0644\u0646\u0647 \u0685\u0648\u0645\u0631\u0647 \u0648\u062e\u062a \u0648\u0647\u061f
\u0681\u0648\u0627\u0628:<\/span> <\/strong>\u0645\u0648\u0696 \u062f \u0647\u06cc\u062a\u0631\u0648\u0632\u06cc\u06ab\u0648\u0633 \u067e\u0647 \u062d\u06cc\u0648\u0627\u0646\u0627\u062a\u0648 \u06a9\u06d0 \u0644\u0648\u0645\u0693\u0646\u06cd \u062a\u062c\u0631\u0628\u0647 \u062a\u0631\u0633\u0631\u0647 \u06a9\u0693\u0647 \u0686\u06d0 \u0644\u0647 22 \u0627\u0648\u0646\u06cd \u0685\u062e\u0647 \u062a\u0631 30 \u0627\u0648\u0646\u06cd \u067e\u0648\u0631\u06d0 \u067e\u06cc\u0644 \u06a9\u06cc\u0696\u064a. \u0645\u0648\u0696 \u063a\u0648\u0627\u0693\u0648 \u062f \u0648\u0632\u0646 \u067e\u0647 \u0632\u06cc\u0627\u062a\u0648\u0627\u0644\u064a \u0628\u0627\u0646\u062f\u06d0 \u062f \u0627\u063a\u06cc\u0632 \u0627\u0631\u0632\u0648\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u067e\u062f\u06d0 \u0648\u062e\u062a \u0686\u0648\u06a9\u0627\u067c \u062a\u0645\u0631\u06a9\u0632 \u0648\u06a9\u0693\u0648 \u0686\u06d0 \u0645\u062e\u06a9\u06d0 \u062f \u062a\u0648\u06a9\u06cc\u0644\u06cc\u0632\u0648\u0645\u0627\u0628 \u0633\u0631\u0647 \u0644\u06cc\u062f\u0644 \u0634\u0648\u06cc \u0648.<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: <\/strong><\/span>\u0644\u0647 \u0633\u06ab\u0648\u0646\u0632\u0627\u0644\u0648 \u0685\u062e\u0647: \u069a\u06a9\u0644\u06d0 \u06a9\u06cc\u0633\u0647 \u062c\u06cc\u0648\u0627\u0646\u0627 \u0627\u0648 \u0633\u06cc\u0645\u064a !!! \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u062f tocilizumab \u062f\u0631\u0645\u0644\u0646\u06d0 \u06a9\u0648\u0645 \u0627\u0693\u062e\u06cc\u0632\u06d0 \u0627\u063a\u06cc\u0632\u06d0 \u0644\u06cc\u062f\u0644\u064a\u061f \u06cc\u0627 \u06a9\u0648\u0645 \u0641\u06cc\u0646\u0648\u067c\u0627\u06cc\u067e\u0648\u0646\u0647 \u0686\u06d0 \u067e\u0647 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0645\u0648\u0696\u06a9\u0627\u0646\u0648 \u06a9\u06d0 \u069a\u0647 \u0634\u0648\u064a \u0646\u062f\u064a\u061f \u0689\u0627\u06a9\u067c\u0631 \u062c\u06cc\u0648\u0627\u0646\u0627 \u0644\u062a\u0646\u0632\u064a \u062a\u0647: \u067e\u0648\u069a\u062a\u0646\u0647: \u0644\u0647 \u067c\u0627\u0645 \u0645\u06cc\u0633\u062a\u06cc\u0644\u064a \u0685\u062e\u0647: \u067e\u0647 \u0685\u0627\u0631\u0648\u06cc\u0648 \u06a9\u06d0 \u062f \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 + \u062a\u0648\u0632\u06cc\u0644\u06cc\u0632\u0648\u0645\u0627\u0628 \u062f\u0631\u0645\u0644\u0646\u0647 \u0685\u0648\u0645\u0631\u0647 \u0648\u062e\u062a \u0648\u0647\u061f
\u0681\u0648\u0627\u0628: <\/strong><\/span>\u0645\u0646\u0646\u0647 \u0633\u0648\u0632\u0627\u0646\u0627. \u0646\u0647\u060c \u0645\u0648\u0696 \u062f tocilizumab \u0647\u06cc\u0685 \u0627\u0693\u062e\u06cc\u0632\u0647 \u0627\u063a\u06cc\u0632\u0647 \u0648\u0646\u0647 \u0644\u06cc\u062f\u0644\u0647. \u062f \u0645\u0639\u0627\u06cc\u0646\u0647 \u0634\u0648\u064a \u0641\u06cc\u0646\u0648\u067c\u0627\u06cc\u067e\u0648\u0646\u0648 \u067e\u0647 \u0645\u06cc\u0646\u0681 \u06a9\u06d0 (\u06a9\u0627\u06cc\u0641\u0648\u0633\u060c \u062f \u0627\u0689\u06cc\u067e\u0648\u0632 \u0646\u0633\u062c \u0689\u06cc\u0633\u067c\u0631\u0648\u0641\u064a\u060c \u062f \u0648\u06cc\u069a\u062a\u0648 \u0627\u0648 \u067e\u0648\u0633\u062a\u06a9\u064a \u0646\u06cc\u0645\u06ab\u0693\u062a\u06cc\u0627\u0648\u06d0\u060c \u062f \u0644\u0648\u06a9\u0648\u0645\u0648\u067c\u0631 \u0641\u0639\u0627\u0644\u06cc\u062a\u060c \u062f \u0627\u0648\u0631\u067c\u0627 \u0632\u062e\u0645\u0648\u0646\u0647 \u0627\u0648 \u062f \u0645\u0627\u06cc\u0648\u06a9\u0627\u0631\u0689\u06cc\u0645 \u0647\u0627\u06cc\u067e\u0631\u067c\u0631\u0648\u0641\u064a) \u0681\u0646\u0689\u0648\u0644 \u0634\u0648\u064a \/ \u069a\u0647 \u0634\u0648\u064a.<\/p>\n

\u062a\u0628\u0635\u0631\u0647: <\/strong><\/span>\u062f MARIE GERHARD-HERMAN \u0685\u062e\u0647: \u067e\u0647 \u0645\u062a\u062d\u062f\u0647 \u0627\u06cc\u0627\u0644\u0627\u062a\u0648 \u06a9\u06d0 \u062f \u0631\u0648\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc\u0633\u062a \u0646\u0627\u0631\u0648\u063a\u06cd \u0627\u0648 vasculitis \u0644\u067e\u0627\u0631\u0647 \u0647\u0645 \u06a9\u0627\u0631\u0648\u0644 \u06a9\u06cc\u0696\u064a
\u0681\u0648\u0627\u0628:<\/span> <\/strong>\u062f vasculitis \u0644\u067e\u0627\u0631\u0647 \u062f \u06a9\u0627\u0631\u0648\u0646\u06d0 \u067e\u0647 \u0627\u0693\u0647 \u062f \u062f\u06d0 \u067e\u0647 \u0632\u0693\u0647 \u067e\u0648\u0631\u06d0 \u0645\u0639\u0644\u0648\u0645\u0627\u062a\u0648 \u0644\u067e\u0627\u0631\u0647 \u0644\u0647 \u0645\u0627\u0631\u064a \u0685\u062e\u0647 \u0645\u0646\u0646\u0647.<\/p>\n

\u062a\u0628\u0635\u0631\u0647:<\/span> <\/strong>\u062f \u067e\u06cc \u0633\u06cc \u0633\u067c\u06cc\u0641\u0627\u0646\u0648 \u0685\u062e\u0647: \u062a\u0648\u0633\u06cc\u0644\u06cc\u0632\u0648\u0645\u0627\u0628 \u067e\u0647 \u062c\u0627\u067e\u0627\u0646 \u06a9\u06d0 \u062f \u06a9\u06cc\u0633\u0644 \u0645\u06cc\u0646 \u0646\u0627\u0631\u0648\u063a\u06cd \u062f\u0631\u0645\u0644\u0646\u06d0 \u0644\u067e\u0627\u0631\u0647 \u0647\u0645 \u062a\u0635\u0648\u06cc\u0628 \u0634\u0648\u06cc \u0686\u06d0 \u0647\u06cc\u0685 \u0645\u0639\u0627\u0641\u06cc\u062a\u064a \u0627\u063a\u06cc\u0632\u06d0 \u0646\u0644\u0631\u064a
\u0681\u0648\u0627\u0628: <\/strong><\/span>\u062f \u062f\u06d0 \u0645\u0639\u0644\u0648\u0645\u0627\u062a\u0648 \u0644\u067e\u0627\u0631\u0647 \u0633\u067c\u06cc\u0641\u0627\u0646\u0648 \u0645\u0646\u0646\u0647.<\/p>\n

[\/et_pb_toggle][et_pb_toggle title="\u0689\u0627\u06a9\u067c\u0631 \u0645\u0646\u062c\u0648 \u06a9\u06cc\u0645 \u0627\u0648 \u0633\u0648\u0645\u064a \u06a9\u0627\u0646\u06ab \u062a\u0647 \u0686\u06d0 \u062f \u0689\u0627\u06a9\u067c\u0631 \u0628\u0648\u0645 \u062c\u0648\u0646 \u067e\u0627\u0631\u06a9 \u067e\u0647 \u0627\u0633\u062a\u0627\u0632\u06cc\u062a\u0648\u0628 \u06cc\u06d0 \u0648\u0693\u0627\u0646\u062f\u06d0 \u06a9\u0693\u0647: \u062f \u0689\u0627\u06a9\u067c\u0631 \u0645\u0646\u062c\u0648 \u06a9\u06cc\u0645 \u0627\u0648 \u0633\u0648\u0645\u064a \u06a9\u0627\u0646\u06ab \u0644\u067e\u0627\u0631\u0647 \u06f8 \u067e\u0648\u069a\u062a\u0646\u06d0 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0647 \u0644\u0627\u0646\u062f\u06d0 \u0644\u06cc\u0633\u062a \u0634\u0648\u064a \u062f\u064a." open_toggle_background_color="#f7f7f7" closed_toggle_text_color="#ffffff" closed_toggle_background_color="#00b2e2" icon_color="#ffc15e" open_icon_color="#ffc15e" admin_label="\u06a9\u06cc\u0645 \u0627\u0648 \u06a9\u0627\u0646\u06ab \u067e\u0648\u069a\u062a\u0646\u06d0 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0647 \u06f6 \u067e\u0648\u069a\u062a\u0646\u06d0" _builder_version="4.16" _module_preset="default" title_text_color="#00b2e2" title_font="||||||" \u062f \u0634\u0627\u0644\u064a\u062f_\u0631\u0646\u06ab="#ffffff" \u062f\u0648\u062f\u06cc\u0632_\u062d\u0627\u0635\u0644="||25px" \u062f\u0648\u062f\u06cc\u0632_\u067e\u0689\u06cc\u0646\u06ab="|50px||50px||\u0631\u06cc\u069a\u062a\u06cc\u0627" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u06cd_\u067c\u0648\u0644="0px" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0645\u0639\u0644\u0648\u0645\u0627\u062a="{}"]<\/p>\n

