{"id":16611,"date":"2023-03-15T10:12:02","date_gmt":"2023-03-15T14:12:02","guid":{"rendered":"https:\/\/www.progeriaresearch.org\/?p=16611"},"modified":"2025-02-15T17:46:23","modified_gmt":"2025-02-15T22:46:23","slug":"progerinbiomarker","status":"publish","type":"post","link":"https:\/\/www.progeriaresearch.org\/ur\/2023\/03\/15\/progerinbiomarker\/","title":{"rendered":"\u0639\u0644\u0627\u062c \u06a9\u06cc \u062a\u0634\u062e\u06cc\u0635 \u0627\u0648\u0631 \u0632\u0646\u062f\u06af\u06cc \u0645\u06cc\u06ba \u062a\u0648\u0633\u06cc\u0639 \u0645\u06cc\u06ba \u062f\u0644\u0686\u0633\u067e \u062a\u062d\u0642\u06cc\u0642\u06cc \u0633\u0646\u06af \u0645\u06cc\u0644!"},"content":{"rendered":"<p>[et_pb_section fb_built=\u201d1\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d0px|||||\u201d global_colors_info=\u201d{}\u201d][et_pb_row _builder_version=\u201d4.16\u2033 background_size=\u201dinitial\u201d background_position=\u201dtop_left\u201d background_repeat=\u201drepeat\u201d custom_padding=\u201d||5px|||\u201d global_colors_info=\u201d{}\u201d][et_pb_column type=\u201d4_4\u2033 _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_text _builder_version=\u201d4.24.0\u2033 background_size=\u201dinitial\u201d background_position=\u201dtop_left\u201d background_repeat=\u201drepeat\u201d global_colors_info=\u201d{}\u201d]<\/p>\n<h5>\u06c1\u0645 \u0622\u067e \u06a9\u06d2 \u0633\u0627\u062a\u06be \u062f\u0648 \u0633\u0646\u0633\u0646\u06cc \u062e\u06cc\u0632 \u062a\u062d\u0642\u06cc\u0642\u06cc \u0627\u067e \u0688\u06cc\u0679\u0633 \u06a9\u0627 \u0627\u0634\u062a\u0631\u0627\u06a9 \u06a9\u0631\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u067e\u0631\u062c\u0648\u0634 \u06c1\u06cc\u06ba\u060c \u062c\u0648 \u0622\u062c \u062f\u0646\u06cc\u0627 \u06a9\u06d2 \u0633\u0631\u0641\u06c1\u0631\u0633\u062a \u0642\u0644\u0628\u06cc \u062c\u0631\u06cc\u062f\u06d2 \u0645\u06cc\u06ba 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\u06a9\u06cc \u0645\u062a\u0648\u0642\u0639 \u0639\u0645\u0631 \u0627\u0648\u0633\u0637\u0627\u064b 4.5 \u0633\u0627\u0644 \u0628\u0691\u06be \u062c\u0627\u062a\u06cc \u06c1\u06d2\u06d4 \u0648\u06c1 \u06c1\u06d2 <strong>\u0627\u0648\u0633\u0637 \u0639\u0645\u0631 \u0645\u06cc\u06ba 30% \u0633\u06d2 \u0632\u06cc\u0627\u062f\u06c1 \u0627\u0636\u0627\u0641\u06c1\u060c 14.5 \u0633\u0627\u0644 \u0633\u06d2 \u062a\u0642\u0631\u06cc\u0628\u0627\u064b 20 \u0633\u0627\u0644 \u06a9\u06cc \u0639\u0645\u0631 \u062a\u06a9<\/strong>!