Vision
Our vision is a world in which every child with Progeria is cured.
Mission
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Vision
Our vision is a world in which every child with Progeria is cured.
Mission
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Progeria is an ultra-rare, fatal, “rapid-aging” disease that afflicts children who, without the FDA-approved treatment lonafarnib, die of heart disease at an average age of 14.5 years. PRF is the only non-profit organization solely dedicated to finding treatments and the cure for Progeria, and is making phenomenal progress toward that goal.
News
ONEpossible 2025 June 1-July 15. Everywhere
ONEpossible 2025, PRF’s mid-year campaign, kicks off today! Learn how, thanks to YOUR support, PRF is driving every major discovery, ensuring those with Progeria get the unique care they need and leading the charge to the cure!
PRF’s 12th International Scientific Workshop
Join us at our scientific workshop taking place at the Boston Marriott Cambridge Hotel, from October 29-31, 2025, to hear about the latest breakthroughs in Progeria research.
The 2024 Donor Impact Snapshot is here!
Take a look at our newly designed 2024 Donor Impact Snapshot and see the incredible progress we’re making thanks to our amazing team, which includes YOU!
PRF Co-Founders Drs. Leslie Gordon and Scott Berns speak as thought leaders at CiMUS, Spain
The Center for Research in Molecular Medicine and Chronic Diseases (CiMUS) at the University of Santiago in Spain invited PRF co-founders to share their story at a special event on Rare Disease Day 2025.
New clinical trial with the drug Progerinin is officially underway
PRF is thrilled to announce that the first Progerinin clinical trial patient visits are complete!
Get Involved
Our lonafarnib clinical trials enrolled 107 children from 42 different countries to test this now-FDA-approved treatment. Because of your support, these children and young adults are living longer, healthier lives.
About PRF
Your donation helps The Progeria Research Foundation treat children with Progeria today, and cure them in the future.
Meet the Kids
We hope their stories inspire you to support PRF, so those dreams can come true.
Events
SAVE THE DATE!
Night of Wonder Gala, Westin Boston Seaport District Hotel, Boston, MA
November 14, 2026
SAVE THE DATE!
Night of Wonder Gala, Westin Boston Seaport District Hotel, Boston, MA
November 14, 2026
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