\"\"\"\" <\/strong><\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647:<\/span> <\/strong>\u062f \u0689\u06cc\u0644\u0641\u06cc\u0646 \u0644\u0627\u0631\u06cc\u06cc\u0648 \u0685\u062e\u0647: \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u06ab\u0648\u0631\u0626 \u0686\u06d0 \u062f HGPS \u062d\u062c\u0631\u0648 \/ HGPS \u0645\u0648\u0696\u06a9 \u0645\u0627\u0689\u0644\u0648\u0646\u0648 \u06a9\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u062f\u0631\u0645\u0644\u0646\u06d0 \u0633\u0631\u0647 \u062f DNA \u06a9\u0648\u0645 \u0632\u06cc\u0627\u0646 \u06a9\u0645 \u0634\u0648\u06cc\u061f
\u0681\u0648\u0627\u0628: <\/strong><\/span>\u0645\u0648\u0696 \u0648\u0644\u06cc\u062f\u0644 \u0686\u06d0 \u062f DNA \u062a\u0631\u0645\u06cc\u0645 \u0627\u0693\u0648\u0646\u062f \u062c\u06cc\u0646\u0648\u0646\u0647 (BRCA1, Rad51, etc) \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u0633\u0631\u0647 \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u0648\u0631\u0648\u0633\u062a\u0647 \u0628\u062f\u0644 \u0634\u0648\u064a.<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647:<\/strong> <\/span>\u062f \u0689\u06cc\u0644\u0641\u06cc\u0646 \u0644\u0627\u0631\u0631\u06cc\u0648 \u0685\u062e\u0647: \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u067e\u0647 \u0648\u0631\u0646\u0631 \u06a9\u06d0 \u0685\u0646\u06ab\u0647 \u06a9\u0627\u0631 \u06a9\u0648\u064a
\u0633\u0646\u0689\u0631\u0648\u0645 \u0686\u06d0 - \u062a\u0631 \u0647\u063a\u0647 \u0681\u0627\u06cc\u0647 \u0686\u06d0 \u0632\u0647 \u067e\u0648\u0647\u06cc\u0696\u0645 - \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0646\u0647 \u0685\u0631\u06ab\u0646\u062f\u0648\u064a\u061f \u0627\u06cc\u0627 \u0645\u0627\u0644\u06cc\u06a9\u0648\u0644 \u06a9\u0648\u0645 \u0628\u0644 \u0647\u062f\u0641 \u0644\u0631\u064a\u061f
\u0681\u0648\u0627\u0628: <\/strong><\/span>\u062f WS \u062d\u062c\u0631\u06d0 \u0647\u0645 \u06a9\u0648\u0644\u06cc \u0634\u064a \u062f \u0646\u0648\u0631\u0645\u0627\u0644 \u0639\u0645\u0631 \u067e\u0647 \u0685\u06cc\u0631 \u0644\u0696 \u0645\u0642\u062f\u0627\u0631 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u062a\u0648\u0644\u06cc\u062f \u06a9\u0693\u064a
\u062d\u062c\u0631\u06d0 \u0645\u0648\u0696 \u062f MRNA \u067e\u0647 \u06a9\u0686\u0647 \u062f WS \u062d\u062c\u0631\u0648 \u06a9\u06d0 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0685\u0631\u06ab\u0646\u062f\u0648\u0646\u0647 \u0648\u0644\u06cc\u062f\u0644.
\u0645\u0648\u0696 \u0641\u06a9\u0631 \u06a9\u0648\u0648 \u0686\u06d0 \u062f WRN \u067e\u0631\u0648\u067c\u06cc\u0646 \u06a9\u0648\u0644\u06cc \u0634\u064a \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0645\u062e\u0646\u06cc\u0648\u064a \u0644\u067e\u0627\u0631\u0647 \u06a9\u0627\u0631 \u0648\u06a9\u0693\u064a. \u067e\u0647 \u0647\u0631\u0635\u0648\u0631\u062a\u060c \u067e\u0647
\u062f WS \u0646\u0627\u0631\u0648\u063a\u0627\u0646\u0648 \u0642\u0636\u06cc\u0647\u060c \u0681\u06a9\u0647 \u0686\u06d0 \u062f WRN \u067e\u0631\u0648\u067c\u06cc\u0646 \u0634\u062a\u0648\u0646 \u0646\u0644\u0631\u064a\u060c \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0628\u06cc\u0627\u0646 \u062f\u06cc
\u0641\u06a9\u0631 \u06a9\u06cc\u0696\u064a \u0686\u06d0 \u067e\u0647 20s \u0627\u0648 30s \u06a9\u06d0 \u0648\u0627\u0642\u0639 \u06a9\u06cc\u0696\u064a\u060c \u0685\u0648\u0645\u0631\u0647 \u0686\u06d0 \u062f\u0627 \u067e\u0647 \u0646\u0648\u0631\u0645\u0627\u0644 \u0639\u0645\u0631 \u06a9\u06d0 \u0644\u06cc\u062f\u0644 \u06a9\u06cc\u0696\u064a
\u062e\u0644\u06a9<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: <\/strong><\/span>\u062f \u0628\u0627\u0628 \u0628\u0634\u067e \u0685\u062e\u0647: \u0627\u06cc\u0627 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u067e\u0627\u0628\u0646\u062f \u0633\u0627\u06cc\u067c \u062f \u0628\u0627\u06cc\u0648 \u06a9\u06cc\u0645\u06cc\u06a9\u0644 \u062a\u0639\u0631\u06cc\u0641 \u0634\u0648\u06cc \u06cc\u0627\u061f
\u0633\u0627\u062e\u062a\u0645\u0627\u0646\u064a\u061f \u0627\u06cc\u0627 \u062f \u0627\u0636\u0627\u0641\u064a \u0645\u0631\u06a9\u0628\u0648\u0646\u0648 \u0645\u0648\u0646\u062f\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u0628\u0627\u06cc\u0648 \u06a9\u06cc\u0645\u06cc\u06a9\u0644 \u0627\u0631\u0632\u0648\u0646\u0647 \u0634\u062a\u0648\u0646 \u0644\u0631\u064a
\u062f \u062f\u06d0 \u0645\u06cc\u06a9\u0627\u0646\u06cc\u0632\u0645 \u0633\u0631\u0647\u061f
\u0681\u0648\u0627\u0628: <\/strong><\/span>\u0645\u0648\u0696 \u062f \u0628\u0627\u06cc\u0648\u067c\u06cc\u0646 - \u0627\u06cc\u0648\u0689\u06cc\u0646 \u0645\u0627\u0644\u0627 \u067e\u0644-\u0689\u0627\u0648\u0646 \u0627\u0631\u0632\u0648\u0646\u0647 \u062a\u0631\u0633\u0631\u0647 \u06a9\u0693\u0647 \u0627\u0648 \u0645\u0634\u0627\u0647\u062f\u0647 \u06cc\u06d0 \u06a9\u0693\u0647
\u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0633\u0631\u0647 \u062f \u067e\u06cc\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u0681\u0627\u0646\u06ab\u0693\u064a \u062a\u0639\u0627\u0645\u0644 \u0645\u06ab\u0631 \u062f \u0644\u0627\u0645\u06cc\u0646 A \u060c \u0644\u0627\u0645\u06cc\u0646 \u0633\u0631\u0647 \u0646\u0647
\u0628\u060c p53\u060c \u06cc\u0627 \u0627\u06cc\u0645\u0631\u06cc\u0646.
\u0645\u0648\u0696 \u062f \u0627\u0644\u06cc\u0633\u0627 \u0627\u0631\u0632\u0648\u0646\u0647 \u0647\u0645 \u062a\u0631\u0633\u0631\u0647 \u06a9\u0693\u0647 \u062a\u0631\u0685\u0648 \u0627\u0636\u0627\u0641\u064a \u0645\u0631\u06a9\u0628\u0627\u062a \u0648\u0645\u0648\u0645\u0626 \u06a9\u0648\u0645 \u0686\u06d0 \u06a9\u0648\u0644\u06cc \u0634\u064a
\u062f \u067e\u0648\u067c\u06cc\u067c\u06cc\u0648 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\/\u0644\u0627\u0645\u06cc\u0646 A- \u067e\u0627\u0628\u0646\u062f\u06cd \u0645\u062e\u0646\u06cc\u0648\u06cc \u06a9\u0648\u0646\u06a9\u064a \u0648\u064a. \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0628\u06cc\u0627 \u062a\u0631\u06a9\u06cc\u0628 \u067e\u0631\u0648\u067c\u06cc\u0646 \u067e\u0647 \u062a\u0631\u062a\u06cc\u0628 \u0633\u0631\u0647 \u062f \u06a9\u06cc\u0645\u06cc\u0627\u0648\u064a \u06a9\u062a\u0627\u0628\u062a\u0648\u0646 \u0627\u0648 \u0644\u0627\u0645\u06cc\u0646 A \u0633\u0631\u0647 \u0645\u06cc\u0646\u0681\u0644 \u0634\u0648\u06cc \u0648.
\u067e\u0647 \u0647\u0631\u0635\u0648\u0631\u062a\u060c \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u067e\u0647 \u06a9\u06cc\u0645\u06cc\u0627\u0648\u064a \u06a9\u06d0 \u062a\u0631\u067c\u0648\u0644\u0648 \u0627\u063a\u06cc\u0632\u0645\u0646\u0647 \u06a9\u06cc\u0645\u06cc\u0627\u0648\u064a \u0648\u0647
\u06a9\u062a\u0627\u0628\u062a\u0648\u0646\"\"<\/p>\n