<\/p>\n<p>] _builder_version=\u201d4.16\u2033 custom_padding=\u201d|||\u201d global_colors_info=\u201d{}\u201d custom_padding__hover=\u201d|||\u201d][et_pb_button button_url=\u201dhttps:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/03\/Progerin-Plasma-Biomarker-press-release-FINAL. button_alignment=\u201dcenter\u201d admin_label=\u201dbiomarker pdf\u201d _builder_version=\u201d4.19.5\u2033 _module_preset=\u201ddefault\u201d button_text_color=\u201d#FFFFFF\u201d \u0628\u0679\u0646_bg_color=\u201d#00B2E2\u2033 \u0648\u06cc\u06ba \u0628\u0679\u0646 button_border_color=\u201d#00B2E2\u2033 background_layout=\u201ddark\u201d global_colors_info=\u201d{}\u201d][\/et_pb_button][et_pb_text _builder_version=\u201d4.19.5\u2033 _module_preset=\u201ddefault\u201d global_colors_info=&quot;}=&quot;<\/p>\n<p style=\"font-weight: 400;\"><strong>&quot;\u0627\u0633 \u067e\u0648\u0688 \u06a9\u0627\u0633\u0679 \u067e\u0631 \u0634\u06cc\u0626\u0631 \u06a9\u06cc \u06af\u0626\u06cc \u0633\u0628 \u0633\u06d2 \u0642\u0627\u0628\u0644 \u0630\u06a9\u0631 \u06a9\u06c1\u0627\u0646\u06cc\u0648\u06ba \u0645\u06cc\u06ba \u0633\u06d2 \u0627\u06cc\u06a9&quot;<br \/><\/strong>\u2013 \u0688\u0627\u06a9\u0679\u0631 \u06a9\u06cc\u0631\u0648\u0644\u06cc\u0646 \u0644\u0627\u0645\u060c \u0639\u0627\u0644\u0645\u06cc \u0634\u06c1\u0631\u062a \u06cc\u0627\u0641\u062a\u06c1 \u062f\u0644 \u06a9\u06cc \u0645\u0627\u06c1\u0631 \u0627\u0648\u0631 \u067e\u0648\u0688 \u06a9\u0627\u0633\u0679 \u06a9\u06cc \u0645\u06cc\u0632\u0628\u0627\u0646 <em>\u0631\u0646 \u067e\u0631 \u06af\u0631\u062f\u0634\u060c <\/em>\u0627\u0633 \u0633\u0641\u0631 \u067e\u0631 \u062c\u0633 \u06a9\u06cc \u0648\u062c\u06c1 \u0633\u06d2 \u06cc\u06c1 \u062f\u0644\u0686\u0633\u067e \u0646\u062a\u0627\u0626\u062c \u0628\u0631\u0622\u0645\u062f \u06c1\u0648\u0626\u06d2\u06d4<em>. <\/em><strong>\u0645\u06a9\u0645\u0644 \u0627\u0646\u0679\u0631\u0648\u06cc\u0648 \u0633\u0646\u06cc\u06ba\u06d4<\/strong> \u0627\u0633 \u0645\u0637\u0627\u0644\u0639\u06c1 \u06a9\u06d2 \u06af\u06c1\u0631\u06d2 \u0627\u062b\u0631\u0627\u062a \u06a9\u06d2 \u0628\u0627\u0631\u06d2 \u0645\u06cc\u06ba \u0628\u0631\u0627\u06c1 \u0631\u0627\u0633\u062a \u0688\u0627\u06a9\u0679\u0631 \u06af\u0648\u0631\u0688\u0646 \u0633\u06d2\u06d4 \u0633\u0646\u0648 <a href=\"https:\/\/r20.rs6.net\/tn.jsp?f=001cLXauJ5R6hFjgU6UNVj8z1ubk-cU5xChRkxoAUyz5uADnaWoiVSXmGDO6nDbCFI6BusWzoswFG0iru8PXvTinayQ2nuBWZkmbHn8pNOQ-qsUB1VpMUndro-VBH-aWDvJUzVgfNvTim0xjz6cUlYUsEKvW6Ac2WVwzATNn1BxwmDhQLC1rKekmK7seL8r8YfP&amp;c=WFQd6JESprJMCu4rKF2oA9DZh92aflFfVggkN5fMTdEL4z9YqYGm8g==&amp;ch=BuG-LaRM92CDJVKzSsfwhIYuKm0CXdEFhP1J1G8vN4oKaWQGcoaRLw==\"><strong>\u06cc\u06c1\u0627\u06ba<\/strong><\/a> <a