{"id":347,"date":"2019-04-15T13:32:41","date_gmt":"2019-04-15T13:32:41","guid":{"rendered":"http:\/\/beta.progeriaresearch.org.php72-4.lan3-1.websitetestlink.com\/?page_id=347"},"modified":"2024-12-03T12:37:25","modified_gmt":"2024-12-03T17:37:25","slug":"about-us","status":"publish","type":"page","link":"https:\/\/www.progeriaresearch.org\/pt\/about-us\/","title":{"rendered":"Sobre"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.16&#8243; border_width_bottom=&#8221;55px&#8221; border_color_bottom=&#8221;#29327a&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_header _builder_version=&#8221;4.16&#8243; title_font_size=&#8221;55&#8243; background_color=&#8221;#29327a&#8221; background_image=&#8221;https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/About-Header.jpg&#8221; background_position=&#8221;center_left&#8221; custom_padding=&#8221;9vw||9vw||true&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;|56px||&#8221; custom_padding_last_edited=&#8221;on|desktop&#8221; title_font_size_tablet=&#8221;45px&#8221; title_font_size_phone=&#8221;40px&#8221; title_font_size_last_edited=&#8221;on|phone&#8221; z_index_tablet=&#8221;500&#8243; custom_css_main_element=&#8221;background-position: center 18% !important;&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>About<\/h1>\n<p>[\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;1&#8243; specialty=&#8221;on&#8221; padding_left_1=&#8221;35px&#8221; padding_left_2=&#8221;35px&#8221; padding_2_tablet=&#8221;|||0px&#8221; padding_2_phone=&#8221;|||0px&#8221; padding_2_last_edited=&#8221;on|desktop&#8221; module_class_1=&#8221;sidebar-secondary-nav&#8221; module_class=&#8221;handprint-bg&#8221; _builder_version=&#8221;4.16&#8243; background_image=&#8221;https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/blue-handprint-only.png&#8221; parallax=&#8221;on&#8221; parallax_method=&#8221;off&#8221; inner_width=&#8221;100%&#8221; inner_max_width=&#8221;100%&#8221; custom_padding=&#8221;0|0px|54px|0px|false|false&#8221; z_index_tablet=&#8221;500&#8243; border_width_top=&#8221;10px&#8221; border_color_top=&#8221;#8fd2ed&#8221; use_custom_width=&#8221;on&#8221; width_unit=&#8221;off&#8221; custom_width_percent=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_sidebar area=&#8221;et_pb_widget_area_16&#8243; disabled_on=&#8221;on|on|off&#8221; module_class=&#8221;subpage-sidebars&#8221; _builder_version=&#8221;4.16&#8243; animation_style=&#8221;fade&#8221; z_index_tablet=&#8221;500&#8243; border_width_right=&#8221;5px&#8221; global_colors_info=&#8221;{}&#8221;]<br \/>\n[\/et_pb_sidebar][\/et_pb_column][et_pb_column type=&#8221;3_4&#8243; specialty_columns=&#8221;3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;|0px|||false|false&#8221; custom_padding=&#8221;|15px|0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;3_4&#8243; _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Mission&#8221; _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#00B2E2&#8243; custom_margin=&#8221;20px||20px||false|false&#8221; custom_padding=&#8221;20px||20px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1 style=\"text-align: center;\">Mission<\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;mission text&#8221; _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\">To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.<\/p>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Vision&#8221; _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#00B2E2&#8243; custom_margin=&#8221;20px||20px||false|false&#8221; custom_padding=&#8221;20px||20px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1 style=\"text-align: center;\">Vision<\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;vision text&#8221; _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\">A world in which every child with Progeria is cured.<\/p>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Values&#8221; _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#00B2E2&#8243; custom_margin=&#8221;20px||20px||false|false&#8221; custom_padding=&#8221;20px||20px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1 style=\"text-align: center;\">Values<\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Values text&#8221; _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p class=\"xmsonormal\">PRF is a vibrant organization with a deep commitment to finding treatments and the cure for Progeria. We operate in a fast-paced, dynamic environment that values innovation, collaboration, and integrity.\u00a0 <b>Our values<\/b> define who we are, guide expected behaviors at all levels of the organization, and provide the framework for how we interact with those with progeria and their families, progeria researchers and clinicians, research-related program partners, donors, volunteers, and other supporters of our mission:<\/p>\n<ul type=\"disc\">\n<li class=\"xmsolistparagraph\">PRF staff and Board are <b>committed<\/b> to and <b>passionate<\/b> about the work we do each day.<\/li>\n<li class=\"xmsolistparagraph\">Our programs are <b>innovative<\/b> and <b>research-driven<\/b>. We are <b>leaders<\/b> in our field.<\/li>\n<li class=\"xmsolistparagraph\">Business operations are <b>transparent<\/b> while <b>respectful<\/b> of the privacy of our donors and the families we serve.