\"\"<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: <\/strong><\/span>\u062f \u062c\u0627\u0646 \u06a9\u0648\u06a9 \u0685\u062e\u0647: \u0644\u0648\u06cc \u067e\u0631\u0645\u062e\u062a\u06ab \u0689\u0627\u06a9\u067c\u0631 \u06a9\u06cc\u0645. \u0627\u06cc\u0627 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u06a9\u0645\u0648\u064a\u061f
\u062f SASP cytokines \u0633\u0631\u0627\u06cc\u062a\u061f
\u0681\u0648\u0627\u0628: <\/strong><\/span>\u0645\u0648\u0696 \u0648\u0644\u06cc\u062f\u0644 \u0686\u06d0 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u06a9\u0648\u0644\u06cc \u0634\u064a \u062f IL6 \u0627\u0648 IL8 \u0628\u06cc\u0627\u0646 \u06a9\u0645 \u06a9\u0693\u064a
HGPS \u062d\u062c\u0631\u06d0.<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: <\/strong><\/span>\u062f \u0633\u0648\u0633\u0646 \u0645\u0627\u06cc\u06a9\u0644\u06cc\u0633 \u0685\u062e\u0647: \u0627\u06cc\u0627 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u062f \u0685\u06cc\u0693\u0648\u0646\u06a9\u0648 \u0644\u067e\u0627\u0631\u0647 \u0634\u062a\u0648\u0646 \u0644\u0631\u064a\u061f
\u0681\u0648\u0627\u0628: <\/strong><\/span>\u0627\u0644\u0628\u062a\u0647\u060c \u062f\u0627 \u0634\u062a\u0648\u0646 \u0644\u0631\u064a \u06a9\u0647 \u062a\u0627\u0633\u0648 \u063a\u0648\u069a\u062a\u0646\u0647 \u0648\u06a9\u0693\u0626.<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: <\/strong><\/span>\u062f \u062a\u0648\u0645\u0627\u0633 \u0689\u0628\u0644\u06cc\u0648 \u06ab\u0644\u0648\u0631 \u0685\u062e\u0647: \u0645\u0627 \u0634\u0627\u06cc\u062f \u062f\u0627 \u0644\u0647 \u0644\u0627\u0633\u0647 \u0648\u0631\u06a9\u0693\u06cc \u0648\u064a \u0645\u06ab\u0631 \u062a\u0627\u0633\u0648 \u0685\u0647 \u0641\u06a9\u0631 \u06a9\u0648\u0626 \u062f\u0627 \u062f\u06cc
\u0647\u063a\u0647 \u0645\u06cc\u06a9\u0627\u0646\u06cc\u0632\u0645 \u0686\u06d0 \u067e\u0647 \u0648\u0631\u0646\u0631 \u0633\u0646\u0689\u0631\u0648\u0645 \u06a9\u06d0 \u062f \u06ab\u067c\u0648\u0631\u0648 \u0627\u063a\u06cc\u0632\u0648 \u0644\u067e\u0627\u0631\u0647 \u0645\u0633\u0624\u0644 \u062f\u06cc\u061f
\u0681\u0648\u0627\u0628: <\/strong><\/span>\u062f WS \u0646\u0627\u0631\u0648\u063a\u0627\u0646\u0648 \u0685\u062e\u0647 \u062a\u0631\u0644\u0627\u0633\u0647 \u0634\u0648\u064a \u062d\u062c\u0631\u06d0 \u0647\u0645 \u0644\u0696 \u0645\u0642\u062f\u0627\u0631 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u062a\u0648\u0644\u06cc\u062f\u0648\u064a \u060c \u0644\u06a9\u0647
\u062f \u0639\u0627\u062f\u064a \u062d\u062c\u0631\u0648 \u067e\u0647 \u0685\u06cc\u0631 \u0686\u06d0 \u062f \u0639\u0645\u0631 \u0644\u0631\u0648\u0646\u06a9\u064a \u062e\u0644\u06a9\u0648 \u0685\u062e\u0647 \u0627\u062e\u06cc\u0633\u062a\u0644 \u06a9\u06cc\u0696\u064a. \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646\u06cc\u0646 \u0647\u0645 \u06a9\u06cc\u062f\u06cc \u0634\u064a
\u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0628\u06cc\u0627\u0646 \u06a9\u0645\u0648\u0644\u0648 \u0633\u0631\u0647 \u062f WS \u062d\u062c\u0631\u0648 \u06a9\u06d0 \u0645\u0624\u062b\u0631\u0647.<\/p>\n

[\/et_pb_toggle][et_pb_toggle title="\u0689\u0627\u06a9\u067c\u0631 \u0645\u0627\u0631\u067c\u06cc\u0646 \u0628\u0631\u06ab\u0648 \u062a\u0647: \u067e\u0648\u069a\u062a\u0646\u0647: \u062f \u0645\u0627\u0631\u06cc\u0648 \u0689\u064a \u06a9\u0648\u0631\u0689\u06cc\u0631\u0648 \u0685\u062e\u0647: \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u062f \u0627\u0644\u062a\u0647\u0627\u0628 \u067e\u0647 \u0627\u0693\u0647 \u0627\u063a\u06cc\u0632 \u0645\u0637\u0627\u0644\u0639\u0647 \u06a9\u0693\u06cc \u062f\u06cc\u061f" open_toggle_background_color="#f7f7f7" closed_toggle_text_color="#ffffff" closed_toggle_background_color="#00b2e2" icon_color="#ffc15e" open_icon_color="#ffc15e" admin_label="\u0689\u0627\u06a9\u067c\u0631 \u0645\u0627\u0631\u067c\u06cc\u0646 \u0628\u0631\u06ab\u0648" _builder_version="4.16" _module_preset="default" title_text_color="#00b2e2" title_font="||||||" \u062f \u0634\u0627\u0644\u064a\u062f_\u0631\u0646\u06ab="#ffffff" \u062f\u0648\u062f\u06cc\u0632_\u062d\u0627\u0635\u0644="||25px" \u062f\u0648\u062f\u06cc\u0632_\u067e\u0689\u06cc\u0646\u06ab="|50px||50px||\u0631\u06cc\u069a\u062a\u06cc\u0627" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u06cd_\u067c\u0648\u0644="0px" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0645\u0639\u0644\u0648\u0645\u0627\u062a="{}"]<\/p>\n

\"\"\u0681\u0648\u0627\u0628: <\/strong>\u062f \u067e\u0648\u069a\u062a\u0646\u06d0 \u0644\u067e\u0627\u0631\u0647 \u0645\u0646\u0646\u0647: \u0646\u0647\u060c \u067e\u0647 \u0647\u0631\u0647 \u0628\u0631\u062e\u0647 \u06a9\u06d0 \u0633\u0648\u0632\u0634 \u0646\u0647. \u067e\u0647 \u062c\u0632\u0648\u064a \u062a\u0648\u06ab\u0647 \u062f \u0627\u0644\u062a\u0647\u0627\u0628 \u067e\u0648\u0631\u06d0 \u0627\u0693\u0648\u0646\u062f\u060c \u0645\u0648\u0696 \u067e\u0647 \u062f\u06d0 \u067e\u0631\u0648\u0698\u0647 \u06a9\u06d0 \u0645\u06cc\u06a9\u0631\u0648\u0641\u06cc\u062c\u0648\u0646\u0647 \u0645\u0637\u0627\u0644\u0639\u0647 \u06a9\u0693\u064a \u0627\u0648 \u0645\u0648\u0646\u062f\u0644\u064a \u0686\u06d0\u00a0Icmt<\/i>\u00a0\u062f \u0645\u06cc\u06a9\u0631\u0648\u0641\u06cc\u062c \u06a9\u0648\u0644\u06cc\u0633\u067c\u0631\u0648\u0644 \u062c\u0631\u06cc\u0627\u0646 \u0632\u06cc\u0627\u062a\u0648\u064a\u060c \u062f\u0648\u0627\u0693\u0647 \u0628\u06cc\u0633\u0627\u0644 \u0627\u0648 ApoAI- \u0627\u0648 HDL- \u0645\u062d\u0631\u06a9. \u0644\u06a9\u0647 \u0685\u0646\u06ab\u0647 \u0686\u06d0 \u062f\u0627 \u0627\u063a\u06cc\u0632\u0647 \u06a9\u0644\u0647 \u0646\u0627\u06a9\u0644\u0647 \u067e\u0647 \u0648\u06cc\u0648\u0648 \u06a9\u06d0 \u062f \u0628\u0631\u0639\u06a9\u0633 \u06a9\u0648\u0644\u06cc\u0633\u067c\u0631\u0648\u0644 \u067c\u0631\u0627\u0646\u0633\u067e\u0648\u0631\u067c \u0633\u0631\u0647 \u062a\u0693\u0627\u0648 \u0644\u0631\u064a\u060c \u0645\u0648\u0696 \u063a\u0648\u0627\u0693\u0648 \u0645\u0639\u0644\u0648\u0645\u0647 \u06a9\u0693\u0648 \u0686\u06d0 \u0622\u06cc\u0627\u00a0Icmt<\/i>\u00a0\u0645\u062e\u0646\u06cc\u0648\u06cc \u0628\u0647 \u062f \u0627\u06cc\u062a\u0631\u0648\u0633\u06a9\u0644\u0631\u0648\u0633\u06cc\u0633 \u0648\u062f\u0647 \u06a9\u0645\u0647 \u06a9\u0693\u064a.<\/p>\n

