Vision
Our vision is a world in which every child with Progeria is cured.
Mission
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Vision
Our vision is a world in which every child with Progeria is cured.
Mission
To discover treatments and the cure for Progeria and its aging-related disorders, including heart disease.
Progeria is an ultra-rare, fatal, “rapid-aging” disease that afflicts children who, without the FDA-approved treatment lonafarnib, die of heart disease at an average age of 14.5 years. PRF is the only non-profit organization solely dedicated to finding treatments and the cure for Progeria, and is making phenomenal progress toward that goal.
News

ONEpossible 2023
ONEpossible 2023, PRF’s mid-year campaign, kicks off today! Learn how, thanks to YOUR support, PRF continues to make a dramatic impact – both on the length and quality of life for children and young adults with Progeria.

Exciting research milestones in treatment evaluation and life extension!
Our research team has discovered a vital new way to measure progerin, the toxic protein that causes Progeria. With this discovery, scientists also found that the long-term benefit of lonafarnib for children with Progeria is greater than we thought.
What do these two findings mean for the Progeria community?

We’re Hiring!
PRF is seeking an experienced Donor Database Manager to join our team. This is a full-time, hybrid role, where the applicant would need to be able to reliably commute to our Peabody office. We are looking for a passionate, enthusiastic, and analytical individual who is excited about data integrity, loves to improve workflow, and can reform donor data processes.

PRF’s 11th International Scientific Workshop was a success!
Thank you to all of those who attended The Progeria Research Foundation’s 11th International Scientific Workshop – RACE Progeria to the Cure!

Sam Berns TEDx Talk Hits 50 Million Views!!
Wow – exciting news! Sam Berns’ TEDx talk, ‘My Philosophy for a Happy Life,’ has inspired millions around the world, and today hit a new milestone: 50 million views on TEDx.com alone (with a grand total of 95 million times, including on TED.com).
Get Involved
Our lonafarnib clinical trials enrolled 100 children from 40 different countries to test this now-FDA-approved treatment. Because of your support, these children and young adults are living longer, healthier lives.
About PRF
Your donation helps The Progeria Research Foundation treat children with Progeria today, and cure them in the future.
Meet the Kids
We hope their stories inspire you to support PRF, so those dreams can come true.
Events
ONEpossible 2023
June 1 – July 15, 2023: 35% more of everything!
PRF’s 22nd Annual International Race for Research
September 9, 2023, Peabody, MA: (details coming soon!)
ONEpossible 2023
June 1 – July 15, 2023: 35% more of everything!
PRF’s 22nd Annual International Race for Research
September 9, 2023, Peabody, MA: (details coming soon!)