{"id":2091,"date":"2008-05-16T13:50:49","date_gmt":"2008-05-16T13:50:49","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=2091"},"modified":"2020-12-10T12:55:01","modified_gmt":"2020-12-10T17:55:01","slug":"first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/ta\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/","title":{"rendered":"\u0bae\u0bc1\u0ba4\u0ba9\u0bcd\u0bae\u0bc1\u0bb1\u0bc8\u0baf\u0bbe\u0b95 \u0baa\u0bcd\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe \u0bae\u0bb0\u0bc1\u0ba4\u0bcd\u0ba4\u0bc1\u0bb5 \u0bae\u0bb0\u0bc1\u0ba8\u0bcd\u0ba4\u0bc1 \u0b9a\u0bcb\u0ba4\u0ba9\u0bc8 \u0b85\u0bb0\u0bc8-\u0bb5\u0bb4\u0bbf\u0b95\u0bcd \u0b95\u0bc1\u0bb1\u0bbf\u0baf\u0bc8\u0ba4\u0bcd \u0ba4\u0bbe\u0ba3\u0bcd\u0b9f\u0bbf\u0baf\u0ba4\u0bc1!"},"content":{"rendered":"<p>[et_pb_section fb_built=\u201d1\u2033 _builder_version=\u201d3.22\u2033][et_pb_row 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title_text=&#8221;Julieta-Aug07&#8243; admin_label=&#8221;Julieta&#8221; _builder_version=&#8221;4.6.5&#8243; _module_preset=&#8221;default&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.6.5&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.6.5&#8243; _module_preset=&#8221;default&#8221;]<\/p>\n<p><em><strong>\u0b85\u0bb0\u0bcd\u0b9c\u0bc6\u0ba9\u0bcd\u0b9f\u0bbf\u0ba9\u0bbe\u0bb5\u0bc8\u0b9a\u0bcd \u0b9a\u0bc7\u0bb0\u0bcd\u0ba8\u0bcd\u0ba4 \u0b9c\u0bc2\u0bb2\u0bbf\u0baf\u0bbe\u0b9f\u0bcd\u0b9f\u0bbe<\/strong><\/em><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.6.5&#8243; _module_preset=&#8221;default&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.6.5&#8243; _module_preset=&#8221;default&#8221;][et_pb_testimonial author=&#8221;Francis Collins, MD, PhD, Director of the National Human Genome Research Institute that mapped the human 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\u0b9a\u0bbf\u0b95\u0bbf\u0b9a\u0bcd\u0b9a\u0bc8\u0baf\u0bc8 \u0b86\u0bb0\u0bbe\u0baf\u0bcd\u0b9a\u0bcd\u0b9a\u0bbf\u0baf\u0bbe\u0bb3\u0bb0\u0bcd\u0b95\u0bb3\u0bcd \u0b95\u0ba3\u0bcd\u0b9f\u0bb1\u0bbf\u0ba8\u0bcd\u0ba4\u0bc1\u0bb3\u0bcd\u0bb3\u0ba9\u0bb0\u0bcd, \u0bae\u0bc7\u0bb2\u0bc1\u0bae\u0bcd \u0bae\u0bb0\u0bc1\u0ba8\u0bcd\u0ba4\u0bc1\u0b9f\u0ba9\u0bcd \u0bae\u0ba9\u0bbf\u0ba4 \u0b9a\u0bcb\u0ba4\u0ba9\u0bc8\u0b95\u0bcd\u0b95\u0bc1 \u0b86\u0ba4\u0bb0\u0bb5\u0bb3\u0bbf\u0b95\u0bcd\u0b95\u0bc1\u0bae\u0bcd \u0b86\u0baf\u0bcd\u0bb5\u0bc1\u0b95\u0bb3\u0bc8 \u0b86\u0baf\u0bcd\u0bb5\u0b95\u0ba4\u0bcd\u0ba4\u0bbf\u0bb2\u0bcd \u0bae\u0bc7\u0bb1\u0bcd\u0b95\u0bca\u0ba3\u0bcd\u0b9f\u0bc1\u0bb3\u0bcd\u0bb3\u0ba9\u0bb0\u0bcd.\u00a0<a href=\"https:\/\/www.progeriaresearch.org\/ta\/2006\/02\/16\/three-studies-released-that-bring-us-closer-than-ever-to-understanding-progeria-and-to-disease-treatment\/\">\u0b87\u0b99\u0bcd\u0b95\u0bc7 \u0b95\u0bbf\u0bb3\u0bbf\u0b95\u0bcd \u0b9a\u0bc6\u0baf\u0bcd\u0baf\u0bb5\u0bc1\u0bae\u0bcd<\/a>\u00a0\u0b86\u0bb0\u0bbe\u0baf\u0bcd\u0b9a\u0bcd\u0b9a\u0bbf \u0baa\u0bb1\u0bcd\u0bb1\u0bbf\u0baf \u0b95\u0bc2\u0b9f\u0bc1\u0ba4\u0bb2\u0bcd \u0bb5\u0bbf\u0bb5\u0bb0\u0b99\u0bcd\u0b95\u0bb3\u0bc1\u0b95\u0bcd\u0b95\u0bc1.<\/div>\n<div>\u00a0<\/div>\n<div>\n<div><strong>\u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe\u0bb5\u0bbf\u0bb2\u0bcd \u0b87\u0ba8\u0bcd\u0ba4 \u0bae\u0bb0\u0bc1\u0ba8\u0bcd\u0ba4\u0bc1 \u0b8e\u0baa\u0bcd\u0baa\u0b9f\u0bbf \u0bb5\u0bc7\u0bb2\u0bc8 \u0b9a\u0bc6\u0baf\u0bcd\u0baf\u0bc1\u0bae\u0bcd?