[\/et_pb_toggle][et_pb_toggle title="\u0689\u0627\u06a9\u067c\u0631 \u0689\u06cc\u0648\u06cc\u0689 \u0644\u06cc\u0648 \u062a\u0647: \u067e\u0648\u069a\u062a\u0646\u0647: \u062f \u0689\u0627\u06a9\u067c\u0631 \u0644\u0648\u064a \u0644\u067e\u0627\u0631\u0647 3 \u067e\u0648\u069a\u062a\u0646\u06d0 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0647 \u0644\u0627\u0646\u062f\u06d0 \u0644\u06cc\u0633\u062a \u0634\u0648\u064a \u062f\u064a." open_toggle_background_color="#f7f7f7" closed_toggle_text_color="#ffffff" closed_toggle_background_color="#00b2e2" icon_color="#ffc15e" open_icon_color="#ffc15e" admin_label="\u0689\u0627\u06a9\u067c\u0631 \u0689\u06cc\u0648\u06cc\u0689 \u0644\u06cc\u0648 \u067e\u0648\u069a\u062a\u0646\u0647 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0647 3\u2033 _builder_version="4.16" _module_preset="default" title_text_color="#00b2e2" title_font="||||||" \u062f \u0634\u0627\u0644\u064a\u062f_\u0631\u0646\u06ab="#ffffff" \u062f\u0648\u062f\u06cc\u0632_\u062d\u0627\u0635\u0644="||25px" \u062f\u0648\u062f\u06cc\u0632_\u067e\u0689\u06cc\u0646\u06ab="|50px||50px||\u0631\u06cc\u069a\u062a\u06cc\u0627" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u06cd_\u067c\u0648\u0644="0px" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0645\u0639\u0644\u0648\u0645\u0627\u062a="{}"]<\/p>\n

\"\"<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: <\/strong><\/span>\u062f \u0648\u06cc\u0646\u0689\u0631\u06cc\u0633 \u0685\u062e\u0647: \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u062f \u0645\u062e\u062a\u0644\u0641 \u0639\u0645\u0631\u0648\u0646\u0648 (\u067e\u0647 \u0648\u06cc\u067c\u0631\u0648 \u06a9\u06d0) \u062f \u0627\u0646\u0633\u0627\u0646 HGPS \u0641\u0627\u06cc\u0628\u0631\u0648\u0628\u0644\u0627\u0633\u062a\u0648\u0646\u0648 \u06a9\u06d0 \u062f DNA \u0627\u0635\u0644\u0627\u062d \u0647\u0685\u0647 \u06a9\u0693\u06d0 \u0627\u0648 \u062f \u062f\u0648\u06cc \u0641\u06cc\u0646\u0648\u067c\u0627\u06cc\u067e \u0646\u0648\u0631\u0645\u0627\u0644 \u06a9\u0648\u0644\u0648 \u0627\u0632\u0645\u0648\u06cc\u0646\u0647 \u06a9\u0693\u06d0 \u062a\u0631\u0685\u0648 \u0648\u06ab\u0648\u0631\u0626 \u0686\u06d0 \u0627\u06cc\u0627 \u062f\u0627 \u062f \u062d\u062c\u0631\u0648 \u0639\u0645\u0631 \u0633\u0631\u0647 \u06a9\u0645\u06cc\u0696\u064a\u061f
\u0681\u0648\u0627\u0628:<\/span> <\/strong>\u0646\u0647\u060c \u0645\u0648\u0696 \u062f \u0689\u06cc\u0631\u06cc \u0645\u062e\u062a\u0644\u0641 \u0639\u0645\u0631\u0648\u0646\u0648 \u0646\u0627\u0631\u0648\u063a\u0627\u0646\u0648 \u0685\u062e\u0647 \u062f \u0641\u0627\u06cc\u0628\u0631\u0648\u0628\u0644\u0627\u0633\u067c\u0648\u0646\u0648 \u0627\u0635\u0644\u0627\u062d \u06a9\u0648\u0644\u0648 \u0647\u0685\u0647 \u0646\u0647 \u062f\u0647 \u06a9\u0693\u06d0 - \u06cc\u0648\u0627\u0632\u06d0 \u062f \u062f\u0648\u0647 \u0645\u062e\u062a\u0644\u0641 \u0646\u0627\u0631\u0648\u063a\u0627\u0646\u0648 \u0685\u062e\u0647\u060c \u0686\u06d0 \u0648\u0631\u062a\u0647 \u067e\u0627\u06cc\u0644\u06d0 \u06cc\u06d0 \u062a\u0631\u0644\u0627\u0633\u0647 \u06a9\u0693\u06d0.<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647:<\/strong> <\/span>\u062f \u0689\u06cc\u0644\u0641\u06cc\u0646 \u0644\u0627\u0631\u06cc\u0648 \u0685\u062e\u0647: \u067e\u0647 \u0632\u0693\u0647 \u067e\u0648\u0631\u064a \u0627\u063a\u06cc\u0632\u06d0! \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u067e\u0647 \u0647\u06cc\u067c\u0631\u0648\u0632\u06cc\u06ab\u0648\u0633 \u0645\u0648\u0696\u06a9\u0648\u0646\u0648 \u06a9\u06d0 \u062f \u0628\u0634\u067e\u0693 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 KO \u062a\u0645\u0647 \u06a9\u0648\u0626\u061f
\u0681\u0648\u0627\u0628:<\/span> <\/strong>\u067e\u0647 \u0648\u0627\u062d\u062f \u06a9\u0627\u067e\u064a \u0645\u0648\u0696\u06a9 \u06a9\u06d0\u060c \u0632\u0647 \u0628\u0647 \u062f \u0627\u0693\u062a\u06cc\u0627 \u067e\u0647 \u067e\u0631\u062a\u0644\u0647 \u062f \u0647\u063a\u0647 \u0685\u0647 \u067e\u0647 \u067e\u0631\u062a\u0644\u0647 \u0686\u06d0 \u0645\u0648\u0696 \u06cc\u06d0 \u0627\u0648\u0633 \u0645\u0647\u0627\u0644 \u06ab\u0648\u0631\u0648 \u062f \u0689\u06cc\u0631\u06cc \u0645\u062e\u062a\u0644\u0641 \u0627\u06cc\u0689\u06cc\u067c \u06a9\u0648\u0644\u0648 \u0648\u0693\u062a\u06cc\u0627 \u062a\u0645\u0647 \u0646\u0644\u0631\u0645\u060c \u0681\u06a9\u0647 \u0686\u06d0 \u0628\u0627\u06cc\u062f \u062f \u0647\u0631 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0644\u067e\u0627\u0631\u0647 \u062f \u062a\u0631\u0645\u06cc\u0645 \u0627\u062c\u0646\u067c \u0689\u06cc\u0631 \u0648\u064a.<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: <\/span><\/strong>\u062f \u0627\u0646\u062f\u0631\u06d0 \u0645\u0648\u0646\u067c\u06cc\u0631\u0648 \u062f\u0627 \u0631\u0648\u0686\u0627 \u0685\u062e\u0647: \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u0641\u06a9\u0631 \u06a9\u0648\u0626 \u0686\u06d0 \u062f \u067c\u06cc\u067c\u06d0 \u0633\u0644\u0646\u06d0 \u062d\u062c\u0631\u0648 \u0628\u06cc\u0627 \u0628\u0631\u0646\u0627\u0645\u0647 \u06a9\u0648\u0644 \u06a9\u0648\u0644\u06cc \u0634\u064a \u062f \u0633\u067c\u06cc\u0645 \u062d\u062c\u0631\u0648 \u0641\u0639\u0627\u0644\u06cc\u062a \u062a\u0631\u0645\u06cc\u0645 \u06a9\u0693\u064a \u060c \u0645\u06ab\u0631 \u0645\u0645\u06a9\u0646 \u062f \u0644\u0648\u06cc \u0633\u067c\u06cc\u0645 \u062d\u062c\u0631\u0648 \u0633\u062a\u0693\u06cc\u0627 \u0644\u0627\u0645\u0644 \u0634\u064a\u061f
\u0681\u0648\u0627\u0628:<\/span> <\/strong>\u0645\u0648\u0696 \u062f\u0627\u0633\u06d0 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0646\u0644\u0631\u0648 \u0686\u06d0 \u062f\u06d0 \u067e\u0648\u069a\u062a\u0646\u06d0 \u062a\u0647 \u0681\u0648\u0627\u0628 \u0648\u0648\u0627\u06cc\u06cc.<\/p>\n

[\/et_pb_toggle][et_pb_toggle title="\u0689\u0627\u06a9\u067c\u0631 \u06a9\u0648\u0644\u06cc\u0646 \u0633\u067c\u06cc\u0648\u0627\u0631\u067c \u062a\u0647: \u062f \u0689\u0627\u06a9\u067c\u0631 \u0633\u067c\u06cc\u0648\u0627\u0631\u067c \u0644\u067e\u0627\u0631\u0647 \u06f8 \u067e\u0648\u069a\u062a\u0646\u06d0 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0647 \u0644\u0627\u0646\u062f\u06d0 \u0644\u06cc\u0633\u062a \u0634\u0648\u064a \u062f\u064a." open_toggle_background_color="#f7f7f7" closed_toggle_text_color="#ffffff" closed_toggle_background_color="#00b2e2" icon_color="#ffc15e" open_icon_color="#ffc15e" admin_label="\u0689\u0627\u06a9\u067c\u0631 \u06a9\u0648\u0644\u06cc\u0646 \u0633\u067c\u06cc\u0648\u0627\u0631\u067c" _builder_version="4.16" _module_preset="default" title_text_color="#00b2e2" title_font="||||||" \u062f \u0634\u0627\u0644\u064a\u062f_\u0631\u0646\u06ab="#ffffff" \u062f\u0648\u062f\u06cc\u0632_\u062d\u0627\u0635\u0644="||25px" \u062f\u0648\u062f\u06cc\u0632_\u067e\u0689\u06cc\u0646\u06ab="|50px||50px||\u0631\u06cc\u069a\u062a\u06cc\u0627" \u062f \u0633\u0631\u062d\u062f_\u0686\u0648\u06a9\u06cd_\u067c\u0648\u0644="0px" \u0646\u0693\u06cc\u0648\u0627\u0644_\u0631\u0646\u06ab\u0648\u0646\u0647_\u0645\u0639\u0644\u0648\u0645\u0627\u062a="{}"]<\/p>\n

