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Science-driven.
Patient-focused.
Progeria is an ultra-rare, fatal genetic disease characterized by an appearance of accelerated aging. PRF is the only research organization in the world dedicated exclusively to finding treatments and the cure.
Learn About PRF
Learn About Progeria
FEATURED PROGRAM
PRF’s $25 million, multi-year initiative advancing a first-of-its-kind Progeria gene-editing therapy through clinical trials to help us determine if this approach is our path to a cure.
Learn more

Research & Drug Development

WE DON'T WAIT
FOR CURES.
WE BUILD THEM.
PRF provides the leadership, infrastructure, and global coordination to advance discoveries into therapies.
Clinical Trials

Care &
Community

NO FAMILY
WALKS THIS
PATH ALONE.
From the moment of diagnosis through long-term care, PRF connects families with trusted medical guidance, peer support, and a global family who truly understands the unique needs of those affected by Progeria.
Community Resources

News & Events

25+ Years of Impact –
because of donors like you

For more than 25 years, PRF has been setting the standard for ultrarare disease research. Donor and volunteer support has made it possible to identify and support children and families worldwide, fund critical research, and develop therapies that would not exist otherwise. When no clear path from discovery to treatment existed, we built one.

And we’re not done.
VIEW OUR IMPACT
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