<\/strong><\/div>\n<div>\u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe\u0bb5\u0bc1\u0b95\u0bcd\u0b95\u0bc1 \u0b95\u0bbe\u0bb0\u0ba3\u0bae\u0bcd \u0b8e\u0ba9\u0bcd\u0bb1\u0bc1 \u0ba8\u0bbe\u0bae\u0bcd \u0ba8\u0bae\u0bcd\u0baa\u0bc1\u0bae\u0bcd \u0baa\u0bc1\u0bb0\u0ba4\u0bae\u0bcd \u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc6\u0bb0\u0bbf\u0ba9\u0bcd \u0b8e\u0ba9\u0bcd\u0bb1\u0bc1 \u0b85\u0bb4\u0bc8\u0b95\u0bcd\u0b95\u0baa\u0bcd\u0baa\u0b9f\u0bc1\u0b95\u0bbf\u0bb1\u0ba4\u0bc1. \u0b9a\u0bbe\u0ba4\u0bbe\u0bb0\u0ba3 \u0b9a\u0bc6\u0bb2\u0bcd \u0b9a\u0bc6\u0baf\u0bb2\u0bcd\u0baa\u0bbe\u0b9f\u0bcd\u0b9f\u0bc8\u0ba4\u0bcd \u0ba4\u0b9f\u0bc1\u0b95\u0bcd\u0b95\u0bb5\u0bc1\u0bae\u0bcd, \u0baa\u0bcd\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe\u0bb5\u0bc8 \u0b8f\u0bb1\u0bcd\u0baa\u0b9f\u0bc1\u0ba4\u0bcd\u0ba4\u0bb5\u0bc1\u0bae\u0bcd, \u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc6\u0bb0\u0bbf\u0ba9\u0bcd \u0baa\u0bc1\u0bb0\u0ba4\u0ba4\u0bcd\u0ba4\u0bc1\u0b9f\u0ba9\u0bcd &quot;\u0b83\u0baa\u0bbe\u0bb0\u0bcd\u0ba9\u0bc6\u0b9a\u0bbf\u0bb2\u0bcd \u0b95\u0bc1\u0bb4\u0bc1&quot; \u0b8e\u0ba9\u0bcd\u0bb1\u0bc1 \u0b85\u0bb4\u0bc8\u0b95\u0bcd\u0b95\u0baa\u0bcd\u0baa\u0b9f\u0bc1\u0bae\u0bcd \u0b92\u0bb0\u0bc1 \u0bae\u0bc2\u0bb2\u0b95\u0bcd\u0b95\u0bc2\u0bb1\u0bc1 \u0b87\u0ba3\u0bc8\u0b95\u0bcd\u0b95\u0baa\u0bcd\u0baa\u0b9f \u0bb5\u0bc7\u0ba3\u0bcd\u0b9f\u0bc1\u0bae\u0bcd. \u0baa\u0bcd\u0bb0\u0bcb\u0b9c\u0bc6\u0bb0\u0bbf\u0ba9\u0bcd \u0bae\u0bc0\u0ba4\u0bc1 \u0b83\u0baa\u0bbe\u0bb0\u0bcd\u0ba9\u0bc6\u0b9a\u0bbf\u0bb2\u0bcd \u0b95\u0bc1\u0bb4\u0bc1\u0bb5\u0bbf\u0ba9\u0bcd \u0b87\u0ba3\u0bc8\u0baa\u0bcd\u0baa\u0bc8\u0ba4\u0bcd \u0ba4\u0b9f\u0bc1\u0baa\u0bcd\u0baa\u0ba4\u0ba9\u0bcd \u0bae\u0bc2\u0bb2\u0bae\u0bcd (\u0ba4\u0b9f\u0bc1\u0baa\u0bcd\u0baa\u0ba4\u0ba9\u0bcd \u0bae\u0bc2\u0bb2\u0bae\u0bcd) FTI\u0b95\u0bb3\u0bcd \u0b9a\u0bc6\u0baf\u0bb2\u0bcd\u0baa\u0b9f\u0bc1\u0b95\u0bbf\u0ba9\u0bcd\u0bb1\u0ba9. \u0b8e\u0ba9\u0bb5\u0bc7 \u0baa\u0bcd\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe \u0b89\u0bb3\u0bcd\u0bb3 \u0b95\u0bc1\u0bb4\u0ba8\u0bcd\u0ba4\u0bc8\u0b95\u0bb3\u0bbf\u0bb2\u0bcd FTI \u0bae\u0bb0\u0bc1\u0ba8\u0bcd\u0ba4\u0bc1 \u0b87\u0ba8\u0bcd\u0ba4 \u0b83\u0baa\u0bbe\u0bb0\u0bcd\u0ba9\u0bc6\u0b9a\u0bbf\u0bb2\u0bcd \u0b95\u0bc1\u0bb4\u0bc1 \u0b87\u0ba3\u0bc8\u0baa\u0bcd\u0baa\u0bc8\u0ba4\u0bcd \u0ba4\u0b9f\u0bc1\u0b95\u0bcd\u0b95\u0bc1\u0bae\u0bbe\u0ba9\u0bbe\u0bb2\u0bcd, \u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc6\u0bb0\u0bbf\u0ba9\u0bcd &quot;\u0bae\u0bc1\u0b9f\u0b99\u0bcd\u0b95\u0bbf&quot; \u0bae\u0bb1\u0bcd\u0bb1\u0bc1\u0bae\u0bcd \u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe \u0bae\u0bc7\u0bae\u0bcd\u0baa\u0b9f\u0bc1\u0ba4\u0bcd\u0ba4\u0baa\u0bcd\u0baa\u0b9f\u0bb2\u0bbe\u0bae\u0bcd.<\/div>\n<\/div>\n<div style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2096 size-full aligncenter\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/FTI-3-cell-image-crpd.jpg\" alt=\"\" width=\"375\" height=\"89\" srcset=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/FTI-3-cell-image-crpd.jpg 375w, https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/FTI-3-cell-image-crpd-300x71.jpg 300w\" sizes=\"(max-width: 375px) 100vw, 375px\" \/> <em><strong>\u0b8e\u0b83\u0baa\u0bcd.\u0b9f\u0bbf.\u0b90 \u0baa\u0baf\u0ba9\u0bcd\u0baa\u0b9f\u0bc1\u0ba4\u0bcd\u0ba4\u0baa\u0bcd\u0baa\u0b9f\u0bc1\u0bae\u0bcd\u0baa\u0bcb\u0ba4\u0bc1 \u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe \u0b9a\u0bc6\u0bb2\u0bcd\u0b95\u0bb3\u0bcd \u0b87\u0baf\u0bb2\u0bcd\u0baa\u0bbe\u0b95\u0bcd\u0b95\u0baa\u0bcd\u0baa\u0b9f\u0bc1\u0b95\u0bbf\u0ba9\u0bcd\u0bb1\u0ba9. \u0b95\u0bc7\u0baa\u0bc6\u0bb2\u0bcd \u0bae\u0bb1\u0bcd\u0bb1\u0bc1\u0bae\u0bcd \u0baa\u0bb2\u0bb0\u0bcd., PNAS, 2005. \u0b87\u0baf\u0bb2\u0bcd\u0baa\u0bbe\u0ba9 \u0b9a\u0bc6\u0bb2\u0bcd. \u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe \u0b9a\u0bc6\u0bb2\u0bcd. \u0b8e\u0b83\u0baa\u0bcd\u0b9f\u0bbf\u0b90 \u0b9a\u0bbf\u0b95\u0bbf\u0b9a\u0bcd\u0b9a\u0bc8\u0b95\u0bcd\u0b95\u0bc1\u0baa\u0bcd \u0baa\u0bbf\u0bb1\u0b95\u0bc1 \u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe \u0b9a\u0bc6\u0bb2\u0bcd<\/strong><\/em><\/div>\n<div>\u00a0<\/div>\n<div>\n<div><strong>\u0b9a\u0bcb\u0ba4\u0ba9\u0bc8\u0b95\u0bcd\u0b95\u0bc1 PRF \u0b8e\u0bb5\u0bcd\u0bb5\u0bb3\u0bb5\u0bc1 \u0b9a\u0bc6\u0bb2\u0bb5\u0bbe\u0b95\u0bc1\u0bae\u0bcd? <\/strong>\u00a0\u0b9a\u0bcb\u0ba4\u0ba9\u0bc8\u0b95\u0bcd\u0b95\u0bc1 PRF $2 \u0bae\u0bbf\u0bb2\u0bcd\u0bb2\u0bbf\u0baf\u0ba9\u0bcd \u0b9f\u0bbe\u0bb2\u0bb0\u0bcd\u0b95\u0bb3\u0bcd \u0b9a\u0bc6\u0bb2\u0bb5\u0bbe\u0b95\u0bc1\u0bae\u0bcd \u0b8e\u0ba9\u0bcd\u0bb1\u0bc1 \u0bae\u0ba4\u0bbf\u0baa\u0bcd\u0baa\u0bbf\u0b9f\u0bc1\u0b95\u0bbf\u0bb1\u0bcb\u0bae\u0bcd. \u0b87\u0ba4\u0bc1 \u0bae\u0bb0\u0bc1\u0ba4\u0bcd\u0ba4\u0bc1\u0bb5 \u0baa\u0bb0\u0bbf\u0b9a\u0bcb\u0ba4\u0ba9\u0bc8, \u0bae\u0bca\u0bb4\u0bbf\u0baa\u0bc6\u0baf\u0bb0\u0bcd\u0baa\u0bcd\u0baa\u0bbe\u0bb3\u0bb0\u0bcd\u0b95\u0bb3\u0bcd, \u0bb5\u0bbf\u0bae\u0bbe\u0ba9\u0b99\u0bcd\u0b95\u0bb3\u0bcd, \u0b89\u0ba3\u0bb5\u0bc1, \u0b89\u0bb1\u0bc8\u0bb5\u0bbf\u0b9f\u0bae\u0bcd \u0bae\u0bb1\u0bcd\u0bb1\u0bc1\u0bae\u0bcd \u0b9a\u0bbf\u0bb2 \u0bae\u0bb0\u0bc1\u0ba4\u0bcd\u0ba4\u0bc1\u0bb5 \u0b9a\u0bc6\u0bb2\u0bb5\u0bc1\u0b95\u0bb3\u0bc1\u0b95\u0bcd\u0b95\u0bc1 \u0b9a\u0bc6\u0bb2\u0bc1\u0ba4\u0bcd\u0ba4\u0bc1\u0bae\u0bcd. <img loading=\"lazy\" decoding=\"async\" class=\"alignright\" src=\"https:\/\/web.archive.org\/web\/20170218013638im_\/https:\/\/www.progeriaresearch.org\/assets\/images\/donate_images\/Capsule-1_9.jpg\" alt=\"\" width=\"150\" height=\"299\" align=\"right\" hspace=\"3\" vspace=\"3\" \/>\u0b85\u0ba8\u0bcd\u0ba4 2\u00bd \u0bb5\u0bb0\u0bc1\u0b9f \u0b95\u0bbe\u0bb2\u0ba4\u0bcd\u0ba4\u0bbf\u0bb2\u0bcd.<\/div>\n<div><strong>\u00a0<\/strong><\/div>\n<div><strong><em>\u0b89\u0b99\u0bcd\u0b95\u0bb3\u0bcd \u0ba8\u0ba9\u0bcd\u0b95\u0bca\u0b9f\u0bc8 \u0b87\u0ba8\u0bcd\u0ba4 \u0b9a\u0bcb\u0ba4\u0ba9\u0bc8\u0baf\u0bc8 \u0ba8\u0b9f\u0ba4\u0bcd\u0ba4 \u0b89\u0ba4\u0bb5\u0bc1\u0bae\u0bcd.<\/em><\/strong><\/div>\n<div>\n<p><em>\u0b87\u0ba8\u0bcd\u0ba4 \u0b9a\u0bcb\u0ba4\u0ba9\u0bc8\u0b95\u0bcd\u0b95\u0bc1 \u0ba8\u0bbf\u0ba4\u0bbf\u0baf\u0bb3\u0bbf\u0b95\u0bcd\u0b95 PRF \u0ba4\u0bcb\u0bb0\u0bbe\u0baf\u0bae\u0bbe\u0b95 $2 \u0bae\u0bbf\u0bb2\u0bcd\u0bb2\u0bbf\u0baf\u0ba9\u0bcd \u0b9f\u0bbe\u0bb2\u0bb0\u0bcd\u0b95\u0bb3\u0bc8 \u0ba4\u0bbf\u0bb0\u0b9f\u0bcd\u0b9f \u0bb5\u0bc7\u0ba3\u0bcd\u0b9f\u0bc1\u0bae\u0bcd, \u0b9c\u0bc2\u0bb2\u0bc8 2009 \u0b87\u0bb2\u0bcd, \u0ba8\u0bbe\u0b99\u0bcd\u0b95\u0bb3\u0bcd $1.9 \u0bae\u0bbf\u0bb2\u0bcd\u0bb2\u0bbf\u0baf\u0ba9\u0bc8 \u0ba4\u0bbf\u0bb0\u0b9f\u0bcd\u0b9f\u0bbf\u0baf\u0bc1\u0bb3\u0bcd\u0bb3\u0bcb\u0bae\u0bcd!<\/em><\/p>\n<\/div>\n<div>\n<div><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignleft\" src=\"https:\/\/web.archive.org\/web\/20170218013638im_\/https:\/\/www.progeriaresearch.org\/assets\/images\/donate_images\/Circle_of_Hope_4sm.jpg\" alt=\"\" width=\"125\" height=\"130\" align=\"left\" \/><\/strong><\/div>\n<p><strong>\u0b8e\u0b99\u0bcd\u0b95\u0bb3\u0bcd <a href=\"https:\/\/www.progeriaresearch.org\/ta\/circle-of-hope-3\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u0ba8\u0bae\u0bcd\u0baa\u0bbf\u0b95\u0bcd\u0b95\u0bc8 \u0bb5\u0b9f\u0bcd\u0b9f\u0bae\u0bcd<\/a> \u0bb5\u0bbf\u0bb0\u0bbf\u0bb5\u0b9f\u0bc8\u0ba8\u0bcd\u0ba4\u0ba4\u0bc1\u2026<\/strong><\/p>\n<\/div>\n<div>\u00a0<\/div>\n<div>2006 \u0b86\u0bae\u0bcd \u0b86\u0ba3\u0bcd\u0b9f\u0bbf\u0bb2\u0bcd, \u0b8e\u0b99\u0bcd\u0b95\u0bb3\u0bcd \u0b9a\u0bc6\u0bb2\u0bcd \u0bb5\u0b99\u0bcd\u0b95\u0bbf, \u0ba8\u0bcb\u0baf\u0bb1\u0bbf\u0ba4\u0bb2\u0bcd \u0b9a\u0bcb\u0ba4\u0ba9\u0bc8, \u0b86\u0bb0\u0bbe\u0baf\u0bcd\u0b9a\u0bcd\u0b9a\u0bbf \u0bae\u0bbe\u0ba9\u0bbf\u0baf\u0bae\u0bcd \u0bae\u0bb1\u0bcd\u0bb1\u0bc1\u0bae\u0bcd \u0baa\u0bbf\u0bb1 \u0ba4\u0bbf\u0b9f\u0bcd\u0b9f\u0b99\u0bcd\u0b95\u0bb3\u0bc8 \u0bae\u0bc1\u0bb4\u0bc1 \u0bb5\u0bc7\u0b95\u0ba4\u0bcd\u0ba4\u0bbf\u0bb2\u0bcd \u0b87\u0baf\u0b99\u0bcd\u0b95 \u0bb5\u0bc8\u0baa\u0bcd\u0baa\u0ba4\u0bb1\u0bcd\u0b95\u0bbe\u0b95 5 \u0b86\u0ba3\u0bcd\u0b9f\u0bc1\u0b95\u0bb3\u0bc1\u0b95\u0bcd\u0b95\u0bc1 \u0b86\u0ba3\u0bcd\u0b9f\u0bc1\u0b95\u0bcd\u0b95\u0bc1 $100,000 \u0ba4\u0bbf\u0bb0\u0b9f\u0bcd\u0b9f\u0bc1\u0bae\u0bcd \u0bb5\u0b95\u0bc8\u0baf\u0bbf\u0bb2\u0bcd \u0b9a\u0bb0\u0bcd\u0b95\u0bcd\u0b95\u0bbf\u0bb3\u0bcd \u0b86\u0b83\u0baa\u0bcd \u0bb9\u0bcb\u0baa\u0bcd \u0baa\u0bbf\u0bb0\u0b9a\u0bcd\u0b9a\u0bbe\u0bb0\u0bae\u0bcd \u0b89\u0bb0\u0bc1\u0bb5\u0bbe\u0b95\u0bcd\u0b95\u0baa\u0bcd\u0baa\u0b9f\u0bcd\u0b9f\u0ba4\u0bc1. \u0b87\u0ba8\u0bcd\u0ba4 \u0ba8\u0bbf\u0ba4\u0bbf \u0ba4\u0bbf\u0bb0\u0b9f\u0bcd\u0b9f\u0bc1\u0bae\u0bcd \u0b87\u0bb2\u0b95\u0bcd\u0b95\u0bc8 \u0b85\u0b9f\u0bc8\u0bb5\u0ba4\u0bc1, \u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe \u0b86\u0bb0\u0bbe\u0baf\u0bcd\u0b9a\u0bcd\u0b9a\u0bbf\u0baf\u0bbf\u0bb2\u0bcd \u0b85\u0ba4\u0bbf\u0b95\u0bb0\u0bbf\u0ba4\u0bcd\u0ba4\u0bc1 \u0bb5\u0bb0\u0bc1\u0bae\u0bcd \u0b86\u0bb0\u0bcd\u0bb5\u0ba4\u0bcd\u0ba4\u0bc8\u0ba4\u0bcd \u0ba4\u0bca\u0b9f\u0bb0\u0bb5\u0bc1\u0bae\u0bcd, \u0bae\u0bc1\u0ba9\u0bcd\u0ba9\u0bc7\u0bb1\u0bcd\u0bb1\u0ba4\u0bcd\u0ba4\u0bbf\u0ba9\u0bcd \u0bb5\u0bc7\u0b95\u0ba4\u0bcd\u0ba4\u0bc8\u0ba4\u0bcd \u0ba4\u0bca\u0b9f\u0bb0\u0bb5\u0bc1\u0bae\u0bcd \u0b85\u0ba9\u0bc1\u0bae\u0ba4\u0bbf\u0b95\u0bcd\u0b95\u0bc1\u0bae\u0bcd. \u0b92\u0bb0\u0bc1 \u0bb5\u0bb0\u0bc1\u0b9f\u0ba4\u0bcd\u0ba4\u0bbf\u0bb1\u0bcd\u0b95\u0bc1\u0bb3\u0bcd, \u0baa\u0bcd\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe\u0bb5\u0bc1\u0b95\u0bcd\u0b95\u0bc1 \u0b9a\u0bbf\u0b95\u0bbf\u0b9a\u0bcd\u0b9a\u0bc8\u0baf\u0bb3\u0bbf\u0baa\u0bcd\u0baa\u0ba4\u0bb1\u0bcd\u0b95\u0bbe\u0ba9 \u0bae\u0bb0\u0bc1\u0ba8\u0bcd\u0ba4\u0bc1 \u0b9a\u0bcb\u0ba4\u0ba9\u0bc8\u0b95\u0bcd\u0b95\u0bc1 \u0ba8\u0bbf\u0ba4\u0bbf\u0baf\u0bb3\u0bbf\u0b95\u0bcd\u0b95 $2 \u0bae\u0bbf\u0bb2\u0bcd\u0bb2\u0bbf\u0baf\u0ba9\u0bc8 \u0ba4\u0bbf\u0bb0\u0b9f\u0bcd\u0b9f\u0bc1\u0bb5\u0ba4\u0bb1\u0bcd\u0b95\u0bbe\u0ba9 \u0baa\u0bbf\u0bb0\u0b9a\u0bcd\u0b9a\u0bbe\u0bb0\u0ba4\u0bcd\u0ba4\u0bbf\u0ba9\u0bcd \u0bae\u0ba4\u0bcd\u0ba4\u0bbf\u0baf\u0bbf\u0bb2\u0bcd \u0ba8\u0bbe\u0b99\u0bcd\u0b95\u0bb3\u0bcd \u0b87\u0bb0\u0bc1\u0baa\u0bcd\u0baa\u0bcb\u0bae\u0bcd \u0b8e\u0ba9\u0bcd\u0bb1\u0bc1 \u0baf\u0bbe\u0bb0\u0bcd \u0b95\u0bb1\u0bcd\u0baa\u0ba9\u0bc8 \u0b9a\u0bc6\u0baf\u0bcd\u0ba4\u0bbf\u0bb0\u0bc1\u0b95\u0bcd\u0b95 \u0bae\u0bc1\u0b9f\u0bbf\u0baf\u0bc1\u0bae\u0bcd?! \u0b8e\u0b99\u0bcd\u0b95\u0bb3\u0bcd \u0ba8\u0bae\u0bcd\u0baa\u0bbf\u0b95\u0bcd\u0b95\u0bc8 \u0bb5\u0b9f\u0bcd\u0b9f\u0bae\u0bcd \u0baa\u0bbf\u0bb0\u0b9a\u0bcd\u0b9a\u0bbe\u0bb0\u0bae\u0bcd \u0b87\u0baa\u0bcd\u0baa\u0bcb\u0ba4\u0bc1 \u0b87\u0ba8\u0bcd\u0ba4 \u0b9c\u0bbf \u0bae\u0bc1\u0baf\u0bb1\u0bcd\u0b9a\u0bbf\u0baf\u0bc8 \u0b89\u0bb3\u0bcd\u0bb3\u0b9f\u0b95\u0bcd\u0b95\u0bbf\u0baf\u0ba4\u0bc1.<\/div>\n<div>\u00a0<\/div>\n<div>\u0bb5\u0bc8\u0ba4\u0bcd\u0ba4\u0bbf\u0bb0\u0bc1\u0b95\u0bcd\u0b95 \u0b8e\u0b99\u0bcd\u0b95\u0bb3\u0bc1\u0b95\u0bcd\u0b95\u0bc1 \u0b89\u0ba4\u0bb5\u0bc1\u0b99\u0bcd\u0b95\u0bb3\u0bcd <strong>\u0bb5\u0b9f\u0bcd\u0b9f\u0bae\u0bcd <\/strong>\u0b85\u0baa\u0bcd\u0baa\u0b9f\u0bbf\u0baf\u0bc7, \u0b85\u0ba4\u0ba9\u0bbe\u0bb2\u0bcd <strong>\u0ba8\u0bae\u0bcd\u0baa\u0bbf\u0b95\u0bcd\u0b95\u0bc8<\/strong> \u0b9a\u0bbf\u0b95\u0bbf\u0b9a\u0bcd\u0b9a\u0bc8 \u0b92\u0bb0\u0bc1 \u0b86\u0b95\u0bbf\u0bb1\u0ba4\u0bc1 <strong>\u0baf\u0ba4\u0bbe\u0bb0\u0bcd\u0ba4\u0bcd\u0ba4\u0bae\u0bcd.