\"\"\u067e\u0648\u069a\u062a\u0646\u0647:<\/strong><\/span> \u062f \u0645\u06cc \u0685\u062e\u0647: \u062f \u06a9\u0627\u0631\u062a\u06cc\u0648 \u0645\u0627\u06cc\u0648\u0633\u06cc\u067c \u067e\u0647 \u0685\u06cc\u0631 \u069a\u06a9\u0627\u0631\u064a\u060c \u069a\u06a9\u0644\u06cc \u062f\u0627\u063a!
\u062f \u0627\u0628\u06cc \u0628\u0648\u0686\u0648\u0627\u0644\u067c\u0631 \u0685\u062e\u0647: \u0622\u06cc\u0627 \u062f Sun1 \u063a\u0627\u0644\u0628 \u0645\u0646\u0641\u064a \u0685\u0631\u06ab\u0646\u062f\u0648\u0646\u0647 \u062f LINC \u067c\u0648\u0644 \u06a9\u0645\u067e\u0644\u06cc\u06a9\u0633\u0648\u0646\u0647 \u06ab\u0689\u0648\u0689\u0648\u064a \u060c \u067e\u0634\u0645\u0648\u0644 \u062f \u0633\u0646 2 \u0644\u062e\u0648\u0627 \u0645\u0646\u0681\u06ab\u0693\u06cc\u062a\u0648\u0628\u061f
\u0681\u0648\u0627\u0628:<\/span> <\/strong>\u0647\u0648 \u067e\u0647 \u0648\u06cc\u067c\u0631\u0648 \u06a9\u06d0 \u062f \u062f\u06d0 \u0644\u067e\u0627\u0631\u0647 \u0634\u0648\u0627\u0647\u062f \u0634\u062a\u0648\u0646 \u0644\u0631\u064a \u0686\u06d0 \u067e\u0647 NE \u06a9\u06d0 \u067c\u0648\u0644 \u0646\u06cc\u0633\u067e\u0631\u06cc\u0646 \u062f DNSUN1 \u0644\u062e\u0648\u0627 \u0628\u06d0 \u0681\u0627\u06cc\u0647 \u06a9\u06cc\u062f\u06cc \u0634\u064a<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647:<\/strong><\/span> \u062f Suet Nee Chen \u0685\u062e\u0647: \u0685\u0646\u06ab\u0647 \u0627\u0648 \u06a9\u0648\u0645 \u0645\u06cc\u06a9\u0627\u0646\u06cc\u0632\u0645 \u062f\u06cc \u0686\u06d0 AAV9-SunDn \u062f \u0627\u0648\u0696\u062f\u06d0 \u0645\u0648\u062f\u06d0 \u0627\u063a\u06cc\u0632\u0648 \u0648\u0693\u062a\u06cc\u0627 \u0644\u0631\u064a\u061f \u062a\u0627\u0633\u0648 \u067e\u0647 \u06a9\u0648\u0645 \u0639\u0645\u0631 \u06a9\u06d0 LMNA \u0645\u062a\u063a\u06cc\u0631 \u0645\u0648\u0696\u06a9\u0627\u0646\u0648 \u062a\u0647 AAV9-Sun1DN \u0627\u0646\u062c\u06cc\u06a9\u0634\u0646 \u06a9\u0693\u06cc\u061f
\u0681\u0648\u0627\u0628:<\/span> <\/strong>\u0645\u0648\u0696 DNSUN1 AAV \u062f \u0644\u0627\u0645\u06cc\u0646\u0627 \u062d\u0630\u0641 \u06a9\u0648\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u062f Cre recombinase \u0647\u0685\u0648\u0644\u0648 \u06cc\u0648\u0647 \u0648\u0631\u0681 \u0648\u0631\u0648\u0633\u062a\u0647 \u0627\u0646\u062c\u06cc\u06a9\u0634\u0646 \u06a9\u0693. \u0645\u0648\u0696 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0644\u0631\u0648 \u0686\u06d0 \u062f AAV \u0644\u062e\u0648\u0627 \u0648\u0631\u06a9\u0693\u0644 \u0634\u0648\u064a DNSUN1 \u062f \u0627\u0646\u062c\u06cc\u06a9\u0634\u0646 \u0685\u062e\u0647 \u06cc\u0648 \u06a9\u0627\u0644 \u0648\u0631\u0648\u0633\u062a\u0647 \u062f \u06a9\u0627\u0631\u062a\u06cc\u0648 \u0645\u0627\u06cc\u0648\u0633\u0627\u06cc\u067c\u0633 \u0685\u0631\u06ab\u0646\u062f\u0648\u0644\u0648 \u062a\u0647 \u062f\u0648\u0627\u0645 \u0648\u0631\u06a9\u0648\u064a. \u0645\u0648\u0696 \u0627\u0648\u0633 \u062f \u062e\u0648\u0631\u0627\u06a9 \/ \u0648\u062e\u062a \/ \u063a\u0628\u0631\u06ab\u0648\u0646 \u062a\u062c\u0631\u0628\u06d0 \u062a\u0631\u0633\u0631\u0647 \u06a9\u0648\u0648 \u0686\u06d0 \u0645\u0648\u0696 \u0628\u06cc\u0631\u062a\u0647 \u0644\u0627\u0628\u0631\u0627\u062a\u0648\u0627\u0631 \u06a9\u06d0 \u06cc\u0648 \u0627\u0648 \u06a9\u0648\u0644\u06cc \u0634\u0648 \u062e\u067e\u0644 AAV \u067e\u0647 \u06a9\u0627\u0641\u064a \u0645\u0642\u062f\u0627\u0631 \u06a9\u06d0 \u062c\u0648\u0693 \u06a9\u0693\u0648<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647:<\/span><\/strong> \u062f \u0645\u0627\u0631\u062a\u06cc\u0646 \u0628\u0631\u06ab\u0648 \u0685\u062e\u0647\u060c \u062f \u0644\u06cc\u0633\u0627\u0646\u0633 \u06a9\u0645\u06cc\u067c\u06cc \u0644\u067e\u0627\u0631\u0647: \u062a\u0627\u0633\u0648 \u0685\u0647 \u0641\u06a9\u0631 \u06a9\u0648\u0626 \u0633\u062a\u0627\u0633\u0648 \u062f Lmna \u0646\u0627\u06a9 \u0622\u0648\u067c \u062a\u062c\u0631\u0628\u0648 \u06a9\u06d0 \u062f \u063a\u06cc\u0631 \u062d\u0627\u0636\u0631 \u0644\u0627\u0645\u06cc\u0646 A \u067e\u0647 \u0645\u0642\u0627\u0628\u0644 \u06a9\u06d0 \u062f \u0644\u0627\u0645\u06cc\u0646 C \u0646\u0633\u0628\u064a \u0648\u0646\u0689\u0647 \u0685\u0647 \u062f\u0647\u061f
\u0681\u0648\u0627\u0628:<\/strong><\/span> \u0632\u0647 \u067e\u062f\u06d0 \u0627\u0693\u0647 \u0689\u0627\u0689\u0647 \u0646\u0647 \u06cc\u0645 \u0645\u06ab\u0631 Sun1 \u062f \u0644\u0627\u0645\u06cc\u0646\u0627 \u0633\u0631\u0647 \u0627\u0693\u06cc\u06a9\u0647 \u0644\u0631\u064a \u0627\u0648 \u067e\u0647 HGPS \u0645\u0648\u0696\u06a9\u0648\u0646\u0648 \u06a9\u06d0 \u0648\u0646\u0689\u0647 \u0628\u0627\u06cc\u062f \u067c\u0648\u0644 \u0644\u0627\u0645\u06cc\u0646\u0627 \u0648\u064a (\u0644\u0647 \u06a9\u0648\u0645 \u0681\u0627\u06cc \u0685\u062e\u0647 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0627\u062e\u06cc\u0633\u062a\u0644 \u0634\u0648\u06cc)<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647:<\/span><\/strong> \u062f jcampisi \u0685\u062e\u0647: \u067e\u0647 SUN1 KO \u06cc\u0627 hets \u06a9\u06d0 \u062f \u0645\u0693\u06cc\u0646\u06d0 \u0644\u0627\u0645\u0644 \u0685\u0647 \u062f\u06cc\u061f
\u0681\u0648\u0627\u0628:<\/strong><\/span> \u069a\u0647 \u067e\u0648\u069a\u062a\u0646\u0647 \u0686\u06d0 \u0645\u0648\u0696 \u0644\u0627\u0647\u0645 \u0646\u0647 \u067e\u0648\u0647\u06cc\u0696\u0648 \u0645\u06ab\u0631 \u0627\u0648\u0633 \u0645\u0647\u0627\u0644 \u062f \u06a9\u0646\u06a9\u0627\u0644 \u062f \u0639\u0636\u0644\u0627\u062a\u0648 \u0681\u06cc\u0646\u06d0 \u06ab\u0631\u0648\u067e \u0634\u06a9\u0645\u0646 \u06cc\u0648 \u0645\u0648\u0696 \u062f \u0645\u0693\u0648 \u0645\u0648\u0696\u06a9\u0627\u0646\u0648 \u069a\u0647 \u0647\u0633\u067c\u0648 \u067e\u0627\u067c\u0648 \u062a\u062d\u0644\u06cc\u0644 \u062a\u0647 \u0627\u0693\u062a\u06cc\u0627 \u0644\u0631\u0648.<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: <\/span><\/strong>\u062f \u067c\u0627\u0645 \u0645\u06cc\u0633\u067c\u0644\u064a \u0685\u062e\u0647: \u06a9\u0648\u0644\u0646: \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u067e\u0647 Lmna\/Sun \u062d\u06cc\u0648\u0627\u0646\u0627\u062a\u0648 \u06a9\u06d0 \u062f \u0633\u06cc\u0644\u0648\u0644\u0631 \u0641\u0634\u0627\u0631 \u063a\u0628\u0631\u06ab\u0648\u0646 \u0644\u0627\u0631\u06d0 \u06a9\u06d0 \u0628\u062f\u0644\u0648\u0646\u0648\u0646\u0647 \u0644\u06cc\u062f\u0644\u064a\u061f
\u0681\u0648\u0627\u0628:<\/strong><\/span> \u0645\u0648\u0696 \u062a\u0631\u0627\u0648\u0633\u0647 \u067e\u062f\u06d0 \u0645\u0648\u0696\u06a9\u0627\u0646\u0648 \u06a9\u06d0 \u062f \u0641\u0634\u0627\u0631 \u063a\u0628\u0631\u06ab\u0648\u0646 \u062c\u06cc\u0646\u0648\u0646\u0647 \/ \u0645\u0627\u0631\u06a9\u0631\u0648\u0646\u0647 \u0646\u062f\u064a \u0627\u0646\u062f\u0627\u0632\u0647 \u06a9\u0693\u064a<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647: \u062f \u0689\u06cc\u0644\u0641\u06cc\u0646 \u0644\u0627\u0631\u0631\u06cc\u0648 \u0685\u062e\u0647: \u0627\u06cc\u0627 \u062a\u0627\u0633\u0648 \u0628\u0647 \u062f HGPS \u0646\u0627\u0631\u0648\u063a\u0627\u0646\u0648 \u06a9\u06d0 \u062f DNSUN1 \u0633\u0631\u0647 \u06cc\u0648\u0627\u0632\u06d0 \u0632\u0693\u0647 \u067e\u0647 \u0646\u069a\u0647 \u06a9\u0693\u0626\u061f
\u0681\u0648\u0627\u0628:<\/strong><\/span> \u062f\u0627 \u062f \u0633\u06cc\u0631\u0648\u067c\u0627\u06cc\u067e \u0627\u0648 \u062f \u06a9\u0627\u0631\u062f\u06cc\u0648 \u0645\u0627\u06cc\u0648\u0633\u0627\u06cc\u067c \u0681\u0627\u0646\u06ab\u0693\u064a \u067e\u0631\u0648\u0645\u0648\u067c\u0631 \u06a9\u0627\u0631\u0648\u0644\u0648 \u0633\u0631\u0647 \u0645\u0645\u06a9\u0646\u0647 \u062f\u0647. \u062f\u0627 \u062a\u062c\u0631\u0628\u06d0 \u0627\u0648\u0633 \u062f \u067e\u0631\u0645\u062e\u062a\u06ab \u067e\u0647 \u062d\u0627\u0644 \u06a9\u06d0 \u062f\u064a<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647:<\/span><\/strong>\u062f \u06cc\u0648\u06a9\u0633\u06cc\u0627 \u0648\u0627\u0646\u06ab \u0685\u062e\u0647: \u0648\u0644\u06d0 KO SUN1 \u067e\u0647 \u0647\u0648\u0645\u0648\u0632\u0627\u06cc\u06ab\u0633 G609G \u0645\u0648\u0696\u06a9\u0627\u0646\u0648 \u06a9\u06d0 \u0644\u0696 \u06ab\u067c\u0647 \u0644\u0631\u064a\u061f
\u0681\u0648\u0627\u0628:<\/strong><\/span> \u0627\u062d\u062a\u0645\u0627\u0644 \u0644\u0631\u064a \u0681\u06a9\u0647 \u0686\u06d0 \u0647\u0648\u0645\u0648\u0632\u0627\u06cc\u06ab\u0648\u0633 \u0645\u0648\u0696\u06a9\u0627\u0646 \u0689\u06cc\u0631 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0685\u0631\u06ab\u0646\u062f\u0648\u064a. \u0645\u0648\u0696 \u067e\u0647 \u062e\u067e\u0644\u0648 \u062c\u0646\u06cc\u067c\u06cc\u06a9 \u062a\u062c\u0631\u0628\u0648 \u06a9\u06d0 \u062f \u0647\u06cc\u067c\u0631\u0648\u0632\u06cc\u06ab\u0648\u067c\u0633 v homozygotes \u063a\u0628\u0631\u06ab\u0648\u0646 \u0627\u063a\u06cc\u0632 \u06ab\u0648\u0631\u0648<\/p>\n