href=\"https:\/\/r20.rs6.net\/tn.jsp?f=001cLXauJ5R6hFjgU6UNVj8z1ubk-cU5xChRkxoAUyz5uADnaWoiVSXmGDO6nDbCFI6BusWzoswFG0iru8PXvTinayQ2nuBWZkmbHn8pNOQ-qsUB1VpMUndro-VBH-aWDvJUzVgfNvTim0xjz6cUlYUsEKvW6Ac2WVwzATNn1BxwmDhQLC1rKekmK7seL8r8YfP&amp;c=WFQd6JESprJMCu4rKF2oA9DZh92aflFfVggkN5fMTdEL4z9YqYGm8g==&amp;ch=BuG-LaRM92CDJVKzSsfwhIYuKm0CXdEFhP1J1G8vN4oKaWQGcoaRLw==\">(<\/a>6:41 \u0633\u06d2 \u0634\u0631\u0648\u0639)\u06d4<\/p>\n<p>] _builder_version=\u201d4.19.5\u2033 _module_preset=\u201ddefault\u201d button_text_color=\u201d#FFFFFF\u201d \u0628\u0679\u0646_bg_color=\u201d#00B2E2\u2033 button_border_width=\u201d0px\u201d button_border_color=\u20331TP_5T0+ \u067e\u0633 \u0645\u0646\u0638\u0631 =\u201d1TP_5T0\u201d \u067e\u0633 \u0645\u0646\u0638\u0631 global_colors_info=\u201d{}\u201d][\/et_pb_button][et_pb_text _builder_version=\u201d4.19.5\u2033 _module_preset=\u201ddefault\u201d global_colors_info=\u201d{}\u201d]<\/p>\n<p style=\"font-weight: 400;\">\u0627\u0648\u0631 \u062c\u0648\u0646 \u0645\u06cc\u06ba \u062f\u0648 \u0627\u062f\u0627\u0631\u062a\u06cc \u06a9\u0627\u063a\u0630\u0627\u062a <a href=\"https:\/\/www.progeriaresearch.org\/ur\/progerinbiomarker\/#2\">(2) <\/a>\u0627\u0648\u0631 <a href=\"https:\/\/www.progeriaresearch.org\/ur\/progerinbiomarker\/#3\">(3)<\/a> \u0645\u06cc\u06ba \u0634\u0627\u0626\u0639 \u06c1\u0648\u0626\u06d2 \u062a\u06be\u06d2\u06d4 <i>\u06af\u0631\u062f\u0634 <\/i>\u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0648\u0627\u0644\u06d2 \u0628\u0686\u0648\u06ba \u06a9\u06d2 \u0639\u0644\u0627\u062c \u0627\u0648\u0631 \u0639\u0644\u0627\u062c \u06a9\u0648 \u0622\u06af\u06d2 \u0628\u0691\u06be\u0627\u0646\u06d2 \u0627\u0648\u0631 \u0639\u0645\u0631 \u0628\u0691\u06be\u0646\u06d2 \u06a9\u0648 \u0628\u06c1\u062a\u0631 \u0637\u0648\u0631 \u067e\u0631 \u0633\u0645\u062c\u06be\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u0627\u0633 \u0628\u0627\u0626\u06cc\u0648 \u0645\u0627\u0631\u06a9\u0631 \u06a9\u06cc \u0627\u06c1\u0645 \u0627\u06c1\u0645\u06cc\u062a \u06a9\u0648 \u0627\u062c\u0627\u06af\u0631 \u06a9\u0631\u0646\u0627\u06d4<\/p>\n<p>]<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-16634 alignleft\" src=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/03\/Circulation-logo-300x74.jpg\" alt=\"\" width=\"219\" height=\"54\" srcset=\"https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/03\/Circulation-logo-300x74.jpg 300w, https:\/\/www.progeriaresearch.org\/wp-content\/uploads\/2023\/03\/Circulation-logo.jpg 400w\" sizes=\"(max-width: 219px) 100vw, 219px\" \/><\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<p>(1) \u06af\u0648\u0631\u0688\u0646\u060c \u0627\u06cc\u0644 \u0628\u06cc\u060c \u0646\u0648\u0631\u0633\u060c \u0688\u0628\u0644\u06cc\u0648\u060c \u062d\u0645\u0631\u06cc\u0646\u060c \u0627\u06cc\u0633\u060c <em>\u0648\u063a\u06cc\u0631\u06c1<\/em>. \u06c1\u0686\u0646\u0633\u0646-\u06af\u0644\u0641\u0648\u0631\u0688 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0646\u0688\u0631\u0648\u0645 \u06a9\u06d2 \u0645\u0631\u06cc\u0636\u0648\u06ba \u0645\u06cc\u06ba \u067e\u0644\u0627\u0632\u0645\u0627 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646: \u0627\u0645\u06cc\u0648\u0646\u0648\u0633\u06d2 \u062a\u0631\u0642\u06cc \u0627\u0648\u0631 \u06a9\u0644\u06cc\u0646\u06cc\u06a9\u0644 \u062a\u0634\u062e\u06cc\u0635\u06d4 <em>\u06af\u0631\u062f\u0634<\/em>, 2023<\/p>\n<p>(2) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37276254\/\">\u06c1\u0686\u0646\u0633\u0646-\u06af\u0644\u0641\u0648\u0631\u0688 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0646\u0688\u0631\u0648\u0645 \u0645\u06cc\u06ba \u06a9\u0627\u0631\u0688\u06cc\u06a9 \u0627\u0633\u0627\u0645\u0627\u0646\u06cc\u062a\u0627\u0648\u06ba \u06a9\u06cc \u062a\u0631\u0642\u06cc: \u0627\u06cc\u06a9 \u0645\u062a\u0648\u0642\u0639 \u0637\u0648\u0644\u0627\u0646\u06cc \u0645\u0637\u0627\u0644\u0639\u06c1\u06d4<\/a><br \/>Olsen FJ\u060c Gordon LB\u060c Smoot L\u060c Kleinman ME\u060c Gerhard-Herman M\u060c Hegde SM\u060c Mukundan S\u060c Mahoney T\u060c Massaro J\u060c Ha S\u060c Prakash A.<br \/><em>\u06af\u0631\u062f\u0634<\/em>. 2023 \u062c\u0648\u0646 6;147(23):1782-1784\u06d4 doi: 10.1161\/CIRCULATIONAHA.123.064370. Epub 2023 \u062c\u0648\u0646 5\u06d4<\/p>\n<p style=\"font-weight: 400;\">(3) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37276251\/\">\u06c1\u0686\u0646\u0633\u0646-\u06af\u0644\u0641\u0648\u0631\u0688 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0633\u0646\u0688\u0631\u0648\u0645 \u0645\u06cc\u06ba \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u0627\u0648\u0631 \u062f\u0644 \u06a9\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc \u06a9\u06d2 \u0628\u0691\u06be\u0646\u06d2 \u06a9\u0627 \u067e\u062a\u06c1 \u0644\u06af\u0627\u0646\u06d2 \u06a9\u06d2 \u0644\u06cc\u06d2 \u0622\u0633\u0627\u0646\u06cc \u0633\u06d2 \u062f\u0633\u062a\u06cc\u0627\u0628 \u0679\u0648\u0644\u0632\u06d4 <\/a><br \/>Eriksson M\u060c Haugaa K\u060c Rev\u00eachon G.<br \/><em>\u06af\u0631\u062f\u0634<\/em>. 