\u00a0<\/strong><a href=\"https:\/\/progeriaresearch.donorsupport.co\/-\/XZHJVWZR\">\u0ba4\u0bbe\u0ba9\u0bae\u0bcd \u0b9a\u0bc6\u0baf\u0bcd<\/a> \u0b87\u0ba9\u0bcd\u0bb1\u0bc1.<\/div>\n<div><em>\u00a0<\/em><\/div>\n<div><strong>\u0baa\u0bc1\u0bb0\u0bcb\u0b9c\u0bc0\u0bb0\u0bbf\u0baf\u0bbe\u0bb5\u0bc1\u0b95\u0bcd\u0b95\u0bc1 \u0b9a\u0bbf\u0b95\u0bbf\u0b9a\u0bcd\u0b9a\u0bc8\u0baf\u0bb3\u0bbf\u0baa\u0bcd\u0baa\u0ba4\u0bb1\u0bcd\u0b95\u0bbe\u0ba9 \u0ba8\u0bc7\u0bb0\u0bae\u0bcd \u0b87\u0ba4\u0bc1<em>.<\/em><\/strong><\/div>\n<div>\u00a0<strong>\u0b92\u0ba9\u0bcd\u0bb1\u0bbe\u0b95, \u0ba8\u0bbe\u0b99\u0bcd\u0b95\u0bb3\u0bcd\u00a0<em>\u0b89\u0baf\u0bbf\u0bb2\u0bcd<\/em>\u00a0\u0bae\u0bb0\u0bc1\u0ba8\u0bcd\u0ba4\u0bc1 \u0b95\u0ba3\u0bcd\u0b9f\u0bc1\u0baa\u0bbf\u0b9f\u0bbf!<\/strong><\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.22&#8243;][et_pb_row _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.6.5&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;] PRF continues to make history, as nearly all the children enrolled in the trial have come to Children&#8217;s Hospital Boston for their 1-year visit, marking their half-way point to completion. Click here for details on how you can help. Exciting [&hellip;]<\/p>","protected":false},"author":1,"featured_media":11695,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p>[vc_custom_heading text=\"October 2008: First-Ever Progeria Clinical Drug Trial Surpasses Half-Way Mark!\" font_container=\"tag:h1|text_align:left\" use_theme_fonts=\"yes\"]PRF continues to make history, as nearly all the children enrolled in the trial have come to Children's Hospital Boston for their 1-year visit, marking their half-way point to completion. <a href=\"https:\/\/www.progeriaresearch.org\/clinical-trials\/\">Click here<\/a> for details on how you can help.<\/p><p>Exciting times! The Progeria clinical drug trial began on May 7th, 2007 with two children arriving in Boston, MA for their first of seven visits over a 2-year period. At this first visit, they were given extensive tests and their first doses of the drug. An average of two families have been flying to Boston each week since then, and in October 2007, the trial became fully enrolled. The trial is expected to end in October 2009, with results published in 2010.<\/p><div>As of October 1, 2008, all but one child has completed the week-long, 1-year visit.<\/div><div>[caption id=\"attachment_2092\" align=\"alignleft\" width=\"175\"]<img class=\"size-full wp-image-2092\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/Megan-medal-May08.jpg\" alt=\"\" width=\"175\" height=\"275\" \/> Megan proudly wears her 1-year Trial Medal, which she received at the end of her recent trip to Boston[\/caption]<p><strong>\u201cI know of no other rare genetic disease that has gone from gene discovery to clinical trial in under four years - a phenomenal testament to the hard work of The Progeria Research Foundation.\u201d\u00a0<\/strong><\/p><p>\u00a0<\/p>[caption id=\"attachment_2093\" align=\"alignright\" width=\"175\"]<img class=\"size-full wp-image-2093\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/Julieta-Aug07.jpg\" alt=\"\" width=\"175\" height=\"194\" \/> <em><strong>Julieta, from Argentina.<\/strong><\/em>[\/caption]<p>\u00a0<\/p><p><em><strong>Francis Collins, MD, PhD, Director of the National Human Genome Research Institute that mapped the human genome, workshop speaker and co-discoverer of the Progeria gene.<\/strong> <\/em><\/p><\/div><div><strong>Twenty-eight (28) children from sixteen countries<\/strong> are participating, ages 3 to 15 years.\u00a0Children return to Children\u2019s Hospital Boston every four months, for testing and to receive new drug supply, and stay in Boston for 4-8 days each visit. \u00a0While at home, their doctors keep a close watch over the children and submit monthly health reports to the Boston research team.