\u067e\u0648\u069a\u062a\u0646\u0647:<\/span><\/strong>\u062f \u0631\u0648\u0644\u0627\u0646\u0689 \u0641\u0648\u0633\u0646\u0631 \u0685\u062e\u0647: \u0633\u0644\u0627\u0645 \u06a9\u0648\u0644\u0646\u060c \u069a\u0647 \u062e\u0628\u0631\u06d0. \u067e\u0647 HGPS \u06a9\u06d0 \u062f \u067e\u0648\u0631\u062a\u0647 \u0634\u0648\u064a SUN1 \u0645\u0646\u0641\u064a \u0627\u063a\u06cc\u0632\u0647 \u0685\u0647 \u062f\u0647\u061f \u0631\u0648\u0644\u0627\u0646\u062f
\u0681\u0648\u0627\u0628:<\/strong><\/span> \u069a\u0627\u06cc\u064a \u062f LINC \u06a9\u0645\u067e\u0644\u06cc\u06a9\u0633 \u0633\u0631\u0647 \u062f MT \u0634\u0628\u06a9\u06d0 \u0627\u0693\u06cc\u06a9\u06d0 \u0632\u06cc\u0627\u062a\u06d0 \u0634\u064a. \u062f \u06a9\u0644\u062a\u0648\u0631 \u067e\u0647 \u062d\u062c\u0631\u0648 \u06a9\u06d0 \u062f \u0644\u0645\u0631 \/ \u0646\u06cc\u0633\u067e\u0631\u06cc\u0646 \u0685\u0631\u06ab\u0646\u062f\u0648\u0646\u0647 \u0632\u06cc\u0627\u062a\u0648\u0627\u0644\u06cc \u0627\u067c\u0648\u0645\u064a \u0645\u0648\u0642\u0639\u06cc\u062a \u0627\u0648 \u062f \u062d\u062c\u0631\u0648 \u0645\u0647\u0627\u062c\u0631\u062a \u0627\u063a\u06cc\u0632\u0647 \u06a9\u0648\u064a<\/p>\n

[\/et_pb_toggle][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/07\/Basso.Peraut-Family.jpg\u201d title_text=\u201dBasso.Peraut-Family\u201d align=\u201dcenter\u201d admin_label=\u201dfamilies\u201d _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d custom_margin=\u201d5px||15px||false|false\u201d global_colors_info=\u201d{}\u201d][\/et_pb_image][et_pb_toggle title=\u201d\u062f \u0686\u06cc\u0679 \u062a\u0628\u0635\u0631\u0648 \u0685\u062e\u0647 \u06cc\u0648\u0647 \u0646\u0645\u0648\u0646\u0647 \u0627\u062e\u06cc\u0633\u062a\u0644!\u201d open_toggle_background_color=\u201d#f7f7f7\u2033 closed_toggle_text_color=\u201d#ffffff\u201d closed_toggle_background_color=\u201d#00b2e2\u2033 icon_color=\u201d#ffc15e\u201d open_icon_color=\u201d#ffc15e\u201d admin_label=\u201d\u062f \u0686\u06cc\u0679 \u062a\u0628\u0635\u0631\u0648 \u0685\u062e\u0647 \u0646\u0645\u0648\u0646\u0647 \u0627\u062e\u06cc\u0633\u062a\u0644!\u201d _builder_version=\u201d4.16\u2033 _module_preset=\u201ddefault\u201d title_text_color=\u201d#00b2e2\u2033 title_font=\u201d||||||\u201d background_color=\u201d#ffffff\u201d custom_margin=\u201d||25px\u201d custom_padding=\u201d|50px||50px||true\u201d border_width_all=\u201d0px\u201d global_colors_info=\u201d{}\u201d]<\/p>\n

\u062f \u0628\u0627\u0633\u0648 \u0627\u0648 \u067e\u06cc\u0631\u0648\u067c \u06a9\u0648\u0631\u0646\u06cd \u0633\u0631\u0647 \u0644\u06cc\u062f\u0648 \u0644\u067e\u0627\u0631\u0647 \u0648\u06cc\u0627\u0693. \u0633\u062a\u0627\u0633\u0648 \u062f \u0633\u0641\u0631 \u0634\u0631\u06cc\u06a9\u0648\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u0645\u0646\u0646\u0647. \u062a\u0627\u0633\u0648 \u0648\u0627\u0642\u0639\u06cc\u0627 \u0627\u0648 \u0627\u0644\u0647\u0627\u0645 \u06cc\u0627\u0633\u062a!<\/p>\n

\u062f \u0633\u0645\u06cc\u0639 \u0627\u0648 \u0627\u0644\u06cc\u06ab\u0632\u0627\u0646\u0689\u0631\u0627 \u0644\u0647 \u06a9\u0648\u0631\u0646\u06cd \u0685\u062e\u0647 \u0645\u0646\u0646\u0647 \u0686\u06d0 \u062f \u0648\u0631\u06a9\u0634\u0627\u067e \u0628\u0631\u062e\u0647 \u0627\u0648\u0633\u0626 \u0627\u0648 \u062e\u067e\u0644 \u0627\u0644\u0647\u0627\u0645\u064a \u0633\u0641\u0631 \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0631\u0647 \u0634\u0631\u06cc\u06a9 \u06a9\u0693\u0626!<\/p>\n

\u067e\u0647 \u0627\u0641\u0642 \u06a9\u06d0 \u062f \u062a\u0635\u0648\u06cc\u0628 \u0633\u0631\u0647 \u0627\u06cc\u06ab\u0631 \u067e\u0647 \u0632\u0693\u0647 \u067e\u0648\u0631\u06cc \u067e\u0631\u0645\u062e\u062a\u06ab.<\/p>\n

\u0627\u06cc\u0627 \u0645\u0648\u0696 \u06a9\u0648\u0644\u06cc \u0634\u0648 \u062f\u0627 \u063a\u0648\u0646\u0689\u0647 \u062f \u0627\u0648\u0646\u06cd \u067e\u0627\u06cc \u062a\u0647 \u0648\u063a\u0681\u0648\u0648 \u0627\u0648 \u0628\u062d\u062b \u062a\u0647 \u062f\u0648\u0627\u0645 \u0648\u0631\u06a9\u0693\u0648\u061f (\u0645\u0646\u0646\u0647\u060c \u06cc\u0648 \u0627\u0648 \u067c\u0648\u0644!)\u00a0<\/p>\n

