Vision
Our vision is a world in which every child with Progeria is cured.
Mission
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Vision
Our vision is a world in which every child with Progeria is cured.
Mission
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Progeria is an ultra-rare, fatal, “rapid-aging” disease that afflicts children who, without the FDA-approved treatment lonafarnib, die of heart disease at an average age of 14.5 years. PRF is the only non-profit organization solely dedicated to finding treatments and the cure for Progeria, and is making phenomenal progress toward that goal.
News
BIG NEWS: Announcing the launch of a brand-new clinical drug trial!
We’re back at it! PRF is thrilled to announce the start of a new Progeria clinical trial with a new drug called Progerinin.
New York Times | July 24, 2024: A Cure for Progeria Could be on the Horizon
The research is heating up: As reported in the New York Times, the cure for Progeria could be on the horizon!! Our collaborations with top minds in gene editing are paying off, and in the words of former NIH Director, Dr. Francis Collins, may be “the answer to a dream we all want to come true.”
PRF now collaborating with Sentynl Therapeutics, new global owner of lonafarnib treatment (Zokinvy©)
Effective Friday, May 3, Sentynl Therapeutics is responsible for the manufacture and distribution of Zokinvy, the FDA-approved treatment for Progeria.
PRF’s 12th International Scientific Workshop
Join us at our scientific workshop taking place at the Boston Marriott Cambridge Hotel, from October 29-31, 2025, to hear about the latest breakthroughs in Progeria research.
We did it – A decade of top Charity Navigator Ratings!
For the 10th straight year, PRF has earned the highest possible rating by the nation’s most trusted charity evaluator.
Get Involved
Our lonafarnib clinical trials enrolled 107 children from 42 different countries to test this now-FDA-approved treatment. Because of your support, these children and young adults are living longer, healthier lives.
About PRF
Your donation helps The Progeria Research Foundation treat children with Progeria today, and cure them in the future.
Meet the Kids
We hope their stories inspire you to support PRF, so those dreams can come true.