<\/div><div>\u00a0<\/div><div>For the duration of the trial, 1- 2 children per week will travel to Boston to participate.<\/div><div>\u00a0<\/div><div>\u00a0<\/div><div>\u00a0<\/div><div>\u00a0<\/div><div><div>Children Originate from the Following Countries:<\/div><div>\u00a0<\/div><ul><li>Argentina<\/li><li>Belgium<\/li><li>Canada<\/li><li>Denmark<\/li><li>England<\/li><li>India<\/li><li>Israel<\/li><li>Italy<\/li><li>Japan<\/li><li>Mexico<\/li><li>Pakistan<\/li><li>Poland<\/li><li>Portugal<\/li><li>Romania<\/li><li>USA<\/li><li>Venezuela<\/li><\/ul><\/div>[caption id=\"attachment_2094\" align=\"alignleft\" width=\"113\"]<img class=\"size-full wp-image-2094\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/2-megans-frnt-cover.jpg\" alt=\"\" width=\"113\" height=\"225\" \/> \u201cThe two Megans\u201d, both 6 years old, in Boston for the clinical trial[\/caption]<p>\u00a0<\/p>[caption id=\"attachment_2095\" align=\"alignnone\" width=\"200\"]<img class=\"size-full wp-image-2095\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/MichielHayleyJun07.jpg\" alt=\"\" width=\"200\" height=\"177\" \/> Michiel, 8 \u00bd , from Belgium with Hayley, 9 \u00bd , from England in June at Children\u2019s Hospital Boston during their first visit.[\/caption]<p><strong>The<\/strong> <strong>Progeria Clinical Research Drug Trial<\/strong><strong>:\u00a0<\/strong><strong>Who, Where, When, How and How Much\u2026<\/strong><\/p><p><strong>The clinical trial is led by Mark Kieran MD, PhD, <\/strong>Director, Pediatric Medical Neuro-Oncology, Dana-Farber Cancer Institute and Children\u2019s Hospital Boston; Assistant Professor, Departments of Pediatrics and Hematology\/Oncology, Harvard Medical School.\u00a0Dr. Kieran is a pediatric oncologist with extensive experience with the drug under study (farnesyltransferase, or FTI) in children.<\/p><div>The clinical trial is a collaborative effort.\u00a0The children are being seen by physicians at <strong>Children\u2019s Hospital Boston, Dana-Farber Cancer Institute, and Brigham and Women\u2019s Hospital,<\/strong> all Harvard University institutions.\u00a0In addition, physicians and scientists from<strong> The Warren Alpert Medical School at Brown University, UCLA, and NIH<\/strong> are helping to make this trial a success. Many individuals are working together to perform this research.<\/div><div><strong>\u00a0<\/strong><\/div><div><strong>How did we get to this point?<\/strong> In 2002, The Progeria Research Foundation\u2019s collaborative research team <a href=\"https:\/\/web.archive.org\/web\/20170218013638\/https:\/\/www.progeriaresearch.org\/assets\/plugins\/fckeditor\/editor\/progeria_gene_discovered.html\">discovered the Progeria gene.<\/a>\u00a0\u00a0This discovery not only led to further understanding of Progeria, but scientists now know that studying Progeria can help us learn more about heart disease and the normal aging process that affects us all.<\/div><div>\u00a0<\/div><div>Since\u00a0the\u00a0gene discovery, the support of researchers, clinicians, families of children with Progeria have brought us to another crossroads in the search for a treatment. Researchers have identified\u00a0a potential\u00a0drug treatment\u00a0for children with\u00a0Progeria,\u00a0called farnesyltransferase inhibitors (FTIs), and have conducted studies in the lab that support a human trial with the drug.\u00a0<a href=\"https:\/\/www.progeriaresearch.org\/assets\/plugins\/fckeditor\/editor\/more_studies_provide_strong_support.html\">Click here<\/a>\u00a0for more details on the research.<\/div><div>\u00a0<\/div><div><div><strong>How will this drug work in Progeria?