\u062f\u0627 \u0648\u0631\u06a9\u0634\u0627\u067e \u062f \u0646\u0647 \u0645\u0646\u0644\u0648 \u0648\u0693 \u0648. \u0632\u0647 PRF \u062a\u0647 \u062f \u062f\u06d0 \u0633\u062a\u0631 \u0641\u0639\u0627\u0644\u06cc\u062a \u062f \u062a\u0631\u0633\u0631\u0647 \u06a9\u0648\u0644\u0648 \u062f \u0698\u0645\u0646\u062a\u06cc\u0627 \u0644\u0647 \u0627\u0645\u0644\u0647 \u0645\u0628\u0627\u0631\u06a9\u064a \u0648\u0627\u06cc\u0645. \u0628\u06d0 \u0644\u0647 \u0634\u06a9\u0647\u060c \u062f\u06d0 \u0648\u0631\u06a9\u0634\u0627\u067e \u0632\u0645\u0627 \u062f \u0631\u0627\u062a\u0644\u0648\u0646\u06a9\u064a \u0644\u067e\u0627\u0631\u0647 \u062f \u0689\u06cc\u0631\u06cc \u067e\u0648\u0647\u06d0 \u0685\u062e\u0647 \u0689\u06a9 \u06a9\u0693. \u062f\u0627 \u062d\u06cc\u0631\u0627\u0646\u062a\u06cc\u0627 \u0648\u0647. \u067e\u0647 \u06ab\u0689\u0647 \u0628\u0647 \u06cc\u06d0 \u062f\u0631\u0645\u0644\u0646\u0647 \u067e\u06cc\u062f\u0627 \u06a9\u0693\u0648!<\/p>\n

\u062a\u0644 \u062f PRF \u063a\u0648\u0646\u0689\u0648 \u06a9\u06d0 \u067e\u0647 \u0632\u0693\u0647 \u067e\u0648\u0631\u064a \u0633\u0627\u06cc\u0646\u0633 \u0685\u062e\u0647 \u0645\u062a\u0627\u062b\u0631\u0647 \u0634\u0648\u064a. \u062f \u067c\u0648\u0644\u0646\u06d0 \u062f \u0648\u0631\u06a9\u0634\u0627\u067e \u062a\u062c\u0631\u0628\u06d0 \u062d\u062a\u06cc \u067e\u0647 \u062f\u06d0 \u0645\u062c\u0627\u0632\u06cc \u0628\u06bc\u0647 \u06a9\u06d0 \u062f \u0633\u0627\u062a\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u062a\u0646\u0638\u06cc\u0645 \u06a9\u0648\u0646\u06a9\u0648 \u062a\u0647 \u0689\u06cc\u0631\u06cc \u0633\u062a\u0627\u06cc\u0646\u06d0!<\/p>\n

\u062a\u0627\u0633\u0648 \u067c\u0648\u0644 \u0631\u0627\u06a9 !!! \u062f \u062f\u06d0 \u0639\u0627\u0644\u064a \u0641\u0631\u0635\u062a \u0644\u067e\u0627\u0631\u0647 \u0645\u0646\u0646\u0647 \u060c \u062f \u0689\u06cc\u0631\u06cc \u06a9\u0644\u0648\u0646\u0648 \u062f\u0645\u062e\u0647 \u0641\u06a9\u0631 \u06a9\u0648\u0644 \u060c \u0627\u0648\u0633 \u062f\u0627 \u067e\u0647 \u0631\u0627\u062a\u0644\u0648\u0646\u06a9\u064a \u06a9\u06d0 \u062f \u0698\u0648\u0646\u062f \u06a9\u0648\u0644\u0648 \u067e\u0647 \u0685\u06cc\u0631 \u062f\u06cc! \u062e\u0648\u0634\u062d\u0627\u0644\u0647 \u06cc\u0645 \u0686\u06d0 \u062f \u0647\u063a\u06d0 \u0628\u0631\u062e\u0647 \u0648\u064a<\/p>\n

\u0632\u0647 \u062f \u0689\u0627\u06a9\u067c\u0631 \u06a9\u0648\u0644\u06cc\u0646 \u06ab\u06cc\u062a\u0627\u0631 \u0644\u0647 \u0644\u0627\u0633\u0647 \u0648\u0631\u06a9\u0648\u0645. \u0639\u0627\u0644\u064a \u062f\u0646\u062f\u0647!<\/p>\n

\u062f \u062f\u06d0 \u062a\u0646\u0638\u06cc\u0645 \u06a9\u0648\u0644\u0648 \u0644\u067e\u0627\u0631\u0647 \u0689\u06cc\u0631\u0647 \u0645\u0646\u0646\u0647 \u060c \u0648\u0627\u0642\u0639\u06cc\u0627 \u0632\u0645\u0627 \u062f \u0627\u0648\u0646\u06cd \u0685\u0631\u06ab\u0646\u062f\u0648\u0646\u0647!<\/p>\n

\u0644\u0647 \u0647\u0631\u0686\u0627 \u0685\u062e\u0647 \u0645\u0646\u0646\u0647 \u0627\u0648 \u067e\u0647 \u0631\u0627\u062a\u0644\u0648\u0646\u06a9\u064a \u06a9\u0627\u0644 \u06a9\u06d0 \u067e\u0647 \u06a9\u06cc\u0645\u0628\u0631\u062c \u06a9\u06d0 \u067e\u0647 \u0634\u062e\u0635\u06cc \u062a\u0648\u06ab\u0647 \u06ab\u0648\u0631\u0648 !!<\/p>\n

\u00a0<\/strong>\u0644\u0647 \u0645\u0648\u0696 \u0633\u0631\u0647 \u062f \u06cc\u0648\u0681\u0627\u06cc \u06a9\u06cc\u062f\u0648 \u0644\u067e\u0627\u0631\u0647 \u0633\u062a\u0627\u0633\u0648 \u067c\u0648\u0644\u0648 \u0685\u062e\u0647 \u0645\u0646\u0646\u0647!<\/strong><\/p>\n

[\/et_pb_toggle][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=\u201d1\u2033 module_class=\u201dfooter\u201d _builder_version=\u201d4.3.4\u2033 background_color=\u201d#29327a\u201d custom_margin=\u201d25px||||\u201d custom_padding=\u201d0|0px|0|0px|false|false\u201d z_index_tablet=\u201d500\u2033 border_width_top=\u201d12px\u201d border_color_top=\u201d#00b2e2\u2033 global_module=\u201d133\u2033 locked=\u201doff\u201d global_colors_info=\u201d{}\u201d][et_pb_row column_structure=\u201d1_4,1_4,1_2\u2033 make_equal=\u201don\u201d module_class=\u201det_pb_row_fullwidth\u201d _builder_version=\u201d4.16\u2033 width=\u201d89%\u201d width_tablet=\u201d80%\u201d width_phone=\u201d\u201d width_last_edited=\u201don|desktop\u201d max_width=\u201d89%\u201d max_width_tablet=\u201d80%\u201d max_width_phone=\u201d\u201d max_width_last_edited=\u201don|desktop\u201d z_index_tablet=\u201d500\u2033 make_fullwidth=\u201don\u201d width_unit=\u201doff\u201d custom_width_percent=\u201d100%\u201d global_colors_info=\u201d{}\u201d][et_pb_column type=\u201d1_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_cta button_url=\u201dhttps:\/\/www.progeriaresearch.org\/newsletter-signup\/\u201d button_text=\u201d\u0627\u0648\u0633 \u0644\u0627\u0633\u0644\u06cc\u06a9 \u0648\u06a9\u0693\u0626\u201d admin_label=\u201d\u062f \u062e\u0628\u0631 \u067e\u0627\u06bc\u06d0 \u0644\u067e\u0627\u0631\u0647 \u0644\u0627\u0633\u0644\u06cc\u06a9 \u0648\u06a9\u0693\u0626\u201d module_class=\u201dsign-btn\u201d _builder_version=\u201d4.16\u2033 header_font_size=\u201d25px\u201d background_color=\u201d#29327a\u201d animation_style=\u201dslide\u201d animation_direction=\u201dleft\u201d animation_intensity_slide=\u201d25%\u201d header_font_size_tablet=\u201d\u201d header_font_size_phone=\u201d30px\u201d header_font_size_last_edited=\u201don|desktop\u201d z_index_tablet=\u201d500\u2033 border_radii=\u201don|25px|25px|25px|25px\u201d global_colors_info=\u201d{}\u201d \u062a\u06bc\u06cd_bg_color__hover_enabled=\u201d\u0622\u0646\u201d \u062a\u06bc\u06cd_bg_color__hover=\u201d#8fd2ed\u201d \u062a\u06bc\u06cd_\u0633\u0631\u062d\u062f_\u0631\u0646\u06ab__hover_enabled=\u201d\u0622\u0646\u201d]<\/p>\n

\u06ab\u0689\u0648\u0646 \u06a9\u0648\u0644<\/h2>\n

\u0632\u0645\u0648\u0696 \u0644\u067e\u0627\u0631\u0647<\/h2>\n

\u062e\u0628\u0631\u067e\u0627\u06bc\u0647!<\/h2>\n

[\/et_pb_cta][\/et_pb_column][et_pb_column type=\u201d1_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info="{}" custom_padding__hover="|||"][et_pb_cta button_url="https:\/\/progeriaresearch.donorsupport.co\/-\/XZHJVWZR" button_text="\u0627\u0648\u0633 \u0645\u0631\u0633\u062a\u0647 \u0648\u06a9\u0693\u0626" admin_label="\u067e\u0647 \u06ab\u0689\u0647\u060c \u0645\u0648\u0696 \u0628\u0647 \u062f\u0631\u0645\u0644\u0646\u0647 \u0648\u0645\u0648\u0645\u0626! \u00bb module_class = "sign-btn" _builder_version="4.16" header_font_size="25px" background_color="#29327a" animation_style="slide" animation_direction="left" animation_intensity_slide="T_font_slide="T_font_size="251 \u067c\u0627\u0628\u0644\u06cc\u067c header_font_size_phone="30px" header_font_size_last_edited="on|desktop" body_font_size_tablet="" body_font_size_phone="" body_font_size_last_edited="on|desktop" z_index_tablet="500\u2033 border_radii=\u201don|25px|25px|25px|25px\u201d global_colors_info=\u201d{}\u201d button_bg_color__hover_enabled=\u201don\u201d button_bg_color__hover=\u201d#8fd2ed\u201d button_border_color__hover_enabled=\u201d]<\/p>\n

