{"id":12401,"date":"2021-03-11T21:08:40","date_gmt":"2021-03-12T02:08:40","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=12401"},"modified":"2022-11-14T17:12:14","modified_gmt":"2022-11-14T22:12:14","slug":"exciting-breakthroughs-in-rna-therapeutics-for-progeria","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/ur\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/","title":{"rendered":"\u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u06a9\u06d2 \u0644\u06cc\u06d2 \u0622\u0631 \u0627\u06cc\u0646 \u0627\u06d2 \u0639\u0644\u0627\u062c \u0645\u06cc\u06ba \u062f\u0644\u0686\u0633\u067e \u067e\u06cc\u0634 \u0631\u0641\u062a!"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row admin_label=&#8221;row&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.18.1&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-12360 alignnone size-full aligncenter\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2021\/03\/Carlos.jpg\" alt=\"\" width=\"150\" height=\"300\" \/><\/p>\n<p>\u06c1\u0645 \u0633\u06d2 \u0646\u062a\u0627\u0626\u062c \u0628\u0627\u0646\u0679 \u06a9\u0631 \u0628\u06c1\u062a \u067e\u0631\u062c\u0648\u0634 \u06c1\u06cc\u06ba\u06d4<strong> \u0622\u0631 \u0627\u06cc\u0646 \u0627\u06d2 \u0639\u0644\u0627\u062c \u06a9\u06d2 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<em>\u0646\u06cc\u0686\u0631 \u0645\u06cc\u0688\u06cc\u0633\u0646<\/em>.<\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41591-021-01274-0\">\u0627\u06cc\u06a9 \u0645\u0637\u0627\u0644\u0639\u06c1<\/a>\u0641\u0631\u0627\u0646\u0633\u0633 \u06a9\u0648\u0644\u0646\u0632\u060c \u0627\u06cc\u0645 \u0688\u06cc\u060c \u067e\u06cc \u0627\u06cc\u0686 \u0688\u06cc\u060c NIH \u06a9\u06d2 \u0688\u0627\u0626\u0631\u06cc\u06a9\u0679\u0631 \u06a9\u06cc \u0642\u06cc\u0627\u062f\u062a \u0645\u06cc\u06ba\u060c \u0646\u06d2 \u062f\u06a9\u06be\u0627\u06cc\u0627 \u06a9\u06c1 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0686\u0648\u06c1\u0648\u06ba \u06a9\u0627 \u0639\u0644\u0627\u062c SRP2001 \u0646\u0627\u0645\u06cc \u062f\u0648\u0627 \u0633\u06d2<strong>\u0634\u06c1 \u0631\u06af \u0645\u06cc\u06ba \u0646\u0642\u0635\u0627\u0646 \u062f\u06c1 progerin mRNA \u0627\u0648\u0631 \u067e\u0631\u0648\u0679\u06cc\u0646 \u06a9\u06d2 \u0627\u0638\u06c1\u0627\u0631 \u06a9\u06cc 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\u0637\u0631\u06cc\u0642\u06d2 \u06c1\u06cc\u06ba\u06d4 \u06c1\u0631 \u0645\u0637\u0627\u0644\u0639\u06c1 \u0646\u06d2 \u0645\u0627\u0624\u0633 \u0645\u0627\u0688\u0644\u0632 \u0645\u06cc\u06ba \u0622\u0631 \u0627\u06cc\u0646 \u0627\u06d2 \u06a9\u06d2 \u0645\u062e\u062a\u0644\u0641 \u062d\u0635\u0648\u06ba \u06a9\u0648 \u067e\u0627\u06cc\u0627 \u062c\u0648\u060c \u062c\u0628 \u0646\u0634\u0627\u0646\u06c1 \u0628\u0646\u0627\u06cc\u0627 \u062c\u0627\u062a\u0627 \u06c1\u06d2\u060c \u0639\u0644\u0627\u062c \u06a9\u06d2 \u0644\u06cc\u06d2 \u0627\u06cc\u06a9 \u0645\u0624\u062b\u0631 \u0631\u0627\u0633\u062a\u06c1 \u0641\u0631\u0627\u06c1\u0645 \u06a9\u0631\u062a\u0627 \u06c1\u06d2\u060c \u062c\u0633 \u06a9\u06d2 \u0646\u062a\u06cc\u062c\u06d2 \u0645\u06cc\u06ba <strong>\u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0686\u0648\u06c1\u06d2 \u062c\u0648 \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u06a9\u06d2 \u0633\u0627\u062a\u06be \u067e\u0686\u06be\u0644\u06d2 \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u0645\u06cc\u06ba \u0639\u0644\u0627\u062c \u06a9\u06cc\u06d2 \u06af\u0626\u06d2 \u0627\u0646 \u0633\u06d2 \u06a9\u06c1\u06cc\u06ba \u0632\u06cc\u0627\u062f\u06c1 \u0632\u0646\u062f\u06c1 \u0631\u06c1\u06d2\u06d4<\/strong>\u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0648\u0627\u0644\u06d2 \u0628\u0686\u0648\u06ba \u06a9\u06d2 \u0644\u06cc\u06d2 \u0648\u0627\u062d\u062f FDA \u0633\u06d2 \u0645\u0646\u0638\u0648\u0631 \u0634\u062f\u06c1 \u062f\u0648\u0627\u06d4 \u0645\u0632\u06cc\u062f \u0628\u0631\u0622\u06ba\u060c \u0645\u062d\u0642\u0642\u06cc\u0646 \u0646\u06d2 \u067e\u0627\u06cc\u0627 \u06a9\u06c1 \u0622\u0631 \u0627\u06cc\u0646 \u0627\u06d2 \u0639\u0644\u0627\u062c \u0627\u0648\u0631 \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u06a9\u06d2 \u0633\u0627\u062a\u06be \u0645\u0634\u062a\u0631\u06a9\u06c1 \u0639\u0644\u0627\u062c \u0646\u06d2 \u062c\u06af\u0631 \u0627\u0648\u0631 \u062f\u0644 \u0645\u06cc\u06ba \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u067e\u0631\u0648\u0679\u06cc\u0646 \u06a9\u06cc \u0633\u0637\u062d \u06a9\u0648 \u0627\u067e\u0646\u06d2 \u0637\u0648\u0631 \u067e\u0631 \u06a9\u0633\u06cc \u0627\u06cc\u06a9 \u0639\u0644\u0627\u062c \u0633\u06d2 \u0632\u06cc\u0627\u062f\u06c1 \u0645\u0624\u062b\u0631 \u0637\u0631\u06cc\u0642\u06d2 \u0633\u06d2 \u06a9\u0645 \u06a9\u06cc\u0627\u06d4<\/p>\n<p>&quot;\u06cc\u06c1 \u062f\u0648 \u0627\u0646\u062a\u06c1\u0627\u0626\u06cc \u0627\u06c1\u0645 \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u0627\u0633 \u0628\u0627\u062a \u06a9\u0648 \u0638\u0627\u06c1\u0631 \u06a9\u0631\u062a\u06d2 \u06c1\u06cc\u06ba\u06d4 <strong>\u0627\u06c1\u0645 \u067e\u06cc\u0634\u0631\u0641\u062a \u062c\u0648 \u0627\u0628 \u06c1\u0645 \u067e\u0631 \u06c1\u06cc\u06ba\u06d4<\/strong> \u0679\u0627\u0631\u06af\u0679\u0688 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0639\u0644\u0627\u062c \u06a9\u06d2 \u0634\u0639\u0628\u06d2 \u0645\u06cc\u06ba\u060c&quot; PRF \u06a9\u06d2 \u0645\u06cc\u0688\u06cc\u06a9\u0644 \u0688\u0627\u0626\u0631\u06cc\u06a9\u0679\u0631\u060c \u0688\u0627\u06a9\u0679\u0631 \u0644\u06cc\u0633\u0644\u06cc \u06af\u0648\u0631\u0688\u0646 \u0646\u06d2 \u06a9\u06c1\u0627\u06d4 &quot;\u0645\u06cc\u06ba \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0648\u0627\u0644\u06d2 \u0628\u0686\u0648\u06ba \u06a9\u06d2 \u0644\u06cc\u06d2 \u0622\u0631 \u0627\u06cc\u0646 \u0627\u06d2 \u062a\u06be\u0631\u0627\u067e\u06cc \u06a9\u0648 \u0622\u06af\u06d2 \u0628\u0691\u06be\u0627\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u0627\u0646 \u0634\u0627\u0646\u062f\u0627\u0631 \u0631\u06cc\u0633\u0631\u0686 \u06af\u0631\u0648\u067e\u0648\u06ba \u06a9\u06d2 \u0633\u0627\u062a\u06be \u06a9\u0627\u0645 \u06a9\u0631\u0646\u06d2 \u067e\u0631 \u0628\u06c1\u062a \u062e\u0648\u0634 \u062a\u06be\u0627\u06d4 \u062f\u0648\u0646\u0648\u06ba \u06c1\u06cc \u062f\u0644\u0686\u0633\u067e \u062b\u0628\u0648\u062a \u06a9\u06d2 \u0627\u0635\u0648\u0644\u06cc \u0645\u0637\u0627\u0644\u0639\u06c1 \u06c1\u06cc\u06ba\u060c \u0627\u0648\u0631 <strong>PRF \u06a9\u0644\u06cc\u0646\u06cc\u06a9\u0644 \u0679\u0631\u0627\u0626\u0644\u0632 \u06a9\u06cc \u0637\u0631\u0641 \u0622\u06af\u06d2 \u0628\u0691\u06be\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u067e\u0631\u062c\u0648\u0634 \u06c1\u06d2\u06d4<\/strong> \u062c\u0648 \u0627\u0646 \u0639\u0644\u0627\u062c \u06a9\u06cc \u062d\u06a9\u0645\u062a \u0639\u0645\u0644\u06cc\u0648\u06ba \u06a9\u0648 \u0644\u0627\u06af\u0648 \u06a9\u0631\u062a\u06d2 \u06c1\u06cc\u06ba\u06d4<\/p>\n<p>&nbsp;<\/p>\n<p>-<\/p>\n<p>Erdos, MR, Cabral, WA, Tavarez, UL\u00a0<i>\u0648\u063a\u06cc\u0631\u06c1<\/i>\u00a0\u06c1\u0686\u0646\u0633\u0646 \u2013 \u06af\u0644\u0641\u0648\u0631\u0688 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0646\u0688\u0631\u0648\u0645 \u06a9\u06d2 \u0644\u0626\u06d2 \u0627\u06cc\u06a9 \u0679\u0627\u0631\u06af\u0679\u0688 \u0627\u06cc\u0646\u0679\u06cc \u0633\u06cc\u0646\u0633 \u0639\u0644\u0627\u062c \u0645\u0639\u0627\u0644\u062c\u06c1\u06d4\u00a0<i>\u0646\u06cc\u0679 \u0645\u06cc\u0688<\/i>\u00a0(2021)\u06d4 https:\/\/doi.org\/10.1038\/s41591-021-01274-0<\/p>\n<p>\u067e\u0679\u0627\u0631\u0627\u062c\u0648\u060c \u0627\u06cc\u0645\u060c \u062c\u06cc\u06a9\u0633\u0646\u060c \u0627\u06cc\u0645\u060c \u06a9\u0644\u06cc\u0646\u060c \u0627\u06cc\u0633\u06d4\u00a0<i>\u0648\u063a\u06cc\u0631\u06c1<\/i>\u00a0\u0645\u0646\u0638\u0645 \u0627\u0633\u06a9\u0631\u06cc\u0646\u0646\u06af \u06c1\u0686\u0646\u0633\u0646 \u2013 \u06af\u0644\u0641\u0648\u0631\u0688 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0646\u0688\u0631\u0648\u0645 \u06a9\u06d2 \u0644\u0626\u06d2 \u0639\u0644\u0627\u062c \u06a9\u06d2 \u0627\u06cc\u0646\u0679\u06cc \u0633\u06cc\u0646\u0633 \u0627\u0648\u0644\u06cc\u06af\u0648\u0646\u0648\u06a9\u0644\u06cc\u0648\u0679\u0627\u0626\u0688\u0633 \u06a9\u06cc \u0634\u0646\u0627\u062e\u062a \u06a9\u0631\u062a\u06cc \u06c1\u06d2\u06d4\u00a0<i>\u0646\u06cc\u0679 \u0645\u06cc\u0688<\/i>\u00a0(2021)\u06d4 https:\/\/doi.org\/10.1038\/s41591-021-01262-4<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>\u06c1\u0645 