<\/strong><\/div><div>The protein that we believe is responsible for Progeria is called progerin.\u00a0In order to block normal cell function and cause Progeria, a molecule called a \u201cfarnesyl group\u201d must be attached to the progerin protein. FTIs act by blocking (inhibiting) the attachment of the farnesyl group onto progerin. So if the FTI drug can block this farnesyl group attachment in children with Progeria, then progerin may be \u201cparalyzed\u201d and Progeria improved.<\/div><\/div><div>[caption id=\"attachment_2096\" align=\"alignleft\" width=\"375\"]<img class=\"wp-image-2096 size-full\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2017\/05\/FTI-3-cell-image-crpd.jpg\" alt=\"\" width=\"375\" height=\"89\" \/> Progeria cells become normalized when FTIs are applied. Capell et al., PNAS, 2005. Normal cell. Progeria cell. Progeria cell after being treated with FTI[\/caption]<\/div><div><a href=\"https:\/\/www.progeriaresearch.org\/assets\/plugins\/fckeditor\/editor\/the_fti_drug.html\">Click here<\/a> for more information on FTIs.<\/div><div><div><strong>What will the trial cost PRF? <\/strong>\u00a0We estimate the trial will cost PRF $2 million dollars.\u00a0This will pay for clinical testing, translators, flights, food, lodging, and certain medical costs <img class=\"alignright\" src=\"https:\/\/web.archive.org\/web\/20170218013638im_\/https:\/\/www.progeriaresearch.org\/assets\/images\/donate_images\/Capsule-1_9.jpg\" alt=\"\" width=\"150\" height=\"299\" align=\"right\" hspace=\"3\" vspace=\"3\" \/>during that 2 \u00bd year time period.<\/div><div>\u00a0<\/div><div><strong>\u00a0<\/strong><strong>Support the <a href=\"https:\/\/www.progeriaresearch.org\/assets\/plugins\/fckeditor\/editor\/clinical_trial.html\">Progeria Clinical Drug Trial<\/a><\/strong><\/div><div><strong>\u00a0<\/strong><\/div><div><strong><em>Your donation will help make this trial happen.<\/em><\/strong><\/div><div><strong>\u00a0<\/strong><\/div><div><p><em>PRF needs to raise approximately $2 million dollars to fund this trial, and as of July 2009, we have raised $1.9 million!<\/em><\/p><\/div><div><div><strong><img class=\"alignleft\" src=\"https:\/\/web.archive.org\/web\/20170218013638im_\/https:\/\/www.progeriaresearch.org\/assets\/images\/donate_images\/Circle_of_Hope_4sm.jpg\" alt=\"\" width=\"125\" height=\"130\" align=\"left\" \/><\/strong><\/div><p><strong>Our <a href=\"https:\/\/www.progeriaresearch.org\/assets\/plugins\/fckeditor\/editor\/circle_of_hope.html\">Circle of Hope<\/a> has expanded\u2026<\/strong><\/p><\/div><div>\u00a0<\/div><div>In 2006, the Circle of Hope campaign was created to raise $100,000 per year for 5 years to keep our Cell Bank, Diagnostics Testing, research grant funding and other programs running full speed ahead.\u00a0Meeting this fundraising goal would allow us to keep up with the increasing interest in Progeria research, and to continue our pace of progress. Who could have imagined that less than a year later, we would be in the midst of a campaign to raise $2 million to fund a drug trial to treat Progeria?!\u00a0Our Circle of Hope campaign now includes this g undertaking.<\/div><div>\u00a0<\/div><div>Please help us keep the <strong>Circle <\/strong>intact, so the <strong>hope<\/strong> of treatment becomes a <strong>reality.\u00a0<\/strong><a href=\"https:\/\/www.progeriaresearch.org\/assets\/plugins\/fckeditor\/editor\/ways_to_donate\/\">Donate<\/a> today.<\/div><div><em>\u00a0<\/em><\/div><div><strong>This is the time to find a treatment for Progeria<em>.<\/em><\/strong><\/div><div>\u00a0<strong>Together, we\u00a0<em>WILL<\/em>\u00a0find the cure!