{"id":13809,"date":"2021-09-23T16:24:47","date_gmt":"2021-09-23T20:24:47","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=13809"},"modified":"2023-10-02T10:28:23","modified_gmt":"2023-10-02T14:28:23","slug":"2021-newsletter","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/pt\/2021\/09\/23\/2021-newsletter\/","title":{"rendered":"Receba aqui o Boletim Anual da PRF de 2021!"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2021\/09\/Newsletter-2021-clip-235&#215;300.png&#8221; title_text=&#8221;Newsletter 2021 clip&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"font-weight: 400;\">Confira nossa newsletter para ler sobre a aprova\u00e7\u00e3o do FDA para o primeiro tratamento para Progeria, saiba como a pesquisa que financiamos fez um progresso not\u00e1vel em dire\u00e7\u00e3o \u00e0 cura por meio de terapias gen\u00e9ticas e de RNA e fique por dentro de todos os marcos emocionantes que estamos comemorando agora. Aqui est\u00e1 uma pr\u00e9via de nossas duas principais hist\u00f3rias:<\/p>\n<p style=\"font-weight: 400;\"><strong>Primeiro tratamento para Progeria recebe aprova\u00e7\u00e3o da FDA<br \/><\/strong>Em 20 de novembro de 2020, em parceria com a Eiger Biopharmaceuticals, a PRF atingiu uma parte importante da nossa miss\u00e3o: lonafarnib, o primeiro tratamento para Progeria, recebeu aprova\u00e7\u00e3o da US Food &amp; Drug Administration (FDA). A Progeria agora se junta a menos de 5% das 7.000 doen\u00e7as raras conhecidas com um tratamento aprovado pela FDA.<\/p>\n<p style=\"font-weight: 400;\"><strong>Avan\u00e7os nos campos de vanguarda das terapias gen\u00e9ticas e de RNA<br \/><\/strong>Houve um tremendo progresso recentemente em dois tipos de terapia que podem um dia se traduzir na cura para a Progeria. Um estudo de edi\u00e7\u00e3o gen\u00e9tica em um modelo de camundongo de Progeria corrigiu a muta\u00e7\u00e3o que causa a Progeria em muitas c\u00e9lulas, melhorou os principais sintomas da doen\u00e7a e aumentou drasticamente a expectativa de vida nos camundongos. Dois outros estudos sobre o uso de terap\u00eauticas de RNA mostraram redu\u00e7\u00e3o significativa do RNA t\u00f3xico produtor de progerina e aumento substancial na sobreviv\u00eancia dos camundongos.<\/p>\n<p style=\"font-weight: 400;\">[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2021\/09\/PRF-2021-Newsletter_FINAL.pdf&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;View the Full  2021 Newsletter&#8221; _builder_version=&#8221;4.16&#8243; background_layout=&#8221;dark&#8221; custom_margin=&#8221;5px||||false|false&#8221; z_index_tablet=&#8221;500&#8243; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>Confira nosso boletim informativo para ler sobre a aprova\u00e7\u00e3o do FDA para o primeiro tratamento para Prog\u00e9ria, saiba como a pesquisa que financiamos fez um progresso not\u00e1vel em dire\u00e7\u00e3o \u00e0 cura por meio de terapias gen\u00e9ticas e de RNA e fique por dentro de todos os marcos emocionantes que estamos comemorando agora.<\/p>","protected":false},"author":2,"featured_media":13817,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,1],"tags":[],"class_list":["post-13809","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Newsletter 2021 | The Progeria Research Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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