<\/li>\n<li class=\"xmsolistparagraph\">We <b>sustain<\/b> and <b>reinvest<\/b> in our mission by wisely managing our human and material resources, recognizing the <b>responsibility<\/b> and <b>accountability<\/b> we have for <b>stewardship<\/b> of the resources entrusted to us.<\/li>\n<li class=\"xmsolistparagraph\">We strive to provide <b>information<\/b> that is accurate, objective, relevant, timely and understandable.<\/li>\n<li class=\"xmsolistparagraph\"><b>Teamwork<\/b> is an integral part of everything we do, as we truly believe that <b>Together, we <i>WILL<\/i> find the cure! <\/b><\/li>\n<\/ul>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Our Story&#8221; _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#00B2E2&#8243; custom_margin=&#8221;20px||20px||false|false&#8221; custom_padding=&#8221;20px||20px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1 style=\"text-align: center;\">Our Story<\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Our Story text&#8221; _builder_version=&#8221;4.19.5&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; z_index_tablet=&#8221;500&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" alignleft\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/6.-airway-mgt-anesthesia-square.jpg\" width=\"319\" height=\"319\" \/>Progeria is a rare, fatal, \u201crapid aging\u201d disease. Without lonafarnib treatment, all children with Progeria die of heart disease at an average age of 14.5 years. The Progeria Research Foundation (PRF) was founded in 1999 in response to the complete lack of progress being made to help children with Progeria.<\/p>\n<p>Today, PRF continues to be the only organization in the world solely dedicated to finding treatments and the cure for Progeria. We have filled a void, taking these children out of the background where they had been for over 100 years and putting them and Progeria at the forefront of scientific efforts.<\/p>\n<p>In just a relatively short time, we have achieved extraordinary progress towards our mission: the Progeria gene discovery in 2003, first-ever clinical drug trials initiated in 2007 to explore a drug called lonafarnib, and approval by the U.S. Food and Drug Administration (FDA) in 2020 for lonafarnib, the first-ever treatment for Progeria, which is now the standard-of-care. This historic milestone put Progeria among the 5% of rare diseases that have an FDA approved treatment! In addition, we&#8217;ve achieved extensive global awareness of the disease and PRF\u2019s work, and confirmation of critical biological links between Progeria, heart disease and the aging we all experience. In 2023, PRF researchers developed a biomarker for Progeria, enabling researchers to more quickly and accurately gauge the effectiveness of new treatment candidates much earlier in a clinical trial, <strong>accelerating the pace of progress toward better treatments and the cure<\/strong>.<\/p>\n<p>From an obscure, ignored disease at our founding in 1999, to treatment and global recognition today \u2013 we celebrate an unprecedented timeline of progress in the world of medical research! Our accomplishments are being praised as a \u201cscientific sprint\u201d as we forge ahead in this race against time.<\/p>\n<p>All of this progress is due in large part to the establishment of PRF\u2019s research-related programs and services. Developed with insightful determination, they provide the resources needed not only to advance the field of Progeria, but also to discover what Progeria can tell us about heart disease and aging.<\/p>\n<p>With the support of dedicated staff and volunteers, a talented board of directors, courageous families, and thousands of generous people around the world, we are pushing Progeria research forward towards discovery, treatments, and cure. And along the way, we are learning a tremendous amount about ourselves.<\/p>\n<p>Please enjoy the pages of this website, which detail PRF\u2019s programs, progress and partners. The historic Progeria treatment discovery, tremendous success of our global campaign to identify all children with Progeria, and clinical drug trials and drug discovery are contributing to exciting and productive times as we edge ever-closer to our ultimate goal of a cure.\u00a0 Your love and support for children with Progeria makes these exciting strides possible.<\/p>\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner custom_padding_last_edited=&#8221;on|phone&#8221; disabled_on=&#8221;on|on|&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;0px|35px|35px||false|false&#8221; custom_padding_tablet=&#8221;|35px||35px||true&#8221; custom_padding_phone=&#8221;&#8221; animation_direction=&#8221;top&#8221; z_index_tablet=&#8221;500&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;3_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_cta button_url=&#8221;https:\/\/progeriaresearch.donorsupport.co\/-\/XZHJVWZR&#8221; button_text=&#8221;Donate Now&#8221; _builder_version=&#8221;4.27.2&#8243; background_color=&#8221;rgba(0,178,226,0)&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#ffffff&#8221; button_font=&#8221;||||||||&#8221; background_layout=&#8221;light&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<div id=\"pastingspan1\">\n<h4>Together, we <em>WILL<\/em> find the cure!