Vision
Our vision is a world in which every child with Progeria is cured.
Mission
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Vision
Our vision is a world in which every child with Progeria is cured.
Mission
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Progeria is an ultra-rare, fatal, “rapid-aging” disease that afflicts children who, without the FDA-approved treatment lonafarnib, die of heart disease at an average age of 14.5 years. PRF is the only non-profit organization solely dedicated to finding treatments and the cure for Progeria, and is making phenomenal progress toward that goal.
News

128th Boston Marathon Official Charity

We’re Hiring!
PRF is seeking an experienced Donor Database Manager to join our team. This is a full-time, hybrid role, where the applicant would need to be able to reliably commute to our Peabody office. We are looking for a passionate, enthusiastic, and analytical individual who is excited about data integrity, loves to improve workflow, and can reform donor data processes.

PRF co-founder serves as thought leader in rare disease drug development
Hear PRF co-founder and Medical Director, Dr. Leslie Gordon, along with long-time colleague Dr. Francis Collins, share their journey in rare disease drug development for NORD educational series.

Exciting research milestones in treatment evaluation and life extension!
Our research team has discovered a vital new way to measure progerin, the toxic protein that causes Progeria. With this discovery, scientists also found that the long-term benefit of lonafarnib for children with Progeria is greater than we thought.
What do these two findings mean for the Progeria community?
Get Involved
Our lonafarnib clinical trials enrolled 100 children from 40 different countries to test this now-FDA-approved treatment. Because of your support, these children and young adults are living longer, healthier lives.
About PRF
Your donation helps The Progeria Research Foundation treat children with Progeria today, and cure them in the future.
Meet the Kids
We hope their stories inspire you to support PRF, so those dreams can come true.