Speakers Workshop 2025 - The Progeria Research Foundation

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SCIENTIFIC COMMITTEE

[/et_pb_text][/et_pb_column_inner][/et_pb_row_inner][et_pb_row_inner column_structure=”1_3,1_3,1_3″ _builder_version=”4.27.4″ _module_preset=”default” min_height=”454.3px” custom_margin=”|0px|||false|false” custom_padding=”15px|20px|||false|false” global_colors_info=”{}”][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”LESLIE Gordon, MD, PhD ” position=”The Progeria Research Foundation, Medical Director” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2020/01/Lelsie-1.jpg” admin_label=”LESLIE Gordon, MD, PhD ” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” position_origin_a=”center_center” position_origin_f=”center_center” width=”100%” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Scientific Committee Chair
Speaker and Moderator
Introduction & Greetings; Long-term Natural History Lonafarnib Treatment Trial; Workshop Wrap-Up

Speaker and Moderator
Lipodystrophy in Progeria and Aging

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Speaker
Single-cell analysis reveals the phenotypic landscape of arterial cells in Progeria

[/et_pb_team_member][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Mark Kieran, MD, PhD” position=”Day One Biopharmaceuticals, VP Clinical Development” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2023/08/Mark-Kieran-e1739631554887.jpg” admin_label=”Mark Kieran, MD, PhD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Moderator
Current Treatment Trial Outcomes in Progeria
Workshop Wrap-Up

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SPEAKERS

[/et_pb_text][/et_pb_column_inner][/et_pb_row_inner][et_pb_row_inner column_structure=”1_3,1_3,1_3″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”|0px|||false|false” custom_padding=”17px|20px|||false|false” global_colors_info=”{}”][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Laurence Arbibe, MD, PhD” position=”INSERM Institut Necker Enfants Malades” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/Laurence-Arbibesm.jpg” admin_label=”Laurence Arbibe MD, PhD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker
Unraveling accelerated intestinal ageing in HGPS physiopathology: an integrative approach

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Speaker
Introduction & Greetings

[/et_pb_team_member][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Kan Cao, PhD” position=”University of Maryland College Park” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/Kan-Cao-sm.jpg” admin_label=”Kan Cao, PhD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker
Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature

[/et_pb_team_member][/et_pb_column_inner][/et_pb_row_inner][et_pb_row_inner column_structure=”1_3,1_3,1_3″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”|0px|||false|false” custom_padding=”17px|20px|||false|false” global_colors_info=”{}”][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Francis Collins, MD, PhD” position=”Former Director, Center for Precision Health Research National Human Genome Research Institute National Institutes of Health, Former NIH Distinguished Lecturer” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/Francis-Collinssm.jpg” admin_label=”Francis Collins MD, PhD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker and Moderator
Musical Introduction; ProSPER: PROgeria Streamlined Platform gene Editing for Rare diseases; Workshop Wrap-Up

[/et_pb_team_member][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Sunil Ghelani, MD” position=”Boston Children’s Hospital, Attending Cardiologist” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/SunilGhelani-sm.jpg” admin_label=”Sunil Ghelani, MD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker
First-ever Aortic and Coronary Artery Calcium Computed Tomography Clinical Trial Study in Progeria

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Speaker
Targeting Inflammation to Ameliorate HGPS Pathologies

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Speaker
Introduction & Greetings

[/et_pb_team_member][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Kaylee Halko” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/09/Kayleethumbnail2025.jpg” admin_label=”Kaylee Halko” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_margin=”|0px|||false|false” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Panelist
“Coming of Age” Conversations: Young adults with HGPS as Research Partners

[/et_pb_team_member][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Monica Kleinman, MD” position=”Boston Children’s Hospital and Harvard Medical School” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/Monica-Klienman-sm.jpg” admin_label=”Monica Kleinman, MD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker and Moderator
Phase 2a Progerin in Clinical Treatment Trial for Progeria

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Speaker
ProSPER: PROgeria Streamlined Platform gene Editing for Rare diseases

[/et_pb_team_member][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Shannon Lyon, MD” position=”Brigham and Women’s Hospital” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/Shannon-Lyon-sm.jpg” admin_label=”Shannon Lyon, MD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker
New discoveries in Cardiac Measures of Disease in Progeria and Aging through Echocardiography

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Speaker
Tools for Pivotal Science and Medicine in Progeria: Antibody and Biomarker Assay Development

[/et_pb_team_member][/et_pb_column_inner][/et_pb_row_inner][et_pb_row_inner column_structure=”1_3,1_3,1_3″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”|0px|||false|false” custom_padding=”17px|20px|||false|false” global_colors_info=”{}”][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Silvia Ortega Gutierrez, PhD” position=”Universidad Complutense de Madrid” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/silvia-ortega-gutierrez-2.png” admin_label=”Silvia Ortega Gutierrez, PhD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker
Reduction of progerin levels by small molecules as a new approach for treating Progeria

[/et_pb_team_member][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Nizar Saad, PhD” position=”Abigail Wexner Research Institute, Nationwide Children’s Hospital” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/Nizar-Saad2-sm.jpg” admin_label=”Nizar Saad, PhD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_margin=”|0px|||false|false” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker
Development of a miRNA-based Gene Therapy for Hutchinson-Gilford Progeria Syndrome (HGPS)

[/et_pb_team_member][/et_pb_column_inner][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Ning Shen, PhD” position=”Liangzhu Laboratory, Zhejiang University School of Medicine, Professor” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/02/Ning-Shen-PhD-sm.jpg” admin_label=”Ning Shen, PhD” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Speaker
AI-driven therapeutic antisense oligonucleotide for Hutchinson-Gilford Progeria

[/et_pb_team_member][/et_pb_column_inner][/et_pb_row_inner][et_pb_row_inner column_structure=”1_3,1_3,1_3″ _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”|0px|||false|false” custom_padding=”17px|20px|||false|false” global_colors_info=”{}”][et_pb_column_inner type=”1_3″ saved_specialty_column_type=”3_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_team_member name=”Amber Vandeweert-Wielemans” image_url=”https://www.progeriaresearch.org/wp-content/uploads/2025/09/Amber-V-Thumbnail-2025wksh.jpg” admin_label=”Amber V” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|||on|||||” header_text_align=”center” body_text_color=”#29327A” body_line_height=”1em” position_text_align=”center” position_text_color=”#29327A” position_line_height=”1em” custom_padding=”15px|10px|15px|15px|false|false” border_width_all=”3px” border_color_all=”#00B2E2″ box_shadow_style=”preset1″ global_colors_info=”{}”]

Panelist
“Coming of Age” Conversations: Young adults with HGPS as Research Partners

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Panelist
“Coming of Age” Conversations: Young adults with HGPS as Research Partners

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Progeria and Vascular Calcification: Diet and Treatments

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Panelist
“Coming of Age” Conversations: Young adults with HGPS as Research Partners

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Panelist
“Coming of Age” Conversations: Young adults with HGPS as Research Partners

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