<\/h4>\n<article>Your donation helps The Progeria Research Foundation\u00a0<em><strong>treat<\/strong><\/em>\u00a0children with Progeria today and\u00a0<em><strong>cure<\/strong><\/em><strong>\u00a0<\/strong>them in the future.<\/article>\n<\/div>\n<p>[\/et_pb_cta][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner column_structure=&#8221;1_2,1_2&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; disabled_on=&#8221;off|off|on&#8221; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;39.4375px|35px|35px||false|false&#8221; custom_padding_tablet=&#8221;|35px||35px||true&#8221; custom_padding_phone=&#8221;&#8221; animation_direction=&#8221;top&#8221; z_index_tablet=&#8221;500&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner type=&#8221;1_2&#8243; saved_specialty_column_type=&#8221;3_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2019\/04\/6.-airway-mgt-anesthesia-square.jpg&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; admin_label=&#8221;Image (mobile only)&#8221; _builder_version=&#8221;4.16&#8243; z_index_tablet=&#8221;500&#8243; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column_inner][et_pb_column_inner type=&#8221;1_2&#8243; saved_specialty_column_type=&#8221;3_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Text (mobile only)&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; z_index_tablet=&#8221;500&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Progeria is a rare, fatal, \u201crapid aging\u201d disease. Without the discovery of new treatments, all children with Progeria will die of heart disease at an average age of 14 years. The Progeria Research Foundation (PRF) was founded in 1999 in response to the complete lack of progress being made to help children with Progeria. Our original mission: to discover the cause, treatments and cure for Progeria.* Today, PRF continues to be the only organization in the world solely dedicated to this mission. We have filled a void, taking these children out of the background where they had been for over 100 years and putting them and Progeria at the forefront of scientific efforts.<\/p>\n<p>In just a relatively short time, we have achieved extraordinary progress towards our mission: the Progeria gene discovery in 2003, first-ever clinical drug trials initiated in 2007, and the 2012 results of that first trial being the discovery of the first treatment for Progeria. In addition, we have achieved extensive global awareness of the disease and PRF\u2019s work, and confirmation of critical biological links between Progeria, heart disease and the aging we all experience. From an obscure, ignored disease to treatment and global recognition \u2013 an unheard of timeline in the world of medical research! Our accomplishments are being praised as a \u201cscientific sprint\u201d** as we forge ahead in this race against time.<\/p>\n<p>All of this progress is due in large part to the creation of PRF\u2019s research-related programs and services. Developed with insightful determination, they provide the resources needed not only to advance the field of Progeria, but also to discover what Progeria can tell us about heart disease and aging.<\/p>\n<p>With the support of dedicated staff and volunteers, a talented board of directors, courageous families, and thousands of generous people around the world, we are pushing the field of Progeria forward towards discovery, treatments, and cure. And along the way, we are learning a tremendous amount about ourselves.<\/p>\n<p>Please enjoy the pages of this web site, which detail PRF\u2019s programs, progress and partners. The historic Progeria treatment discovery, tremendous success of our global campaign to identify all children with Progeria, and clinical drug trials and drug discovery are contributing to exciting and productive times as we edge ever-closer to our ultimate goal of a cure.Your love and support for children with Progeria makes these exciting strides possible.<\/p>\n<p>[\/et_pb_text][et_pb_cta button_url=&#8221;#&#8221; button_text=&#8221;Donate Now&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(0,178,226,0)&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#ffffff&#8221; button_font=&#8221;||||||||&#8221; background_layout=&#8221;light&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div id=\"pastingspan1\">\n<h4>Together, we <em>WILL<\/em> find the cure!<\/h4>\n<article>Your donation helps The Progeria Research Foundation\u00a0<em><strong>treat<\/strong><\/em>\u00a0children with Progeria today and\u00a0<em><strong>cure<\/strong><\/em><strong>\u00a0<\/strong>them in the future.<\/article>\n<\/div>\n<p>[\/et_pb_cta][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; module_class=&#8221;footer&#8221; _builder_version=&#8221;4.21.0&#8243; background_color=&#8221;#29327a&#8221; custom_margin=&#8221;-2px|||||&#8221; custom_padding=&#8221;0|0px|0|0px|false|false&#8221; z_index_tablet=&#8221;500&#8243; border_width_top=&#8221;12px&#8221; border_color_top=&#8221;#00b2e2&#8243; global_module=&#8221;133&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row_inner column_structure=&#8221;1_3,1_3,1_3&#8243; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Row&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;277px&#8221; custom_margin=&#8221;|20px|30px||false|false&#8221; custom_padding=&#8221;0px|30px|0px||false|false&#8221; 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