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u06a9\u06cc \u062a\u062d\u0642\u06cc\u0642 \u0645\u06cc\u06ba RNA \u0639\u0644\u0627\u062c \u06a9\u06d2 \u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u06a9\u06d2 \u0628\u0627\u0631\u06d2 \u0645\u06cc\u06ba \u062f\u0648 \u0627\u0646\u062a\u06c1\u0627\u0626\u06cc \u062f\u0644\u0686\u0633\u067e \u067e\u06cc\u0634 \u0631\u0641\u062a \u06a9\u06d2 \u0645\u0637\u0627\u0644\u0639\u06d2 \u06a9\u06d2 \u0646\u062a\u0627\u0626\u062c \u06a9\u0627 \u0627\u0634\u062a\u0631\u0627\u06a9 \u06a9\u0631\u062a\u06d2 \u06c1\u0648\u0626\u06d2 \u0628\u06c1\u062a \u067e\u0631\u062c\u0648\u0634 \u06c1\u06cc\u06ba\u06d4 \u062f\u0648\u0646\u0648\u06ba \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u06a9\u0648 \u062f\u06cc \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0631\u06cc\u0633\u0631\u0686 \u0641\u0627\u0624\u0646\u0688\u06cc\u0634\u0646 (PRF) \u06a9\u06d2 \u062a\u0639\u0627\u0648\u0646 \u0633\u06d2 \u0645\u0627\u0644\u06cc \u0627\u0639\u0627\u0646\u062a \u0641\u0631\u0627\u06c1\u0645 \u06a9\u06cc \u06af\u0626\u06cc \u062a\u06be\u06cc \u0627\u0648\u0631 PRF \u06a9\u06d2 \u0645\u06cc\u0688\u06cc\u06a9\u0644 \u0688\u0627\u0626\u0631\u06cc\u06a9\u0679\u0631 \u0688\u0627\u06a9\u0679\u0631 \u0644\u06cc\u0633\u0644\u06cc \u06af\u0648\u0631\u0688\u0646 \u0646\u06d2 \u0627\u0646 \u06a9\u06cc \u0645\u0634\u062a\u0631\u06a9\u06c1 \u062a\u0635\u0646\u06cc\u0641 \u06a9\u06cc \u062a\u06be\u06cc\u06d4 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\/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/ur\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Exciting breakthroughs in RNA Therapeutics for Progeria! | The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"Two very exciting breakthrough studies on the use of RNA therapeutics in Progeria research.\u00a0 Both studies were co-funded by The Progeria Research Foundation (PRF) and co-authored by PRF\u2019s Medical Director, Dr. Leslie Gordon.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.progeriaresearch.org\/ur\/2021\/03\/11\/exciting-breakthroughs-in-rna-therapeutics-for-progeria\/\" \/>\n<meta property=\"og:site_name\" content=\"The 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therapeutics in Progeria research.\u00a0 Both studies were co-funded by The Progeria Research Foundation (PRF) and co-authored by PRF\u2019s Medical Director, Dr. Leslie Gordon.\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2021\/03\/Carlos-with-crocheted-sloth-cropped.jpg\" \/>\n<meta name=\"twitter:creator\" content=\"@Progeria\" \/>\n<meta name=\"twitter:site\" content=\"@Progeria\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Karen Betournay\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 \u0645\u0646\u0679\u0633\" \/>\n<script type=\"application\/ld+json\" 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