<\/strong><\/div><\/div>","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-2091","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>First-Ever Progeria Clinical Drug Trial Surpasses Half-Way Mark! - The Progeria Research Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/ta\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/\" \/>\n<meta property=\"og:locale\" content=\"ta_IN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"First-Ever Progeria Clinical Drug Trial Surpasses Half-Way Mark! - The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.22&#8243;][et_pb_row _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.6.5&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;] PRF continues to make history, as nearly all the children enrolled in the trial have come to Children&#8217;s Hospital Boston for their 1-year visit, marking their half-way point to completion. Click here for details on how you can help. Exciting [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.progeriaresearch.org\/ta\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/\" \/>\n<meta property=\"og:site_name\" content=\"The Progeria Research Foundation\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ProgeriaResearch\/\" \/>\n<meta property=\"article:published_time\" content=\"2008-05-16T13:50:49+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-12-10T17:55:01+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/12\/Megan-medal-May08.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"175\" \/>\n\t<meta property=\"og:image:height\" content=\"275\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"gravoc\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@Progeria\" \/>\n<meta name=\"twitter:site\" content=\"@Progeria\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"gravoc\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.progeriaresearch.org\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/\"},\"author\":{\"name\":\"gravoc\",\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#\/schema\/person\/a3c935a81e92242c6a77ae0018542928\"},\"headline\":\"First-Ever Progeria Clinical Drug Trial Surpasses Half-Way Mark!\",\"datePublished\":\"2008-05-16T13:50:49+00:00\",\"dateModified\":\"2020-12-10T17:55:01+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/\"},\"wordCount\":1327,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/ta\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.progeriaresearch.org\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/12\/Megan-medal-May08.jpg\",\"articleSection\":[\"News\"],\"inLanguage\":\"ta-IN\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.progeriaresearch.org\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.progeriaresearch.org\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/\",\"url\":\"https:\/\/www.progeriaresearch.org\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/\",\"name\":\"First-Ever Progeria Clinical Drug Trial Surpasses Half-Way Mark! 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Click here for details on how you can help. Exciting [&hellip;]","og_url":"https:\/\/www.progeriaresearch.org\/ta\/2008\/05\/16\/first-ever-progeria-clinical-drug-trial-surpasses-half-way-mark\/","og_site_name":"The Progeria Research Foundation","article_publisher":"https:\/\/www.facebook.com\/ProgeriaResearch\/","article_published_time":"2008-05-16T13:50:49+00:00","article_modified_time":"2020-12-10T17:55:01+00:00","og_image":[{"width":175,"height":275,"url":"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2020\/12\/Megan-medal-May08.jpg","type":"image\/jpeg"}],"author":"gravoc","twitter_card":"summary_large_image","twitter_creator":"@Progeria","twitter_site":"@Progeria","twitter_misc":{"Written by":"gravoc","Est. reading time":"7 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