\u067e\u0647 \u06ab\u0689\u0647\u060c \u0645\u0648\u0696<\/h2>\n

\u0628\u0647<\/em><\/h2>\n

\u0639\u0644\u0627\u062c \u067e\u06cc\u062f\u0627 \u06a9\u0693\u0647!<\/h2>\n

[\/et_pb_cta][\/et_pb_column][et_pb_column type=\u201d1_2\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_image src=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2022\/11\/footerstrip2022-1200-\u00d7-300-px-1 .png" title_text="footerstrip2022 (1200 \u00d7 300 px) (1)" _builder_version="4.18.1\u2033 _module_preset="default" custom_margin="35px||||false|false" global_colors_info="{}"][\/et_pb_image][\/et_pb_coln \/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"

\u062f \u0681\u06cc\u0646\u0648 \u06a9\u0644\u06cc\u067e\u0648\u0646\u0648\u060c \u0639\u06a9\u0633\u0648\u0646\u0648\u060c \u062a\u0628\u0635\u0631\u0648\u060c \u0627\u0648 \u067e\u0648\u069a\u062a\u0646\u06d0 \u0627\u0648 \u0681\u0648\u0627\u0628\u0648\u0646\u0648 \u0685\u062e\u0647 \u062e\u0648\u0646\u062f \u0648\u0627\u062e\u0644\u0626!<\/p>","protected":false},"author":2,"featured_media":8394,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[3,2],"tags":[],"class_list":["post-8398","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-events","category-news"],"yoast_head":"\nPRF\u2019s 10th International Scientific Workshop - The Progeria Research Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/ps\/2020\/11\/02\/2020-workshop\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PRF\u2019s 10th International Scientific Workshop - The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"Enjoy some clips, photos, comments, and Q&A!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.progeriaresearch.org\/ps\/2020\/11\/02\/2020-workshop\/\" \/>\n<meta property=\"og:site_name\" content=\"The Progeria Research Foundation\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ProgeriaResearch\/\" \/>\n<meta property=\"article:published_time\" content=\"2020-11-02T23:57:17+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-12-09T11:43:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"275\" \/>\n\t<meta property=\"og:image:height\" content=\"275\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Karen Betournay\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@Progeria\" \/>\n<meta name=\"twitter:site\" content=\"@Progeria\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Karen Betournay\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"14 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/\"},\"author\":{\"name\":\"Karen Betournay\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/2be6cec85c11aaef7a7602636c5b9946\"},\"headline\":\"PRF\u2019s 10th International Scientific Workshop\",\"datePublished\":\"2020-11-02T23:57:17+00:00\",\"dateModified\":\"2022-12-09T11:43:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/\"},\"wordCount\":3602,\"publisher\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg\",\"articleSection\":[\"Events\",\"News\"],\"inLanguage\":\"ps\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/\",\"name\":\"PRF\u2019s 10th International Scientific Workshop - The Progeria Research Foundation\",\"isPartOf\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg\",\"datePublished\":\"2020-11-02T23:57:17+00:00\",\"dateModified\":\"2022-12-09T11:43:20+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#breadcrumb\"},\"inLanguage\":\"ps\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ps\",\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#primaryimage\",\"url\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg\",\"contentUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg\",\"width\":275,\"height\":275},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.progeriaresearch.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"PRF\u2019s 10th International Scientific Workshop\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#website\",\"url\":\"https:\/\/www.progeriaresearch.org\/ta\/\",\"name\":\"The Progeria Research Foundation\",\"description\":\"For the Children \u2665 For the Cure\",\"publisher\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.progeriaresearch.org\/ta\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ps\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\",\"name\":\"The Progeria Research Foundation\",\"url\":\"https:\/\/www.progeriaresearch.org\/ta\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ps\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png\",\"contentUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png\",\"width\":300,\"height\":86,\"caption\":\"The Progeria Research Foundation\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/ProgeriaResearch\/\",\"https:\/\/x.com\/Progeria\",\"https:\/\/www.instagram.com\/progeriaresearch\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/2be6cec85c11aaef7a7602636c5b9946\",\"name\":\"Karen Betournay\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ps\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/78c0520933a7d708c5e1a5788ec6799d5e2ad6a2a6d4ff2ca1e512861d12f533?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/78c0520933a7d708c5e1a5788ec6799d5e2ad6a2a6d4ff2ca1e512861d12f533?s=96&d=mm&r=g\",\"caption\":\"Karen Betournay\"},\"url\":\"https:\/\/www.progeriaresearch.org\/ps\/author\/karenb\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u062f PRF \u0644\u0633\u0645 \u0646\u0693\u06cc\u0648\u0627\u0644 \u0639\u0644\u0645\u064a \u0648\u0631\u06a9\u0634\u0627\u067e - \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0685\u06cc\u0693\u0646\u06cc\u0632 \u0628\u0646\u0633\u067c","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.progeriaresearch.org\/ps\/2020\/11\/02\/2020-workshop\/","og_locale":"en_US","og_type":"article","og_title":"PRF\u2019s 10th International Scientific Workshop - The Progeria Research Foundation","og_description":"Enjoy some clips, photos, comments, and Q&A!","og_url":"https:\/\/www.progeriaresearch.org\/ps\/2020\/11\/02\/2020-workshop\/","og_site_name":"The Progeria Research Foundation","article_publisher":"https:\/\/www.facebook.com\/ProgeriaResearch\/","article_published_time":"2020-11-02T23:57:17+00:00","article_modified_time":"2022-12-09T11:43:20+00:00","og_image":[{"width":275,"height":275,"url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg","type":"image\/jpeg"}],"author":"Karen Betournay","twitter_card":"summary_large_image","twitter_creator":"@Progeria","twitter_site":"@Progeria","twitter_misc":{"Written by":"Karen Betournay","Est. reading time":"14 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#article","isPartOf":{"@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/"},"author":{"name":"Karen Betournay","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/2be6cec85c11aaef7a7602636c5b9946"},"headline":"PRF\u2019s 10th International Scientific Workshop","datePublished":"2020-11-02T23:57:17+00:00","dateModified":"2022-12-09T11:43:20+00:00","mainEntityOfPage":{"@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/"},"wordCount":3602,"publisher":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#organization"},"image":{"@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#primaryimage"},"thumbnailUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg","articleSection":["Events","News"],"inLanguage":"ps"},{"@type":"WebPage","@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/","url":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/","name":"\u062f PRF \u0644\u0633\u0645 \u0646\u0693\u06cc\u0648\u0627\u0644 \u0639\u0644\u0645\u064a \u0648\u0631\u06a9\u0634\u0627\u067e - \u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0685\u06cc\u0693\u0646\u06cc\u0632 \u0628\u0646\u0633\u067c","isPartOf":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#primaryimage"},"image":{"@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#primaryimage"},"thumbnailUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg","datePublished":"2020-11-02T23:57:17+00:00","dateModified":"2022-12-09T11:43:20+00:00","breadcrumb":{"@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#breadcrumb"},"inLanguage":"ps","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/"]}]},{"@type":"ImageObject","inLanguage":"ps","@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#primaryimage","url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg","contentUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/09\/CircleWorkshop.jpg","width":275,"height":275},{"@type":"BreadcrumbList","@id":"https:\/\/www.progeriaresearch.org\/it\/2020\/11\/02\/2020-workshop\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.progeriaresearch.org\/"},{"@type":"ListItem","position":2,"name":"PRF\u2019s 10th International Scientific Workshop"}]},{"@type":"WebSite","@id":"https:\/\/www.progeriaresearch.org\/ta\/#website","url":"https:\/\/www.progeriaresearch.org\/ta\/","name":"\u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0685\u06cc\u0693\u0646\u06cc\u0632 \u0628\u0646\u0633\u067c","description":"\u062f \u0645\u0627\u0634\u0648\u0645\u0627\u0646\u0648 \u0644\u067e\u0627\u0631\u0647 \u2665 \u062f \u062f\u0631\u0645\u0644\u0646\u06d0 \u0644\u067e\u0627\u0631\u0647","publisher":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.progeriaresearch.org\/ta\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ps"},{"@type":"Organization","@id":"https:\/\/www.progeriaresearch.org\/ta\/#organization","name":"\u062f \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0685\u06cc\u0693\u0646\u06cc\u0632 \u0628\u0646\u0633\u067c","url":"https:\/\/www.progeriaresearch.org\/ta\/","logo":{"@type":"ImageObject","inLanguage":"ps","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/","url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png","contentUrl":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/05\/PRF_Logo_2019_optimized.png","width":300,"height":86,"caption":"The Progeria Research Foundation"},"image":{"@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ProgeriaResearch\/","https:\/\/x.com\/Progeria","https:\/\/www.instagram.com\/progeriaresearch\/"]},{"@type":"Person","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/2be6cec85c11aaef7a7602636c5b9946","name":"\u06a9\u0627\u0631\u0646 \u0628\u06cc\u067c\u0648\u0631\u0646\u064a","image":{"@type":"ImageObject","inLanguage":"ps","@id":"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/78c0520933a7d708c5e1a5788ec6799d5e2ad6a2a6d4ff2ca1e512861d12f533?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/78c0520933a7d708c5e1a5788ec6799d5e2ad6a2a6d4ff2ca1e512861d12f533?s=96&d=mm&r=g","caption":"Karen Betournay"},"url":"https:\/\/www.progeriaresearch.org\/ps\/author\/karenb\/"}]}},"_links":{"self":[{"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/posts\/8398","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/comments?post=8398"}],"version-history":[{"count":0,"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/posts\/8398\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/media\/8394"}],"wp:attachment":[{"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/media?parent=8398"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/categories?post=8398"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.progeriaresearch.org\/ps\/wp-json\/wp\/v2\/tags?post=8398"}],"curies":[{"name":"\u0689\u0628\u0644\u06cc\u0648 \u067e\u064a","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}