2023 \u062c\u0648\u0646 6;147(23):1745-1747\u06d4 doi: 10.1161\/CIRCULATIONAHA.123.064765. Epub 2023 \u062c\u0648\u0646 5\u06d4<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>\u06c1\u0645\u0627\u0631\u06cc \u062a\u062d\u0642\u06cc\u0642\u06cc \u0679\u06cc\u0645 \u0646\u06d2 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0646 \u06a9\u06cc \u067e\u06cc\u0645\u0627\u0626\u0634 \u06a9\u0631\u0646\u06d2 \u06a9\u0627 \u0627\u06cc\u06a9 \u0627\u06c1\u0645 \u0646\u06cc\u0627 \u0637\u0631\u06cc\u0642\u06c1 \u062f\u0631\u06cc\u0627\u0641\u062a \u06a9\u06cc\u0627 \u06c1\u06d2\u060c \u0632\u06c1\u0631\u06cc\u0644\u0627 \u067e\u0631\u0648\u0679\u06cc\u0646 \u062c\u0648 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u06a9\u0627 \u0633\u0628\u0628 \u0628\u0646\u062a\u0627 \u06c1\u06d2\u06d4 \u0627\u0633 \u062f\u0631\u06cc\u0627\u0641\u062a \u06a9\u06d2 \u0633\u0627\u062a\u06be\u060c \u0633\u0627\u0626\u0646\u0633\u062f\u0627\u0646\u0648\u06ba \u0646\u06d2 \u06cc\u06c1 \u0628\u06be\u06cc \u067e\u0627\u06cc\u0627 \u06a9\u06c1 \u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u0648\u0627\u0644\u06d2 \u0628\u0686\u0648\u06ba \u06a9\u06d2 \u0644\u06cc\u06d2 \u0644\u0648\u0646\u0627\u0641\u0627\u0631\u0646\u06cc\u0628 \u06a9\u0627 \u0637\u0648\u06cc\u0644 \u0645\u062f\u062a\u06cc \u0641\u0627\u0626\u062f\u06c1 \u06c1\u0645\u0627\u0631\u06cc \u0633\u0648\u0686 \u0633\u06d2 \u06a9\u06c1\u06cc\u06ba \u0632\u06cc\u0627\u062f\u06c1 \u06c1\u06d2\u06d4<br \/>\n\u067e\u0631\u0648\u062c\u06cc\u0631\u06cc\u0627 \u06a9\u0645\u06cc\u0648\u0646\u0679\u06cc \u06a9\u06d2 \u0644\u06cc\u06d2 \u0627\u0646 \u062f\u0648 \u0646\u062a\u0627\u0626\u062c \u06a9\u0627 \u06a9\u06cc\u0627 \u0645\u0637\u0644\u0628 \u06c1\u06d2\u061f <\/p>","protected":false},"author":2,"featured_media":16614,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,1],"tags":[],"class_list":["post-16611","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Progerin Biomarker | The Progeria Research Foundation<\/title>\n<meta name=\"description\" content=\"Our research team has discovered a vital new way to measure progerin, the toxic protein that causes Progeria. With this discovery, scientists also found that the long-term benefit of lonafarnib for children with Progeria is greater than we thought. What do these two findings mean for the Progeria community? Read more here\u2026\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.progeriaresearch.org\/ur\/2023\/03\/15\/progerinbiomarker\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Progerin Biomarker | The Progeria Research Foundation\" \/>\n<meta property=\"og:description\" content=\"Our research team has discovered a vital new way to measure progerin, the toxic protein that causes Progeria. With this discovery, scientists also found that the long-term benefit of lonafarnib for children with Progeria is greater than we thought. What do these two findings mean for the Progeria community? 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