The VISION of The Progeria Research Foundation:
A world in which every child with Progeria is cured.
The MISSION of The Progeria Research Foundation:
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Progeria is a rare, fatal, “rapid aging” disease. Without the discovery of new treatments, all children with Progeria will die of heart disease at an average age of 14 years. The Progeria Research Foundation (PRF) was founded in 1999 in response to the complete lack of progress being made to help children with Progeria. Our original mission: to discover the cause, treatments and cure for Progeria. With the 2003 discovery of the cause, and the subsequent discovery of a biological link between Progeria, heart disease and aging, our mission has evolved to its current form. Today, PRF continues to be the only organization in the world solely dedicated to this mission. We have filled a void, taking these precious children out of the background where they had been for over 100 years and putting them and Progeria at the forefront of scientific efforts.
In a relatively short time, we have achieved extraordinary progress towards our mission: the Progeria gene discovery in 2003, first-ever clinical drug trials initiated in 2007, the 2012 results of that first trial being the discovery of the first treatment for Progeria, and the 2018 finding that the treatment extends the children’s lives. In addition, we have achieved extensive global awareness of the condition and PRF’s work, and confirmation of critical biological links between Progeria, heart disease and the aging we all experience. From an obscure, ignored disease to treatment and global recognition – a remarkable timeline in the world of medical research! Our accomplishments are being praised as a “scientific sprint” (John Hamilton, NPR) as we forge ahead in this race against time.
All of this progress is due in large part to the creation of PRF’s research-related programs and services. Developed with insightful determination, they provide the resources needed not only to advance the field of Progeria, but also to discover what Progeria can tell us about heart disease and aging.
With the support of dedicated staff and volunteers, a talented board of directors, courageous families, enthusiastic researchers, and thousands of generous people around the world, we are pushing the field of Progeria forward towards discovery, treatments, and cure. And along the way, we are learning a tremendous amount about ourselves.
Please enjoy the pages of this web site, which detail PRF’s programs, progress and partners. The historic Progeria treatment discovery, tremendous success of our global campaign to identify all children with Progeria, and clinical drug trials and drug discovery are contributing to exciting and productive times as we edge ever-closer to our ultimate goal of a cure.
Your love and support for children with Progeria makes these exciting strides possible.